scholarly journals The Role of Free/Libre and Open Source Software in Learning Health Systems

2017 ◽  
Vol 26 (01) ◽  
pp. 53-58
Author(s):  
C. Paton ◽  
T. Karopka
Keyword(s):  
Open Source ◽  
Health Systems ◽  
Open Source Software ◽  
Grey Literature ◽  
Critical Role ◽  
Patient Data ◽  
It Infrastructure ◽  
Management Tools ◽  
Wide Range

Summary Objective: To give an overview of the role of Free/Libre and Open Source Software (FLOSS) in the context of secondary use of patient data to enable Learning Health Systems (LHSs). Methods: We conducted an environmental scan of the academic and grey literature utilising the MedFLOSS database of open source systems in healthcare to inform a discussion of the role of open source in developing LHSs that reuse patient data for research and quality improvement. Results: A wide range of FLOSS is identified that contributes to the information technology (IT) infrastructure of LHSs including operating systems, databases, frameworks, interoperability software, and mobile and web apps. The recent literature around the development and use of key clinical data management tools is also reviewed. Conclusions: FLOSS already plays a critical role in modern health IT infrastructure for the collection, storage, and analysis of patient data. The nature of FLOSS systems to be collaborative, modular, and modifiable may make open source approaches appropriate for building the digital infrastructure for a LHS.

scholarly journals The Role of Free/Libre and Open Source Software in Learning Health Systems

2017 ◽  
Vol 26 (01) ◽  
pp. 53-58 ◽  
Author(s):  
C. Paton ◽  
T. Karopka
Keyword(s):  
Open Source ◽  
Health Systems ◽  
Open Source Software ◽  
Grey Literature ◽  
Critical Role ◽  
Patient Data ◽  
It Infrastructure ◽  
Management Tools ◽  
Wide Range

Summary Objective: To give an overview of the role of Free/Libre and Open Source Software (FLOSS) in the context of secondary use of patient data to enable Learning Health Systems (LHSs). Methods: We conducted an environmental scan of the academic and grey literature utilising the MedFLOSS database of open source systems in healthcare to inform a discussion of the role of open source in developing LHSs that reuse patient data for research and quality improvement. Results: A wide range of FLOSS is identified that contributes to the information technology (IT) infrastructure of LHSs including operating systems, databases, frameworks, interoperability software, and mobile and web apps. The recent literature around the development and use of key clinical data management tools is also reviewed. Conclusions: FLOSS already plays a critical role in modern health IT infrastructure for the collection, storage, and analysis of patient data. The nature of FLOSS systems to be collaborative, modular, and modifiable may make open source approaches appropriate for building the digital infrastructure for a LHS.

scholarly journals Development of cancer metabolism as a therapeutic target: new pathways, patient studies, stratification and combination therapy

2019 ◽  
Vol 122 (1) ◽  
pp. 1-3 ◽  
Author(s):  
Adrian L. Harris
Keyword(s):  
Metabolic Pathways ◽  
Trial Design ◽  
Cancer Metabolism ◽  
Aerobic Glycolysis ◽  
Critical Role ◽  
Therapeutic Approaches ◽  
Preclinical Models ◽  
Wide Range ◽  
Patient Studies

AbstractCancer metabolism has undergone a resurgence in the last decade, 70 years after Warburg described aerobic glycolysis as a feature of cancer cells. A wide range of techniques have elucidated the complexity and heterogeneity in preclinical models and clinical studies. What emerges are the large differences between tissues, tumour types and intratumour heterogeneity. However, synergies with inhibition of metabolic pathways have been found for many drugs and therapeutic approaches, and a critical role of window studies and translational trial design is key to success.

Wildlife management and the debate on the ethics of animal use. II. A challenge for the animal protection movement.

2012 ◽  
Vol 18 (2) ◽  
pp. 81 ◽  
Author(s):  
Daniel Lunney
Keyword(s):  
Wildlife Management ◽  
Critical Role ◽  
Animal Liberation ◽  
Ethical Imperative ◽  
Animal Protection ◽  
Wide Range ◽  
Animal Use

