Case Control Study of the Relation between Hyperlipidaemia and Calcific Aortic Valve Stenosis

1997 ◽  
Vol 92 (s36) ◽  
pp. 14P-14P
Author(s):  
PT Wilmshurst ◽  
RN Stevenson ◽  
H Griffiths ◽  
JR Lord
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Lymphocyte-to-monocyte ratio in predicting the calcific aortic valve stenosis in a Chinese case–control study

2020 ◽  
Vol 14 (14) ◽  
pp. 1329-1339
Author(s):  
Xiaochun Ma ◽  
Huibo Ma ◽  
Yan Yun ◽  
Shanghao Chen ◽  
Xiaofeng Zhang ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Case Control Study ◽  
Independent Predictor ◽  
Inverse Correlation ◽  
Case Control ◽  
Lymphocyte To Monocyte Ratio ◽  
Study Results ◽  
Chinese Case ◽  
Control Study

Aim: This study examined the role of lymphocyte-to-monocyte ratio (LMR), an inflammatory biomarker, in predicting the severity of calcific aortic valve stenosis (CAVS) in a Chinese case–control study. Results: The LMR significantly decreased in the patients with CAVS compared with healthy controls. An inverse correlation was observed between the severity of stenosis and LMR in the patients. Additionally, the LMR was identified in the multivariate analysis as an independent predictor of severe CAVS. Conclusion: This study provides evidence of an inverse correlation between the severity of CAVS and LMR. LMR could potentially be applied as an independent predictor of severe CAVS and could be incorporated into a novel predictive model.

scholarly journals FTO Is Associated with Aortic Valve Stenosis in a Gender Specific Manner of Heterozygote Advantage: A Population-Based Case-Control Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139419 ◽  
Author(s):  
Cindy Thron ◽  
Payam Akhyari ◽  
Erhard Godehardt ◽  
Artur Lichtenberg ◽  
Ulrich Rüther ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Heterozygote Advantage ◽  
Specific Manner ◽  
Gender Specific ◽  
Control Study

scholarly journals 705. Factors Associated with Local Invasion in Infective Endocarditis: a Nested Case-control Study

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S403-S403
Author(s):  
Abarna Ramanathan ◽  
James Witten ◽  
Steven M Gordon ◽  
Brian Griffin ◽  
Gosta Pettersson ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Aortic Valve ◽  
Case Control Study ◽  
Cleveland Clinic ◽  
Case Control ◽  
Paravalvular Leak ◽  
Multivariable Logistic Regression Model ◽  
Local Invasion ◽  
Nested Case Control ◽  
Control Study

Abstract Background A substantial proportion of infective endocarditis (IE) cases are complicated by local invasion. The purpose of this study was to identify patient and disease characteristics that increase the odds of local invasion in surgically treated IE patients. Methods This was a nested case-control study. All episodes of IE for patients admitted to Cleveland Clinic from January 1st, 2013 – June 30th, 2016 were identified from the Cleveland Clinic IE Registry. Patients >18 years of age who underwent surgery for IE were included. Data was compiled by manual review of the Electronic Medical Record. Local invasion, defined as peri-annular extension, peri-valvular abscess, intra-cardiac fistula or pseudoaneurysm, was ascertained from the surgical operative note. Associations of selected factors with local invasion were examined in a multivariable logistic regression model. Results Among 510 patients who met inclusion criteria, 206 had local invasion. Mean age was 56 years and 369 (72 %) were male. Overall 344 (67 %) had aortic valve, 228 (45%) mitral valve, and 66 (13%) tricuspid or pulmonic valve involvement. Aortic valve involvement (OR 5.76, 95% CI 3.44 – 9.98), mechanical valve (OR 7.63, 95% CI 3.63 – 17.07), bioprosthetic valve (OR 3.20, 95% CI 1.99 – 5.19), significant paravalvular leak (OR 2.27, 95% CI 1.09 – 4.97), new atrioventricular nodal block (OR 3.05, 95% CI 1.57 – 6.09), Staphylococcus aureus infection (OR 2.11, 95% CI 1.20 – 3.76), coagulase negative staphylococcal infection (OR 2.38, 95% CI1.27 – 4.54), and non- viridans group streptococcal infection (OR 4.21, 95% CI 1.81 – 10.06) were significantly associated with local invasion. Conclusion Intra-cardiac and microorganism factors, but not comorbid conditions, are associated with local invasion in IE. Disclosures All Authors: No reported disclosures

scholarly journals Direct transcatheter aortic valve implantation – one-year outcome of a case control study

