Hearing in Mice by GSR Audiometry: II. Magnitude of Unconditioned GSR as a Function of Intensity and Frequency Interactions

1968 ◽  
Vol 11 (1) ◽  
pp. 169-178 ◽  
Author(s):  
Alan Gill ◽  
Charles I. Berlin

The unconditioned GSR’s elicited by tones of 60, 70, 80, and 90 dB SPL were largest in the mouse in the ranges around 10,000 Hz. The growth of response magnitude with intensity followed a power law (10 .17 to 10 .22 , depending upon frequency) and suggested that the unconditioned GSR magnitude assessed overall subjective magnitude of tones to the mouse in an orderly fashion. It is suggested that hearing sensitivity as assessed by these means may be closely related to the spectral content of the mouse’s vocalization as well as to the number of critically sensitive single units in the mouse’s VIIIth nerve.

1984 ◽  
Vol 56 (2) ◽  
pp. 404-410 ◽  
Author(s):  
W. R. Revelette ◽  
F. W. Zechman ◽  
D. E. Parker ◽  
R. L. Wiley

The effect of background loading on magnitude estimation of added elastic and resistive inspiratory loads was determined. An analogous study involving estimation of the heaviness of weights in the hand was also performed. Perceptual performance was assessed using Stevens' power law psi = k phi n, where psi is the subjective magnitude, phi is the peak mouth pressure generated with an inspiratory load or the weight of the load in grams for the heaviness estimation, and the exponent n characterizes perceptual performance. The value of n was determined for the control and background conditions for each study. The results for both inspiratory loading studies and the heaviness estimation experiment indicate that background loading is associated with a significant increase in the exponent for magnitude estimation (P less than 0.05). Adjustment of the stimulus scale by subtracting the difference in peak mouth pressures generated during resting breathing between control and background-loaded conditions for the inspiratory loading studies, or the weight of the background load in the heaviness estimation experiment, converted the exponents obtained under background-loaded conditions to values that were not significantly different from those for control (P greater than 0.05). These results are consistent with the theory suggesting that an increase in detection threshold, produced by the background load, is responsible for the increase in exponent for magnitude estimation.


1997 ◽  
Vol 15 (3) ◽  
pp. 345-354 ◽  
Author(s):  
P. N. Vijayakumar ◽  
P. K. Pasricha

Abstract. An important component of ionospheric plasma irregularity studies in the Indian low latitudes involves the study of the plasma bubbles which produce intense scintillations of the transionospheric satellite signals. Many such plasma bubble induced (PBI) scintillation events were identified while recording 244 MHz signal from the geostationary satellite Fleetsat (73°E) at Delhi (28.6°N, 77.2°E) during March-April 1991. This type of scintillations represents changes in plasma processes. These scintillations are spectrally analyzed using an autoregressive (AR) scheme, which is equivalent to maximum entropy method of spectrum analysis, amenable to extracting optimum spectral content from short data lengths (20 – 40 s). Each spectrum is assigned a level of detectability using the final prediction error (FPE) derived from the optimum filter order required to resolve the spectrum. Lower detectability together with a higher order filter indicate a higher level of coherence for the plasma irregularities (discrete structures). Consistent patterns for these scintillations emerge from the present analysis as follows: (1) the initial and final phases of a scintillation patch display quasiperiodic oscillations. Their corresponding spectra show dominant (Gaussian shaped) spectral features with detectability levels of –6 dB to –12 dB and requiring a higher order (>6) AR filter for their spectral resolution. These are most likely associated with discrete "filament-like" or "sheet-like" plasma structures that exist near the bubble walls. (2) Two main features of the scintillation spectra could be positively associated with the well-developed plasma bubble stage: (a) spectra displaying a power-law process with a single component spectral slope between 1.6 to 3.0. Generally such spectra are resolved with a 2nd order filter and have a 1 dB to 6 dB of detectability. (b) Spectra displaying a double slope, indicating an inner and an outer scale regime for the power-law irregularities. These spectra are resolved with higher order filters (>3 but <7) and possess detectability levels of –1 dB to 3 dB. These spectra display finer spectral changes, perhaps indicative of the nature of continuously evolving plasma irregularities. As an example, an analysis of a single scintillation patch is presented to highlight the geophysical significance of the present approach. Some important parameters used in the AR scheme of spectral analysis are given in the Appendix.


