Cluster Preface: Alkene Halofunctionalization

Synlett ◽  
2018 ◽  
Vol 29 (04) ◽  
pp. 399-400
Author(s):  
Jeffrey Johnston ◽  
Tomislav Rovis

Jeffrey N. Johnston is a 1992 graduate of Xavier University where he completed his B.S. Chemistry degree (Honors, summa cum laude). With summer research stints in medicinal, polymer, and inorganic pigment chemistry under his belt, he transitioned to synthetic organic chemistry at The Ohio State University where he worked with Leo Paquette for his graduate work (PhD 1997). He completed postdoctoral studies with ­David Evans at Harvard University (USA) and was supported by an NIH Postdoctoral Fellowship. His independent career began in 1999 at Indiana University, where he was promoted to Professor of Chemistry before moving to Vanderbilt University in 2006. He is currently a Stevenson Professor of Chemistry. The commitment of his students and postdoctoral scholars to the discovery and development of new reactions and reagents, particularly in enantioselective catalysis, have led to numerous honors, including the Cope Scholar Award, a Fellowship from the Japan Society for the Promotion of Science, a Swiss Chemical Society Lectureship, and an Eli Lilly Grantee Award. It was graduate student Mark Dobish's discovery of the chiral proton-catalyzed enantioselective iodolactonization reaction (J. Am Chem. Soc. 2012, 134, 6068) that began his group's exploits of alkene halofunctionalization reactions for the good of chemical synthesis. Tomislav Rovis was born in Zagreb in former Yugoslavia but was largely raised in southern Ontario, Canada. He earned his PhD degree at the University of Toronto (Canada) in 1998 under the direction of Professor Mark Lautens. From 1998–2000, he was an NSERC Postdoctoral Fellow at Harvard University (USA) with Professor David A. Evans. In 2000, he began his independent career at Colorado State University and was promoted in 2005 to Associate Professor and in 2008 to Professor. His group’s accomplishments have been recognized by a number of awards including an Arthur C. Cope Scholar, an NSF CAREER Award, a Fellow of the American Association for the Advancement of Science and a ­Katritzky Young Investigator in Heterocyclic Chemistry. In 2016, he moved to Columbia University where he is currently Professor of Chemistry.

Synlett ◽  
2021 ◽  
Vol 32 (02) ◽  
pp. 140-141
Author(s):  
Louis-Charles Campeau ◽  
Tomislav Rovis

obtained his PhD degree in 2008 with the late Professor Keith Fagnou at the University of Ottawa in Canada as an NSERC Doctoral Fellow. He then joined Merck Research Laboratories at Merck-Frosst in Montreal in 2007, making key contributions to the discovery of Doravirine (MK-1439) for which he received a Merck Special Achievement Award. In 2010, he moved from Quebec to New Jersey, where he has served in roles of increasing responsibility with Merck ever since. L.-C. is currently Executive Director and the Head of Process Chemistry and Discovery Process Chemistry organizations, leading a team of smart creative scientists developing innovative chemistry solutions in support of all discovery, pre-clinical and clinical active pharmaceutical ingredient deliveries for the entire Merck portfolio for small-molecule therapeutics. Over his tenure at Merck, L.-C. and his team have made important contributions to >40 clinical candidates and 4 commercial products to date. Tom Rovis was born in Zagreb in former Yugoslavia but was largely raised in southern Ontario, Canada. He earned his PhD degree at the University of Toronto (Canada) in 1998 under the direction of Professor Mark Lautens. From 1998–2000, he was an NSERC Postdoctoral Fellow at Harvard University (USA) with Professor David A. Evans. In 2000, he began his independent career at Colorado State University and was promoted in 2005 to Associate Professor and in 2008 to Professor. His group’s accomplishments have been recognized by a number of awards including an Arthur C. Cope Scholar, an NSF CAREER Award, a Fellow of the American Association for the Advancement of Science and a ­Katritzky Young Investigator in Heterocyclic Chemistry. In 2016, he moved to Columbia University where he is currently the Samuel Latham Mitchill Professor of Chemistry.


Synlett ◽  
2017 ◽  
Vol 28 (13) ◽  
pp. 1546-1547 ◽  
Author(s):  
Shannon Stahl ◽  
Tomislav Rovis

Shannon S. Stahl was an undergraduate at the University of Illinois at Urbana-Champaign, and a graduate student at Caltech (PhD, 1997), where he worked with Professor John Bercaw. He was an NSF postdoctoral fellow with Professor Stephen Lippard at Massachusetts Institute of Technology from 1997–1999. He is currently a Professor of Chemistry at the University of Wisconsin–Madison, where he began his independent career in 1999. His research group specializes in catalysis, with an emphasis on aerobic oxidation reactions and oxygen chemistry related to energy conversion. Tomislav Rovis was born in Zagreb in former Yugoslavia but was largely raised in southern Ontario, Canada. He earned his PhD degree at the University of Toronto (Canada) in 1998 under the direction of Professor Mark Lautens. From 1998–2000, he was an NSERC Postdoctoral Fellow at Harvard University (USA) with Professor David A. Evans. In 2000, he began his independent career at Colorado State University and was promoted in 2005 to Associate Professor and in 2008 to Professor. His group’s accomplishments have been recognized by a number of awards including an Arthur C. Cope Scholar, an NSF CAREER Award, a Fellow of the American Association for the Advancement of Science and a ­Katritzky Young Investigator in Heterocyclic Chemistry. In 2016, he moved to Columbia University where he is currently Professor of Chemistry.


