Age-Related Changes in Rat Optic Nerve: Morphological Studies

2003 ◽  
Vol 32 (1) ◽  
pp. 12-16 ◽  
Author(s):  
C. Cavallotti ◽  
D. Cavallotti ◽  
N. Pescosolido ◽  
E. Pacella
2002 ◽  
Vol 37 (7) ◽  
pp. 389-394 ◽  
Author(s):  
Carlo Cavallotti ◽  
Elena Pacella ◽  
Nicola Pescosolido ◽  
Francesca Maria Tranquilli-Leali ◽  
Janos Feher

Author(s):  
Grigory Andreyevich Shishanov

Morphometric studies are fundamental in the domestication of new fish species. Despite the obvious dependence of the morphological parameters of fish on habitat conditions, they are currently used as the main criteria for the approval of breeding achievements, and a measure of the processes of domestication and selection. In this regard, we have begun work to study the variability of morphological characters in the process of domestication of stellate sturgeon (Asipenser stellatus, Pall) in a closed water supply. Researched sturgeon of Volga origin grown from caviar in artificial conditions in a closed water supply installation. At the first stage, 25 morphological parameters of stellate sturgeon underyearlings were studied. At the second stage, six years later, morphological studies were repeated in the same group of fish. Comparison of the average values of the indicators indicates the following trends in their change with the age of the fish: the relative length and height of the head, the rostrum (rr), and the diameter of the eye, the width of the mouth and the width of the break of the lower lip decrease; the indicators of the distance between the fins relative to the end of the snout and between themselves increase, the smallest and largest body height. At the same time, the most significant significant differences between underyearlings and six-year-olds were found in body height and head length. Similar changes are observed with age in most fish, including sturgeon. They are associated with the development of swimming muscles, physiological changes and demonstrate the expected biological age-related changes. The presented data on age-related changes in morphological parameters show the erroneousness of using sturgeon underyearlings as a control group for assessing uniformity and stability for distinctness.


1989 ◽  
Vol 107 (5) ◽  
pp. 476-484 ◽  
Author(s):  
M. Rosario Hernandez ◽  
Xing Xing Luo ◽  
Wieslawa Andrzejewska ◽  
Arthur H. Neufeld

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Matt Trinh ◽  
Vincent Khou ◽  
Barbara Zangerl ◽  
Michael Kalloniatis ◽  
Lisa Nivison-Smith

AbstractCurrent descriptions of retinal thickness across normal age cohorts are mostly limited to global analyses, thus overlooking spatial variation across the retina and limiting spatial analyses of retinal and optic nerve disease. This retrospective cross-sectional study uses location-specific cluster analysis of 8 × 8 macular average grid-wise thicknesses to quantify topographical patterns and rates of normal, age-related changes in all individual retinal layers of 253 eyes of 253 participants across various age cohorts (n = 23–69 eyes per decade). Most retinal layers had concentric spatial cluster patterns except the retinal nerve fibre layer (RNFL) which displayed a nasal, asymmetric radial pattern. Age-related thickness decline mostly occurred after the late 4th decade, described by quadratic regression models. The ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), and outer nuclear layer + Henle’s fibre layer (ONL+HFL) were significantly associated with age (p < 0.0001 to < 0.05), demonstrating similar rates of thickness decline (mean pooled slope =  − 0.07 µm/year), while the IS/OS had lesser mean pooled thickness slopes for all clusters (− 0.04 µm/year). The RNFL, OPL, and RPE exhibited no significant age-related thickness change, and the RNFL were significantly associated with sex. Analysis using spatial clusters compared to the ETDRS sectors revealed more extensive spatial definition and less variability in the former method. These spatially defined, clustered normative data and age-correction functions provide an accessible method of retinal thickness analysis with more spatial detail and less variability than the ETDRS sectors, potentially aiding the diagnosis and monitoring of retinal and optic nerve disease.


The article presents the results of morphological studies of cross-sectional area growth in the first and second phalanges, their bone-marrow cavities and compacted tissue in the postnatal ontogenesis of Ro-manov sheep. As the material for this work we used the I and II phalanges, taken from the left thoracic limb of opposite gender twins at birth, as well as at 3,6,9,12 months of age and in adults 3–4 years of age. To identify phalanges development patterns we used classical morphological methods of research: we determined the growth rate (“K”), age-related changes in the cross-sectional area of the first and second fingers, their bone-marrow cavities and compacts in the studied age periods (M ± m) and in relation to the same indicator in adult sheep in %.. The received digital material was subjected to static processing. It was established that, due to the periosteal growth of bone tissue, cross-sectional area of the I and II phalanges increases all the time, reaching the definitive value by 12 months at the I phalanx, and in the II phalanx it occurs somewhat later. More accelerated periosteal growth is observed in both phalanges in the first three months of lambs’ life. Due to the processes of bone resorption on the side of endosteum, the same thing happens with the cross section of bone marrow cavities, they only reach the definitive state a little earlier, that was noted in the cross section of the bones. In general, the intensity of periosteal growth and resorption processes occur more quickly in I phalanges compared with II.


Sign in / Sign up

Export Citation Format

Share Document