scholarly journals Influence of polymorphism of the kappa-casein gene of cows on the development of calves in the early postnatal period

2021 ◽  
Vol 262 ◽  
pp. 02002
Author(s):  
Olga Polozyuk ◽  
Margarita Zabelina ◽  
Tatiana Preobrazhenskaya ◽  
Igor Tyurin ◽  
Elena Lakota

The authors found that the density of colostrum in cows with a homozygous genotype for the B allele of the kappa-casein gene was higher compared to the homozygous genotype for the A allele and had a greater amount of immunoglobulins by 29.5 mg/l, respectively. The formation of high colostral immunity in calves obtained from cows of mothers of genotypes AB and BB prevented the occurrence of diseases of the gastrointestinal tract, and in calves obtained from mothers of genotype AA genotype kappa-casein with a reduced amount of immunoglobulins in colostrum, it led to the development of diarrhea in 12% of newborn calves. The dynamics of the live weight of calves obtained from cows of mothers with the AA genotype of the kappa-casein gene, during the first 30 days of life, was 6.34 and 4.78 kg lower than in young cows with the BB and AB genotypes of the kappa-casein gene. At the age of one month, the leukocyte content in calves obtained from cows from mothers with a homozygous genotype for allele A of the kappa-casein gene was less by 10.8 and 16.2%, and hemoglobin by 10.5 and 10.7%.

10.12737/7744 ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. 124-127
Author(s):  
Самоделкин ◽  
Aleksandr Samodelkin ◽  
Еремин ◽  
Sergey Eremin

There was studied the distribution of postpartum pathology of cows and disease of calves in early postnatal period in conditions of Nizhny Novgorod region. It was established, that the new tissue drug "bio-tec" has positive influence on reproductive function, safety and live weight gain of calves. The postpartum pathology of cows gained wide spread among nizhnynovgorod farms up to 80%, e.g. Endometritis and subinvolution of uterus 37,4 and 23,9 respectively. By clinical examination of newborn calves it was established, that in the first month of life 50,3% fall ill with gastrointestinal diseases of various etiologies. The die-off of calves reached 29%. Using "bio-tec" drug to dry cows decreased the percentage of postpartum pathology by 35% and reduced the time of involution of uterus for 11,2 days; the service period reduced by 21,2 days and the diseases of newborn calves was twice less, that increased the energy of growth and in 16 month age heifers went over animals of the control group by 10%, that allowed their earlier use for reproduction. So, the results of conducted research showed, that twice a day injection of tissue drug "bio-tec" to dry cows in 10ml dose 60-55 and 40-35 days to calving contributes reducing of obstetric pathology. Subsequent use to calves in 4ml dose in 5-8 days age increases the safety of calves and positively influences the live weight gain, that in fact gives abilities of more effective cattle breeding.


2018 ◽  
Vol 2018 (6) ◽  
pp. 20-24 ◽  
Author(s):  
Юрий Федоров ◽  
Yuriy Fedorov ◽  
Валентина Клюкина ◽  
Valentina Klyukina ◽  
Олеся Богомолова ◽  
...  

Transmission of immunoglobulins (Ig) from mother to newborns, classified as passive transmission of immunity, is a critical factor in protecting newborns from infectious diseases. Syndesmochorial structure of the cows placenta prevents the transfer of Ig from the mother to the fetus, so calves are born agammaglobulinemic, that is, without their own Ig, which they receive when consuming colostrum. Obtaining colostrum with high Ig content is the main factor of growth, development and protection of calves in the early postnatal period against pathogens in the environment. Universal media passive immunity is IgG. Violation of passive transfer of Ig leads to an increase in sickness rate and mortality and is considered as an important economic problem for industrial farming. The review discusses the current understanding of the properties, function and importance of cow colostrum in the formation of the immune status of newborn calves and their resistance to disease in the early postnatal period.


2021 ◽  
Vol 935 (1) ◽  
pp. 012044
Author(s):  
V G Semenov ◽  
E S Matveeva ◽  
D E Biryukova ◽  
A N Maykotov ◽  
S G Kondruchina ◽  
...  

Abstract A scientific and practical substantiation of the need for the timely formation of colostral immunity in calves to create nonspecific protection of the body and adaptation of newborns to new environmental conditions is given, which is the most important problem of modern veterinary science and practice. Colostral immunity is immunity that develops in newborns due to colostral immunoglobulins during the first 24-36 hours of life. For some newborn farm animals (horses, ruminants and pigs), antibodies are transmitted to offspring only through colostrum in the early postnatal period. In order to increase the nonspecific defenses of the body of mothers cows, the formation of colostral immunity in newborn calves and the realization of the biological resource potential of the body, immunostimulants were used, developed by scientists of the Chuvash State Agrarian University: Prevention-N-B-S and Salus-PE.


