Stress-induced changes in intestinal permeability in mice: Influence of STW 5

2019 ◽  
Author(s):  
P Aubert ◽  
J Chevalier ◽  
T Durand ◽  
A Bessard ◽  
O Kelber ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Induced Changes

Intestinal permeability in allergic rats: nerve involvement in antigen-induced changes

1993 ◽  
Vol 264 (4) ◽  
pp. G617-G623 ◽  
Author(s):  
S. E. Crowe ◽  
K. Soda ◽  
A. M. Stanisz ◽  
M. H. Perdue
Keyword(s):  
Intestinal Permeability ◽  
Fold Increase ◽  
Serum Levels ◽  
Baseline Period ◽  
Antigen Challenge ◽  
51Cr Edta ◽  
Neural Factors ◽  
Induced Changes ◽  
In Vivo Uptake

In vivo uptake of the probe 51Cr-labeled EDTA from the jejunum of egg albumin (EA)-sensitized rats was compared with controls at baseline and after intraluminal antigen challenge. Probe recovery in blood was 60-80% greater in sensitized animals during the baseline period, suggesting that sensitization resulted in increased intestinal permeability. Sensitized, but not control, rats demonstrated a 15-fold increase in 51Cr-EDTA uptake after intraluminal antigen; no change occurred with an unrelated protein. Macromolecular recovery was also enhanced in sensitized animals, since serum levels of immunoreactive EA were elevated 14-fold compared with controls. Antigen challenge was accompanied by biochemical (protease release) and morphological (reduced numbers) evidence of mast cell degranulation in sensitized rats. The neurotoxin tetrodotoxin (applied directly to ligated jejunal segments) inhibited EA-induced uptake of 51Cr-EDTA and antigen. In isolated jejunum from sensitized rats, tetrodotoxin reduced secretory responses to luminal, but not serosal, antigen. These results indicate that neural factors may influence the uptake of molecules from the gut lumen during intestinal anaphylaxis.

Effects of metronidazole and misoprostol on indomethacin-induced changes in intestinal permeability

1993 ◽  
Vol 38 (3) ◽  
pp. 417-425 ◽  
Author(s):  
Gareth R. Davies ◽  
Martin E. Wilkie ◽  
David S. Rampton
Keyword(s):  
Intestinal Permeability ◽  
Induced Changes

scholarly journals Estradiol prevented intestinal ischemia and reperfusion-induced changes in intestinal permeability and motility in male rats

Clinics ◽  
2021 ◽  
Vol 76 ◽  
Author(s):  
Fernanda Yamamoto Ricardo-da-Silva ◽  
Evelyn Thaís Fantozzi ◽  
Sara Rodrigues-Garbin ◽  
Helori Vanni Domingos ◽  
Ricardo Martins Oliveira-Filho ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Intestinal Ischemia ◽  
Male Rats ◽  
Ischemia And Reperfusion ◽  
Induced Changes

Misoprostol reduces indomethacin-induced changes in human small intestinal permeability

1989 ◽  
Vol 34 (3) ◽  
pp. 407-411 ◽  
Author(s):  
Ingvar Bjarnason ◽  
Paul Smethurst ◽  
Christopher G. Fenn ◽  
Carole E. Lee ◽  
Ian S. Menzies ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Small Intestinal ◽  
Induced Changes

STW 5 prevents stress-induced changes in intestinal permeability in mice in-vivo

2017 ◽  
Author(s):  
P Aubert ◽  
J Chevalier ◽  
T Durand ◽  
A Bessard ◽  
O Kelber ◽  
...  
Keyword(s):  
Intestinal Permeability ◽  
Induced Changes

Interpretation of irradiation-induced changes in electron diffractograms and images of extinction contours at low temperatures

1984 ◽  
Vol 42 ◽  
pp. 268-269
Author(s):  
E. Knapek ◽  
H. Formanek ◽  
G. Lefranc ◽  
I. Dietrich
Keyword(s):  
Low Temperatures ◽  
Carbon Films ◽  
Organic Crystals ◽  
Wide Spread ◽  
Lens System ◽  
Preparation Conditions ◽  
Thin Carbon ◽  
Electron Diffractograms ◽  
Diffraction Patterns ◽  
Induced Changes

A few years ago results on cryoprotection of L-valine were reported, where the values of the critical fluence De i.e, the electron exposure which decreases the intensity of the diffraction reflections by a factor e, amounted to the order of 2000 + 1000 e/nm2. In the meantime a discrepancy arose, since several groups published De values between 100 e/nm2 and 1200 e/nm2 /1 - 4/. This disagreement and particularly the wide spread of the results induced us to investigate more thoroughly the behaviour of organic crystals at very low temperatures during electron irradiation.For this purpose large L-valine crystals with homogenuous thickness were deposited on holey carbon films, thin carbon films or Au-coated holey carbon films. These specimens were cooled down to nearly liquid helium temperature in an electron microscope with a superconducting lens system and irradiated with 200 keU-electrons. The progress of radiation damage under different preparation conditions has been observed with series of electron diffraction patterns and direct images of extinction contours.

Drug Induced Changes in Cell Organelles

1968 ◽  
Vol 26 ◽  
pp. 110-111
Author(s):  
Sarah A. Luse
Keyword(s):  
Clinical Medicine ◽  
Cell Organelles ◽  
Riboflavin Deficiency ◽  
Drug Induced ◽  
New Era ◽  
Health And Disease ◽  
In The Beginning ◽  
Cellular Pathology ◽  
Induced Changes ◽  
The Impact

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.

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