scholarly journals Pilot Study of Audiometric Patterns in Fuchs Corneal Dystrophy

2018 ◽  
Vol 61 (10) ◽  
pp. 2604-2608 ◽  
Author(s):  
Nicholas S. Reed ◽  
Jennifer A. Deal ◽  
Matthew G. Huddle ◽  
Joshua F. Betz ◽  
Bethany E. Bailey ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Noise Exposure ◽  
Low Frequency ◽  
Pure Tone Audiometry ◽  
Corneal Dystrophy ◽  
Population Based ◽  
Health And Nutrition ◽  
Hearing Thresholds ◽  
Nationally Representative ◽  
Objectively Measured

Purpose Although Fuchs corneal dystrophy (FCD) is considered an eye disease, a small number of studies have identified genes related to both FCD and hearing loss. Whether FCD is related to hearing loss is unknown. Method This is a case–control study comparing pure-tone audiometry hearing thresholds in 180 patients with FCD from a hospital-based ophthalmology clinic with 2,575 population-based controls from a nationally representative survey, the National Health and Nutrition Examination Survey (from cycles 2005-06 and 2009-10). Generalized estimating equations were used to compare mean better-hearing ear thresholds in the 2 groups adjusted for age, sex, race, and noise exposure. Results Patients with FCD had higher hearing thresholds (worse hearing) in lower frequencies (mean difference at 0.5 kHz = 3.49 dB HL) and lower hearing thresholds (better hearing) in higher frequencies (difference at 4 kHz = −4.25 dB HL) compared with population-based controls. Conclusion In the first study to use objectively measured hearing, FCD was associated with poorer low-frequency and better high-frequency audiometric thresholds than population controls. Further studies are needed to characterize this relationship.

Vocal Performance Teachers and Hearing Loss

2015 ◽  
Vol 16 (1) ◽  
pp. 15-24
Author(s):  
Vance Gunnell ◽  
Jeff Larsen
Keyword(s):  
Hearing Loss ◽  
Otoacoustic Emissions ◽  
Noise Exposure ◽  
Vocal Performance ◽  
Occupational Noise ◽  
Hearing Conservation ◽  
Occupational Noise Exposure ◽  
Distortion Product ◽  
Hearing Thresholds ◽  
Performance Teachers

Hearing thresholds and distortion product otoacoustic emissions were measured for teachers of vocal performance who were gathered for a national conference. Results showed mean audiometric thresholds to be consistent with noise induced hearing loss, more than what would be expected with normal aging. Years of instruction and age were considered as factors in the hearing loss observed. It was concluded that hearing conservation should be initiated with this group to help raise awareness and protect them from hearing loss due to occupational noise exposure.

scholarly journals Diabetic Retinopathy and Hearing Loss: Results from the Fifth Korean National Health and Nutrition Survey

2021 ◽  
Vol 10 (11) ◽  
pp. 2398
Author(s):  
Yong Un Shin ◽  
Seung Hun Park ◽  
Jae Ho Chung ◽  
Seung Hwan Lee ◽  
Heeyoon Cho
Keyword(s):  
Hearing Loss ◽  
Logistic Regression ◽  
Diabetic Retinopathy ◽  
Old Age ◽  
National Health ◽  
Noise Exposure ◽  
Middle Aged ◽  
Nutrition Survey ◽  
Aged Group ◽  
Health And Nutrition

We investigated the association between the severity of diabetic retinopathy (DR) and hearing loss based on vascular etiology. We used data from the Korean National Health and Nutrition Survey 2010–2012. Adults aged >40 years with diabetes were enrolled. Demographic, socioeconomic, general medical, noise exposure and biochemical data were used. Participants were classified into three groups: diabetes without DR, non-proliferative DR (NPDR), and proliferative DR (PDR); participants were also divided into two groups (middle age (40 ≤ age < 65 years) vs. old age (age ≥ 65 years)). The association between hearing loss and DR was determined using logistic regression analysis. A total of 1045 participants (n = 411, middle-aged group; n = 634, old-age group) were enrolled. Overall, the prevalence of hearing loss was 58.1%, 61.4%, and 85.0% in the no DR, NPDR, and PDR groups, respectively. After adjusting for confounding factors, the logistic regression model showed that there was no significant association between the prevalence of DR and hearing loss in the overall sample. However, the presence of PDR (OR 7.74, 95% CI 2.08–28.82) was significantly associated with hearing loss in the middle-aged group. Middle-aged people with diabetes may have an association between DR severity and hearing loss. The potential role of microvascular diseases in the development of hearing loss, especially in middle-aged patients, could be considered.

