Study on the relationship between serum 25-hydroxyvitamin D levels and vascular calcification in hemodialysis patients with consideration of seasonal variation in vitamin D levels

2012 ◽  
Vol 220 (2) ◽  
pp. 563-568 ◽  
Author(s):  
Jae Hyun Chang ◽  
Han Ro ◽  
Sejoong Kim ◽  
Hyun Hee Lee ◽  
Wookyung Chung ◽  
...  
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Vascular Calcification ◽  
Hemodialysis Patients ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
The Relationship

scholarly journals Relationship Between Level of Serum 25-Hydroxyvitamin D and Risk of Squamous Cell Carcinoma in an Iranian Population

2019 ◽  
pp. 278-282
Author(s):  
Mahboobeh-Sadat Hosseini ◽  
Fereshteh Salarvand ◽  
Amir Houshang Ehsani ◽  
Pedram Noormohammadpour ◽  
Shadi Azizzadeh ◽  
...  
Keyword(s):  
Vitamin D ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Outdoor Environment ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
History Of ◽  
25 Hydroxyvitamin D ◽  
The Relationship

Background: The relationship between vitamin D and skin squamous cell carcinoma (SCC) is not well defined. Objective: To investigate the relationship between vitamin D levels and the incidence of skin SCC for the first time in Iran. Methods and Study Design: In this case-control study, 126 subjects were enrolled (63 in each group) out of referents to Razi Skin Hospital in Tehran in 2014. The risk factors for cancer gathered by self-reported questionnaires and blood samples were obtained to measure the level of 25-hydroxyvitamin D. Multivariate logistic regression was used to neutralize the effect of confounding factors. Results: Cases of SCC were more likely to be in men, older than 49 years and working in an outdoor environment, and with longtime exposure to sunlight and a personal history of skin cancers. Family history of skin cancer and of cigarette smoking were not significantly related to SCC. In the SCC and control groups, 69.8% and 31.7%, respectively, had sufficient levels of vitamin D (P < 0.001). Mean level of 25-hydroxyvitamin D was 40.99 ng/mL in the SCC group and 26.34 ng/mL in the control group (P < 0.05). In the unadjusted model, the level of vitamin D as a continuous variable was positively related to SCC risk. In the adjusted model, vitamin D did not independently predict the likelihood of SCC. Conclusion: Vitamin D level and SCC risk are directly related, although not in an independent fashion. Indeed, this relation is severely confounded by exposure to sunlight, which was evidenced by an increased vitamin D level in the people working outside and the higher prevalence of SCC in the same population.

Association between Vitamin D Level and Acne, and Correlation with Disease Severity: A Meta-Analysis

Dermatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Yusuf Hasamoh ◽  
Kunlawat Thadanipon ◽  
Premjit Juntongjin
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Meta Analysis ◽  
Inverse Association ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
Newcastle Ottawa Scale ◽  
25 Hydroxyvitamin D ◽  
The Relationship ◽  
Ottawa Scale

<b><i>Background:</i></b> Vitamin D deficiency is frequently associated with several medical conditions. However, a comprehensive meta-analysis assessing the association between vitamin D level and acne is lacking. <b><i>Objective:</i></b> To determine the relationship between vitamin D level and acne, and to assess the association between vitamin D level and acne severity. <b><i>Methods:</i></b> This meta-analysis was assessed by using the PubMed, EMBASE, Cochrane, and Scopus databases following the PRISMA guidelines. Serum/plasma 25-hydroxyvitamin D (25[OH]D) level, vitamin D deficiency, and the severity association between acne patients and healthy controls (HCs) were evaluated. The quality assessment was performed by using the Newcastle-Ottawa Scale. <b><i>Results:</i></b> Thirteen articles with a total of 1,362 acne patients and 1,081 HCs were included. The circulating 25(OH)D levels were significantly lower in patients with acne than in HCs (pooled MD = –9.02 ng/mL, 95% CI = –13.22 to –4.81, <i>p</i> &#x3c; 0.0001). Vitamin D deficiency was more prevalent in acne patients than in HCs (pooled OR = 2.97, 95% CI = 1.68–5.23, <i>I</i><sup>2</sup> = 72%). Also, vitamin D levels were negatively correlated with acne severity. <b><i>Conclusion:</i></b> This meta-analysis demonstrated the significantly low vitamin D levels in acne patients. Also, there was evidence of an inverse association between vitamin D levels and acne severity. Therefore, vitamin D might be involved in the pathogenesis of acne.

