167 Seasonal Variation in Vitamin D Levels Among Dialysis Patients

Vitamin D deficiency, which is a global health problem, may result in numerous diseases, such as rickets in children and osteoporosis and osteomalacia in adults. The occurrence of the above-mentioned disorders is promoted by the wintertime and higher latitudes. The aim of the study was to compare the concentrations of vitamin D (25-OH) in hospitalized patients and outpatients in different seasons of the year (summer and winter), as well as in dialysis patients in December and May. The Roche test for the quantitativedetermination of total vitamin D (25-OH) was used in the study. The range from 30 to 80 ng/ml was accepted as the optimum concentration. In hospitalized patients and outpatients, both in summer and winter mean concentration of vitamin D (25-OH) reached the values below 30 ng/ml in over 80% of the patients. Only in the hospitalized patient group mean concentration of vitamin D (25-OH) in the summer was significantly higher than in the winter (p=0.0016). In the dialysis patients mean concentration of vitamin (25-OH) in May was significantly higher than in December (p=0.0085) and the percent of the results below 30 ng/ml amounted to 96.39% in December and 77.27% in May. In conclusion, the 25(OH)D concentrations in the whole population under study are lower than those recommended and undergo periodical seasonal changes in hospitalized patients.

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Reversed Seasonal Variation in Maternal Vitamin D Levels in Southern Louisiana

Clinical Pediatrics ◽

10.1177/0009922812444599 ◽

2012 ◽

Vol 51 (8) ◽

pp. 718-722 ◽

Cited By ~ 3

Author(s):

Mariam Gangat ◽

Tulasi Ponnapakkam ◽

Elease Bradford ◽

Ranjitha Katikaneni ◽

Robert Gensure

Keyword(s):

Vitamin D ◽

Seasonal Variation ◽

Maternal Vitamin ◽

Vitamin D Levels ◽

Southern Louisiana

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Vitamin D Status and Its Determinants in a Paediatric Population in Norway

Nutrients ◽

10.3390/nu12051385 ◽

2020 ◽

Vol 12 (5) ◽

pp. 1385

Author(s):

Mads N Holten-Andersen ◽

Johanne Haugen ◽

Ingvild Oma ◽

Tor A Strand

Keyword(s):

Vitamin D ◽

Seasonal Variation ◽

Children And Adolescents ◽

Parental Education ◽

Sun Exposure ◽

Late Summer ◽

Paediatric Population ◽

Vitamin D Supplementation ◽

Healthy Children ◽

Vitamin D Levels

Recommendations for sufficient vitamin D intake in children were recently revised in Norway. However, optimal levels of vitamin D are still debated and knowledge on supplementation and vitamin D levels in healthy children in Norway is scarce. Therefore, we measured the plasma-concentration of 25-hydroxyvitamin D (25(OH)D) in children and adolescents attending the outpatient paediatric clinics in Innlandet Hospital Trust, Norway during two consecutive years (2015–2017). We recruited 301 children and adolescents aged 5 months to 18 years (mean 7.8, SD 4.4 years) for the study and obtained sample material for 25(OH)D measurements from 295 (98%). Information on diet, vitamin D supplementation, sun exposure, ethnicity, parental education and general health was collected by questionnaire. 25(OH)D levels were analysed and determinants for 25(OH)D were estimated by linear regression. 1.0% of the children had deficient levels (25(OH)D < 25 nmol/L) and 21.0% had insufficient levels (25–50 nmol/L). 25(OH)D levels ranging from 50 to 75 nmol/L were found among 38.3%, while 39.7% had levels above 75 nmol/L. The mean 25(OH)D level was 70.0 nmol/L (SD 23.4, range 17–142 nmol/L) with a significant seasonal variation with lowest levels in mid-winter and highest in late summer. In addition to seasonal variation independent determinants for 25(OH)D-levels were age of the child, parental ethnicity, vitamin D supplementation and soda consumption. Along with parental ethnicity other than Nordic, age was the strongest determinant of 25(OH)D, with adolescents having the lowest levels.

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