Author(s):  
Tristan H. Lambert

Benjamin List at the Max-Planck-Institute in Mülheim reported (Angew. Chem. Int. Ed. 2013, 52, 3490) that the chiral phosphoric acid TRIP catalyzed the asymmet­ric SN2-type intramolecular etherification of 1 to produce tetrahydrofuran 2 with a selectivity factor of 82. The coupling of alkenol 3 with 4 to give the α-arylated tetra­hydropyran 5 via a method that combined gold catalysis and photoredox catalysis was disclosed (J. Am. Chem. Soc. 2013, 135, 5505) by Frank Glorius at Westfälische Wilhelms-Universität Münster. Mark Lautens at the University of Toronto reported (Org. Lett. 2013, 15, 1148) the conversion of cyclohexanedione 6 and phenylboronic acid to bicyclic ether 8 using rhodium catalysis in the presence of dienyl ligand 7. Propargylic ether 9 was found (Org. Lett. 2013, 15, 2926) by John P. Wolfe at the University of Michigan to undergo conversion to furanone 10 upon treatment with dibutylboron triflate and Hünig’s base followed by oxidation with hydrogen peroxide. Tomislav Rovis at Colorado State University demonstrated (Chem. Sci. 2013, 4, 1668) that the spirocyclic compound 13 could be prepared in enantioenriched form from 11 by a photoisomerization- coupled Stetter reaction using carbene catalyst 12. Antonio C. B. Burtoloso at the University of São Paulo reported (Org. Lett. 2013, 15, 2434) the conversion of ketone 14 to lactone 15 using samarium(II) iodide and methyl acrylate. The merger of diketone 16 and pyrone 17 in the presence of Amberlyst-15 to pro­duce (−)- tenuipyrone 18 was disclosed (Org. Lett. 2013, 15, 6) by Rongbiao Tong at the Hong Kong University of Science and Technology. Joanne E. Harvey at Victoria University of Wellington in New Zealand found (Org. Lett. 2013, 15, 2430) that tricy­clic ether 20 could be generated efficiently from dihydropyran 19 and pyrone 17 via a palladium-catalyzed double allylic alkylation cascade. Two rings and four stereocenters were generated in the construction of bicyclic ether 23 from dienol 21 and acetal 22 via a Lewis acid-mediated cascade, as reported (Org. Lett. 2013, 15, 2046) by Christine L. Willis at the University of Bristol.


2014 ◽  

Collection of abstracts from the sixth Annual Undergraduate Research Conference at the Interface of Biology and Mathematics. Plenary speakers: Joseph Tien, Associate Professor of Mathematics at The Ohio State University; and Jeremy Smith, Governor's Chair at the University of Tennessee and Director of the University of Tennessee/Oak Ridge National Lab Center for Molecular Biophysics.


Philosophy ◽  
2000 ◽  
Vol 75 (3) ◽  
pp. 329-329

Notes on ContributorsGilbert Ryle (1900–76)Taught at Christ Church, Oxford from 1924–45 and was Waynflete Professor of Metaphysics at Oxford University from 1945–68. His Concept of Mind (1949) is one of the classics of twentieth century philosophy.Jennifer NagelTeaches philosophy at the University of New Mexico and the University of Toronto.Philip KitcherProfessor of Philosophy at Columbia University. He has written books and articles on a variety of topics in the philosophy of science.Achille VarziAssociate Professor of Philosophy at Columbia University. His most recent works are An Essay in Universal Semantics and Parts and Places (with Roberto Casati).Neil CooperEmeritus Professor of Philosophy, University of Dundee. He is author of The Diversity of Moral Thinking. His contributions to Philosophy include ‘Two Concepts of Morality’ (January 1996) and ‘The Art of Philosophy’ (April 1991).Stephen R. L. ClarkProfessor of Philosophy, University of Liverpool. His most recent book is Biology and Christian Ethics (forthcoming, Cambridge University Press).D. GoldstickProfessor of Philosophy, University of Toronto. His earlier contributions to Philosophy include ‘The Welfare of the Dead’ (January 1988).Colin RadfordFormerly Research Professor of Philosophy, University of Kent. Now Emeritus (since 1996).Phil DoweLecturer in Philosophy at the University of Tasmania. He works on causation, time and chance. He has published a book on causation, Physical Causation (Cambridge University Press, 2000) and is currently working on a book on time travel called ‘Backwards Causation’.


