Post-traumatic massive hand lymphedema fully cured by vascularized lymph node flap transfer

Post-traumatic localized hand lymphedema is a rare situation and its diagnosis may be difficult, causing lack of care leading to failure of care. Our case study is of two young women with massive post-traumatic hand lymphedema who were treated for algodystrophy for 2 years, and whose bandages and physiotherapy were unsuccessful. Major social and psychological consequences due to difficulty with diagnosis and management resulting in inappropriate tests and therapeutic treatment were prescribed due to these issues. Noncontrast magnetic resonance lymphography revealed complete lymphatic vessel blockage in the hand and wrist. A vascularized lymph node flap harvested at the groin level was transferred to the elbow level 1 month after local dermolipectomy. These procedures resulted in the restoration of lymphatic flow. Both patients were definitely cured, and they returned to normal life within 6 months after surgery. Lymph node flap transfer associated with dermolipectomy may cure massive localized lymphedema in selected cases.

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Faculty Opinions recommendation of T lymphocytes negatively regulate lymph node lymphatic vessel formation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8095960.8920055 ◽

2011 ◽

Author(s):

Jens V Stein

Keyword(s):

Lymph Node ◽

T Lymphocytes ◽

Lymphatic Vessel ◽

Vessel Formation

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Life Perspective and Social Health in Acid Burn Victims (Preprint)

10.2196/preprints.12021 ◽

2018 ◽

Author(s):

Unsa Athar ◽

Saad-Ur Rahman ◽

Hafeez Ur Rehman ◽

Waqar Ahmed ◽

Shaarif Kaleem

Keyword(s):

Traumatic Stress ◽

Social Health ◽

Post Traumatic Stress ◽

Young Sister ◽

Burn Victims ◽

Negative Change ◽

Depth Interview ◽

Post Traumatic ◽

Socially Isolated

UNSTRUCTURED ABSTRACT: Life perspective, behavior, feelings and social health changes in a victim of acid burn attack. Objective: To determine the changes and life perspective and social health in acid burn victims. Study Design: Case report study Study Duration and Place: The study was conducted in 6-month duration in the department of Plastic Surgery, Mayo Hospital, Lahore. Methodology: This is a case study of unmarried woman and her young sister, who suffered acid burn violence. Two sessions were held. First was to develop the rapport while the second was an in depth interview. Data were collected using a question guide, and was analyzed using Grounded theory. Results: The patient suffered from structural and functional loss after the incident and also suffered from post-traumatic stress disorder. She feels socially stigmatized and isolated. Her life perspective has changed. She received informal social support but required formal social rehabilitation. Lack of legislation has made her feel hopeless because she has not received justice. Conclusion: Our patient is a 20 years old woman, who suffered from an acid throwing attack from a neighbor. Her young sister who was sleeping beside suffered too. The incident has led to a negative change in her behavior, feelings, and life perspective. She is socially isolated. She has had informal support but she needs better formal support. The need of the hour is improvement of public sector rehabilitation for acid burn victims and proper legislation. Keywords: Acid burn victims. Life perspective, social health

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Edemas of the face and lymphoscintigraphic examination

Scientific Reports ◽

10.1038/s41598-021-85835-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Pierre Bourgeois ◽

E. Peters ◽

A. Van Mieghem ◽

A. Vrancken ◽

G. Giacalone ◽

...

Keyword(s):

Head And Neck Cancer ◽

Lymph Node ◽

Cervical Lymph Node ◽

Cervical Vertebra ◽

Lymphatic Drainage ◽

The Face ◽

Facial Edema ◽

Post Traumatic ◽

Left And Right ◽

Lymphatic Pathways

AbstractFacial edemas not secondary to surgery and/or radiotherapy for head and neck cancer are relatively uncommon. Our aim is to report a retrospective analysis of the lymphoscintigraphic and SPECT-CT investigations obtained in patients with such facial edema. Retrospective review of exams (planar imagings in all and with SPECT-CT in 5) obtained after the subcutaneous injection of 99mTc HSA Nanosized colloids between the eyebrows in five men and seven women. Four main lymphatic pathways were identified on sequential planar imagings: para-nasal left and right and supra- ocular left and right. For eleven patients, the absence of visualization of lymphatic drainage and/or their delayed appearance correlated well with the localisation of the edematous areas. In two patients with post-traumatic and post- surgical edemas, SPECT-CT showed one deep left sided cervical lymph node (LN) in front of the first cervical vertebra. This lymphoscintigraphic approach represents a simple and valuable way to assess the lymphatic drainage pathways of the face and to establish the diagnosis of facial lymphedema.

