Rater Reliability of the Hardy Classification for Pituitary Adenomas in the Magnetic Resonance Imaging Era

Objectives The Hardy classification is used to classify pituitary tumors for clinical and research purposes. The scale was developed using lateral skull radiographs and encephalograms, and its reliability has not been evaluated in the magnetic resonance imaging (MRI) era. Design Fifty preoperative MRI scans of biopsy-proven pituitary adenomas using the sellar invasion and suprasellar extension components of the Hardy scale were reviewed. Setting This study was a cohort study set at a single institution. Participants There were six independent raters. Main Outcome Measures The main outcome measures of this study were interrater reliability, intrarater reliability, and percent agreement. Results Overall interrater reliability of both Hardy subscales on MRI was strong. However, reliability of the intermediate scores was weak, and percent agreement among raters was poor (12–16%) using the full scales. Dichotomizing the scale into clinically useful groups maintained strong interrater reliability for the sellar invasion scale and increased the percent agreement for both scales. Conclusion This study raises important questions about the reliability of the original Hardy classification. Editing the measure to a clinically relevant dichotomous scale simplifies the rating process and may be useful for preoperative tumor characterization in the MRI era. Future research studies should use the dichotomized Hardy scale (sellar invasion Grades 0–III versus Grade IV, suprasellar extension Types 0–C versus Type D).

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Magnetic Resonance Imaging in Psoriatic Arthritis — Update on Current Status and Future Perspectives: A Report from the GRAPPA 2010 Annual Meeting

The Journal of Rheumatology ◽

10.3899/jrheum.111235 ◽

2012 ◽

Vol 39 (2) ◽

pp. 408-412 ◽

Cited By ~ 8

Author(s):

MIKKEL ØSTERGAARD ◽

RENÉ PANDURO POGGENBORG

Keyword(s):

Magnetic Resonance Imaging ◽

Psoriatic Arthritis ◽

Magnetic Resonance ◽

Annual Meeting ◽

Current Status ◽

Future Research ◽

Future Perspectives ◽

Resonance Imaging ◽

Primary Driver ◽

Magnetic Resonance Imaging Mri

The potential of magnetic resonance imaging (MRI) for use in clinical practice and research has gained increasing interest over the last decade. International collaborative initiatives from GRAPPA (Group for Research and Assessment of Psoriasis and Psoriatic Arthritis) and/or OMERACT (Outcome Measures in Rheumatology) may contribute to facilitating research, identifying appropriate areas for use, and reaching consensus on the optimal examination technique. Accordingly, GRAPPA, a primary driver of international research in psoriasis and psoriatic arthritis (PsA), has focused on the current use and future development of MRI and other modern imaging modalities in PsA. This review, presented at the GRAPPA 2010 annual meeting, describes the current status of MRI in PsA, with a focus on its use in diagnosis, monitoring, and prediction of the disease course and treatment response. Important areas for future research are also outlined.

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The Utility of Magnetic Resonance Imaging in Assessing Patients With Pituitary Tumors Compressing the Anterior Visual Pathway

Journal of Neuro-Ophthalmology ◽

10.1097/wno.0000000000000408 ◽

2017 ◽

Vol 37 (3) ◽

pp. 230-238 ◽

Cited By ~ 6

Author(s):

Won Hyung A. Ryu ◽

Yves Starreveld ◽

Jodie M. Burton ◽

Junjie Liu ◽

Fiona Costello

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Pituitary Tumors ◽

Visual Pathway ◽

Resonance Imaging

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Consumer Neuroscience and its Application in Marketing

International Journal of Recent Technology and Engineering - 2 ◽

10.35940/ijrte.c4248.118419 ◽

2019 ◽

Vol 8 (4) ◽

pp. 1607-1611

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Functional Magnetic Resonance Imaging ◽