Correlation between vitamin D levels and hard-to-heal wounds: a systematic review

2020 ◽  
Vol 29 (Sup7) ◽  
pp. S24-S30 ◽  
Author(s):  
Karen Smith ◽  
Susan Hewlings
Keyword(s):  
Vitamin D ◽  
Financial Burden ◽  
Vitamin D Supplementation ◽  
Nutritional Deficiencies ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Venous Ulcers ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
The Relationship

Objective: Hard-to-heal wounds are a major biological, psychological, social and financial burden on both individual patients and the broader health system. They are associated with a variety of comorbidities and have a complex aetiology, but are typically associated with nutritional deficiencies, such as low vitamin D levels. This systematic literature review evaluates the current research regarding the connection between inadequate vitamin D status and wound healing. Method: PubMed and EBSCO databases were searched following PRISMA guidelines for primary research studies relating to pressure ulcers, diabetic ulcers or venous ulcers and vitamin D status. Results: A total of 10 studies, involving 2359 participants, met the inclusion criteria. There was a strong correlation between low levels of 25-hydroxyvitamin D and the presence of all three types of hard-to-heal wounds. Conclusion: Research suggests a correlation between low vitamin D levels and hard-to-heal wounds. However, it is not clear if the relationship is causal or only correlational. There is also emerging evidence on the use of vitamin D supplementation for the treatment of hard-to-heal wounds. More research is needed to understand the correlation between vitamin D and hard-to-heal wounds.

Correlation between vitamin D levels and hard-to-heal wounds: a systematic review

2021 ◽  
Vol 30 (Sup6) ◽  
pp. S4-S10
Author(s):  
Karen Smith ◽  
Susan Hewlings
Keyword(s):  
Vitamin D ◽  
Financial Burden ◽  
Vitamin D Supplementation ◽  
Nutritional Deficiencies ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Venous Ulcers ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
The Relationship

Objective: Hard-to-heal wounds are a major biological, psychological, social and financial burden on both individual patients and the broader health system. They are associated with a variety of comorbidities and have a complex aetiology, but are typically associated with nutritional deficiencies, such as low vitamin D levels. This systematic literature review evaluates the current research regarding the connection between inadequate vitamin D status and wound healing. Method: PubMed and EBSCO databases were searched following PRISMA guidelines for primary research studies relating to pressure ulcers, diabetic ulcers or venous ulcers and vitamin D status. Results: A total of 10 studies, involving 2359 participants, met the inclusion criteria. There was a strong correlation between low levels of 25-hydroxyvitamin D and the presence of all three types of hard-to-heal wounds. Conclusion: Research suggests a correlation between low vitamin D levels and hard-to-heal wounds. However, it is not clear if the relationship is causal or only correlational. There is also emerging evidence on the use of vitamin D supplementation for the treatment of hard-to-heal wounds. More research is needed to understand the correlation between vitamin D and hard-to-heal wounds.

scholarly journals Relationship of vitamin D, BMI and BMD in age and gender linked population

2018 ◽  
Vol 4 (3) ◽  
pp. 406
Author(s):  
Ritwik Ganguli ◽  
Priyanka Pahari
Keyword(s):  
Vitamin D ◽  
Vitamin D Insufficiency ◽  
Healthy Individuals ◽  
Mineral Density ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
And Gender ◽  
Relationship Of ◽  
The Relationship

<p class="abstract"><strong>Background:</strong> Vitamin D insufficiency prevalence has been related to low bone mineral density (BMD). However, controversial results have been reported for the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and BMD. This study was done to investigate whether serum 25(OH)D levels were associated with BMD in different age group and sex link population.</p><p class="abstract"><strong>Methods:</strong> This study involved, aged 40-70 yr, who is consecutively selected from KPCMCH, BMD camp. BMD was measured at the lumbar spine and femoral neck. The correlation between serum 25(OH)D levels and BMD was investigated.<strong></strong></p><p class="abstract"><strong>Results:</strong> Vitamin D levels for healthy and patients individuals at hospital. The age of 40 healthy subjects ranged from 40 to 70 years with the average of 55.30±10.30 years and body mass index (BMI) ranged from 18 to 37 kg/m<sup>2</sup>, with the of average of 28.90±5.20 kg/m<sup>2</sup>. Comparison between healthy and patients based on BMI and vitamin D level for the overweight BMI healthy individuals was 29.78±9.40 ng/ml, and that of hyperlipidemic patients was 24.47±8.78 ng/ml.</p><p class="abstract"><strong>Conclusions:</strong> In this study, there is significant different between healthy and patients group in vitamin D<sub>3</sub>level.BMD significantly decreased in patients group more elderly.</p>

scholarly journals Evaluation of vitamin D levels and body mass indexes of university employees

