The Association between Serum Sodium Levels and Febrile Seizures Recurrence: Is the Degree of Hyponatremia a Risk Factor?

2021 ◽  
Author(s):  
Esma Keleş Alp ◽  
Ahmet Midhat Elmacı
Keyword(s):  
Serum Sodium ◽  
Medical Records ◽  
Febrile Seizure ◽  
Serum Sodium Level ◽  
Febrile Seizures ◽  
Lower Sensitivity ◽  
Operating Characteristics ◽  
Serum Electrolyte ◽  
Optimal Cutoff ◽  
Characteristics Analysis

AbstractFebrile seizures are common disorders in childhood. We evaluated the serum electrolyte levels and the associated factors in children with single and recurrent febrile seizures in 24 hours period of hospitalization. The medical records of children who were clinically diagnosed with febrile seizures and hospitalized were retrospectively revealed and analyzed. Data were collected for children aged 1 to 6 years including demographic parameters and serum electrolyte levels. A total of 244 children were enrolled in the study in which 209 were diagnosed with single febrile seizures and 35 of them with recurrent febrile seizures. Serum sodium levels were significantly lower in children with recurrent febrile seizure (138.5 ± 2.38 and 134.2 ± 3.55, p < 0.001). Correlation analysis revealed that mild hyponatremia is associated with recurrence of febrile seizure within 24 hours. However, receiver-operating characteristics analysis for hyponatremia showed lower sensitivity (50.3%) and specificity (43.1%) values for optimal cutoff value of 133.5 mmol/L of serum sodium level. Our study suggested that serum sodium levels were significantly lower in children with recurrent febrile seizures. However, because of its lower sensitivity and specificity values, mild hyponatremia cannot be used as an indicator for febrile seizure recurrence.

scholarly journals Serum Sodium Levels Predict the Recurrence of Febrile Seizure within 24 Hours

2019 ◽  
Author(s):  
Jatuporn Duangpetsang
Keyword(s):  
Family History ◽  
Serum Sodium ◽  
Medical Records ◽  
Febrile Seizure ◽  
Serum Sodium Level ◽  
Febrile Seizures ◽  
P Value ◽  
Seizure Recurrence ◽  
History Of

Objective: Febrile seizure is a common disorder in children that occurs in 2.5% of children 6-60 months of age. The study was conducted to ascertain the role of serum sodium as a predictor of seizure recurrence within the same febrile illness.Material and Methods: A retrospective study was conducted in children with febrile seizures who were admitted to Kaengkhro Hospital between 1 January 2014 and 31 December 2017. The data collected from medical records included age, gender, serum sodium level, body temperature, duration of fever, and family history of febrile seizures.Results: Two hundred ten children were diagnosed with febrile seizures; 190 had a single febrile seizure and 20 had recurrent febrile seizures. Mean±standard deviation ages of children with a single febrile seizure and recurrent febrile seizures were 22.95 ± 0.95 and 22.34 ± 0.89 months, respectively. Serum sodium levels in children with recurrent seizures within 24 hours (130.80 mmol/L) were significantly lower than in children with a single febrile seizure (132.37 mmol/L, p-value=0.02). A family history of febrile seizures was significant for predicting recurrent seizures within 24 hours (p−value= 0.006).Conclusion: Serum sodium levels predict the recurrence of febrile seizure within 24 hours.

scholarly journals Serum Sodium Level on the Recurrence of Febrile Seizure within the Same Febrile Illness-Experience in a District Level Hospital

2019 ◽  
Vol 32 (1) ◽  
pp. 39-45
Author(s):  
M Luthfor Rahman ◽  
Belal Hossain ◽  
Belal Uddin ◽  
Sanaul Haq Mia
Keyword(s):  
Serum Sodium ◽  
Febrile Seizure ◽  
Sodium Level ◽  
Serum Sodium Level ◽  
Central Nervous System Infection ◽  
Febrile Illness ◽  
Febrile Seizures ◽  
Febrile Episode ◽  
Cross Sectional ◽  
Recurrent Seizure

