Female sex Hormones do not Influence Arterial wall Properties during the Normal Menstrual Cycle

1997 ◽  
Vol 92 (5) ◽  
pp. 487-491 ◽  
Author(s):  
Christine Willekes ◽  
Henk J. Hoogland ◽  
Hans A. Keizer ◽  
Arnold P. Hoeks ◽  
Robert S. Reneman
Keyword(s):  
Menstrual Cycle ◽  
Carotid Artery ◽  
Femoral Artery ◽  
Common Carotid Artery ◽  
Arterial Wall ◽  
Common Femoral Artery ◽  
Cross Sectional ◽  
Wall Properties ◽  
Normal Menstrual Cycle ◽  
The Common

1. In previous studies, the elastic properties of the common carotid artery were found to differ between men and women. In these studies, however, the phase of the menstrual cycle was not taken into consideration. It was the aim of the present study to investigate the effect of changing ovarian hormone levels during the normal menstrual cycle on the arterial wall properties of female large arteries. 2. We investigated the elastic right common carotid artery and the muscular right common femoral artery of normotensive young (18–35 years) female subjects (n = 12). The arterial distensibility and cross-sectional compliance coefficients were determined by the use of a specially designed ultrasonic wall-tracking device and measurements of automatic brachial artery cuff blood pressure. The phase of the menstrual cycle was assessed by ultrasonographic evaluation and measurement of 17β-oestradiol and progesterone blood plasma levels. 3. The distensibility coefficient and the cross-sectional compliance coefficient of both the common carotid and the common femoral artery did not change significantly during the normal menstrual cycle despite evidently changing ovarian hormone levels. 4. We conclude that the menstrual cycle does not influence the arterial wall properties of either the elastic common carotid artery or the muscular common femoral artery.

An Angle-Independent Cross-Sectional Doppler Method for Flow Estimation in the Common Carotid Artery

2020 ◽  
Vol 67 (8) ◽  
pp. 1513-1524
Author(s):  
Luuk van Knippenberg ◽  
Ruud J. G. van Sloun ◽  
Sergei Shulepov ◽  
R. Arthur Bouwman ◽  
Massimo Mischi
Keyword(s):  
Carotid Artery ◽  
Common Carotid Artery ◽  
Cross Sectional ◽  
Flow Estimation ◽  
Doppler Method ◽  
The Common

Nebivolol Improves the Vessel Wall Properties of the Common Carotid Artery

1991 ◽  
Vol 3 (S1) ◽  
pp. 61-63 ◽  
Author(s):  
L. M. A. B. Bortel ◽  
T. Merode ◽  
F. A. M. Smeets ◽  
R. S. Reneman ◽  
J. M. V. Mooij ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Common Carotid Artery ◽  
Vessel Wall ◽  
Wall Properties ◽  
Vessel Wall Properties ◽  
The Common

scholarly journals Carotid Beta Stiffness Association with Thyroid Function

2021 ◽  
Vol 10 (3) ◽  
pp. 420
Author(s):  
Alessandro P. Delitala ◽  
Angelo Scuteri ◽  
Edoardo Fiorillo ◽  
Valeria Orrù ◽  
Edward G. Lakatta ◽  
...  
Keyword(s):  
Heart Rate ◽  
Carotid Artery ◽  
Arterial Stiffness ◽  
Common Carotid Artery ◽  
Local Level ◽  
Elastic Parameter ◽  
Stiffness Index ◽  
Cross Sectional ◽  
The Common ◽  
The Right

Background: Thyroid hormone modulation of cardiovascular function has been associated with cardiovascular disease. Recent evidence suggests that free thyroxine (FT4) levels are associated with an increase in systemic arterial stiffness, but little is known about the effects of FT4 at the local level of the common carotid artery. β-stiffness index is a local elastic parameter usually determined by carotid ultrasound imaging. Methods: We conducted a cross-sectional analysis in the ProgeNIA cohort, including 4846 subjects across a broad age range. For the purpose of this study, we excluded subjects with increased thyrotropin (TSH) levels and those treated with levothyroxine or thyrostatic. We assessed β stiffness, strain, wall–lumen ratio, carotid cross-sectional area (CSA), and stress and flow in the right common carotid artery. We tested whether FT4, heart rate, and their interactions were associated with carotid parameters. Results: FT4 was positively and independently associated with β stiffness index (β = 0.026, p = 0.041), and had a negative association with strain (β = −0.025, p = 0.009). After adding heart rate and the interaction between FT4 and heart rate to the model, FT4 was still associated with the β stiffness index (β = 0.186, p = 0.06), heart rate was positively associated with the stiffness index (β = 0.389, p < 0.001) as well as their interaction (β = 0.271, p = 0.007). Conclusion: This study suggests that higher FT4 levels increase arterial stiffness at the common carotid level, consistent with a detrimental effect on elastic arteries. The effect of FT4 is likely to be primarily attributable to its effect on heart rate.