2014 ◽  
Vol 4 ◽  
pp. 250-257 ◽  
Author(s):  
Janusz Kochman ◽  
Łukasz Kołtowski ◽  
Zenon Huczek ◽  
Piotr Scisło ◽  
Leopold Bakoń ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Case Control Study ◽  
Case Control ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
One Year ◽  
Valve Implantation ◽  
Control Study

scholarly journals Aortic valve replacement in octogenarians with aortic stenosis: A case-control study

1992 ◽  
Vol 20 (7) ◽  
pp. 1512-1516 ◽  
Author(s):  
Margareta Olsson ◽  
Lars Granström ◽  
Dan Lindblom ◽  
Mårten Rosenqvist ◽  
Lars Rydén
Keyword(s):  
Aortic Valve ◽  
Aortic Stenosis ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Risk factors for degenerative aortic valve disease in India: A case control study

2018 ◽  
Vol 74 (1) ◽  
pp. 33-37
Author(s):  
D.S. Chadha ◽  
S.K. Malani ◽  
P. Bharadwaj ◽  
G. Karthikeyan ◽  
P.K. Hasija
Keyword(s):  
Risk Factors ◽  
Aortic Valve ◽  
Aortic Valve Disease ◽  
Case Control Study ◽  
Case Control ◽  
Valve Disease ◽  
Control Study

scholarly journals Rapid-deployment aortic valve replacement in high-risk patients: A case-control study

2021 ◽  
Vol 13 (1) ◽  
pp. 23-27
Author(s):  
Adama Sawadogo ◽  
An Vinh Bui-Duc ◽  
Nicolas D'Ostrevy ◽  
Lionel Camilleri ◽  
Kasra Azarnoush
Keyword(s):  
High Risk ◽  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Case Control Study ◽  
Case Control ◽  
Study Group ◽  
High Risk Patients ◽  
Risk Patients ◽  
Rapid Deployment ◽  
Control Study

Introduction: Aortic valve stenosis is the most frequent cardiac valve pathology in the western world. In high-risk patients, conventional aortic valve replacement (C-AVR) carries high rates of morbidity and mortality. In the last few years, rapid-deployment valves (RDV) have been developed to reduce the surgical risks. In this work, we aimed to compare the mid-term outcomes of rapid-deployment AVR (RD-AVR) with those of the C-AVR in high-risk patients. Methods: This retrospective case-control study identified 23 high-risk patients who underwent RD-AVR between 12/2015 to 01/2018. The study group was compared with a control group of 46 patients who were retrospectively selected from a database of 687 C-AVR patients from 2016 to 2017 which matched with the study group for age and Euro SCORE II. Results: RD-AVR group presented more cardiovascular risk factors. Euro SCORE II was higher in the RD-AVR group (P=0.06). In the RD-AVR group, we observed significantly higher mean prosthetic size (P<0.001). In-hospital mortality was zero in RD-AVR group versus 2 deaths in C-AVR group. Hospital stay was longer in the RD-AVR group with statistical significance (P=0.03). In the group AVR with associated cardiac procedures, while comparing subgroups RD-AVR versus C-AVR, early mean gradient was lower in the first cited (P=0.02). The overall mean follow-up was 10.9 ± 4.3 months. Conclusion: The RD-AVR technique is reliable and lead to positive outcomes. This procedure provides a much larger size with certainly better flow through the aortic root. It is an alternative to C-AVR in patients recognized to be surgically fragile.

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