Introduction: Febrile convulsion is the most common seizure disorder in the pediatric age group. It occurs in 2-5% of children. A febrile seizure is a seizure accompanied by fever (temperature 100.4°F or 38°C by any method), without central nervous system infection, that occurs in infants and children 6 through 60 months of age. Aim: The study was conducted to see the effect of serum sodium level on the recurrence of febrile seizure during the same febrile illness. Materials and Method: A cross-sectional descriptive study which enrolled 65 children admitted with febrile seizures at 100 bed district hospital, Naogaon. They were divided in to two groups, those with a single seizure and the rest were children with more than one seizures. Serum sodium levels were estimated after stabilization of patients. The probability of recurrent febrile seizures and serum sodium level was analyzed. Results: Hyponatremia (serum sodium <135 mmol/l) was seen in 12(18.5%) of 65 children and the remaining 81.5% children had normal serum sodium level (serum sodium 135-145 mmol/l). Among the hyponatremia group all children developed more than one seizure during the same febrile episode. The mean serum sodium level in patients with single and recurrent seizure was 138.48±2.17mmol/l and 135.27±3.11mmol/(P<0.001). The relationship between the probability of a recurrent seizure and serum sodium level is statistically highly significant. Conclusion: Estimation of the seum sodium in children with febrile seizures help in deciding for admission in hospital as well as to predict seizure recurrence within the same febrile episode. TAJ 2019; 32(1): 39-45

scholarly journals Gambaran Elektrolit dan Gula Darah Pasien Kejang Demam yang Dirawat di Bangsal Anak RSUP Dr. M. Djamil Periode Januari 2010 - Desember 2012

2013 ◽  
Vol 2 (3) ◽  
pp. 127
Author(s):  
Khairunnisa Imaduddin ◽  
Iskandar Syarif ◽  
Rahmatini Rahmatini
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Serum Sodium ◽  
Serum Potassium ◽  
Febrile Seizure ◽  
Fasting Blood Glucose ◽  
Febrile Seizures ◽  
Normal Serum ◽  
Fasting Blood Glucose Level

AbstrakKejang demam merupakan kelainan neurologik yang paling sering dijumpai pada anak. Kejang demam merupakan bangkitan kejang yang terjadi pada saat anak demam akibat proses ekstrakranial. Kejang demam terjadi pada suhu rektal >38 C. Penelitian ini bertujuan untuk mengetahui gambaran elektrolit dan gula darah pada pasien kejang demam yang dirawat di bangsal anak RSUP Dr. M. Djamil. Penelitian ini merupakan penelitian deskriptif menggunakan metode retrospektif dengan mengambil data dari bagian rekam medis RSUP Dr. M.Djamil. Sampel penelitian adalah seluruh pasien kejang demam yang dirawat di bangsal anak RSUP Dr. M. Djamil periode Januari 2010 - Desember 2012 yang memenuhi kriteria inklusi. Dari 173 kasus kejang demam, terdapat 51 kasus yang memenuhi kriteria sampel penelitian. Sebagian besar sampel merupakan kejang demam pertama (76,5%). Kejang demam kompleks didapatkan sebesar 64,7%. Kasus kejang demam terbanyak terjadi pada kelompok usia ≥6 bulan < 2 tahun yaitu sebesar 51%. Kejang demam lebih sering terjadi pada laki-laki daripada perempuan dengan perbandingan 1,4:1. Penelitian menunjukkan penurunan nilai natrium serum (n=46, 80,4%), dan kalsium serum (n=30, 63,3%), nilai kalium serum normal (n=46, 76,1%), dan peningkatan nilai gula darah sewaktu (n=45, 57,8%). Pada pasien kejang demam ditemukan penurunan nilai natrium dan kalsium serum, nilai kalium serum normal, dan peningkatan nilai gula darah sewaktu. Diharapkan penelitian yang akan datang memiliki jumlah sampel yang lebih besar untuk mengetahui gambaran elektrolit dan gula darah pada pasien kejang demam.Kata kunci: kejang demam, natrium serum, kalium serum, kalsium serum, gula darah sewaktuAbstractFebrile seizure is the most common neurological disorder found in children. Febrile seizure is seizure that occurs while the children have fever caused by extracranial process. It occurs in rectal temperature >38 C. This research aim to describe the electrolytes and blood glucose in patients with febrile seizure who were treated at the pediatric's ward of Dr. M. Djamil general hospital. From 173 cases of febrile seizures, there are 51 cases that meet the criterias of the research sample. Most of the research samples are first febrile seizure (76.5%). Complex febrile seizure occurred in 64.7%. Most cases of febrile seizures occurred in the age group ≥ 6 months - <2 years, about 51%. Febrile seizures are more common in males than females with the ratio 1.4:1. The research shows decrease serum sodium (n = 46, 80.4%), and serum calcium (n = 30, 63.3%), normal serum potassium (n = 46, 76.1%), and increase non-fasting blood glucose level (n = 45, 57.8%). The patients with febrile seizure show decrease serum sodium and calcium, normal serum potassium, and increase non-fasting blood glucose level. Expected future studies have a lot of samples in determining the electrolytes and blood glucose in patients with febrile seizure.Keywords: febrile seizures, serum sodium, serum potassium, serum calcium, non-fasting blood glucose level