scholarly journals Partial Hearing Restoration after ERBB2 Induction in Deafened Adult Mice

2019 ◽  
Author(s):  
Jingyuan Zhang ◽  
Daxiang Na ◽  
Miriam Dilts ◽  
Kenneth S. Henry ◽  
Patricia M. White
Keyword(s):  
Cell Proliferation ◽  
Hearing Loss ◽  
Noise Exposure ◽  
Supporting Cell ◽  
Supporting Cells ◽  
Adult Mice ◽  
Hearing Thresholds ◽  
Brainstem Response ◽  
Noise Damage ◽  
Cochlear Supporting Cells

AbstractNoise induced hearing loss (NIHL) affects over ten million adults in the United States, and there is no biological treatment to restore endogenous function after damage. We hypothesized that activation of signaling from ERBB2 receptors in cochlear supporting cells could mitigate NIHL damage. We used the Tet-On genetic expression system to drive a constitutively active variant of ERBB2 (CA-ERBB2) in cochlear supporting cells three days after permanent noise damage in young adult mice. Hearing thresholds were assessed with auditory brainstem response tests prior to noise damage, and hearing recovery was assessed over a three month period. We evaluated supporting cell proliferation, inner and outer hair cell (IHC and OHC) survival, synaptic preservation, and IHC cytoskeletal alterations with histological techniques. Mice harboring CA-ERBB2 capability had similar hearing thresholds to control littermates prior to and immediately after noise exposure, and incurred similar levels of permanent hearing loss. Two and three months after noise exposure, CA-ERBB2+ mice demonstrated a partial but significant reversal of NIHL threshold shifts at the lowest frequency tested, out of five frequencies (n=19 total mice, p=0.0015, ANOVA). We also observed improved IHC and OHC survival (n=7 total cochleae, p=5 × 10−5, Kruskal-Wallis rank sum test). There was no evidence for sustained supporting cell proliferation. Some mortality was associated with doxycycline and furosemide treatments to induce the Tet-ON system. These data suggest that ERBB2 signaling in supporting cells promotes HC repair and some functional recovery. Funded by NIH R01 DC014261, and grants from the Schmitt Foundation and UR Ventures.

Hearing loss as a predictor for hearing protection attenuation among miners

2021 ◽  
pp. oemed-2020-106838
Author(s):  
Elon D Ullman ◽  
Lauren M Smith ◽  
Marjorie C McCullagh ◽  
Richard L Neitzel
Keyword(s):  
Hearing Loss ◽  
Noise Exposure ◽  
Hearing Threshold ◽  
Weighted Average ◽  
Hearing Protection ◽  
Mining Sites ◽  
Speech In Noise ◽  
Midwestern Usa ◽  
Hearing Thresholds ◽  
Fit Testing

ObjectiveThis study investigated risk factors for poor earplug fit, with a focus on the association between hearing loss and personal attenuation ratings (PARs).MethodsEarplug fit was assessed by obtaining PARs using a real ear at attenuation threshold (REAT) system. Hearing loss was assessed using the unoccluded hearing thresholds measured during the REAT testing and the results of a speech-in-noise test. Potential predictors of PARs were modelled using both simple and multiple linear regression. Hearing loss was the primary predictor of interest.ResultsData were collected from 200 workers at ten above-ground mining sites in the Midwestern USA. Workers reported wearing their hearing protection on average 73.9% of the time in a high noise environment (mean 8-hour time-weighted average noise exposure 85.5 dBA, range 65–103 dBA). One-quarter (26.7%) of workers were found to have a hearing loss (hearing threshold ≥25 dB across 1–4 kHz), and 42% reported symptoms of tinnitus. Workers with a hearing loss had a significantly lower PAR than those without a hearing loss (β=−5.1, SE=1.7).ConclusionsThe results of the adjusted regression models suggest that workers with hearing loss achieved significantly lower PARs than those without hearing loss. This association between hearing loss and hearing protection devices (HPD) fit brings into focus the potential benefit of fit checks to be included in hearing conservation programmes. Workers found to have hearing loss should be prioritised for fit testing, as their hearing impairment may be associated with poor HPD fit.

