Substance dependence, family history of alcohol dependence and neuropsychological functioning in adolescence

Addiction ◽  
2000 ◽  
Vol 95 (7) ◽  
pp. 1043-1053 ◽  
Author(s):  
Susan F. Tapert ◽  
Sandra A. Brown
Keyword(s):  
Family History ◽  
Alcohol Dependence ◽  
Substance Dependence ◽  
Neuropsychological Functioning ◽  
History Of

scholarly journals Substance Use Disorders in Men Presenting to a Psychosexual Clinic

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Ravi Philip Rajkumar
Keyword(s):  
Substance Use ◽  
Family History ◽  
Sexual Dysfunction ◽  
Substance Use Disorders ◽  
Substance Dependence ◽  
Causal Relation ◽  
Alcohol Use Disorders ◽  
Community Based ◽  
History Of ◽  
A Current

Introduction. Substance use disorders (SUDs) are commonly associated with a variety of psychiatric disorders. Community-based studies have found a significant association between SUDs and sexual dysfunction in men, with a possible causal relation in the case of nicotine. Methods. The case records of 105 men presenting to a clinic for patients with psychosexual disorders were reviewed. Men with and without comorbid SUDs were compared in terms of demographic, clinical, and familial variables. Results. 25 of the 105 men (23.8%) had a lifetime diagnosis of SUD, and 19 (18.1%) had a current SUD. The commonest substances involved were nicotine (n = 21, 20%) and alcohol (n = 9, 9.5%). Men with comorbid SUDs were more likely to report a family history of substance dependence, particularly alcoholism. Single men with SUDs were more likely to have a comorbid mood disorder. Conclusion. SUDs, particularly nicotine and alcohol use disorders, are common comorbidities in patients with psychosexual disorders. Identifying and treating these disorders in this population are important aspects of management.

Family History of Alcohol Dependence in Asian Americans

2003 ◽  
Vol 35 (3) ◽  
pp. 375-377 ◽  
Author(s):  
Nicole C. Ebberhart ◽  
Susan E. Luczak ◽  
Nancy Avanecy ◽  
Tamara L. Wall
Keyword(s):  
Family History ◽  
Alcohol Dependence ◽  
Asian Americans ◽  
History Of

Family history of alcohol dependence modulates functional neurophysiology in mood/anxiety disorders

2012 ◽  
Vol 43 (7) ◽  
pp. 1487-1497 ◽  
Author(s):  
Z. Sjoerds ◽  
M.-J. van Tol ◽  
W. van den Brink ◽  
N. J. A. van der Wee ◽  
A. Aleman ◽  
...  
Keyword(s):  
Family History ◽  
Anxiety Disorders ◽  
Alcohol Dependence ◽  
Treatment Success ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen Level ◽  
Task Load ◽  
Mood And Anxiety Disorders ◽  
Increased Risk ◽  
History Of

BackgroundA family history (FH) of alcohol dependence (AD) not only increases the risk for AD, but is also associated with an increased risk for mood and anxiety disorders. However, it is unknown how a FH of AD affects neural substrates in patients with mood and anxiety disorders. In this study we examined the effects of an alcoholic FH on cognitive and emotional functions in these patients using functional magnetic resonance imaging (fMRI).MethodIn a sample of non-alcoholic patients with depressive and/or anxiety disorders from the Netherlands Study of Depression and Anxiety (NESDA) neuroimaging study, patients with a first-degree FH of AD (FH + ; n = 31) were compared with patients without a FH (FH–; n = 77) on performance and brain activation during visuospatial planning and emotional word encoding. Results were compared with those of healthy controls (HCs) without a FH of AD (n = 31).ResultsFH+ patients performed slower during planning with increasing task load, coupled with stronger blood oxygen level-dependent responses in dorsal prefrontal areas compared with FH− patients and HCs. FH was not associated with performance differences during word encoding, but right insula activation during positive word encoding was present in FH+ patients, comparable with HCs, but absent in FH− patients.ConclusionsThis study demonstrates subtle impairments during planning in FH+ compared with FH− patients and HCs, whereas activation during mood-incongruent stimuli in FH+ patients was similar to HCs but not FH− patients, suggesting that the presence of a FH of AD is a useful marker for the neurophysiological profile in mood/anxiety disorders and possible predictor for treatment success.

scholarly journals Visual P3 findings in Mission Indian youth: relationship to family history of alcohol dependence and behavioral problems

2001 ◽  
Vol 105 (1-2) ◽  
pp. 67-78 ◽  
Author(s):  
Cindy L Ehlers ◽  
Tamara L Wall ◽  
Consuelo Garcia-Andrade ◽  
Evelyn Phillips
Keyword(s):  
Family History ◽  
Alcohol Dependence ◽  
Behavioral Problems ◽  
History Of

scholarly journals Interrelationship between family history of alcoholism and generational status in the prediction of alcohol dependence in US Hispanics

2016 ◽  
Vol 47 (1) ◽  
pp. 137-147 ◽  
Author(s):  
K. G. Chartier ◽  
N. S. Thomas ◽  
K. S. Kendler
Keyword(s):  
United States ◽  
Family History ◽  
Alcohol Dependence ◽  
Interaction Effect ◽  
The United States ◽  
Generational Status ◽  
History Of ◽  
Familial Alcoholism ◽  
Successive Generations ◽  
The Relationship

BackgroundBoth a family history of alcoholism and migration-related factors like US v. foreign nativity increase the risk for developing alcohol use disorders in Hispanic Americans. For this study, we integrated these two lines of research to test whether the relationship between familial alcoholism and alcohol dependence changes with successive generations in the United States.MethodData were from the waves 1 and 2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Subjects self-identified Hispanic ethnicity (N = 4122; n = 1784 first, n = 1169 second, and n = 1169 third or later generation) and reported ever consuming ⩾12 drinks in a 1-year period. A family history of alcoholism was assessed in first- and second-degree relatives. Analyses predicting the number of alcohol dependence symptoms were path models.ResultsAlcohol dependence symptoms were associated with a stronger family history of alcoholism and later generational status. There was a significant interaction effect between familial alcoholism and generational status; the relationship of familial alcoholism with alcohol dependence symptoms increased significantly with successive generations in the United States, more strongly in women than men. Acculturation partially mediated the interaction effect between familial alcoholism and generational status on alcohol dependence, although not in the expected direction.ConclusionsFamilial alcoholism interacted with generational status in predicting alcohol dependence symptoms in US Hispanic drinkers. This relationship suggests that heritability for alcoholism is influenced by a higher-order environmental factor, likely characterized by a relaxing of social restrictions on drinking.

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