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ctDNA Clearance and Radiographic Resolution of Disease in Response to Dual Checkpoint Inhibition in Metastatic Microsatellite Stable Colorectal Cancer with a High Tumor Mutation Burden

Case Reports in Oncology ◽

10.1159/000516190 ◽

2021 ◽

pp. 849-853

Author(s):

Charles J. Schneider ◽

Michael Krainock ◽

Allyson Koyen Malashevich ◽

Meenakshi Malhotra ◽

Perry Olshan ◽

...

Keyword(s):

Colorectal Cancer ◽

Lymph Node ◽

Ct Scan ◽

Circulating Tumor Dna ◽

Therapeutic Benefit ◽

Tumor Mutation Burden ◽

Early Treatment Response ◽

Mutation Burden ◽

Disease Present

Immunotherapy (IO) has increasingly been demonstrated to provide therapeutic benefit to patients with metastatic colorectal cancer (mCRC). However, only a subset of mCRC tumors respond to IO. Monitoring response with tumor biomarkers like carcinoembryonic antigen (CEA) has been challenging in patients with microsatellite stable (MSS) mCRC due to low expression of CEA (CEA/lo). Noninvasive blood-based biomarkers such as circulating tumor DNA (ctDNA) can inform early treatment response and augment radiographic monitoring. We describe a case study of a patient with chemotherapy-refractory CEA/lo MSS mCRC, with metastatic disease present in a cardiophrenic lymph node. The patient was given 2 cycles of combination IO (ipilimumab/nivolumab). Response was monitored by ctDNA using a multiplex PCR next-generation sequencing assay, CEA, and CT scan. After IO administration, ctDNA levels rapidly declined, becoming undetectable. This was concurrent with radiographic resolution of the lymph node metastasis. Serial monitoring of CEA during this same period was uninformative, with no significant changes observed. Significant decline in ctDNA identified metastatic response to IO in a patient with CEA/lo, MSS mCRC and was concurrently validated by CT scan. This case study provides evidence that ctDNA can be used as a prospective surrogate for radiographic tumor response.

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Botulinum toxin in the treatment of post-traumatic headache – case study

Neurologia i Neurochirurgia Polska ◽

10.5114/ninp.2012.32109 ◽

2012 ◽

Vol 46 (6) ◽

pp. 591-594 ◽

Cited By ~ 7

Author(s):

Marcela Lippert-Grüner

Keyword(s):

Botulinum Toxin ◽

Post Traumatic

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The impact of spousal violence on the children: A pastoral care approach

HTS Teologiese Studies / Theological Studies ◽

10.4102/hts.v70i2.2044 ◽

2014 ◽

Vol 70 (2) ◽

Cited By ~ 1

Author(s):

Luvuyo G. Sifo ◽

Maake J. Masango

Keyword(s):

Pastoral Care ◽

Post Traumatic Stress Disorder ◽

Traumatic Stress ◽

Spousal Violence ◽

Post Traumatic Stress ◽

Case Scenario ◽

Care Approach ◽

Post Traumatic ◽

The Impact

This article investigates the impact of spousal violence on children. Spousal violence in the home affects children negatively and its impact goes beyond their childhood years into adulthood. Some children become dysfunctional in life as a result of their exposure to violence between their parents. These children may exhibit symptoms associated with post-traumatic stress disorder (PTSD) later on in life. A case study of a family exposed to violence was undertaken. Findings from this case scenario were measured against existing literature. A pastoral care method of responding to the victims is proposed in order for them to be healed.

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Enhancing Girls’ Physical Activity and Self-Image: A Case Study of the GoGirlGo Program

Women in Sport and Physical Activity Journal ◽

10.1123/wspaj.18.1.28 ◽

2009 ◽

Vol 18 (1) ◽

pp. 28-41 ◽

Cited By ~ 3

Author(s):

Stacy Warner ◽

Marlene A. Dixon ◽

Christyn Schumann

Keyword(s):

Physical Activity ◽

Young Women ◽

Sports Participation ◽

Qualitative Investigation ◽

Women's Sports ◽

Delivery Method ◽

Developmental Programs ◽

Self Image ◽

Women’S Sports

Physical activity and sport developmental programs have demonstrated some success at providing valuable resources for young women as they navigate their teen years, yet these programs are not always intentional and/or accessible (Cadwallader, 2001; Petitpas, Cornelius, Van Raalte, & Jones, 2004; Tucker Center, 2007). One such program developed by the Women’s Sports Foundation is GoGirlGo. The curriculum, which combines sports participation with education, focuses on reducing and preventing unhealthy behaviors and on providing valuable connections and resources for girls. Using the theory of developmental intentionality, this qualitative investigation examined the efficacy of GoGirlGo in a five day long sport camp setting. This condensed delivery method is not addressed or recommended in the literature, yet the results of this investigation reveal that this delivery method is effective and could broaden the accessibility of the program.

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