Skin Conductance ◽

Market Research ◽

Future Research ◽

Functional Magnetic Resonance ◽

Resonance Imaging ◽

Consumer Neuroscience ◽

Basic Ideas

There is a very important difference between “Consumer neuroscience” and “Neuromarketing”. While the first field deals in research on subjects like neuroscience, psychology and marketing; the latter is linked to the functionality of neurophysiological tools, namely eye tracking, skin conductance, electroencephalography (EEG), and functional magnetic resonance imaging (fMRI). Neuromarketing is interested in carrying out market research which is specific to a particular company. This article covers topics like recent methods in neuroscience used by consumer researchers, basic ideas in consumer neuroscience derived on the basis of initial findings. The article also suggests ideas for future research in the field of consumer neuroscience.

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Magnetic Resonance Imaging of Parasellar Developed Pituitary Adenomas: New Consequences for Pituitary Surgery

Surgery of the Sellar Region and Paranasal Sinuses ◽

10.1007/978-3-642-76450-9_35 ◽

1991 ◽

pp. 199-204 ◽

Cited By ~ 2

Author(s):

R. Nistor ◽

R. Fahlbusch ◽

M. Buchfelder ◽

W. Huk

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Pituitary Adenomas ◽

Pituitary Surgery ◽

Resonance Imaging

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Visualisation of fetal meconium on post-mortem magnetic resonance imaging scans: a retrospective observational study

Acta Radiologica Open ◽

10.1177/2058460120970541 ◽

2020 ◽

Vol 9 (11) ◽

pp. 205846012097054

Author(s):

Georgia Hyde ◽

Andrew Fry ◽

Ashok Raghavan ◽

Elspeth Whitby

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Signal Intensity ◽

Interrater Reliability ◽

Hepatic Flexure ◽

Radiology Department ◽

High Signal ◽

Post Mortem ◽

Resonance Imaging ◽

Tertiary Referral Centre

Background Less invasive techniques for fetal post-mortems are increasingly used to correlate with parental wishes. With the use of post-mortem magnetic resonance imaging (MRI), normal appearance of the organs must be established. Purpose To investigate the after death appearance of the fetal meconium throughout gestation using the hyperintense appearance of meconium on T1 weighted MRI. Material and Methods This was a retrospective study that took place in a tertiary referral centre radiology department. Sixty-two fetal body post-mortem MRI scans (January 2014 to May 2018) between 12 and 41 weeks gestation were reviewed. Signal intensity of meconium at the rectum, sigmoid colon, splenic flexure and hepatic flexure was evaluated and correlated with gestational age. Interrater reliability was calculated. Results Meconium did not consistently have high signal intensity on T1 scans and was not always obvious. Rectal meconium had the highest intensity, and the more proximal the bowel the lower the intensity. The meconium had higher intensity at earlier gestations. Interrater reliability for rectal meconium gradings was excellent. Conclusion This study provides the first published primary research on the appearance of fetal meconium on post-mortem MRI. Overall, results were variable and suggest an alteration of bowel contents after death, but further investigation is needed to effectively inform practice.

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High-Field Intraoperative Magnetic Resonance Imaging Increases Extent of Resection and Progression-Free Survival for Nonfunctioning Pituitary Adenomas

World Neurosurgery ◽

10.1016/j.wneu.2019.04.001 ◽

2019 ◽

Vol 127 ◽

pp. e925-e931 ◽

Cited By ~ 1

Author(s):

Zhibin Zhang ◽

Kai Yang ◽

Yirong Xia ◽

Xianghui Meng ◽

Xinguang Yu

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Pituitary Adenomas ◽

High Field ◽

Progression Free Survival ◽

Extent Of Resection ◽

Resonance Imaging ◽

Free Survival ◽

Intraoperative Magnetic Resonance Imaging ◽

Nonfunctioning Pituitary Adenomas

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Autologous Chondrocyte Implantation to Isolated Patella Cartilage Defects

Cartilage ◽

10.1177/1947603516654944 ◽

2016 ◽

Vol 8 (2) ◽

pp. 146-154 ◽

Cited By ~ 19

Author(s):

