Carotid Beta Stiffness Association with Thyroid Function

Background: Thyroid hormone modulation of cardiovascular function has been associated with cardiovascular disease. Recent evidence suggests that free thyroxine (FT4) levels are associated with an increase in systemic arterial stiffness, but little is known about the effects of FT4 at the local level of the common carotid artery. β-stiffness index is a local elastic parameter usually determined by carotid ultrasound imaging. Methods: We conducted a cross-sectional analysis in the ProgeNIA cohort, including 4846 subjects across a broad age range. For the purpose of this study, we excluded subjects with increased thyrotropin (TSH) levels and those treated with levothyroxine or thyrostatic. We assessed β stiffness, strain, wall–lumen ratio, carotid cross-sectional area (CSA), and stress and flow in the right common carotid artery. We tested whether FT4, heart rate, and their interactions were associated with carotid parameters. Results: FT4 was positively and independently associated with β stiffness index (β = 0.026, p = 0.041), and had a negative association with strain (β = −0.025, p = 0.009). After adding heart rate and the interaction between FT4 and heart rate to the model, FT4 was still associated with the β stiffness index (β = 0.186, p = 0.06), heart rate was positively associated with the stiffness index (β = 0.389, p < 0.001) as well as their interaction (β = 0.271, p = 0.007). Conclusion: This study suggests that higher FT4 levels increase arterial stiffness at the common carotid level, consistent with a detrimental effect on elastic arteries. The effect of FT4 is likely to be primarily attributable to its effect on heart rate.

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Clinical case of a patient with occlusive thrombosis of the right common carotid artery

Medical Journal of the Russian Federation ◽

10.17816/0869-2106-2021-27-1-79-86 ◽

2021 ◽

Vol 27 (1) ◽

pp. 79-86

Author(s):

Anna S. Zotova ◽

Tatyana V. Davydova ◽

Anna M. Snigireva

Keyword(s):

Carotid Artery ◽

Common Carotid Artery ◽

Asymptomatic Patient ◽

Duplex Ultrasound ◽

Carotid Bifurcation ◽

Ultrasound Scanning ◽

Severe Atherosclerosis ◽

The Common ◽

The Right ◽

Color Duplex Ultrasound

The paper presents a case of a patient with floating thrombosis in the right common carotid artery and occlusion of the carotid bifurcation of the right common carotid artery against the background of severe atherosclerosis of the common carotid artery with 70% stenosis. Thrombosis was identified using color duplex ultrasound scanning in an asymptomatic patient. During hospitalization, thrombosis was complicated by a cerebral infarction of the right middle cerebral artery, apparently of embolic origin.

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Distensibility coefficient of the common carotid artery in acute cerebral infarct by M-mode ultrasound: A cross-sectional study

West African Journal of Radiology ◽

10.4103/wajr.wajr_23_17 ◽

2018 ◽

Vol 25 (2) ◽

pp. 90

Author(s):

VishwanathT Thimmaiah ◽

C Anupama

Keyword(s):

Carotid Artery ◽

Common Carotid Artery ◽

Cross Sectional Study ◽

Cerebral Infarct ◽

Sectional Study ◽

Cross Sectional ◽

The Common ◽

Acute Cerebral Infarct ◽

Distensibility Coefficient

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An Angle-Independent Cross-Sectional Doppler Method for Flow Estimation in the Common Carotid Artery

IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control ◽

10.1109/tuffc.2020.2975315 ◽

2020 ◽

Vol 67 (8) ◽

pp. 1513-1524

Author(s):

Luuk van Knippenberg ◽

Ruud J. G. van Sloun ◽

Sergei Shulepov ◽

R. Arthur Bouwman ◽

Massimo Mischi

Keyword(s):

Carotid Artery ◽

Common Carotid Artery ◽

Cross Sectional ◽

Flow Estimation ◽

Doppler Method ◽

The Common

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Variations in the anatomical relationship between the common carotid artery and the internal jugular vein: An ultrasonographic study

Colombia Medica ◽

10.25100/cm.v46i2.1652 ◽

2015 ◽

pp. 54-59 ◽

Cited By ~ 3

Author(s):

Mauricio Umaña Perea ◽

Alberto Federico García ◽

José Luis Castillo García ◽

Luis Alfonso Bustamante Cristancho ◽

Juan Sebastián Martínez Collazos

Keyword(s):