Letters to the Editor

PEDIATRICS ◽  
1980 ◽  
Vol 65 (3) ◽  
pp. 680-680
Author(s):  
Karin B. Nelson ◽  
Jonas H. Ellenberg
Keyword(s):  
Medical Records ◽  
Febrile Seizure ◽  
Febrile Seizures ◽  
Sources Of Information ◽  
Letters To The Editor ◽  
Drug Usage ◽  
Medical Experience ◽  
History Of

The sources of information concerning treatment of febrile seizures in our recent study were medical records written at the time of treatment of an initial or later febrile seizure, the nine scheduled interval histories, and a full history of the child's medical experience recorded when registrants reached the age of 7 years. However, information on drug usage, unlike the remainder of the information utilized in these studies, was not based upon structured portions of the questionnaires and was not systematically available for all registrants.

scholarly journals Role of serum sodium levels in recurrence and recurrent episodes of febrile seizure

2020 ◽  
Vol 7 (7) ◽  
pp. 1606
Author(s):  
Sara Benny
Keyword(s):  
Family History ◽  
Serum Sodium ◽  
Febrile Seizure ◽  
Febrile Seizures ◽  
Febrile Child ◽  
First Episode ◽  
Total Study Population ◽  
History Of ◽  
Low Serum

Background: Simple febrile seizures are the common childhood seizures, usually affecting 1 in 20 children between the age group of 6 months to 60 months. Earlier studies have shown an association between low serum sodium as a cause for febrile seizures and its recurrences. The present study was to determine the role of serum sodium in predicting febrile seizure recurrence within 24 hrs and recurrent episodes.Methods: Children aged between 6 months to 60 months with first episode of febrile seizures, admitted to the Paediatric ward of MOSC medical college Kolenchery, were recruited in the study. Inclusion criteria were demographic data, family history, clinical examinations, and laboratory investigations (serum sodium and hemoglobin).Results: Of the total study population of 100 children 33 had recurrences in 24 hours and 16 had recurrent episodes. About 57 children had a family history of febrile seizures, out which 28 children had recurrence of febrile seizure within 24 hours. 26 children had family history of epilepsy, of which only 8 had recurrences in 24 hours and 5 had recurrent episodes. Serum sodium levels of 69 children was above 130 mmol/l and 31 children had sodium level below 130mmol/l. Of 31 children, with low serum sodium levels (<130mmol/l), 29 had recurrence within 24 hours, which was not statistically significant. The sodium levels of 16 children who had recurrent episodes of seizure, was also between 130.1-135mmol/. No significant differences were seen between the serum sodium levels in simple febrile seizures and recurrent episodes.Conclusions: Study showed low serum sodium is not statistically significant to predict a recurrence within 24 hours, but a relative hyponatremia can predispose, a febrile child to occurrence of simple febrile seizure.

