scholarly journals Human lung cancer cell lines express cell membrane complement inhibitory proteins and are extremely resistant to complement‐mediated lysis; a comparison with normal human respiratory epithelium in vitro , and an insight into mechanism(s) of resistance

1998 ◽  
Vol 113 (2) ◽  
pp. 173-182 ◽  
Author(s):  
Varsano ◽  
Rashkovsky ◽  
Shapiro ◽  
Ophir ◽  
Mark‐Bentankur
1996 ◽  
Vol 14 (4) ◽  
pp. 351-357 ◽  
Author(s):  
Xin-Hai Pei ◽  
Yoichi Nakanishi ◽  
Koichi Takayama ◽  
Jun Yatsunami ◽  
Feng Bai ◽  
...  

2020 ◽  
Vol 5 (2) ◽  
pp. 164-170
Author(s):  
Deepak P. Kardile ◽  
Mrunal K. Shirsat

In the present study, dihydrobenzimidazole thiopyranooxazinone derivatives were efficiently synthesized, which were further characterized and authenticated by means of TLC and different spectral analysis such as IR and 1H NMR. The synthesized compounds DPK2d2 to DPK2d8 were screened for their in vitro antimicrobial, antitubercular and anticancer activities. The results showed that the titled compounds DPK3d1, DPK3d2 and DPK3d4 exhibited potent antimicrobial activity, shows a broadspectrum activity against Bacillus subtilis, Escherichia coli (antibacterial) and Aspergillus niger (antifungal) as compared to ciprofloxacin and fluconazole, respectively. Compounds DPK3d1, DPK3d3 and DPK3d5 exhibited potent antitubercular activities against Mycobacterium tuberculosis as compared to pyrazinamide, ciprofloxacin and streptomycin. Compounds DPK3d3, DPK3d4 and DPK3d5 showed highly potent cytotoxic activity against human lung cancer cell line (A549) as compared to adriamycin. In silico molecular docking studies shown that all the ligands highest binding affinity range -6.7 to -8.7 for selected 1CB4 PDB of superoxide dismutase, which recognized that ligands having antioxidant activity.


2010 ◽  
Vol 67 (3) ◽  
pp. 637-646 ◽  
Author(s):  
Hua Cheng ◽  
She-Juan An ◽  
Xu-Chao Zhang ◽  
Song Dong ◽  
Yi-Fang Zhang ◽  
...  

2014 ◽  
Vol 67 (1) ◽  
pp. 156-166 ◽  
Author(s):  
Syed Rakashanda ◽  
Asif Khurshid Qazi ◽  
Rabiya Majeed ◽  
Syed Mubashir Andrabi ◽  
Abid Hamid ◽  
...  

2013 ◽  
Vol 2 (1) ◽  
pp. 16 ◽  
Author(s):  
Ping Wang ◽  
Zhenhe Suo ◽  
Mengyu Wang ◽  
Hanne K Høifødt ◽  
Øystein Fodstad ◽  
...  

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