New PTP1B inhibiting ellagitannins from the rhizome of Thonningia sanguinea

2017 ◽  
Author(s):  
L Pompermaier ◽  
S Schwaiger ◽  
T Lautenschläger ◽  
L Mandombe José ◽  
B Waltenberger ◽  
...  
Keyword(s):  
Thonningia Sanguinea

Bio-guided isolation of anti-salmonellae compounds of Thonningia sanguinea, an Ivorian medicinal plant

Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
M Chaabi ◽  
JD N'guessan ◽  
B Weniger ◽  
A Ramanou ◽  
P Andre ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Thonningia Sanguinea

scholarly journals Influence de Thonningia sanguinea (THOS) sur la productivité d’un élevage de poules pondeuses

2013 ◽  
Vol 6 (5) ◽  
Author(s):  
K Ouattara ◽  
I Doumbia ◽  
AF Coulibaly ◽  
SK Kouakou ◽  
JD Guessan ◽  
...  
Keyword(s):  
Thonningia Sanguinea

scholarly journals Effect of Aqueous Extract of Thonningia sanguinea on Blood Electrolytes of Broilers Chickens

2020 ◽  
Vol 10 (6) ◽  
pp. 37-41
Author(s):  
Kouakou Severin KONAN ◽  
Aboya Jean-Luc MOROH ◽  
Wawa Justine TIEKPA ◽  
Jean-David N’GUESSAN
Keyword(s):  
Weight Gain ◽  
Aqueous Extract ◽  
Broiler Chickens ◽  
Test Group ◽  
Control Group ◽  
Serum Electrolytes ◽  
Blood Electrolytes ◽  
Weight Growth ◽  
Consumption Index ◽  
Thonningia Sanguinea

The aim of the present study is to evaluate the effect of aqueous extract of Thonningia sanguinea on blood electrolytes of broiler chickens. To do this, two hundred (200) 15-day-old Hubbard broiler chickens were divided into 2 batches of 100 chickens each. The chickens in the control group (Batch C) received unsupplemented water while those in the test group (Batch E) received water supplemented with 10 g / L of aqueous extract of T. sanguinea for one week. Then, the zootechnical parameters such as weight growth, weight gain, consumption index and the level of serum electrolytes were determined. The results of the study showed that the aqueous extract of Thonningia sanguinea improved weight growth, weight gain and consumption index. At the same time, the results also showed that T. sanguinea did not significantly (p <0.05) affect the level of blood electrolytes of broilers chickens. From the results obtained in the present study, the aqueous extract of Thonningia sanguinea could be used to improve poultry productivity without damage on blood electrolytes. Keywords: Thonningia sanguinea; chicken broilers; Blood electrolytes; Zootechnical parameters

scholarly journals Purification of thonningianins A and B and four further derivatives from Thonningia sanguinea by one‐ and two‐dimensional centrifugal partition chromatography

2019 ◽  
Vol 43 (2) ◽  
pp. 524-530
Author(s):  
Luca Pompermaier ◽  
Stefan Schwaiger ◽  
Monizi Mawunu ◽  
Thea Lautenschlaeger ◽  
Hermann Stuppner ◽  
...  
Keyword(s):  
Two Dimensional ◽  
Partition Chromatography ◽  
Centrifugal Partition Chromatography ◽  
Thonningia Sanguinea

Medicinal herb, Thonningia sanguinea protects against aflatoxin B1 acute hepatotoxicity in Fischer 344 rats

1998 ◽  
Vol 17 (8) ◽  
pp. 418-423 ◽  
Author(s):  
Maxwell Afari Gyamfi ◽  
Yoko Aniya
Keyword(s):  
Liver Injury ◽  
Aflatoxin B1 ◽  
Liver Microsomes ◽  
Rat Liver Microsomes ◽  
Fischer 344 Rats ◽  
Hydroxylase Activity ◽  
Aniline Hydroxylase ◽  
Fischer 344 ◽  
Cytochrome P450 Activity ◽  
Thonningia Sanguinea

1. Thonningia sanguinea, a plant used prophylactically against bronchial asthma in Ghana was recently found to have antioxidative and hepatoprotective actions in our laboratory. 2. In this study, the effect of T. sanguinea extract on certain biochemical indices in serum and liver of Fischer 344 rats given a single intraperitoneal (i.p.) dose (1 mg/kg) of aflatoxin B1 (AFB1) was investigated. 3. Administration of AFB1 resulted in significant increases in serum alanine aminotransferase (ALT) and glutathione S-transferase (GST) levels and a signifi-cant decrease in aniline hydroxylase activity in liver microsomes. When T. sanguinea (5 ml/kg) was intraperitoneally administered to rats 12 h and 1 h before AFB1, liver injury was significantly reduced as seen in the decreased levels of serum ALT and serum GST. However, the decrease in aniline hydroxylase activity by AFB1 was not recovered but enhanced by T. sanguinea pre-treatment. 4. Kinetic analysis of cytochrome P450 activity of rat liver microsomes in vitro demonstrated that T. sanguinea inhibited aniline hydroxylase non-competitively suggesting depression of biotransformation of AFB1 to toxic metabolites. 5. The data indicate a hepatoprotective action of T. sanguinea against AFB1-induced liver injury.

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