In Vitro Expansion of Human Regulatory T Cells for Functional Study of Allograft Rejection in a Humanized Mouse Model

2016 ◽  
Vol 64 (S 01) ◽  
Author(s):  
L. Pauksch ◽  
W. Sommer ◽  
K. Jansson ◽  
A.-K Knoefel ◽  
T. Nakagiri ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Mouse Model ◽  
Allograft Rejection ◽  
Functional Study ◽  
Humanized Mouse ◽  
Humanized Mouse Model ◽  
In Vitro Expansion

scholarly journals Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Sija Landman ◽  
Vivian L. de Oliveira ◽  
Piet E. J. van Erp ◽  
Esther Fasse ◽  
Stijn C. G. Bauland ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Mouse Model ◽  
Low Dose ◽  
Skin Inflammation ◽  
Intradermal Injection ◽  
Humanized Mouse ◽  
Humanized Mouse Model

scholarly journals Regulatory T Cells Prevent Liver Fibrosis During HIV Type 1 Infection in a Humanized Mouse Model

2013 ◽  
Vol 209 (7) ◽  
pp. 1039-1044 ◽  
Author(s):  
Jun-ichi Nunoya ◽  
Michael L. Washburn ◽  
Grigoriy I. Kovalev ◽  
Lishan Su
Keyword(s):  
T Cells ◽  
Liver Fibrosis ◽  
Regulatory T Cells ◽  
Mouse Model ◽  
Humanized Mouse ◽  
Humanized Mouse Model ◽  
Hiv Type 1

scholarly journals Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model

2013 ◽  
Vol 96 (8) ◽  
pp. 707-716 ◽  
Author(s):  
Douglas C. Wu ◽  
Joanna Hester ◽  
Satish N. Nadig ◽  
Wei Zhang ◽  
Piotr Trzonkowski ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Mouse Model ◽  
Ex Vivo ◽  
Human Islet ◽  
Humanized Mouse ◽  
Humanized Mouse Model ◽  
Islet Allograft

Soluble GARP has potent antiinflammatory and immunomodulatory impact on human CD4+ T cells

Blood ◽  
2013 ◽  
Vol 122 (7) ◽  
pp. 1182-1191 ◽  
Author(s):  
Susanne A. Hahn ◽  
Heiko F. Stahl ◽  
Christian Becker ◽  
Anita Correll ◽  
Franz-Joseph Schneider ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Regulatory T Cells ◽  
Mouse Model ◽  
Cd4 T Cells ◽  
Humanized Mouse ◽  
Humanized Mouse Model ◽  
Key Points ◽  
Destructive Inflammation

Key Points GARP efficiently represses proliferation of naïve and resting CD4+ T cells and is involved in the induction of adaptive regulatory T cells. In vivo, GARP prevents T cell–mediated destructive inflammation in a preclinical humanized mouse model of GVHD.

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