Effect of Music on the Efficiency of Performing a Microsurgical Arterial Anastomosis: A Prospective Randomized Study

Abstract Introduction Music is commonly played in operating rooms. Because microsurgery demands utmost concentration and precise motor control, we conducted the present study to investigate a potentially beneficial impact of music on performing a microsurgical anastomosis. Materials and Methods We included a novice group (15 inexperienced medical students) and a professional group (15 experienced microsurgeons) in our study. Simple randomization was performed to allocate participants to the music-playing first or music-playing second cohort. Each participant performed two end-to-end anastomoses on a chicken thigh model. Participant demographics, their subjective preference for work environment (music/no music), and time to completion were noted. The performance of the participants was assessed using the Stanford Microsurgery and Resident Training (SMaRT) scale by an independent examiner, and the final anastomoses were evaluated according to the anastomosis lapse index. Results Listening to music had no significant effect on time to completion, SMaRT scale, and anastomosis lapse index scores in both novice and professional cohorts. However, the subjective preference to work while listening to music correlated with high SMaRT scale scores within the professional cohort (p = 0.044). Conclusion Playing their preferred music in the operating room improves the performance scores of surgeons, but only if they subjectively appreciate working with background music.

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Effect of Epidural Analgesia with Ambulation on Labor Duration

Anesthesiology ◽

10.1097/00000542-200110000-00012 ◽

2001 ◽

Vol 95 (4) ◽

pp. 857-861 ◽

Cited By ~ 43

Author(s):

Manuel C. Vallejo ◽

Leonard L. Firestone ◽

Gordon L. Mandell ◽

Francisco Jaime ◽

Sandra Makishima ◽

...

Keyword(s):

Epidural Analgesia ◽

Randomized Study ◽

Mode Of Delivery ◽

Vena Cava ◽

Cervical Dilatation ◽

Fetal Head ◽

Chi Square ◽

Labor Duration ◽

Nulliparous Women ◽

Scale Scores

Background Ambulatory epidural analgesia (AEA) is a popular choice for labor analgesia because ambulation reportedly increases maternal comfort, increases the intensity of uterine contractions, avoids inferior vena cava compression, facilitates fetal head descent, and relaxes the pelvic musculature, all of which can shorten labor. However, the preponderance of evidence suggests that ambulation during labor is not associated with these benefits. The purpose of this study is to determine whether ambulation with AEA decreases labor duration from the time of epidural insertion to complete cervical dilatation. Methods In this prospective, randomized study, 160 nulliparous women with AFA were randomly assigned to one of two groups: AEA with ambulation and AEA without ambulation. AEA blocks were initiated with 15-20 ml ropivacaine (0.07%) plus 100 microg fentanyl, followed by a continuous infusion of 0.07% ropivacaine plus 2 microg/ml fentanyl at 15-20 ml/h. Maternal measured variables included ambulation time, time from epidural insertion to complete dilatation, stage II duration, pain Visual Analogue Scale scores, and mode of delivery. APGAR scores were recorded at 1 and 5 min. Results are expressed as mean +/- SD or median and analyzed using the t test, chi-square, or the Mann-Whitney test at P < or = 0.05. Results The ambulatory group walked 25.0 +/- 23.3 min, sat upright 40.3 +/- 29.7 min, or both. Time from epidural insertion to complete dilatation was 240.9 +/- 146.1 min in the ambulatory group and 211.9 +/- 133.9 min in the nonambulatory group (P = 0.206). Conclusion Ambulatory epidural analgesia with walking or sitting does not shorten labor duration from the time of epidural insertion to complete cervical dilatation.

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Can Geriatric Psychiatry Patients Complete Symptoms Self-Reports Using Tablets? A Randomized Study

Canadian Geriatrics Journal ◽

10.5770/cgj.20.282 ◽

2017 ◽

Vol 20 (3) ◽

pp. 112-119

Author(s):

Ghizlane Moussaoui ◽

Ching Yu ◽

Vincent Laliberté ◽

Dominique Elie ◽

Artin A. Mahdanian ◽

...

