Porphyrin-Catalyzed Oxidation of N-Substituted Tetrahydroisoquinolines to Dihydroisoquinolones
Keyword(s):
A visible-light-induced direct α-oxygenation of N-substituted tetrahydroisoquinoline derivatives has been successfully developed. Metalloporphyrin (ZnTPP) has been identified as an effective and inexpensive photocatalyst for this transformation with a wide range of substrates. This protocol provides a convenient route to afford the desired products in moderate to good yields at room temperature under air atmosphere.
1976 ◽
Vol 34
◽
pp. 592-593
Keyword(s):
2005 ◽
Vol 50
(2)
◽
pp. 195-210
◽
Keyword(s):