How people coexist and interact with animals has become an intensely debated issue in recent times, particularly with the rise of the animal protection movement following the publication of Peter Singer’s book Animal Liberation in 1975. This paper discusses some shortcomings of the philosophical positions taken in this complex debate. Singer has helped put animals on a new footing as a group that cannot morally be ignored, but his focus is mainly on individual, familiar animals that are used or abused by humans. The argument of this paper is that the ethics of managing wildlife hinges on a broader view of animals, and their contexts, than is apparent from Singer’s text. Wildlife managers aim to conserve populations of a wide range of species, and their habitats, but some mechanisms for achieving these aims, such as research and the control of invasive animals, are frequently opposed by elements of the animal protection movement. We need to adapt our attitude to animals, particularly wildlife, away from the traditional legacy of a few familiar species to embrace an ethic that is more ecological and relevant to Australian contexts. The case argued here has been to see the critical role of context — geographical, ecological, historical, relational — as a basis for a degree of reconciliation between conservation-oriented wildlife managers and the rising interest in the ethics of animal use. There is much to be gained for zoologists, wildlife managers and conservation biologists by framing key elements of their case in ethical arguments. Conversely, the challenge for those in the animal protection movement is to expand their philosophical ideas to include the ethical imperative of the conservation of populations of wildlife.

scholarly journals Role of OpenEHR as an open source solution for the regional modelling of patient data in obstetrics

2015 ◽  
Vol 55 ◽  
pp. 174-187 ◽  
Author(s):  
Christina Pahl ◽  
Mojtaba Zare ◽  
Mehrbakhsh Nilashi ◽  
Marco Aurélio de Faria Borges ◽  
Daniel Weingaertner ◽  
...  
Keyword(s):  
Open Source ◽  
Patient Data ◽  
Regional Modelling

JuTrack: A Digital Biomarker Platform for Remote Monitoring in Neuropsychiatric and Psychiatric Diseases (Preprint)

2021 ◽  
Author(s):  
Mehran Sahandi Far ◽  
Michael Stolz ◽  
Jona Marcus Fischer ◽  
Simon B Eickhoff ◽  
Juergen Dukart
Keyword(s):  
Data Management ◽  
Open Source ◽  
Remote Monitoring ◽  
Daily Life ◽  
Smartphone Application ◽  
Valuable Insight ◽  
Motion Sensors ◽  
Management Tools ◽  
General Data Protection Regulation ◽  
Wide Range

BACKGROUND Health-related data being collected by smartphones offer a promising complementary approach to in-clinic assessments. OBJECTIVE Here we introduce the JuTrack platform as a secure, reliable and extendable open-source solution for remote monitoring in daily-life and digital phenotyping. METHODS JuTrack consists of an Android-based smartphone application and a web-based project management dashboard. A wide range of anonymized measurements from motion-sensors, social and physical activities and geolocation information can be collected in either active or passive modes. The dashboard also provides management tools to monitor and manage data collection across studies. To facilitate scaling, reproducibility, data management and sharing we integrated DataLad as a data management infrastructure. JuTrack was developed to comply with security, privacy and the General Data Protection Regulation (GDPR) requirements. RESULTS JuTrack is an open-source (released under open-source Apache 2.0 licenses) platform for remote assessment of digital biomarkers (DB) in neurological, psychiatric and other indications. The main components of the JuTrack platform and examples of data being collected using JuTrack are presented here. CONCLUSIONS Smartphone-based Digital Biomarker data may provide valuable insight into daily life behaviour in health and disease. JuTrack provides an easy and reliable open-source solution for collection of such data.

Open Source and Outsourcing

2009 ◽  
pp. 1934-1950
Author(s):  
Kirk St. Amant
Keyword(s):  
Open Source ◽  
Open Source Software ◽  
Knowledge Work ◽  
Transfer Of Knowledge ◽  
International Outsourcing

This chapter examines the role of open source software (OSS) in international outsourcing practices that involve the transfer of knowledge work from one nation to another. Included in this examination are discussions of the benefits and the limitations of OSS use in outsourcing. The chapter also presents organization-specific and industry-wide strategies for effective OSS use in outsourcing situations. The chapter then concludes with a discussion of areas of international outsourcing where OSS might have important future applications or effects. The purpose of such an examination is to provide readers with the knowledge and the insights needed to make effective decisions related to the use of OSS in international outsourcing situations.

Community Customers

2011 ◽  
pp. 510-521 ◽  
Author(s):  
Jeroen Hoppenbrouwers
Keyword(s):  
Life Cycle ◽  
Open Source ◽  
Community Participation ◽  
Open Source Software ◽  
Product Life Cycle ◽  
Development Process ◽  
Sales Process ◽  
Software Product ◽  
Specific Community

This chapter discusses the role of the project/product community in the open source product life cycle. It outlines how a community-driven approach affects not only the development process, but also (and more importantly) the marketing/sales process, the deployment, the operation, and in general the resulting software product. Participation in the community is essential for any organization using the product, leading to the concept of a community customer. Specific community participation guidelines are given to organizations and individuals who deploy and use open source software, further develop it, or offer lifetime services on the product.

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