The Role of a Single Dose of Vancomycin in Reducing Clinical Sepsis in Premature Infants Prior to Removal of Peripherally Inserted Central Catheter: A Retrospective Study

2018 ◽  
Vol 35 (10) ◽  
pp. 990-993
Author(s):  
Lovya George ◽  
Michael Malloy ◽  
Rafael Fonseca ◽  
Vidit Bhargava

Objective Peripherally inserted central catheter (PICC) line removal is associated with bloodstream infections and clinical sepsis. We aim to investigate the role of a single prophylactic dose of vancomycin in decreasing the incidence of central line associated bloodstream infection associated with PICC removal. Methods A retrospective chart review of patients in the neonatal intensive care unit was conducted. Patients were divided into two study groups based on whether a single dose of vancomycin was administered (exposed) or not (nonexposed). The primary outcome measured was clinical sepsis with or without positive blood culture. Results The incidence of clinical sepsis in the exposed group was 7.3% compared with 6.3% in the nonexposed group (p-value: 0.7860). The incidence of culture-positive sepsis in the exposed group was 2.2% compared with 1.6% in the nonexposed group (p-value: 0.7673). The overall incidence of clinical and culture-positive sepsis in the subgroup with infants weighing <1,500 g and <32 weeks' gestational age was similar to the main study group. Conclusion Our data do not support routine vancomycin prophylaxis prior to PICC line removal in premature infants to prevent sepsis associated with PICC removal. However, a large randomized controlled trial is further needed to delineate these results.

2021 ◽  
pp. 097321792110076
Author(s):  
Abdah Hrfi ◽  
Mohammed H.A. Mohammed ◽  
Omar Tamimi

Cardiac tamponade as a result of pericardial effusion (PE) is a serious uncommon condition in the neonatal period. PE in such cases could be associated with hydrops fetalis, neonatal sepsis, metabolic diseases, or as a complication of percutaneous indwelling central catheter. 1 We are reporting a preterm baby, with low birth weight who developed large PE as a complication of total parenteral nutrition via a peripherally inserted central catheter, managed successfully with pericardiocentesis.


2013 ◽  
Vol 11 (8) ◽  
pp. 649
Author(s):  
N.D. Appleton ◽  
A. Corris ◽  
C. Edwards ◽  
A. Kenyon ◽  
C.J. Walsh

2019 ◽  
Vol 5 (02) ◽  
pp. 64-66
Author(s):  
Arvind Borde ◽  
Vivek Ukirde

Abstract Introduction A persistent left superior vena cava (SVC) is found in 0.3 to 0.5% of the general population. It is seen in up to 10% of the patients with a congenital cardiac anomaly, being the most common thoracic venous anomaly, and is usually asymptomatic. Being familiar with such anomaly could help clinicians avoid complications during the placement of central lines, Swan-Ganz catheters, peripherally inserted central catheter (PICC) lines, dialysis catheters, defibrillators, and pacemakers. Case Presentation We describe a case of persistent left SVC which was noted after placement of a PICC line. A 5-year-old male child was hospitalized for evaluation and management of leukemia. He required PICC line placement for chemotherapy. He was noted to have a persistent left SVC during the procedure under fluoroscopic guidance and subsequently correct placement of PICC line in right SVC. Discussion This anatomical variant can pose iatrogenic risks if the clinician does not recognize it. A central catheter that tracks down the left mediastinal border may also be in the descending aorta, internal thoracic vein, superior intercostal vein, pericardiophrenic vein, pleura, pericardium, or mediastinum. Conclusion Our case is significant because the patient was diagnosed with double SVC on table only followed by the placement of PICC line into the right SVC. This case strongly demonstrates the importance of knowing the thoracic venous anomalies.


2011 ◽  
Vol 16 (4) ◽  
pp. 218-220 ◽  
Author(s):  
J. Patricia Catudal ◽  
Elizabeth L. Sharpe

Abstract Peripherally Inserted Central Catheters (PICC) are essential in modern infusion therapy. We describe a case of a full-term infant with Trisomy 21, congenital cardiac anomalies and sepsis, where the PICC became malpositioned. Noninvasive repositioning strategies were successfully utilized through a team approach, which enabled this unstable infant to complete their therapy course without the undue stress of inserting a new PICC or requiring additional X-Rays or more invasive replacement procedures.


2017 ◽  
Vol 22 (1) ◽  
pp. 20-21
Author(s):  
Priyank Shah ◽  
Rahul Vasudev ◽  
Raja Pullatt ◽  
Fayez Shamoon

Abstract A 42-year-old woman with past medical history of intravenous drug abuse was admitted to hospital with fever and heart murmur. A peripherally inserted central catheter (PICC) was inserted because the patient had poor venous access. Transesophageal echocardiography was done to rule out infective endocarditis. The test showed thrombus attached to the PICC line. Thrombus arising from a catheter is known complication of PICCs. Classifications of right heart thromboembolism (RHTE) are based on morphology. Type A thrombi are highly mobile and may prolapse through the tricuspid valve. Conversely, type B thrombi are attached to the right atrial or ventricular wall and may originate in association with foreign bodies or in structurally abnormal chambers. RHTEs are associated with pulmonary embolism in approximately 4%–6% of cases and increase the 3-month mortality rate from 16% to 29%. On echocardiography, partial dissection of the superior vena cava (SVC) was also noted. This is a very rare complication of PICC. To the best of our knowledge this is the first reported case of PICC-induced thrombosis with partial dissection of SVC. The PICC line was removed and echocardiography postremoval did not show any thrombus. The patient remained asymptomatic without any signs of hemodynamically significant pulmonary embolism. SVC dissection was also managed conservatively. Use of central venous catheters in clinical practice is increasing but it is not a benign procedure. It may be associated with serious complications.


2006 ◽  
Vol 11 (3) ◽  
pp. 144-151 ◽  
Author(s):  
Gail A. Heckler-Medina

Abstract The author asks of the reader: Have you ever been called to start a peripheral intravenous (IV) catheter or place a peripherally inserted central catheter (PICC) in a child, and you wished someone else could do it? Performing vascular access procedures on children is considered by many one of the most stressful and difficult jobs. This article discusses the role of certified child life specialists (CCLSs) and some of the techniques used to assist children in coping with painful procedures as well as the necessity for proper assessment and pain management. The goal of this article is to eliminate the uncertainty of performing these procedures on pediatric patients. By making a few changes in your practice, one could dramatically increase successful outcomes and improve the overall quality of care provided to the patient.


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