Keyword(s):

Psychiatric Symptoms ◽

Randomized Study ◽

Symptom Assessment ◽

Geriatric Psychiatry ◽

Brief Symptom Inventory ◽

Self Report ◽

Time To Completion ◽

Patient Health ◽

Adult Psychiatry ◽

Inpatient Group

BackgroundWith our aging population and limited number of geriatric psychiatrists, innovations must be made in order to meet the growing demands for geriatric psychiatry services. Emerging technologies could greatly improve access to care and systematic data collection.MethodsThis randomized study compared completion rates and time to completion (primary outcomes) when using iPad technology vs. traditional paper forms to complete self-report psychiatric symptoms. Geriatric psychiatry outpatients (n = 72) and adult psychiatry inpatients (n = 50) were recruited to complete the Brief Symptom Inventory (BSI-53), the Activities of Daily Living (ADL), and Patient Health Questionnaire (PHQ-9) questionnaires.ResultsGeriatric psychiatry outpatients completed the iPad and paper questionnaires at similar rates (91.7% vs. 97.2%, Fisher’s Exact p = .61). In two-way ANOVA, including patients aged ≥ 60 (n = 85), outpatient status (F(1,81) = 4.48, p = .037) and iPad format (F (1,81) = 8.96, p = .04) were associated with a shorter time to completion. The effect of questionnaire formats was especially prominent in the inpatient group on time to completion.ConclusionsOlder adults with mental illness demonstrate a similar ability to complete self-report questionnaires whether iPads or paper forms. iPad questionnaires may even require less time to complete in geriatric psychiatry inpatients. Patients also found iPad questionnaires to be easy to use and read. Tablets could potentially be used for psychiatric symptom assessment for clinical, research, and population health purposes.

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Randomized study of digital single-operator cholangioscope compared to fiberoptic single-operator cholangioscope in a novel cholangioscopy bench model

Endoscopy International Open ◽

10.1055/a-0584-6458 ◽

2018 ◽

Vol 06 (07) ◽

pp. E851-E856 ◽

Cited By ~ 9

Author(s):

Raj Shah ◽

Horst Neuhaus ◽

Mansour Parsi ◽

D. Reddy ◽

Douglas Pleskow

Keyword(s):

Image Quality ◽

Randomized Study ◽

Image Resolution ◽

Ease Of Use ◽

Wide Field ◽

Time To Completion ◽

Wide Field Of View ◽

High Image Resolution ◽

Single Operator ◽

Superior Image Quality

Abstract Background and study aims Cholangiopancreatoscopy is utilized for diagnosis and therapy of pancreaticobiliary disorders. a fully-disposable, digital, single-operator cholangioscope (DSOC) was developed with high image resolution and wide field-of-view. This bench study compared the new DSOC to the previous semi-disposable, fiber-optic cholangioscope (FSOC) prior to the clinical availability of the DSOC system. Methods Five experts performed one practice run followed by randomized runs comparing DSOC to FSOC in a biliary tract model consisting of three fixed left-intrahepatic tracts (LIHD), and variable common bile duct (CBD) and right-intrahepatic tracts (RIHD) with seven total lesions in multiple configurations. Timed runs aimed to visualize and target each lesion using miniature biopsy forceps. Definitions: visual success, visualizing targets; targeting success, touching target with forceps; complete run, touching seven targets within 20 minutes. Image quality, ease-of-use, and time to completion were recorded. Results Thirty-seven evaluable runs (20 DSOC, 17 FSOC) were completed. DSOC was superior to FSOC in Visual (99 % vs. 67 %, P < 0.001) and targeting success (6.6 vs. 4.5, P = 0.009), proportion of complete runs (13 /20 vs. 0 /17, P < 0.001) and time of run (10.1 min vs. 15.4 min, P < 0.001). For fixed LIHD, DSOC achieved higher targeting success compared to FSOC (2.6 vs. 1.1, P < 0.001) with no difference in RIHD and CBD targets (4.0 vs. 3.4, P = 0.39). Investigators reported superior image quality and ease-of-use with DSOC. Conclusions In this model, DSOC performed superiorly to FSOC in image quality, visualization, and maneuverability. The model could potentially be utilized for training endoscopists less experienced with cholangiopancreatoscopy.

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Randomized study of antibodies to IFN-g and TNF-a in secondary progressive multiple sclerosis

Multiple Sclerosis Journal ◽

10.1177/135245850100700502 ◽

2001 ◽

Vol 7 (5) ◽

pp. 277-284 ◽

Cited By ~ 7

Author(s):

S Skurkovich ◽

A Boiko ◽

I Beliaeva ◽

A Buglak ◽

T Alekseeva ◽

...

