Vitamin D (25-OH) concentrations in hospitalized patients, outpatients and dialysis patients depending on seasonal variation

2015 ◽  
Vol 51 (3) ◽  
pp. 209-212
Author(s):  
Magdalena Maria Ostrowska ◽  
Ewa Szulc-Mysińska ◽  
Dagna Bobilewicz ◽  
Marta Faryna
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Seasonal Changes ◽  
Hospitalized Patients ◽  
Optimum Concentration ◽  
Dialysis Patients ◽  
Total Vitamin ◽  
Different Seasons ◽  
Mean Concentration ◽  
Global Health Problem

Vitamin D deficiency, which is a global health problem, may result in numerous diseases, such as rickets in children and osteoporosis and osteomalacia in adults. The occurrence of the above-mentioned disorders is promoted by the wintertime and higher latitudes. The aim of the study was to compare the concentrations of vitamin D (25-OH) in hospitalized patients and outpatients in different seasons of the year (summer and winter), as well as in dialysis patients in December and May. The Roche test for the quantitativedetermination of total vitamin D (25-OH) was used in the study. The range from 30 to 80 ng/ml was accepted as the optimum concentration. In hospitalized patients and outpatients, both in summer and winter mean concentration of vitamin D (25-OH) reached the values below 30 ng/ml in over 80% of the patients. Only in the hospitalized patient group mean concentration of vitamin D (25-OH) in the summer was significantly higher than in the winter (p=0.0016). In the dialysis patients mean concentration of vitamin (25-OH) in May was significantly higher than in December (p=0.0085) and the percent of the results below 30 ng/ml amounted to 96.39% in December and 77.27% in May. In conclusion, the 25(OH)D concentrations in the whole population under study are lower than those recommended and undergo periodical seasonal changes in hospitalized patients.

scholarly journals Hypovitaminosis D in an Italian population of healthy subjects and hospitalized patients

1999 ◽  
Vol 81 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Elisabetta Romagnoli ◽  
Patrizia Caravella ◽  
Liliana Scarnecchia ◽  
Paolo Martinez ◽  
Salvatore Minisola
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Postmenopausal Women ◽  
Healthy Subjects ◽  
Hypovitaminosis D ◽  
Hospitalized Patients ◽  
Italian Population ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Group D

The present study aimed to investigate the prevalence and seasonal variation of hypovitaminosis D (defined as serum 25-hydroxyvitamin D level below 30 nmol/l) among healthy subjects and hospitalized patients living in central Italy. We studied 297 subjects, 131 in February 1997 and 166 in July 1997, subdivided into four groups: (a) young healthy blood donors; (b) healthy postmenopausal women; (c) inpatients with various medical diseases and (d) inpatients engaged in long-term rehabilitation programmes because of various neurological disorders. In all subjects and patients serum levels of 25-hydroxyvitamin D were measured by radioimmunoassay. We found a significant seasonal variation (P< 0·0001) of serum 25-hydroxyvitamin D levels, mean values being higher in summer in all groups, except in patients with a longer hospitalization time (group (d)). In each group, a significantly higher prevalence of hypovitaminosis D was found in winter compared with summer time (P< 0·001), being unexpectedly high in postmenopausal women (winter 32 % and summer 4·5 %); furthermore, in both seasons, inpatients were characterized by the highest incidences of hypovitaminosis, particularly those in group (d) (winter 82·3 % and summer 57·8 %). The results of the present study emphasize the importance of 25-hydroxyvitamin D measurement, and the need to increase vitamin D intake in Italy; foodstuff fortification and supplement use must be considered in order to prevent negative effects of vitamin D deficiency on skeletal integrity.

Seasonal Changes in Vitamin D Status and Bone Turnover in Healthy Irish Postmenopausal Women

2007 ◽  
Vol 77 (5) ◽  
pp. 320-325 ◽  
Author(s):  
Hill ◽  
McCarthy ◽  
Jakobsen ◽  
Lamberg-Allardt ◽  
Kiely ◽  
...  
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Bone Turnover ◽  
Postmenopausal Women ◽  
Seasonal Changes ◽  
Late Summer ◽  
Late Winter ◽  
Vitamin D Status ◽  
Old Irish ◽  
The Impact

Objectives: To examine the effect of season on biochemical markers of bone turnover in 51-to 75-year-old Irish women and to investigate whether such changes are related to vitamin D status. Design: Longitudinal observational study. Setting: Cork, Ireland (52ºN). Subjects: 76 apparently healthy, free-living postmenopausal women (aged 51–75 years), not taking any medication and free from any condition likely to affect vitamin D status or calcium/bone metabolism. Results: Serum 25-hydroxyvitamin D [S-25(OH)D] showed a clear seasonal variation with significantly higher (p < 0.001) values during late summer than late winter. Both urinary pyridinoline (Ur-Pyr) (p < 0.01) and deoxypyridinoline (Ur-Dpyr) (p < 0.001), but not serum parathyroid hormone or osteocalcin, showed a marked seasonal variation with lowest values during late-summer. Stratifying women into those with S-25(OH)D levels ≥ or < 50 nmol/L (vitamin D adequate and inadequate, respectively) during late-winter, showed that Ur-Pyr and Ur-Dpyr in both groups were significantly (p < 0.05) lower during late summer, and the magnitude of the reduction from winter to summer was similar in both groups. Conclusion: Seasonal changes in bone resorption markers appeared to be linked to seasonal changes in vitamin D status. Further research is needed to investigate the impact of these changes on risk of bone loss and fracture.