What is reported in the following pages is an example of work achieved in a relatively short time by the co-operation of a sufficient number of institutions and individuals. The venue of this research was in the Andes, and the work was carried out in the winter 1921-1922, yet its organisation only commenced definitely in the early summer of 1921, when a group of British and American physiologists secured the support of the various universities or other institutions to which they were attached. This support was given in the most ungrudging way. It included the liberation from immediate duty of the members of the party, often at considerable inconvenience to those who remained at home, the loan of apparatus, the contribution of substantial funds, and a great body of goodwill, which was perpetually translating itself into increased efficiency of the work actually accomplished. The following collaborated in one or more of the ways indicated above:— The Department of Physical Chemistry of Harvard University. The Proctor Fund of Harvard University. The Elizabeth Thompson Fund. The Rockefeller Institute of Medical Research, New York City. Columbia University.—From a fund, to which contributions were made by Dr. Walter B. James, Mr. Cleveland H. Dodge, and a contributor who wishes to withhold his name, but to whom thanks are none the less due. The Royal Society of London. The Research Grant to the Physiological Department of the University of Toronto. The Moray Fund, Edinburgh. The Carnegie Fund, Edinburgh. Sir Robert Hadfield, Bart., F. R. S. Sir Peter Mackie, Bart.


2016 ◽  
Vol 1 (5) ◽  
pp. 4-12
Author(s):  
David P. Kuehn

This report highlights some of the major developments in the area of speech anatomy and physiology drawing from the author's own research experience during his years at the University of Iowa and the University of Illinois. He has benefited greatly from mentors including Professors James Curtis, Kenneth Moll, and Hughlett Morris at the University of Iowa and Professor Paul Lauterbur at the University of Illinois. Many colleagues have contributed to the author's work, especially Professors Jerald Moon at the University of Iowa, Bradley Sutton at the University of Illinois, Jamie Perry at East Carolina University, and Youkyung Bae at the Ohio State University. The strength of these researchers and their students bodes well for future advances in knowledge in this important area of speech science.


PEDIATRICS ◽  
1957 ◽  
Vol 19 (4) ◽  
pp. 715-717

The Ninth Annual Summer Clinics of The Children's Hospital in Denver, Colorado will be held June 24, 25, and 26, 1957. Designed for all physicians concerned with the care of children, the course will present recent advances in medical knowledge appropriate to the first few weeks of life, and will emphasize methods for the early recognition of disease, discuss emergency procedures of value, and outline successful programs of therapy. Guest faculty this year will be Dr. Stewart H. Clifford, Assistant Clinical Professor of Pediatrics, Harvard Medical School, Dr. H. William Clatworthy, Jr., Associate Professor of Pediatric Surgery, Ohio State University, and Dr. Edith L. Potter, Professor of Pathology, Department of Obstetrics and Gynecology, The University of Chicago.


2001 ◽  
Vol 82 (3) ◽  
pp. 234-235
Author(s):  
E. S. Valishin

Khabibulla Nurmukhametovich Amirov was born on May 18, 1901 in the village of Tat. Tashaevo of the Nurlatsky district of Tatarstan in a working peasant family. His early desire for knowledge prompted him to move to his brother in Chita as a child, where he graduated from the parish school of the 1st stage in 1916, and in 1923 from the parish school of the 2nd stage. Having shown outstanding performance, curiosity and a great thirst for knowledge over the years of study, after graduating from college, he was sent to continue his studies at the Medical Faculty of Kazan State University. From the very first days of his stay at the university, he takes up his studies with great zeal, paying great attention to a new and unfamiliar subject normal human anatomy. However, experiencing great financial difficulties, he was forced to interrupt his studies at the university. From 1924 to 1927, the young man worked as a nurse in the Zabulachno-Pletenevsky skin and venereological dispensary of the Tatnarkomzdrav, and only after the appointment of a special family scholarship, he was able to continue his studies.


2005 ◽  
Vol 24 (4) ◽  
pp. 163 ◽  
Author(s):  
Laura Tull

<span>In the fall of 2002, Ohio State University along with the University of Washington, the University of Western Australia, Washington State University, and Glasgow University entered into a development partnership with Innovative Interfaces. The goal was to develop a module to manage electronic resources, integrated into Innovative’s Millennium library system. The product, Electronic Resource Management (ERM), became available in 2004 and is based on the work of the Digital Library Federation Electronic Resources Management Initiative. This article focuses on one aspect of ERM, the integration of the module with the Web OPAC, and describes how the Ohio State University Libraries replaced a back-end database with ERM to support lists of electronic resources on their Web site.</span>


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