Children's Speech Revisions for a Familiar and an Unfamiliar Adult

1984 ◽  
Vol 27 (3) ◽  
pp. 359-363 ◽  
Author(s):  
Michael Tomasello ◽  
Michael Jeffrey Farrar ◽  
Jennifer Dines

Initial characterizations of the communicative abilities of preschoolers stressed their egocentric nature. Recently, however, even 2-year-olds have been observed to adjust their speech appropriately in situations in which the listener provides feedback by signaling noncomprehension. The current study had an adult signal noncomprehension to the requests of 2-year-old Stage I and Stage II children. Each child interacted with a familiar (mother) and an unfamiliar adult. The children repeated their requests about one third of the time and revised them about two thirds of the time. Stage I children elaborated their requests significantly more often than Stage II children. The familiarity of the adult listener had no effect on the way Stage II children revised their requests, but the Stage I children's revisions contained novel lexical items more often when they were interacting with the unfamiliar adult. Both of these findings may have resulted from the fact that the more conversationally skilled Stage II children relied on verbal-conversational cues, which were the same for both adult interactants in this situation. The Stage I children may have been less aware of these conversational cues, relying on general social cues such as familiarity of the interactant. The results are discussed in terms of the potential role of different types of adults in the language acquisition process.

1988 ◽  
Vol 6 (11) ◽  
pp. 1722-1727 ◽  
Author(s):  
W J Curran ◽  
M J Kornstein ◽  
J J Brooks ◽  
A T Turrisi

To evaluate the role of mediastinal irradiation (RT) following surgery for invasive thymomas, a clinical and pathologic review of 117 patients with the diagnosis of thymoma was completed. Fourteen cases were excluded because of the lack of histologic criteria for a thymic tumor, and the remaining 103 were classified according to a staging system as follows: stage I, completely encapsulated (43); stage II, extension through the capsule or pericapsular fat invasion (21); stage III, invasion of adjacent structures (36); and stage IV, thoracic dissemination or metastases (3). The 5-year actuarial survival and relapse-free survival rates were 67% and 100% for stage I, 86% and 58% for stage II, and 69% and 53% for stage III. No recurrences occurred among stage I patients after total resection without RT. However, eight of 21 patients with invasive (stage II or III) thymomas had mediastinal recurrence as the first site of failure following total resection without RT. The 5-year actuarial mediastinal relapse rate of 53% in this group compares unfavorably with the mediastinal relapse rate seen among stage II or III cases following total resection with RT (0%) or following subtotal resection/biopsy with RT (21%). Despite attempted salvage therapy, five of eight patients with mediastinal relapse following total resection alone died of progressive disease. No significant difference was observed in the local relapse rate, overall relapse rate, or survival between those patients undergoing biopsy and RT v subtotal resection and RT for invasive thymomas (stages II and III). Total resection alone appears to be inadequate therapy resulting in an unacceptably high local failure rate with poor salvage therapy results.


2021 ◽  
Vol 32 (4) ◽  
pp. 305-326
Author(s):  
Vadim V. Dementyev ◽  

The article deals with heart-moving stories about kitties published on the Internet by the Moscow adoption center for cats “Murkosha”, which are studied in connection with the dominants of the volunteer discourse. The article focuses on speech genre and narrative characteristics of these stories. It is shown that their specific language, text, and other features are secondary to the main goal – to influence the reader, to induce him either to take the cat directly or to help the adoption center financially. Accordingly, the means that make it possible to enhance the impact come to the fore: expression, different types of direct appeal to moral imperatives, playing with values; at the syntax level – an abundance of direct and indirect directives. The author shows some speechgenre connections of the heart-moving stories about kitties with other genres of volunteer and non-volunteer (advertising) discourse: they are united by the role of indirect communication in text-building and (usually not directly named) practical illocutionary goal; but they demostrate a different attitude to the values that the author of the heart-moving stories about kitties operates (among them the main one is the increase in the amount of love and goodness in the world). The cat is presented in a humanized form (the method of personification) (hence, and not only from “advertising” intentionality, there is a lot of indirect communication, including metaphors, pastiche of various “human” genres), most often as a child. Hence – many “children’s” genres, imitation of the features of children’s speech and speech of adults in communication with children. The method of personification determines the greatest variety of expressive means when describing the “most metaphorical” components of a cat’s image (frame actants): the “character” of the cat and the “communication” (friendship, love) of the cat and the owner. The article analyzes illocutionary types of heart-moving stories about kitties, identified by the authors themselves and marked with smilies (emergency message for help; the story of a cat that entered the adoption center and is ready to be handed over to the future owner; a message about the need for especially careful treatment of a cat with physical or psychological problems; an adoption center that found a family; “letter from home” from new owners) and narrative types (narrative with partially expressed authorship; mixed (authorship) narratives; pastiche of the “dialogue” of a cat with an adoption center employee; “narrative” on behalf of a cat, etc.). A separate micro-study deals with the heart-moving stories frame structure, where the actants / slots are distinguished: a cat (external data, diseases, and other physical and / or psychological problems, “psychology” of a cat); a past owner of a cat, a new or future owner of a cat; street, street life, homelessness, dangers; adoption center for cats “Murkosha” and its staff. There is a characteristic of the use and distribution of linguistic means (primarily expressive: metaphors, especially – conceptual metaphors, definitions, including applications, epithets, etc.) by frame actants and slots. In particular, it is shown that the image of a cat is formed by three meaningful dominants (concepts): love-friendship (as an indissoluble unity) (hence the image of communication happiness), orphanhood and doing good. The latter corresponds to the dominant of the volunteer discourse. Of the two remaining, orphanhood is well combined with it (the targeting of doing good is emphasized), but the latter rather contradicts it (it is more likely mutually beneficial cooperation, even exchange, than disinterested service) and can probably be explained by the focus on the diversity of reaching a heterogeneous audience, where the motives to take a cat from a shelter can also be different.