SEASONAL VARIATION IN VITAMIN D STATUS AMONG FRAIL OLDER HOSPITALIZED PATIENTS

2018 ◽  
pp. 1-5
Author(s):  
M. POURHASSAN ◽  
R. WIRTH
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Vitamin D Deficiency ◽  
Seasonal Variations ◽  
Vitamin D Supplementation ◽  
Hospitalized Patients ◽  
Vitamin D Status ◽  
Older Individuals ◽  
Vitamin D Levels ◽  
Sufficient Vitamin

Background and objectives: Seasonal variation in 25-hydroxyvitamin D [25(OH)D] levels is the result of sunlight dependent skin synthesis of vitamin D. However, its presence is not studied in frail older hospitalized patients. We sought to investigate whether seasonal variation in 25(OH)D levels is evident among these patients. Design and setting: This study investigated older participants who were consecutively admitted between February 2015 and December 2016 to the geriatric acute care ward. Results of routine measurements of 25(OH)D at hospital admission were retrospectively analyzed and stratified according to months and seasons. Previous intake of vitamin D supplementation was derived from the patients’ medical records. Results: The study group comprised 679 participants (mean age 82.1±8.2; 457 females), of which 78% had vitamin D deficiency. Older individuals not taking vitamin D supplements had a lower mean serum 25(OH)D than those receiving supplements. Of those patients with no vitamin D supplementation, 87.0% were vitamin D deficient and only 5% showing sufficient vitamin 25(OH)D. Further, there were neither monthly nor seasonal variations in vitamin 25(OH)D levels among these patients and their vitamin D levels stayed far below the recommended threshold of 20 ng/ml across the seasons. Conclusion: Vitamin D deficiency was very prevalent in the subgroup of older hospitalized patients without vitamin D supplementation, irrespective of season. Since no seasonal variations in mean 25(OH)D levels was observed, sunlight dependent skin synthesis is unlikely to contribute to vitamin D status in these patients. Supplementation seems to be necessary to maintain desirable vitamin D levels among this population throughout the year.

Seasonal changes of energy reserves in Bulimulus tenuissimus (d'Orbigny, 1835) (Mollusca, Bulimulidae)

2012 ◽  
Vol 62 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Flávia Oliveira Junqueira ◽  
Lidiane Silva ◽  
Jairo Pinheiro ◽  
Elisabeth Cristina de Almeida Bessa ◽  
Liliane Meireles
Keyword(s):  
Seasonal Variation ◽  
Energy Metabolism ◽  
Digestive Gland ◽  
Seasonal Changes ◽  
Reproductive Period ◽  
Regulatory Mechanisms ◽  
Energy Reserves ◽  
Energy Substrates ◽  
Different Seasons ◽  
Energetic Reserves

AbstractThe objective of this study was to evaluate the variation of energy substrates in different seasons in Bulimulus tenuissimus. For this evaluation, substrates were collected from the digestive and albumen glands and foot tissues, which were processed to obtain the concentrations of glucose and galactose. There was seasonal variation in energy reserves in both the digestive gland and the foot of Bulimulus tenuissimus, with a tendency to accumulation from spring to winter. There was greater use of energetic reserves in the spring and summer, being the glycogen stored in the digestive gland the first source consumed. In addition, mobilization of reserves of glycogen in the muscle in summer was observed. The reduction of glycogen coincides with the reproductive cycle of the species, and the expenses generated for the processes of mating and gametogenesis was the cause of this reduction. The concentration of galactogen also varied according to the reproductive period. It was suggested that variations in temperature and photoperiod that occur during the year would act as regulatory mechanisms of energy metabolism of B. tenuissimus.

Lipid profiles and vitamin D receptor polymorphisms in overweight/obese dialysis patients

2017 ◽  
Author(s):  
Gokhan Bagci ◽  
Can Huzmeli ◽  
Binnur Bagci ◽  
Ferhan Candan ◽  
Lale Akkaya ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Lipid Profiles ◽  
Dialysis Patients

scholarly journals Seasonal Variation of Kaurenoic Acid, a Hypoglycemic Diterpene Present in Wedelia paludosa (Acmela brasiliensis) (Asteraceae)

2004 ◽  
Vol 59 (3-4) ◽  
pp. 229-232 ◽  
Author(s):  
Louisiane Faccio V. Bresciania ◽  
Rosendo Augusto Yunes ◽  
Cristiani Bürger ◽  
Luis Eduardo De Oliveira ◽  
Kauê Leal Bóf ◽  
...  
Keyword(s):  
Seasonal Variation ◽  
Kaurenoic Acid ◽  
Different Seasons ◽  
Hypoglycemic Diterpene

We evaluated the variation of the concentration of kaurenoic acid (1), which is a bioactive diterpene, in leaves, flowers, stems and roots from Wedelia paludosa (Acmela brasiliensis) for different seasons using the HRGC/FID method. The results indicated that the concentration of 1 is higher in the roots and stems during the autumn. The pharmacological results suggested that kaurenoic acid is responsible, at least in part, for the hypoglycemic potential detected in this plant.

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