Effect of Strontium Ranelate on Lumbar Spine Bone Mineral Density in Women with Established Osteoporosis Previously Treated with Teriparatide

2009 ◽  
Vol 41 (07) ◽  
pp. 559-562 ◽  
Author(s):  
A. Anastasilakis ◽  
S. Polyzos ◽  
A. Avramidis ◽  
A. Papatheodorou ◽  
E. Terpos
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Strontium Ranelate ◽  
Spine Bone Mineral Density ◽  
Mineral Density ◽  
Established Osteoporosis ◽  
Previously Treated

scholarly journals Trajectories of Bone Remodeling Markers and Bone Mineral Density during Treatment with Strontium Ranelate in Postmenopausal Women Previously Treated with Bisphosphonates

2014 ◽  
Vol 7 ◽  
pp. CMED.S15086 ◽  
Author(s):  
Helisane Lima ◽  
Juliana Maia ◽  
Francisco Bandeira
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Strontium Ranelate ◽  
Mineral Density ◽  
Bone Remodeling Markers ◽  
Before And After ◽  
Previously Treated

Objective To evaluate the responses of C-terminal telopeptide (CTX) and serum osteocalcin after the first 4 months of treatment with strontium ranelate (SR) and demonstrate their association with long-term bone density changes. Subjects and Methods A sample of 13 postmenopausal women with osteoporosis was analyzed (mean age 65 ± 7.7 years), who were treated with SR for an average of 2.56 ± 0.86 years. All patients had undergone previous treatment with bisphosphonates for an average period of 4.88 ± 2.27 years. Serum CTX and osteocalcin levels were determined before and after four months of treatment with SR. Bone mineral density in the lumbar spine and femoral neck were obtained before and after treatment with SR. Results We observed an average increase of 53.7% in the CTX levels, and 30.7% in the osteocalcin levels. The increase in bone markers was associated with a mean 4.8% increase in lumbar spine bone mineral density (BMD) from 0.820 to 0.860 g/cm2 ( T-score from –2.67 to –1.92; P= 0.001), after 2.5 years of treatment with SR. Conclusion These data suggest an anabolic effect of SR on postmenopausal women who were previously treated with long-term bisphosphonates.

Poster 43: Effect of Intravenous Zoledronic Acid on Lumbar Spine Bone Mineral Density Compared to Oral Risedronate in Subgroups of Patients Receiving Glucocorticoid Therapy

PM&R ◽  
2009 ◽  
Vol 1 ◽  
pp. S121-S122
Author(s):  
Kenneth Saag ◽  
Jean-Pierre Devogelaer ◽  
Peter Mesenbrink ◽  
Philemon Papanastasiou ◽  
Jean-Yves L. Reginster ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Zoledronic Acid ◽  
Bone Mineral ◽  
Spine Bone Mineral Density ◽  
Glucocorticoid Therapy ◽  
Mineral Density

Carotid plaque and lumbar bone mineral density status in post-menopausal women: An age-matched, analytical cross-sectional study

2019 ◽  
Vol 26 (1) ◽  
pp. 9-18
Author(s):  
Patraporn Sitthisombat ◽  
Sukree Soontrapa ◽  
Srinaree Kaewrudee ◽  
Jen Sothornwit ◽  
Nuntasiri Eamudomkarn ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cardiovascular Disease ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Odds Ratio ◽  
Carotid Plaque ◽  
Spine Bone Mineral Density ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

Objective To explore the association between carotid plaque and lumbar spine osteoporosis in post-menopausal women. Study design Age-matched, cross-sectional study. Main outcome measures Carotid plaque and carotid intima media thickness were measured with B-mode ultrasound. Lumbar spine bone mineral density was measured with dual-energy X-ray absorptiometry. Prevalence odds ratios and the respective 95% confidence intervals (95%CI) were calculated to determine the association. Results Seventy-two post-menopausal women with lumbar spine osteoporosis and 72 post-menopausal women with normal lumbar spine bone mineral density were enrolled. The adjusted prevalence odds ratio of carotid plaque presence in post-menopausal women with lumbar spine osteoporosis was 1.73 (95%CI; 0.60 to 4.94) when compared to post-menopausal women with normal lumbar spine bone mineral density. The presence of vulnerable plaque was greater in post-menopausal women with lumbar spine osteoporosis; however, the difference was not statistically significant after adjusting for other risk factors of cardiovascular disease (odds ratio 1.31; 95%CI; 0.39 to 4.43). There was no significant difference in carotid intima media thickness between the two groups. Multiple logistic regression analysis with backward elimination in assessment of potential risk factors for the presence of carotid plaque showed that the year since menopause, family history of cardiovascular disease and systolic blood pressure were nominally significant associated factors with a respective adjusted odds ratio of 1.06 (95%CI; 1.01 to 1.12), 6.23 (95%CI; 1.65 to 23.46) and 1.03 (95%CI; 1.01 to 1.06). Conclusions The current study indicates that lumbar spine osteoporosis is not associated with the presence of carotid plaque, whereas year since menopause, family history of cardiovascular disease and systolic blood pressure are associated factors.

scholarly journals 855 LEAN BODY MASS AND LUMBAR SPINE BONE MINERAL DENSITY IN PREMENOPAUSAL WOMEN

1993 ◽  
Vol 25 (Supplement) ◽  
pp. S153 ◽  
Author(s):  
J. Shaw ◽  
C. Snow-Harter ◽  
T. Robinson ◽  
M. Wegner ◽  
A. Shelley
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Lean Body Mass ◽  
Body Mass ◽  
Bone Mineral ◽  
Premenopausal Women ◽  
Spine Bone Mineral Density ◽  
Mineral Density

scholarly journals Hand bone mineral density is associated with both total hip and lumbar spine bone mineral density in post-menopausal women with RA

Rheumatology ◽  
2009 ◽  
Vol 49 (3) ◽  
pp. 513-519 ◽  
Author(s):  
S. P. Desai ◽  
E. M. Gravallese ◽  
N. A. Shadick ◽  
R. Glass ◽  
J. Cui ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Spine Bone Mineral Density ◽  
Mineral Density ◽  
Total Hip ◽  
Menopausal Women ◽  
Post Menopausal
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