Keyword(s):

Multiple Sclerosis ◽

Controlled Trial ◽

Randomized Study ◽

Progressive Multiple Sclerosis ◽

Double Blind ◽

Secondary Progressive ◽

Number Of Patients ◽

Scale Scores ◽

Term Administration ◽

Group A

Studies of cytokines in multiple sclerosis (MS) have shown that immune mechanisms connected with disturbance of the synthesis of cytokines probably play critical roles in the initiation and prolongation of MS. In a double-blind, placebo-controlled trial, 45 patients with active secondary progressive MS were randomized to three groups of 15 patients, each receiving a short course of antibodies to IFN-g, to tumor necrosis factor (TNF)-a, or a placebo. After 12 months with analysis of disability (Expanded Disability Status Scale scores), accompanied by interval determinations of lymphocyte subpopulations, cytokine production levels, MRI, and evoked potentials, it was found that only patients who received antibodies to IFN-g showed statistically significant improvement compared to the placebo group-a significant increase in the number of patients without confirmed disability progression. This was supported by MRI data (a decrease in the number of active lesions) and systemic changes in cytokine status (a decrease in IL-1b, TNF-a, and IFN-g concentrations in supernatants of activated blood cells of these MS patients and an increase in TGF-b production). Neutralization of IFN-g could be a new approach to treating secondary progressive MS. Long-term administration of humanized monoclonal antibodies to IFN-g and simultaneous use of antibodies to IFN-g together with IFN-b products are planned.

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Influence of paroxetine and hydroxyzine hydrochloride therapy on anxiety-depressive disorders and platelet serotonin level in CAD patients

Arterial’naya Gipertenziya (Arterial Hypertension) ◽

10.18705/1607-419x-2012-18-6-554-559 ◽

2012 ◽

Vol 18 (6) ◽

pp. 554-559

Author(s):

S. N. Kozlova ◽

A. V. Golubev ◽

Y. S. Krylova ◽

E. V. Shlyakhto ◽

N. G. Neznanov ◽

...

Keyword(s):

Depressive Disorders ◽

Randomized Study ◽

Anxiety And Depression ◽

Serotonin Level ◽

Comorbid Anxiety ◽

Platelet Serotonin ◽

Scale Scores ◽

Icd 10 ◽

Artery Disease ◽

Design And Methods

Objective. Open, comparative, randomized study of efficiency, safety and assessment of influence of paroxetine and hydroxyzine hydrochloride therapy on platelet serotonin level in patients with coronary artery disease (CAD) and comorbid anxiety-depressive disorders were examined. Design and methods. We included 40 patients with chronic CAD and comorbid anxiety-depressive disorders, confirmed according to ICD-10. Patients with score more than 18 by Hamilton’s scale of anxiety and depression were enrolled. Results. We observed significant decrease Hamilton’s scale scores after 4 weeks of treatment, and after 8 weeks of treatment the reduction reached 50 %. Side effects were registered in both groups and quickly passed after the drug withdrawal. Platelet serotonin level decreased significant during paroxetine therapy. Conclusion. Treatment by paroxetine and hydroxyzine hydrochloride was associated with high anti-anxiety and anti-depressive activity. Use of paroxetine was associated with significant reduction of platelet serotonin level.

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MP-15.05: Comparison of outcome in renal transplant recipients with respect to arterial anastomosis: the internal versus the external iliac artery - a prospective randomized study

Urology ◽

10.1016/j.urology.2007.06.065 ◽

2007 ◽

Vol 70 (3) ◽

pp. 118

Author(s):

A. Bahlooli ◽

M. Amjadi ◽

A. Zomorrodi ◽

H. Barhaghi

Keyword(s):

Renal Transplant ◽

Iliac Artery ◽

Randomized Study ◽

External Iliac Artery ◽

Prospective Randomized Study ◽

Renal Transplant Recipients ◽

Transplant Recipients ◽

Arterial Anastomosis

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Comparison of mannitol regimens in patients with severe head injury undergoing intracranial monitoring

Journal of Neurosurgery ◽

10.3171/jns.1986.65.6.0820 ◽

1986 ◽

Vol 65 (6) ◽

pp. 820-824 ◽

Cited By ~ 103

Author(s):

Harold P. Smith ◽

David L. Kelly ◽

Joe M. McWhorter ◽

Darlene Armstrong ◽

Rayetta Johnson ◽

...

Keyword(s):

Severe Head Injury ◽

Head Injuries ◽

Randomized Study ◽

Similar Treatment ◽

Content Type ◽

Group I ◽

Head Injured ◽

Scale Scores ◽

Injured Patients ◽

Fine Print

✓ Eighty patients sustaining head injuries and presenting with Glasgow Coma Scale scores of 8 or less were entered into a prospective randomized study to assess the benefit of intracranial pressure (ICP) monitoring with two regimens of mannitol administration. Group I was treated with mannitol for ICP elevations greater than 25 mm Hg, while Group II received empirical mannitol therapy irrespective of ICP readings. No statistically significant differences in mortality rate or neurological outcome were demonstrated between the two groups. These results are comparable to those of several published series of head-injured patients receiving similar treatment from 1977 to 1982. However, those series must be reassessed in light of recently published studies with treatment initiated at lower levels of ICP.

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