Ruthenium-Catalyzed Synthesis of Pyrrolo[1,2-a]quinoxaline Derivatives from 1-(2-Aminophenyl)pyrroles and Sulfoxonium Ylides

Synlett ◽  
2020 ◽  
Vol 31 (12) ◽  
pp. 1205-1210 ◽  
Author(s):  
Guo-Sheng Huang ◽  
Xin-Feng Cui ◽  
Fang-Peng Hu ◽  
Xiao-Qiang Zhou ◽  
Zhen-Zhen Zhan
Keyword(s):  
Reaction Time ◽  
Functional Group ◽  
Reaction Pathway ◽  
Ambient Conditions ◽  
Step Method ◽  
Short Reaction Time ◽  
Quinoxaline Derivatives ◽  
One Step ◽  
Preliminary Study ◽  
Mechanism Of The Reaction

A ruthenium-catalyzed [5+1] annulation of 1-(2-aminophenyl)pyrroles with α-carbonyl sulfoxonium ylides is reported. This reaction provides a one-step method for synthesizing pyrrolo[1,2-a]quinoxaline derivatives under ambient conditions. The system proceeds with a short reaction time and a high functional-group tolerance. Notably, this divergent protocol tolerates β-keto sulfoxonium ylides and can be applied to α-ester sulfoxonium ylides. A preliminary study was made of the mechanism of the reaction, and a reaction pathway is proposed.

scholarly journals Efficient and Convenient Synthesis of 1,8-Dioxodecahydroacridine Derivatives Using Cu-Doped ZnO Nanocrystalline Powder as a Catalyst under Solvent-Free Conditions

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Sahar Mohseni Tavakkoli
Keyword(s):  
Reaction Time ◽  
Aromatic Aldehydes ◽  
Nanocrystalline Powder ◽  
Step Method ◽  
Short Reaction Time ◽  
Convenient Synthesis ◽  
Solvent Free Conditions ◽  
Aryl Amines ◽  
One Step ◽  
Doped Zno

A simple and convenient one-step method for synthesis of acridines and their derivatives from condensation of aromatic aldehydes, cyclic diketones, and aryl amines using Cu-doped ZnO nanocrystalline powder as a catalyst is reported. The present protocol provides several advantages such as good yields, short reaction time, easy workup, and simplicity in operation.

scholarly journals Flame-Retardant and Smoke Suppression Properties of Nano MgAl-LDH Coating on Bamboo Prepared by an In Situ Reaction

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Xiaoling Yao ◽  
Chungui Du ◽  
Yating Hua ◽  
Jingjing Zhang ◽  
Rui Peng ◽  
...  
Keyword(s):  
Reaction Time ◽  
Flame Retardant ◽  
Building Materials ◽  
Reaction Times ◽  
Step Method ◽  
In Situ Reaction ◽  
One Step ◽  
Double Hydroxide ◽  
Optimal Reaction

In recent years, bamboo has been widely used for building materials and household goods. However, bamboo is flammable, so a flame-retardant treatment for bamboo is urgently needed. In this work, nano MgAl-layered double hydroxide (MgAl-LDH) coated on bamboo, which was called MgAl-LB, was synthesized by an in situ one-step method. To determine the optimal in situ time, the effects of different reaction times on LDH growth on the bamboo surface and the flame retardancy of the MgAl-LBs were investigated. The SEM observations show that LDH growth on the surface of bamboo was basically saturated when the in situ reaction time was 24 h. Abrasion experiments show that MgAl-LDH coating has good abrasion resistance. The fire performance of the MgAl-LBs was evaluated by cone calorimeter tests, which indicated that the THR and TSP of the MgAl-LBs were significantly lower than those of untreated bamboo. Taking into account the energy consumption problem, determining the reaction time of 24 h is the optimal reaction time. Compared with untreated bamboo, the THR and TSP of MgAl-LB prepared at 24 h decreased by 33.3% and 88.9%, respectively.