Alteration of the vessel wall properties of the common carotid artery in essential hypertensives

1990 ◽  
Vol 22 ◽  
pp. S1
Author(s):  
G. Arcaro ◽  
G. Jondeau ◽  
S. Laurent ◽  
A. Lafleche ◽  
A. Hoeks ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Common Carotid Artery ◽  
Vessel Wall ◽  
Wall Properties ◽  
Vessel Wall Properties ◽  
The Common

scholarly journals Regional specific modulation of the glycocalyx and smooth muscle cell contractile apparatus in conduit arteries of tail-suspended rats

2016 ◽  
Vol 120 (5) ◽  
pp. 537-545 ◽  
Author(s):  
Hongyan Kang ◽  
Yubo Fan ◽  
Ping Zhao ◽  
Changhui Ren ◽  
Zhenze Wang ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Carotid Artery ◽  
Abdominal Aorta ◽  
Femoral Artery ◽  
Common Carotid Artery ◽  
Orthostatic Intolerance ◽  
Mrna Levels ◽  
Dependent Manner ◽  
Contractile Apparatus ◽  
The Common

The glycocalyx is a key mechanosensor on the surfaces of vascular cells (endothelial cells and smooth muscle cells), and recently, we reported that the redistribution of the hemodynamic factors in tail-suspended (TS) hindlimb-unloaded rats induces the dimensional adaptation of the endothelial glycocalyx in a regional-dependent manner. In the present study, we investigated the coverage and gene expression of the glycocalyx and its possible relationship with smooth muscle contractility in the conduit arteries from the TS rats. The coverage of the glycocalyx, determined by the area analysis of the fluorescein isothiocyanate-labeled wheat germ agglutinin (WGA-FITC) staining to the cryosections of rat vessels, showed a 27.2% increase in the common carotid artery, a 13.3 and 8.0% decrease in the corresponding abdominal aorta and the femoral artery after 3 wk of tail suspension. The relative mRNA levels of syndecan-2, 3, 4, glypican-1, smooth muscle protein 22 (SM22), smoothelin (SMTN), and calponin were enhanced to 1.40, 1.53, 1.70, 1.90, 2.93, 2.30, and 5.23-fold, respectively, in the common carotid artery of the TS rat. However, both glycocalyx-related genes and smooth muscle contractile apparatus were totally or partially downregulated in the abdominal aorta and femoral artery of the TS rat. A linear positive correlation between the normalized coverage of glycocalyx and normalized mRNA levels of SM22, SMTN, and calponin exists. These results suggest the regional-dependent adaptation of the glycocalyx in simulated microgravity condition, which may affect its mechanotransduction of shear stress to regulate the contractility of the smooth muscle, finally contributing to postspaceflight orthostatic intolerance.

Internal Diameter of the Common Femoral Artery in Patients with Insulin-Dependent Diabetes Mellitus

1988 ◽  
Vol 29 (4) ◽  
pp. 423-425 ◽  
Author(s):  
T. Christensen ◽  
B. Neubauer
Keyword(s):  
Femoral Artery ◽  
Diabetic Complications ◽  
Arterial Wall ◽  
Common Femoral Artery ◽  
Dependent Diabetes Mellitus ◽  
Control Group ◽  
Internal Diameter ◽  
Wall Stiffness ◽  
Insulin Dependent ◽  
The Common

By means of an ultrasonographic technique the systolic and diastolic diameters of the common femoral artery were investigated in a group of 50 young insulin-dependent diabetics selected as being free from late diabetic complications and atherosclerotic involvement. After correction for normal physiologic variations there was no correlation of arterial diameters to duration of diabetes and no statistical difference in relation to a control group. It is known that there is a progressive increase of the arterial wall thickness in medium-sized arteries in diabetes. Therefore, it is concluded that there is a corresponding dilatation of the arteries. The reasons for this dilatation are discussed from a biophysical point of view. Furthermore, it is concluded that the increased arterial wall stiffness caused by an increasing elastic modulus and thickness reflects the earliest changes in the diabetic macroangiopathy. Occlusions and narrowing seem only to exist in patients with severe late diabetic complications.

Sign in / Sign up

Export Citation Format

Share Document