Multivariate Analysis ◽

Carotid Artery ◽

Internal Jugular Vein ◽

Common Carotid Artery ◽

Jugular Vein ◽

Patients Âgés ◽

Anterior Position ◽

Anatomical Relationship ◽

The Common ◽

The Right

Introduction: The internal jugular vein locates anterior or anterolateral to the common carotid artery in two-thirds of the subjects studied by ultrasound when the head is in a rotated position. Aim: To identify variables associated with the anterior location of the internal jugular vein. Methods: Ultrasound examinations were performed with the patients in the supine position, with the head rotated to the opposite side. The proximal third of the neck was visualized transversely with a 7.5-mHz transducer. The relationship between the vessels was described in accordance with the proportion of the artery overlapped by the vein. Univariate comparisons and a multivariate analysis of potential variables that may affect the anatomic relationships were performed. Results: Seventy-eight patients were included, 44 of whom were men. The patients' ages ranged from 17 to 90 years (median 64.0, interquartile range 41-73). The right and left sides were studied 75 and 73 times, respectively. The vein was located lateral to the artery in 24.3% (95%CI= 17.4-32.2) of the studies, anterolateral in 33.8% (95%CI= 26.2-41.4) and anterior in 41.9% (95%CI= 33.9-49.8). The multivariate analysis identified age group (OR= 3.7, 95% CI 2.1-6.4) and, less significantly, the left side (OR= 1.7, 95%CI= 0.8-3.5) and male gender (OR= 1.2, 95%CI= 0.6-2.7) as variables associated with the anterior position of the vein. Conclusión: The anterior position of the internal jugular vein relative to the common carotid artery increases gradually with age. Additionally, left-sided localization and male sex further increased the probability of an anterior position.

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Endothelial shear rate, local and regional vascular stiffness in patients in different stages of atherogenesis

Regional blood circulation and microcirculation ◽

10.24884/1682-6655-2016-15-3-50-56 ◽

2016 ◽

Vol 15 (3) ◽

pp. 50-56

Author(s):

V. V. Genkel ◽

A. O. Salachenko ◽

O. A. Alekseeva ◽

I. I. Shaposhnik

Keyword(s):

Shear Stress ◽

Shear Rate ◽

Carotid Artery ◽

Common Carotid Artery ◽

Carotid Arteries ◽

Vascular Stiffness ◽

Stiffness Index ◽

The Common ◽

Relationship Of ◽

The Relationship

Introduction and purpose. Endothelial cells are subjected to biomechanical stress produced by the bloodstream and tunica media of the vessel. Vascular stiffness and endothelial shear stress have cooperative effects on the endothelial structure and function. However, the relationship of shear stress and arterial stiffness is still poorly understood. The purpose of the study was to assess the relationship of endothelial shear rate and both local and regional vascular stiffness in patients at different stages of the development of atherosclerosis. Methods. The study included 60 patients, 33 men and 27 women. The average age of patients was 54.8±11.7 years. Regional arterial stiffness was assessed by measurement of the pulse wave velocity in the arteries of elastic and muscular types. Local stiffness of the carotid arteries was characterized by Peterson elastic modulus, Young's modulus, stiffness index β, the deformation of the common carotid artery. Endothelial shear rate was measured at the site of the common carotid artery. Results. Average values of carotid endothelial shear rate were equal to 433±127 s-1. Reduced endothelial shear rate in the carotid arteries was associated with an increased Peterson modulus (r = -0.289; p = 0.025) and the stiffness index β (r = -0.280; p = 0.037), and moreover - with decreasing vascular distensibility (r = 0.288; p = 0.026) and deformation (r = 0.296; p = 0.024). Assessment of the relationship between endothelial shear rate and regional vascular stiffness showed weak statistically significant negative correlation of shear rate and PWVcf (r = -0.367; p = 0.014). Conclusion. In study subjects endothelial shear rate reduction in the area of the common carotid artery was associated with an increased Peterson modulus, stiffness index β, decreasing deformation of carotid arteries and increase in aortic stiffness.