2021 ◽  
pp. 65-67
Author(s):  
Olga Nikolaevna Polozyuk ◽  
Tatyana Ivanovna Lapina

It was found that the use of a prebiotic based on blue-green microalgae in pigs in the early postnatal period of development improved their reproductive qualities. The weight of the nest at birth and the live weight of piglets at weaning in the first litter gilts of the control group was 9.5 and 23.7% less than in the sows of the experimental group. The milk production of the ewes in the experimental group was 8.4 kg higher than in the control group. As they grew and were able to use additional feeding, the piglets in the experimental group overtook their peers and by weaning had a live weight of 14.3 kg (23.7%) more than in the control group. The safety of piglets obtained from the first litter gilts of the experimental group during the weaning period (32 days) was 5.3% more than the control.


2019 ◽  
pp. 14-16
Author(s):  
O.P. YUDINA ◽  
M.YU. BORISOV ◽  
A.S. DELIAN

Генотипирование 51 быка голштинской породы немецкой и голландской селекции по гену каппа-казеина показало, что наибольшая частота встречаемости желательного аллеля CSN3В зафиксирована у быков-производителей голландской селекции (21,43%), что на 4,4% выше встречаемости его у немецких быков. Наиболее желательный генотип CSN3ВВ каппа-казеина в изучаемом поголовье не выявлен. Частота встречаемости генотипа CSN3АВ гена каппа-казеина у быков из Нидерландов составила 42,86%, или на 8,8% выше, чем у немецких быков. Изучено влияние быков голштинской породы разного происхождения, различающихся по генотипам гена каппа-казеина на динамику живой массы их дочерей от рождения до возраста 3-й лактации. Установлено, что от быков с генотипом CSN3АВ как немецкой, так и голландской селекции рождались телочки с большей живой массой; при этом дочери быков с генотипом CSN3АА лучше росли в период от 6 до 18 мес независимо от происхождения. Живая масса дочерей быков немецкой селекции при первом оплодотворении была одинаковой, в голландской селекции преимущество на 20,4 кг имели дочери быков с генотипом CSN3АВ гена каппа-казеина. Максимальную живую массу к возрасту 1-й лактации имели дочери быков немецкой селекции с генотипом CSN3АВ (521 кг), дочери быков голландской селекции с генотипом CSN3АА (520,5 кг). У коров 3-й лактации наивысшая живая масса была у обладателей генотипа CSN3АВ (568,5 кг и 581,3 кг), в группах немецкой и голландской селекции, соответственно.Genotyping of 51 Holstein bulls of German and Dutch breeding on the Kappa-casein gene showed that the highest frequency of occurrence of the desirable allele CSN3B was recorded in Dutch breeding bulls (21.43%), which is 4.4% higher than its occurrence in German bulls. Most desirable CSN3ВВ genotype of Kappa-casein in the studied population were not identified. Frequency of genotype CSN3АВ of the gene Kappa-casein bulls from the Netherlands amounted to 42,86%, or 8.8% higher than the German bulls. Influence of the bulls of golshtinsky breed of different origin differing on gene genotypes of a Kappa-casein on dynamics of live mass of their female calves from the birth to the age of the 3rd lactation is studied. It is established that heifers with higher live weight were born from the bulls with genotype CSN3АВ both the German and Dutch breeding; moreover, the female calves of bulls with genotype CSN3АА grow better in the period from 6 to 18 months regardless of origin. The live weight of female calves of bulls of the German selection at the first insemination was the same, in the Dutch selection female calves of bulls with genotype CSN3АВ of the gene Kappa-casein had advantage of 20.4 kg. The maximum live weight by the age of the 1st lactation had female calves of bulls of German selection with genotype CSN3AV — 521 kg, female calves of bulls of Dutch selection-with genotype CSN3AA (520.5) kg. — with a genotype of CSN3AA (520.5) kg had the maximum live weight. The 3rd lactation cows had the highest live weight with CSN3AB genotype — 568.5 kg and 581.3 kg, in groups of the German and Dutch selection, respectively.


Reproduction ◽  
1993 ◽  
Vol 97 (1) ◽  
pp. 13-20 ◽  
Author(s):  
L. Pinilla ◽  
E. Trimino ◽  
P. Garnelo ◽  
C. Bellido ◽  
R. Aguilar ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document