Academic, behavioural and quality of life outcomes of slight to mild hearing loss in late childhood: a population-based study

2019 ◽  
Vol 104 (11) ◽  
pp. 1056-1063 ◽  
Author(s):  
Jing Wang ◽  
Jon Quach ◽  
Valerie Sung ◽  
Peter Carew ◽  
Ben Edwards ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Child Outcomes ◽  
Hearing Threshold ◽  
Population Based ◽  
Life Outcomes ◽  
Quality Of Life Outcomes ◽  
Hearing Thresholds ◽  
Mild Hearing Loss

ObjectiveTo investigate the associations of hearing thresholds and slight to mild hearing loss with academic, behavioural and quality of life outcomes in children at a population level.MethodsDesign and participants:children aged 11–12 years in the population-based cross-sectional Child Health CheckPoint study within the Longitudinal Study of Australian Children. Audiometry:mean hearing threshold across 1, 2 and 4 kHz (better and worse ear); slight/mild hearing loss (threshold of 16–40 decibels hearing loss (dB HL)). Outcomes: National Assessment Program – Literacy and Numeracy, language, teacher-reported learning, parent and teacher reported behaviour and self-reported quality of life. Analysis:linear regression quantified associations of hearing threshold/loss with outcomes.ResultsOf 1483 children (mean age 11.5 years), 9.2% and 13.1% had slight/mild bilateral and unilateral hearing loss, respectively. Per SD increment in better ear threshold (5.7 dB HL), scores were worse on several academic outcomes (eg, reading 0.11 SD, 95% CI 0.05 to 0.16), parent-reported behaviour (0.06 SD, 95% CI 0.01 to 0.11) and physical (0.09 SD, 95% CI 0.04 to 0.14) and psychosocial (0.06 SD, 95% CI 0.01 to 0.11) Pediatric Quality of Life Inventory (PedsQL). Compared with normally hearing children, children with bilateral slight/mild losses scored 0.2–0.3 SDs lower in sentence repetition, teacher-reported learning and physical PedsQL but not other outcomes. Similar but attenuated patterns were seen in unilateral slight/mild losses.ConclusionsHearing thresholds and slight/mild hearing loss showed small but important associations with some child outcomes at 11–12 years. Justifying hearing screening or intervention at this age would require better understanding of its longitudinal and indirect effects, alongside effective management and appropriate early identification programmes.

A Study of Noise Exposure and Hearing Sensitivity in a High School Woodworking Class

1993 ◽  
Vol 24 (3) ◽  
pp. 167-173 ◽  
Author(s):  
James E. Lankford ◽  
Denise M. West
Keyword(s):  
High School ◽  
Hearing Loss ◽  
Noise Exposure ◽  
Low Noise ◽  
Control Group ◽  
Single Class ◽  
Hearing Sensitivity ◽  
Sound Levels ◽  
Hearing Thresholds ◽  
Technical Drawing

The purpose of this study was to determine if noise in a high school woodworking class could contribute to the incidence of hearing loss. Students in the woodworking class served as the experimental group, and students in a technical drawing class were the control group. Four separate experiments were conducted. Experiment 1 consisted of measuring and comparing the sound levels in the woodworking and the technical drawing class environments. In Experiment 2, dosimetry samples of the students in both classrooms were collected. In Experiment 3, the temporary threshold shifts (TTSs) were determined for students in both groups by assessing hearing thresholds at the beginning and end of a single class period. The focus of Experiment 4 was to determine if a threshold shift had occurred in the hearing of the students in the woodworking class over a semester. Results of this study suggest that hazardous noise levels in the high school woodworking shop caused statistically significant TTS among the students. Relatively low noise doses were recorded, but no significant changes in hearing thresholds from the beginning to the end of the semester were noted. It was concluded that repeated noise exposure in a woodworking class may be a contributing factor to hearing loss among a student population and that a hearing conservation program should be instituted in these high school environments.

scholarly journals Diet quality and hearing loss among middle–older aged adults in the USA: findings from National Health and Nutrition Examination Survey

2019 ◽  
Vol 23 (5) ◽  
pp. 812-820 ◽  
Author(s):  
Qiushi Huang ◽  
Yichen Jin ◽  
Nicholas S Reed ◽  
Yan Ma ◽  
Melinda C Power ◽  
...  
Keyword(s):  
Hearing Loss ◽  
National Health ◽  
Diet Quality ◽  
Longitudinal Design ◽  
Low Frequency ◽  
Inverse Association ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Hearing Function ◽  
The Usa