1999 ◽  
Vol 173 ◽  
pp. 289-293 ◽  
Author(s):  
J.R. Donnison ◽  
L.I. Pettit

AbstractA Pareto distribution was used to model the magnitude data for short-period comets up to 1988. It was found using exponential probability plots that the brightness did not vary with period and that the cut-off point previously adopted can be supported statistically. Examination of the diameters of Trans-Neptunian bodies showed that a power law does not adequately fit the limited data available.


Author(s):  
Rick L. Vaughn ◽  
Shailendra K. Saxena ◽  
John G. Sharp

We have developed an intestinal wound model that includes surgical construction of an ileo-cecal patch to study the complex process of intestinal wound healing. This allows approximation of ileal mucosa to the cecal serosa and facilitates regeneration of ileal mucosa onto the serosal surface of the cecum. The regeneration of ileal mucosa can then be evaluated at different times. The wound model also allows us to determine the rate of intestinal regeneration for a known size of intestinal wound and can be compared in different situations (e.g. with and without EGF and Peyer’s patches).At the light microscopic level it appeared that epithelial cells involved in regeneration of ileal mucosa originated from the enlarged crypts adjacent to the intestinal wound and migrated in an orderly fashion onto the serosal surface of the cecum. The migrating epithelial cells later formed crypts and villi by the process of invagination and evagination respectively. There were also signs of proliferation of smooth muscles underneath the migratory epithelial cells.


2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.


1981 ◽  
Vol 24 (1) ◽  
pp. 3-15 ◽  
Author(s):  
Larry E. Humes ◽  
Fred H. Bess

This manuscript examines the issue of potential decline in hearing sensitivity due to hearing aid usage through an analysis of data obtained from the temporary threshold shift (TTS) paradigm. Following a critique of the traditional measures of TTS, the concept of integrated TTS (ITTS) is reviewed and data on hearing-aid-induced ITTS are presented. In addition, a series of equations relating permanent threshold shift (PTS) to a recently developed measure of noise dose (Dn) is derived and predictions for hearing-aid-induced PTS are made. Recommended gain settings established to protect the hearing of a person wearing a hearing aid from further decline following various durations of hearing aid usage are also provided.


1963 ◽  
Vol 6 (4) ◽  
pp. 359-368 ◽  
Author(s):  
Charles I. Berlin

Hearing in mice has been difficult to measure behaviorally. With GSR as the basic tool, the sensitivity curve to pure tones in mice has been successfully outlined. The most sensitive frequency-intensity combination was 15 000 cps at 0-5 dB re: 0.0002 dyne/cm 2 , with responses noted from 1 000 to beyond 70 000 cps. Some problems of reliability of conditioning were encountered, as well as findings concerning the inverse relationship between the size of GSR to unattenuated tones and the sound pressure necessary to elicit conditioned responses at or near threshold. These data agree well with the sensitivity of single units of the eighth nerve of the mouse.


1968 ◽  
Vol 11 (2) ◽  
pp. 334-342 ◽  
Author(s):  
Gretchen B. Henry ◽  
Donald C. Teas

Averaged evoked responses to noise burst signals at six sensation levels were obtained in three experimental contexts and compared on the basis of response magnitude. No significant effects were found related to context; systematic differences were found, however, within the ensemble of responses making up the average. These differences suggest that the maximum estimate of response magnitude may be contained in the first few responses to a series of stimuli.


2007 ◽  
Vol 23 (3) ◽  
pp. 157-165 ◽  
Author(s):  
Carmen Hagemeister

Abstract. When concentration tests are completed repeatedly, reaction time and error rate decrease considerably, but the underlying ability does not improve. In order to overcome this validity problem this study aimed to test if the practice effect between tests and within tests can be useful in determining whether persons have already completed this test. The power law of practice postulates that practice effects are greater in unpracticed than in practiced persons. Two experiments were carried out in which the participants completed the same tests at the beginning and at the end of two test sessions set about 3 days apart. In both experiments, the logistic regression could indeed classify persons according to previous practice through the practice effect between the tests at the beginning and at the end of the session, and, less well but still significantly, through the practice effect within the first test of the session. Further analyses showed that the practice effects correlated more highly with the initial performance than was to be expected for mathematical reasons; typically persons with long reaction times have larger practice effects. Thus, small practice effects alone do not allow one to conclude that a person has worked on the test before.


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