2020 ◽  
Vol 19 (2) ◽  
pp. 229-236
Author(s):  
Murat Emrah MAVİŞ ◽  
Çiğdem YILDIRIMMAVİŞ ◽  
İrem ÖZAY ARANCIOĞLU ◽  
Hatice Kübra YILMAZ ◽  
Berrak ERGÜDEN ◽  
...  
Keyword(s):  
Vitamin D ◽  
Body Mass ◽  
Anthropometric Measurement ◽  
University Employees ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
25 Hydroxyvitamin D ◽  
Body Mass Indexes ◽  
The Relationship

Objective: Vitamin D is known to have important effects on human health. The existence of a relationship between obesity and vitamin D levels, which have been shown to cause a number of health problems with various studies, is certain. In this study, the relationship between vitamin D levels and body mass indexes(BMI) of individuals was evaluated. The study is unique for being the only research on literature that carried out with university employees. Materials and methods: Blood samples, anthropometric measurement (BMI) was obtained from 87 volunteer working at Haliç University. The questionnaire form covering the basic questions applied by means of face-to-face method. Quantification of the analytes for 25-hydroxyvitamin-D was carried out using LC-MS/MS. The relationship between 25-hydroxyvitamin-D values and BMI was evaluated with Tukey HSD multiple comparison test. 95% confidence and 80% power sampling were applied to the predictions of a minimum0.50 connection coefficient between 2 quantitative variables.The necessity of 30 cases was determined by using the N = [(Zα+Zβ)/C]2 + 3formula.Considering the losses, the work will be carried out over 80 people. Results and Discussion: There’s significant difference between 25-hydroxyvitamin-D2 and 25-hydroxyvitamin-D3 and the BMI levels of the subjects(p:0.028<0.05-p:0.000<0.05). The average 25-hydroxyvitamin-D3 and 25-hydroxyvitamin-D2 levels of overweight participants were significantly higher than the mean levels of underweight participants’. No significant relationship was found between 25-hydroxyvitamin-D3 and 25-hydroxyvitamin-D2 levels and the time spent outdoors during summer and winter. Conclusion: To prevent vitamin D deficiency and insufficiency is to obtain some sensible sun exposure, ingest foods that contain vitamin D, and take supplement. Bangladesh Journal of Medical Science Vol.19(2) 2020 p.229-236

Prevalence of Vitamin D Deficiency among Patients Attending a General Otolaryngology Clinic in South Auckland

2009 ◽  
Vol 118 (5) ◽  
pp. 326-328 ◽  
Author(s):  
Jim Bartley ◽  
David Reid ◽  
Randall P. Morton
Keyword(s):  
Vitamin D ◽  
Statistical Analysis ◽  
Vitamin D Deficiency ◽  
Prospective Observational Study ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
Relationship Of ◽  
The Relationship

Objectives: We performed a prospective observational study to estimate the prevalence of vitamin D deficiency in patients attending a general otolaryngology clinic in South Auckland, New Zealand. Methods: From July 21, 2008, to August 7, 2008, all new patients presenting to otolaryngology clinics at which one of the authors (D.R.) was present had their vitamin D status assessed by measurement of their plasma 25-hydroxyvitamin D [25(OH)D] level. Results: Of 48 patients, 2% had 25(OH)D levels of 17.5 nmol/L or less (a level associated with osteomalacia), 58% had 25(OH)D levels of 50 nmol/L or less (a level associated with vitamin D deficiency), and 100% had 25(OH)D levels of 80 nmol/L or less. Conclusions: Most of the patients attending a general otolaryngology clinic in South Auckland are vitamin D–deficient. It is unclear whether low vitamin D levels are associated more directly with otolaryngological disorders or skin type, because the small size of this study and the broad range of conditions seen precluded a meaningful statistical analysis. Further research into the relationship of vitamin D to specific otolaryngological presentations is required.

scholarly journals Association of serum 25-hydroxyvitamin D with prevalence, incidence, and clearance of vaginal HPV infection in young women

2020 ◽  
Author(s):  
Mariam El-Zein ◽  
Farzin Khosrow-Khavar ◽  
Ann N Burchell ◽  
Pierre-Paul Tellier ◽  
Shaun Eintracht ◽  
...  
Keyword(s):  
Vitamin D ◽  
Proportional Hazards ◽  
Hpv Infection ◽  
Cox Proportional Hazards ◽  
Baseline Serum ◽  
Hpv Dna ◽  
Hydroxyvitamin D ◽  
Hpv Prevalence ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D