Ayurvedic understanding of Central Pontine Myelinolysis - A Case Report

2018 ◽  
Vol 3 (3) ◽  
Author(s):  
Anoop AS ◽  
Lakshmiprasad L. Jadhav ◽  
Sruthy Nair ◽  
Rohan Mohandas
Keyword(s):  
Serum Sodium Level ◽  
Central Pontine Myelinolysis ◽  
Chronic Alcoholism ◽  
Serum Electrolyte ◽  
Oral Medications ◽  
Shoulder Joints ◽  
Pontine Myelinolysis ◽  
Chief Complaints ◽  
Hyponatremic Encephalopathy ◽  
Central Pontine

A 56 year old male patient was admitted to S.D.M Ayurveda Hospital, Hassan, Karnataka with the confirmed diagnosis of Central Pontine Myelinolysis (CPM) on 11/12/17. The chief complaints were weakness of both hands and legs, stiffness in both hands and legs, pain in both shoulder joints, slurred speech, difficulty in walking with gait changes. H/O chronic alcoholism. MRI brain showed pontine and basal ganglia diffusion restriction - Acute Pontine Myelinolysis. The serum electrolyte showed serum sodium level as 128 mmol/litre. This disease can be understood as Samana Avruta Vyana in hyponatremic encephalopathy stage and the stage of myelinolysis can be understood as Sarvanga Vata with Kapha Avruta Udana and Vyana. After clinical evaluation, Avarana Chikitsa was started followed by Kevala Vatika Chikitsa and significant improvement was seen. Significant result was observed in subjective and objective parameters after the treatment. The patient was discharged with oral medications for 1 month.

Just Say No!

PEDIATRICS ◽  
1990 ◽  
Vol 86 (4) ◽  
pp. 624-624
Author(s):  
JOHN M. FREEMAN
Keyword(s):  
Febrile Seizure ◽  
Febrile Seizures ◽  
National Institutes Of Health ◽  
Consensus Development ◽  
Consensus Development Conference ◽  
Focal Seizures ◽  
The Family ◽  
History Of ◽  
Neurologic Development

A seizure, even a febrile seizure, is terrifying to the family. Seeking reassurance that their child will not die and does not have epilepsy, parents turn to their physician. What is he or she to do? Often the physician prescribes medication "to prevent further seizures" and then reassures the family that the child will be fine if the medicine is given daily as directed. Both the recommendation and the reassurance are wrong. A Consensus Development Conference on Febrile Seizures held by the National Institutes of Health in 19801 concluded that they would only "consider" anticonvulsant prophylaxis when the child (1) had abnormal neurologic development, (2) had long or focal seizures, (3) had more than two seizures in 24 hours, (4) had a history of nonfebrile seizures in parent or sibling, or (5) was younger than 1 years of age.

Abstract WP5: Outcomes Are Not Different Between Patients With Intermediate and High Dwi-aspects After Stent-retriever Thrombectomy

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Woong Yoon ◽  
Seul Kee Kim ◽  
Tae Wook Heo ◽  
Byung Hyun Baek ◽  
Jaechan Park
Keyword(s):  
Functional Outcome ◽  
Time Window ◽  
Multivariate Logistic Regression Analysis ◽  
Area Under The Curve ◽  
Stent Retriever ◽  
Operating Characteristics ◽  
Anterior Circulation ◽  
Good Outcome ◽  
Characteristics Analysis ◽  
The Impact