Arvind von Keudell ◽

Roger Han ◽

Tim Bryant ◽

Tom Minas

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Outcome Measures ◽

Autologous Chondrocyte Implantation ◽

Tibial Tubercle ◽

Resonance Imaging ◽

Patient Reported ◽

Chondrocyte Implantation ◽

Autologous Chondrocyte

Background Autologous chondrocyte implantation (ACI) is a durable treatment for patients with chondral defects. This study presents the comprehensive evaluation of patients with patella defects treated with ACI at medium- to long-term follow-up. Methods Thirty consecutive patients with isolated chondral lesions of the patella were enrolled prospectively. Primary outcome measures were validated patient reported outcome measures and objective magnetic resonance imaging. Results Nineteen of 30 patients underwent tibial tubercle osteotomy (TTO) to correct lateral maltracking in combination with soft tissue balancing. The defect sizes were large, averaging 4.7 ± 2.1 cm2 (range 2.2-30.0 cm2). Pidoriano/Fulkerson classification revealed that 3 defects were type II (lateral), 9 were type III (medial), and 18 were type IV (central/panpatella). Age at the time of surgery was 32 ± 10 years. At follow-up of 2 to 14 years, knee function was rated good to excellent in 25 (83%) patients, fair in 4 (13%) patients, and poor in 1 (3%) patient. Three patients failed treatment after a mean of 75 months (6.25 years). All 3 failures were Workers Compensation (WC) cases. They were older than the non-WC patients, 42 ± 6 years compared with the non-WC 28 ± 9 years ( P = 0.0019). Significant increases in all clinical and health utility outcome scores were seen. Magnetic resonance imaging demonstrated that the fill grade, surface and integrity of the repair tissue correlated with clinical scores. Conclusion ACI to isolated patella defects results in significant functional improvement at a minimum of 24 months, with the results remaining durable at latest follow-up of 15 years. Level of evidence Level 4.

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Clinical use of structural magnetic resonance imaging in the diagnosis of dementia in adults with Down's syndrome

Irish Journal of Psychological Medicine ◽

10.1017/s0790966700006984 ◽

2002 ◽

Vol 19 (2) ◽

pp. 60-63 ◽

Cited By ~ 9

Author(s):

Andre Strydom ◽

Angela Hassiotis ◽

Zuzana Walker

Keyword(s):

Magnetic Resonance Imaging ◽

Clinical Practice ◽

Magnetic Resonance ◽

Current Knowledge ◽

Down's Syndrome ◽

Down’S Syndrome ◽

Brain Structures ◽

Future Research ◽

Resonance Imaging ◽

Mri Studies

AbstractObjectives: Magnetic Resonance Imaging (MRI) has been used to assist the diagnosis of Alzheimer's Disease (AD) in adults with Down's syndrome (DS). However, the interpretation of the scans is difficult and clinical usefulness is uncertain. We aimed to summarise the current knowledge of MRI studies in adults with Down's syndrome with and without dementia and to discuss its implications for clinical practice.Method: We identified MRI studies in DS by a computerised literature search with Medline, Embase, and Psychlit from 1986 to 2001. We examined the references of identified articles and hand searched relevant journals. Structural MRI studies were selected as this type of imaging is most frequently used in clinical practice.Results: We included eight volumetric studies in adults with DS. Four of these included adults with DS and dementia. Overall, the size of brain structures such as cerebellum, hippocampus and cortex of adults with DS without dementia was significantly smaller than in normal controls. The basal ganglia were similar in size, and ventricles were enlarged. Furthermore, the size of brain structures in adults with DS and dementia was significantly different than in DS without dementia. In particular, ventricular and hippocampal volumes were affected.Conclusions: The change in brain structure associated with dementia can be detected on MRI of adults with DS. However, these may be difficult to interpret given the extent to which brain appearance in DS differs from that in the general population. Implications for clinical practice and future research directions are discussed.

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