Abstract Background We assessed the association between serum 25-hydroxyvitamin D levels and genital human papillomavirus (HPV) prevalence, incidence, and clearance among female participants of the HITCH cohort study. Methods We genotyped HPV DNA in vaginal samples and quantified baseline serum 25-hydroxyvitamin D levels using Roche’s Linear Array and Total vitamin D assay, respectively. We used logistic and Cox proportional hazards models to respectively estimate adjusted odds ratios (OR) and hazards ratios (HR) with 95% confidence intervals (CI). Results There was no association between vitamin D levels (every 10ng/mL increase) at baseline and HPV prevalence (OR=0.88, CI:0.73-1.03) or incidence (HR=0.88, CI:0.73-1.06), but we observed a modest negative association with HPV clearance (HR=0.76, CI:0.60-0.96). Vitamin D levels &lt;30ng/mL, compared to ≥30ng/mL, were not associated with HPV prevalence (OR=0.98, CI:0.57-1.69) or incidence (HR=0.87, CI:0.50-1.43), but were associated with a marginally significant increased clearance (OR=2.14, CI:0.99-4.64). We observed consistent results with restricted cubic spline modelling of vitamin D levels and clinically defined categories. HPV type-specific analyses accounting for multiple HPV infections per participant showed no association between vitamin D levels and all study outcomes. Conclusion This study provided no evidence of an association between low vitamin D levels and increased HPV prevalence, acquisition, or clearance.

scholarly journals Prevalence of vitamin D level in the serum of patients living in Erbil city, Iraq, referred to private clinical laboratory and effect of age and sex on it

2018 ◽  
Vol 91 (1) ◽  
Author(s):  
Rabar M. Abdulrahman ◽  
Balen Muhsin Abdul Rahman
Keyword(s):  
Vitamin D ◽  
Clinical Laboratory ◽  
Mediterranean Country ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
Study Population ◽  
25 Hydroxyvitamin D ◽  
Country People ◽  
Effect Of Age ◽  
Age And Sex

This retrospective study aimed to determine the levels of 25- hydroxyvitamin D [25-(OH) D] in the individuals that have been referred to two laboratories (Bio Lab and King Lab) and to around 50 private side laboratories that use both Bio Lab and King Lab as a referral lab for their tests, in Erbil city, Iraq. Then show the range of deficiency and its relation with sunlight exposure, sex and age. Out of the total number of cases (N=10823), large percentage (nearly 78%) referred to both clinical laboratory based in Erbil city were found to have a deficiency in vitamin D levels, which means they had 25-(OH) D levels lower than 20 μg/L. This study found the percentage of vitamin D level in the serum of groups insufficient, deficient, adequate, optimal; intoxication were 52.8, 24.1, 11, 12 and 0.2% respectively. When the records have been compared according to gender, the results suggested that there was no difference between male and female within the study population (P>0.05), while there was difference in the grouped ages (P<0.05). Our results indicate that although Erbil is located in a Mediterranean country, people living there should periodically check their 25-(OH) D levels, in order to get appropriate supplements of vitamin D, which eventually prevents secondary chronic disease due to vitamin D deficiency.

scholarly journals Vitamin D Status and Seasonal Variation among Danish Children and Adults: A Descriptive Study

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1801 ◽  
Author(s):  
Louise Hansen ◽  
Anne Tjønneland ◽  
Brian Køster ◽  
Christine Brot ◽  
Rikke Andersen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Supplement Use ◽  
Wide Range ◽  
Adults And Children ◽  
25 Hydroxyvitamin D ◽  
Vitamin D Supplement ◽  
Very High

The aim of the present study was to describe vitamin D status and seasonal variation in the general Danish population. In this study, 3092 persons aged 2 to 69 years (2565 adults, 527 children) had blood drawn twice (spring and autumn) between 2012 and 2014. A sub-sample of participants had blood samples taken monthly over a year. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured by liquid chromatography mass spectrometry, and information on supplement use was assessed from questionnaires. Seasonal variations in 25(OH)D concentrations were evaluated graphically and descriptively, and status according to age, sex, and supplement use was described. It was found that 86% of both adults and children were vitamin D-sufficient in either spring and or/autumn; however, many had a spring concentration below 50 nmol/L. A wide range of 25(OH)D concentrations were found in spring and autumn, with very low and very high values in both seasons. Among adults, women in general had higher median 25(OH)D concentrations than men. Furthermore, vitamin D supplement use was substantial and affected the median concentrations markedly, more so during spring than autumn. Seasonal variation was thus found to be substantial, and bi-seasonal measurements are vital in order to capture the sizable fluctuations in vitamin D status in this Nordic population.

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