Characteristics of Nanostructured TiO2 Prepared by One-Step Soaking Method for Photovoltaic Application

2014 ◽  
Vol 705 ◽  
pp. 3-7
Author(s):  
Mi Sun Park ◽  
Shi Joon Sung ◽  
Dae Hwan Kim
Keyword(s):  
Solar Cell ◽  
Reaction Time ◽  
Solar Cell Device ◽  
Flat Structure ◽  
Substrate Orientation ◽  
Short Reaction Time ◽  
Photovoltaic Application ◽  
One Step ◽  
Inorganic Semiconductor ◽  
Photovoltaic Characteristics

Nanostructured TiO2 films were prepared by a one-step soaking method, which has many advantages, such as simple fabrication, a short reaction time, and fast growth. We have investigated the growth of TiO2 films by the substrate orientation of the soaking method, which had an effect on the nanostructure of the TiO2 films. The TiO2 films prepared by this method had various structures: particulate-flat structure and sphere-flat structure. To determine the effect of the nanostructure of TiO2 films on the photovoltaic characteristics of solar cells, solar cell devices using the inorganic semiconductor Sb2S3 as a sensitizer were fabricated by chemical bath deposition (CBD). Our solar cell device, using TiO2 film with a sphere-flat structure as a photoelectrode, exhibited JSC, VOC, FF, and η values of 11.82 mA / cm2, 0.49 V, 30.27 %, and 1.74 %, respectively.

Synthesis of the Carboxyl and Pyridine Functional Ionic Liquids

2014 ◽  
Vol 513-517 ◽  
pp. 246-250 ◽  
Author(s):  
Ying Xiong ◽  
Min Yang
Keyword(s):  
Ionic Liquids ◽  
Reaction Time ◽  
Anion Exchange ◽  
Room Temperature ◽  
Exchange Resin ◽  
Anion Exchange Resin ◽  
Maximum Yield ◽  
Step Method ◽  
Strong Base ◽  
One Step

The effects of different solvents on synthesis of base functional ionic liquid, butyl pyridinium hydroxide ([bPy]OH), from butyl pyridinium bromine ([bPy]Br) were investigated systematically using KOH/NaOH as the base agent and strong base anion exchange resin. The results showed that the yield of [bPy]OH achieved 35% with the molar ratio of 1:1.1 ([bPy]Br to NaOH) using dichloromethane under room temperature. With isopropanol and 8 h of the reaction time, the yield could reach 88% with byproducts. The yield of 97% without byproduct was achieved by using strong base anion exchange resin in column chromatography static reaction for 0.25 h. The yield of carboxyl and pyridine functional ionic liquids based on neutralization method, exchange method and one-step method were compared and the results showed that the one-step method possessed the maximum yield of 88% with 3 h of the reaction time at room temperature.

scholarly journals Highly Efficient Recyclable Sol Gel Polymer Catalyzed One Pot Difunctionalization of Alkynes

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 1879
Author(s):  
Justin Domena ◽  
Carlos Chong ◽  
Qiaxian Johnson ◽  
Bhanu Chauhan ◽  
Yalan Xing
Keyword(s):  
Reaction Time ◽  
Room Temperature ◽  
Functional Group ◽  
Sol Gel ◽  
One Pot ◽  
Short Reaction Time ◽  
Metal Free ◽  
Highly Efficient

Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellent yields, regioselectivity, functional group compatibility, and recyclability. We have observed that both aromatic and aliphatic alkynes can be converted to α,α-dihalogenated ketones in the presence of polymer P1 under metal-free conditions at room temperature within a short reaction time.

Ultrasonic-assisted biodiesel production from waste cooking oil over novel sulfonic functionalized carbon spheres derived from cyclodextrin via one-step: a way to produce biodiesel at short reaction time

RSC Advances ◽  
2015 ◽  
Vol 5 (68) ◽  
pp. 55252-55261 ◽  
Author(s):  
Panya Maneechakr ◽  
Jittima Samerjit ◽  
Surachai Karnjanakom
Keyword(s):  
Catalytic Activity ◽  
Reaction Time ◽  
Waste Cooking Oil ◽  
Biodiesel Production ◽  
High Catalytic Activity ◽  
Carbon Spheres ◽  
Short Reaction Time ◽  
Cooking Oil ◽  
Ultrasonic Assisted ◽  
One Step

A novel sulfonated carbon derived from cyclodextrin showed high catalytic activity for the ultrasonic-assisted transesterification of waste cooking oil.

scholarly journals One-Step Synthesis of Hydroxysodalite Using Natural Bentonite at Moderate Temperatures

Minerals ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 521 ◽  
Author(s):  
Bo Liu ◽  
Hongjuan Sun ◽  
Tongjiang Peng ◽  
Qian He
Keyword(s):  
Reaction Time ◽  
Reaction Temperature ◽  
Chemical Reactivity ◽  
Moderate Temperature ◽  
Water Bath ◽  
Degree Of Crystallinity ◽  
Molar Ratio ◽  
Step Method ◽  
One Step ◽  
Si Content