Author(s):  
Franz Tödtling ◽  
Michaela Trippl ◽  
Alexandra Frangenheim

Abstract Green and sustainable developments have received increasing attention in recent years due to challenges emanating from climate change and worsening environmental conditions. Although these are problems of global nature, actions have to be taken often at lower spatial scales. We focus on innovation and industrial policies and on the regional level since green development often can be supported here by respective policies. However, effective policies have to consider that individual regions face different kinds of challenges for moving towards a ‘greener’ future. This article develops a framework that allows taking such differences into account. We distinguish between the production side of ‘green technologies’ (i.e. the industries that develop and produce such technologies) and the application side (i.e. the adoption of such technologies by firms and the wider society), and we investigate what challenges might prevail on both sides and explore the potential role of policies for different types of regions.


2001 ◽  
Vol 280 (4) ◽  
pp. G546-G554 ◽  
Author(s):  
Asensio Gonzalez ◽  
Sushil K. Sarna

The aim of this study was to investigate the modulation of in vitro rat colonic circular muscle contractions by dextran sodium sulfate (DSS)-induced inflammation and in spontaneous inflammation in HLA-B27 rats. We also examined the potential role of hydrogen peroxide (H2O2) in modulating excitation-contraction coupling. The muscle strips from the middle colon generated spontaneous phasic contractions and giant contractions (GCs), the proximal colon strips generated primarily phasic contractions, and the distal colon strips were mostly quiescent. The spontaneous phasic contractions and GCs were not affected by inflammation, but the response to ACh was suppressed in DSS-treated rats and in HLA-B27 rats. H2O2production was increased in the muscularis of the inflamed colon. Incubation of colonic muscle strips with H2O2suppressed the spontaneous phasic contractions and concentration and time dependently reduced the response to ACh; in the middle colon, it also increased the frequency of GCs. We conclude that H2O2mimics the suppression of the contractile response to ACh in inflammation. H2O2also selectively suppresses phasic contractions and increases the frequency of GCs, as found previously in inflamed dog and human colons.


2015 ◽  
Vol 813-814 ◽  
pp. 185-189
Author(s):  
C. Ganesan ◽  
Philip Saratha Joanna ◽  
A. Rajaraman ◽  
Dalbir Singh

This study presents the details of experimental and analytical investigations on three different types of composites on their progress to failure under varied type of loadings. The composites are glass/epoxy-GFRP, Kevlar/epoxy-KFRP and Carbon/epoxy-CFRP composites. A series of experiments were carried out to find the variation in mechanical properties in all composites due to displacement controlled tests with different displacement rates such as 0.5mm/min, 1.0 mm/min and 1.5mm/min. The experimental results for CFRP, GFRP and KFRP under three different zones of response viz., stage I- response upto design load-DL, stage II-later from design load to ultimate load-UL followed by Stage II-response upto failure load-FL were discussed. Comparisons of relative performance under different rates and types of damage occurred are discussed from strength, stiffness and energy points of view.


2020 ◽  
Vol 10 (4) ◽  
pp. 254-261
Author(s):  
S. V. Topolyanskaya

Modern concepts about the role of connective tissue growth factor in various physiological and pathological processes are described in the review. Connective tissue growth factor regulates a variety of cellular functions, including proliferation, migration, adhesion, differentiation and synthesis of extracellular matrix proteins in cells of different types. This factor is also involved in more complex biological processes of angiogenesis, chondrogenesis, wound healing, fibrosis and oncogenesis. Increased expression of connective tissue growth factor is observed in different cardiovascular and oncological diseases. Potential role of this growth factor in regulation of cellular senescence and aging processes is also discussed.


Biomolecules ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 12
Author(s):  
Zakaria Mougin ◽  
Julia Huguet Herrero ◽  
Catherine Boileau ◽  
Carine Le Goff

Extracellular matrix (ECM) in the vascular wall is a highly dynamic structure composed of a set of different molecules such as elastins, collagens, fibronectin (Fn), laminins, proteoglycans, and polysaccharides. ECM undergoes remodeling processes to regulate vascular smooth muscle and endothelial cells’ proliferation, differentiation, and adhesion. Abnormalities affecting the ECM can lead to alteration in cellular behavior and from this, this can conduce to the development of pathologies. Metalloproteases play a key role in maintaining the homeostasis of ECM by mediating the cleavage of different ECM components. There are different types of metalloproteases: matrix metalloproteinases (MMPs), disintegrin and metalloproteinases (ADAMs), and ADAMs with thrombospondin motifs (ADAMTSs). ADAMTSs have been found to participate in cardiovascular physiology and diseases and specifically in aortic aneurysms. This review aims to decipher the potential role of ADAMTS proteins in the physiopathologic development of Thoracic Aortic Aneurysms (TAA) and Abdominal Aortic Aneurysms (AAA). This review will focus on what is known on the ADAMTS family involved in human aneurysms from human tissues to mouse models. The recent findings on THSD4 (encoding ADAMTSL6) mutations in TAA give a new insight on the involvement of the ADAMTS family in TAA.


2019 ◽  
pp. 181-213
Author(s):  
Elizabeth Fisher ◽  
Bettina Lange ◽  
Eloise Scotford

Courts play an important role in environmental law. Among other things, they uphold the rule of law and adjudicate on the legal disputes that inevitably arise. This chapter explores the role of courts in environmental law. It outlines why courts are understood to be important in environmental law, what courts are, the different types of courts relevant to UK and EU environmental law, the importance of access to justice, and the actual and potential role of specialist environmental courts. Overall, what is apparent from this chapter is not only that the role of courts is an important one, but that it is also complex.


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