Introduction: Few studies have investigated the association between pretreatment DWI-ASPECTS and functional outcome after stent-retriever thrombectomy in patients with acute anterior circulation stroke. Hypothesis: Patients with acute stroke and DWI-ASPECTS <7 might have a similar chance of a good outcome compared to those with a higher DWI-ASPECTS, if they are treated with a stent-retriever thrombectomy in a short time window. However, this hypothesis has not been tested. Thus, this study aimed to investigate the impact of DWI-ASPECTS on functional outcome in patients with acute anterior circulation stroke who received a stent-retriever thrombectomy. Methods: We retrospectively analyzed the clinical and DWI data from 171 patients with acute anterior circulation stroke who were treated with stent-retriever thrombectomy within 6 hours of symptom onset. The DWI-ASPECTS was assessed by two readers. A good outcome was defined as a modified Rankin Scale score of 0-2 at 3 months. Results: The median DWI-ASPECTS was 7 (interquartile range, 6-8). Receiver operating characteristics analysis revealed an ASPECTS ≥ 7 was the optimal cut-off to predict a good outcome at 3 months (area under the curve=0.57; sensitivity, 75.3%; specificity, 34.4%). The rates of good outcome, symptomatic hemorrhage, and mortality were not different between high DWI-ASPECTS (scores of 7-10) and intermediate (scores of 4-6) groups. In patients with an intermediate DWI-ASPECTS, good outcome was achieved in 46.5% (20/43) of patients with successful revascularization (modified TICI 2b or 3), whereas no patients without successful revascularization had a good outcome ( P =0.016). In multivariate logistic regression analysis, independent predictors of good outcome were age and successful revascularization. Conclusions: Our study suggested that treatment outcomes were not different between patients with a high DWI-ASPECTS and those with an intermediate DWI-ASPECTS who underwent stent-retriever thrombectomy for acute anterior circulation stroke. Thus, patients with an intermediate DWI-ASPECTS otherwise eligible for endovascular therapy should not be excluded for stent-retriever thrombectomy or stroke trials.

GAMBARAN TINGKAT KECEMASAN ORANG TUA TERHADAP HOSPITALISASI ANAK DENGAN KEJANG DEMAM SELAMA ANAK DI RAWAT DI RUMAH SAKIT SANTA ELISABETH MEDAN TAHUN 2017

2017 ◽  
Vol 2 (2) ◽  
pp. 53-60
Author(s):  
Melky Rismando Damanik ◽  
Rusmauli Lumban Gaol
Keyword(s):  
Data Analysis ◽  
Febrile Seizure ◽  
Febrile Seizures ◽  
Anxiety Level ◽  
Parental Anxiety ◽  
Subjective Experiences ◽  
High Anxiety ◽  
Specific Object ◽  
Anxiety Levels ◽  
The Individual

Anxiety is an unclear and widespread concern, associated with feelings of uncertainty and helplessness. This state of anxiety and emotion has no specific object but can affect behavior toward parents whose children are hospitalized. Parental anxiety levels are subjective experiences of the individual and can not be directly observed but consequently will affect the anxiety level of the parent. Hospitalization of children is a state of crisis in children, when children are sick and hospitalized, one of them in the febrile seizure disease is a seizure spasm that occurs in the rise in body temperature above 38 ° C this will result in anxiety level of parents increases. Goals: To know the description of anxiety level of parent to hospitalization of child with febrile seizure during child is treated in hospital of Elisabeth Elisabeth Medan. Method: The design used in this study is descriptive to describe the level of anxiety parents to hospitalization of children with febrile seizures during child care at Hospital Santa Elisabeth Medan Year 2017. Result: based on data collection found 10 respondents where 5 (50%) of respondents who experienced anxiety level in medium category and 5 (50%) respondents have low level anxiety level. Conclusion: Based on the research and data analysis that has been done in accordance with the objectives that have been determined can be concluded that all parents who care for their children in the hospital will experience anxiety level that is 5 respondents (50%) with moderate anxiety level, while 5 others (50% Low anxiety levels and high anxiety levels were not found.

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