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XXII. The development of the branchial arterial arches in birds, with special reference to the origin of the subclavians and carotids

Proceedings of the Royal Society of London ◽

10.1098/rspl.1887.0094 ◽

1887 ◽

Vol 42 (251-257) ◽

pp. 429-432 ◽

Cited By ~ 1

Keyword(s):

Carotid Artery ◽

Special Reference ◽

Aortic Arch ◽

Aortic Root ◽

Common Carotid Artery ◽

Innominate Artery ◽

Adult Bird ◽

Basal Portion ◽

The Common ◽

The Right

According to the theories of Rathke, which are universally accepted at the present day, the subclavian artery is supposed to take its origin from the aortic root or fourth embryonic branchial arterial arch. In the adult bird the subclavian on each side is found springing from, the extremity of an innominate artery along with the common carotid. It is presumed that the right subclavian has been, by a shortening of the aortic arch, carried forwards until it meets and fuses with the base of the common carotid artery; and the left subclavian is regarded as representing by its basal portion the fourth left arch or left primitive aorta.

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Relationship between intima-media thickness of the common carotid artery and arterial stiffness in subjects with and without type 2 diabetes: a case-series report

Cardiovascular Diabetology ◽

10.1186/1475-2840-10-3 ◽

2011 ◽

Vol 10 (1) ◽

pp. 3 ◽

Cited By ~ 30

Author(s):

Manuel Gómez-Marcos ◽

José Recio-Rodríguez ◽

María Patino-Alonso ◽

Cristina Agudo-Conde ◽

Leticia Gómez-Sánchez ◽

...

Keyword(s):

Type 2 Diabetes ◽

Carotid Artery ◽

Arterial Stiffness ◽

Common Carotid Artery ◽

Case Series ◽

Intima Media Thickness ◽

Case Series Report ◽

The Common ◽

Series Report

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Female sex Hormones do not Influence Arterial wall Properties during the Normal Menstrual Cycle

Clinical Science ◽

10.1042/cs0920487 ◽

1997 ◽

Vol 92 (5) ◽

pp. 487-491 ◽

Cited By ~ 32

Author(s):

Christine Willekes ◽

Henk J. Hoogland ◽

Hans A. Keizer ◽

Arnold P. Hoeks ◽

Robert S. Reneman

Keyword(s):

Menstrual Cycle ◽

Carotid Artery ◽

Femoral Artery ◽

Common Carotid Artery ◽

Arterial Wall ◽

Common Femoral Artery ◽

Cross Sectional ◽

Wall Properties ◽

Normal Menstrual Cycle ◽

The Common

1. In previous studies, the elastic properties of the common carotid artery were found to differ between men and women. In these studies, however, the phase of the menstrual cycle was not taken into consideration. It was the aim of the present study to investigate the effect of changing ovarian hormone levels during the normal menstrual cycle on the arterial wall properties of female large arteries. 2. We investigated the elastic right common carotid artery and the muscular right common femoral artery of normotensive young (18–35 years) female subjects (n = 12). The arterial distensibility and cross-sectional compliance coefficients were determined by the use of a specially designed ultrasonic wall-tracking device and measurements of automatic brachial artery cuff blood pressure. The phase of the menstrual cycle was assessed by ultrasonographic evaluation and measurement of 17β-oestradiol and progesterone blood plasma levels. 3. The distensibility coefficient and the cross-sectional compliance coefficient of both the common carotid and the common femoral artery did not change significantly during the normal menstrual cycle despite evidently changing ovarian hormone levels. 4. We conclude that the menstrual cycle does not influence the arterial wall properties of either the elastic common carotid artery or the muscular common femoral artery.

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Septic Bleeding of the Common Carotid Artery Following Total Thyroidectomy: An Atypical Complication

Case Reports in Medicine ◽

10.1155/2010/953282 ◽

2010 ◽

Vol 2010 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

T. Jamaan ◽

J. Raedecke ◽

C. Kayser ◽

K. D. Rueckauer ◽

O. Thomusch

Keyword(s):

Carotid Artery ◽

Total Thyroidectomy ◽

Common Carotid Artery ◽

Hyoid Bone ◽

Thyroglossal Duct Cyst ◽

Bone Pathology ◽

Duct Cyst ◽

Thyroglossal Duct ◽

The Common ◽

The Right

Septic rupture of the common carotid artery following total thyroidectomy may rapidly lead to exsanguination. We present a case report of a 16-year-old girl, diagnosed with a questionable thyroglossal duct cyst. Following the initial operative intervention with local excision of the cyst including resection of the medial part of the hyoid bone, pathology revealed papillary carcinoma. Thus secondary total thyroidectomy with locoregional lymphadenectomy was performed. One week later, a wound infection developed, necessitating lavage and drainage. On the 8th postoperative day, a dramatic bleeding of the right common carotid artery occurred. To our knowledge, this is the first reported case in the literature with a septic bleeding of the common carotid artery following total thyroidectomy after one week.

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