Ca-bentonite was used as the feedstock material for the synthesis of hydroxysodalite due to its high Al, Si content, good chemical reactivity, and natural abundance. A one-step method is proposed here to fabricate hydroxysodalite in a water bath at moderate temperature. The effects of the Na/Si molar ratio, Si/Al molar ratio, reaction time, and reaction temperature on the synthesis of hydroxysodalite have been systematically investigated here. The crystallizing phases and morphology of the synthetic products were characterized using X-ray diffraction (XRD) and scanning electron microscopy (SEM), respectively. The results showed that the Na/Si molar ratio and reaction temperature both played important roles in controlling the degree of crystallinity of the synthetic hydroxysodalite. The Si/Al molar ratio and reaction time both affect the purity of the synthetic hydroxysodalite. Optimum conditions for synthesizing hydroxysodalite using a one-step water-bath method at moderate temperature are as follows: a Na/Si molar ratio of 12, a Si/Al molar ratio of 1.0, a reaction temperature of 90 °C, and a reaction time of 12 h.

scholarly journals Gold(III) Aryl Complexes as Reagents for Constructing Hybrid Peptide-Based Assemblies via Cysteine S-Arylation

2020 ◽  
Author(s):  
Julia M. Stauber ◽  
Arnold L. Rheingold ◽  
Alexander Spokoyny
Keyword(s):  
Functional Group ◽  
Structural Complexity ◽  
Organometallic Complexes ◽  
Hybrid Peptide ◽  
Step Method ◽  
Aryl Complexes ◽  
One Step ◽  
Rapid Reaction ◽  
Peptide Functionalization

<p>Organometallic complexes have recently gained attention as competent bioconjugation reagents capable of introducing a diverse array of substrates to biomolecule substrates. Here, we detail the synthesis and characterization of an aminophosphine-supported Au(III) platform that provides rapid and convenient access to a wide array of peptide-based assemblies via cysteine S-arylation. This strategy results in the formation of robust C‒S covalent linkages and is an attractive method for the modification of complex biomolecules due to the high functional group tolerance, chemoselectivity, and rapid reaction kinetics associated with these arylation reactions. This work expands upon existing metal-mediated cysteine arylation by introducing a class of air-stable organometallic complexes that serve as competent bioconjugation reagents enabling the synthesis of conjugates of higher structural complexity including macrocyclic stapled and bicyclic peptides, as well as a peptide-functionalized multivalent hybrid nanocluster. This organometallic-based approach provides a convenient, one-step method of peptide functionalization and macrocyclization, and has the potential to contribute to efforts directed towards developing efficient synthetic strategies of building new and diverse hybrid peptide-based assemblies of high complexit<br></p>

scholarly journals Gold(III) Aryl Complexes as Reagents for Constructing Hybrid Peptide-Based Assemblies via Cysteine S-Arylation

2020 ◽  
Author(s):  
Julia M. Stauber ◽  
Arnold L. Rheingold ◽  
Alexander Spokoyny
Keyword(s):  
Functional Group ◽  
Structural Complexity ◽  
Organometallic Complexes ◽  
Hybrid Peptide ◽  
Step Method ◽  
Aryl Complexes ◽  
One Step ◽  
Rapid Reaction ◽  
Peptide Functionalization

<p>Organometallic complexes have recently gained attention as competent bioconjugation reagents capable of introducing a diverse array of substrates to biomolecule substrates. Here, we detail the synthesis and characterization of an aminophosphine-supported Au(III) platform that provides rapid and convenient access to a wide array of peptide-based assemblies via cysteine S-arylation. This strategy results in the formation of robust C‒S covalent linkages and is an attractive method for the modification of complex biomolecules due to the high functional group tolerance, chemoselectivity, and rapid reaction kinetics associated with these arylation reactions. This work expands upon existing metal-mediated cysteine arylation by introducing a class of air-stable organometallic complexes that serve as competent bioconjugation reagents enabling the synthesis of conjugates of higher structural complexity including macrocyclic stapled and bicyclic peptides, as well as a peptide-functionalized multivalent hybrid nanocluster. This organometallic-based approach provides a convenient, one-step method of peptide functionalization and macrocyclization, and has the potential to contribute to efforts directed towards developing efficient synthetic strategies of building new and diverse hybrid peptide-based assemblies of high complexit<br></p>

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