AbstractObjective:To examine the associations between overall diet quality and hearing function among middle–older aged adults in the USA.Design:Cross-sectional analysis. Diet quality was examined using the Mediterranean Diet Score (MDS), using data from a single 24 h dietary recall. Hearing function was objectively measured by audiometry assessments and hearing loss, including high- and low-frequency hearing loss, was defined as pure-tone averages at specific ranges of hearing frequencies >25 dB. Weighted logistic regression analyses were performed to examine the associations of MDS (scored 0–9, categorized at the median as ≤3 or >3) with hearing loss and high- and low-frequency hearing loss.Setting:National Health and Nutrition Examination Surveys 2000–2006 and 2009–2012.Participants:Adults aged ≥50 years (n 1639) with valid dietary and audiometry assessments.Results:After adjusting for potential confounders, a non-significant trend for a protective association of higher MDS was observed for hearing loss (OR = 0·78; 95 % CI 0·49, 1·23). A significant inverse association was observed for high-frequency hearing loss (OR = 0·64; 95 % CI 0·43, 0·95). No association was found for low-frequency hearing loss among women; however, higher MDS was significantly associated with higher odds of low-frequency hearing loss among men (OR = 2·63; 95 % CI 1·39, 4·95).Conclusions:Among middle–older aged adults, adherence to a Mediterranean-style diet was inversely associated with hearing loss, including those at high hearing frequencies, among older adults. However, a detrimental association was observed at low hearing frequencies among men. Future investigations with a longitudinal design are needed to clarify the associations between diet quality and hearing loss.

scholarly journals Audiologic Profile in Patients with Ankylosing Spondylitis: A Controlled Study of 30 Patients

2018 ◽  
Vol 97 (9) ◽  
pp. E18-E22 ◽  
Author(s):  
Lumy Yagueshita ◽  
Lucas Resende Lucinda ◽  
Valderilio Azevedo ◽  
Gislaine Richter Minhoto Wiemes ◽  
Nicole Richter Minhoto Wiemes ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Sensorineural Hearing Loss ◽  
Functional Status ◽  
Pure Tone Audiometry ◽  
Sensorineural Hearing ◽  
Controlled Study ◽  
Hearing Thresholds ◽  
Significant Difference

Recent studies have identified sensorineural hearing loss as a possible manifestation of ankylosing spondylitis. We conducted a study of 30 patients with ankylosing spondylitis to characterize their audiologic profile and to correlate their disease activity and functional indices with their hearing thresholds. The study group was made up of 18 men and 12 women, aged 25 to 58 years (mean: 46.5), who were diagnosed with ankylosing spondylitis. We compared their findings with a socially and demographically matched group of 30 healthy controls. All 60 participants underwent an audiologic assessment, consisting of pure-tone audiometry, speech audiometry, and tympanometry. We used validated indices to assess disease activity and functional status, and we compiled information on the time of diagnosis and the types of medications used to treat the ankylosing spondylitis. We found that the average of the mean air-conduction thresholds at 0.5, 1, 2, and 4 kHz in the ankylosing spondylitis group was significantly worse than that of the controls (p = 0.004). A statistically significant difference was observed at frequencies greater than 3 kHz (p < 0.05). A subgroup of case patients who used only a tumor necrosis factor-alpha inhibitor exhibited better hearing thresholds than patients who used other drugs (p = 0.01). Differences in functional and disease activity scores between case patients with and without hearing loss were not statistically significant. We found that patients with ankylosing spondylitis did indeed have a greater prevalence of sensorineural hearing loss but that it was not correlated with either disease activity or functional status.

scholarly journals Contributing Determinants to Hearing Loss in Elderly Men and Women: Results from the Population-Based Rotterdam Study

2016 ◽  
Vol 21 (Suppl. 1) ◽  
pp. 10-15 ◽  
Author(s):  
Stephanie C. Rigters ◽  
Mick Metselaar ◽  
Marjan H. Wieringa ◽  
Robert J. Baatenburg de Jong ◽  
Albert Hofman ◽  
...  
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Pure Tone Audiometry ◽  
Inverse Correlation ◽  
Population Based ◽  
Rotterdam Study ◽  
Cross Sectional ◽  
Men And Women ◽  
Age Related ◽  
Age Related Hearing Loss

To contribute to a better understanding of the etiology in age-related hearing loss, we carried out a cross-sectional study of 3,315 participants (aged 52-99 years) in the Rotterdam Study, to analyze both low- and high-frequency hearing loss in men and women. Hearing thresholds with pure-tone audiometry were obtained, and other detailed information on a large number of possible determinants was collected. Hearing loss was associated with age, education, systolic blood pressure, diabetes mellitus, body mass index, smoking and alcohol consumption (inverse correlation). Remarkably, different associations were found for low- and high-frequency loss, as well as between men and women, suggesting that different mechanisms are involved in the etiology of age-related hearing loss.

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