scholarly journals Serum Sodium Level on the Recurrence of Febrile Seizure within the Same Febrile Illness-Experience in a District Level Hospital

2019 ◽  
Vol 32 (1) ◽  
pp. 39-45
Author(s):  
M Luthfor Rahman ◽  
Belal Hossain ◽  
Belal Uddin ◽  
Sanaul Haq Mia
Keyword(s):  
Serum Sodium ◽  
Febrile Seizure ◽  
Sodium Level ◽  
Serum Sodium Level ◽  
Central Nervous System Infection ◽  
Febrile Illness ◽  
Febrile Seizures ◽  
Febrile Episode ◽  
Cross Sectional ◽  
Recurrent Seizure

Introduction: Febrile convulsion is the most common seizure disorder in the pediatric age group. It occurs in 2-5% of children. A febrile seizure is a seizure accompanied by fever (temperature 100.4°F or 38°C by any method), without central nervous system infection, that occurs in infants and children 6 through 60 months of age. Aim: The study was conducted to see the effect of serum sodium level on the recurrence of febrile seizure during the same febrile illness. Materials and Method: A cross-sectional descriptive study which enrolled 65 children admitted with febrile seizures at 100 bed district hospital, Naogaon. They were divided in to two groups, those with a single seizure and the rest were children with more than one seizures. Serum sodium levels were estimated after stabilization of patients. The probability of recurrent febrile seizures and serum sodium level was analyzed. Results: Hyponatremia (serum sodium <135 mmol/l) was seen in 12(18.5%) of 65 children and the remaining 81.5% children had normal serum sodium level (serum sodium 135-145 mmol/l). Among the hyponatremia group all children developed more than one seizure during the same febrile episode. The mean serum sodium level in patients with single and recurrent seizure was 138.48±2.17mmol/l and 135.27±3.11mmol/(P<0.001). The relationship between the probability of a recurrent seizure and serum sodium level is statistically highly significant. Conclusion: Estimation of the seum sodium in children with febrile seizures help in deciding for admission in hospital as well as to predict seizure recurrence within the same febrile episode. TAJ 2019; 32(1): 39-45

The Association between Serum Sodium Levels and Febrile Seizures Recurrence: Is the Degree of Hyponatremia a Risk Factor?

2021 ◽  
Author(s):  
Esma Keleş Alp ◽  
Ahmet Midhat Elmacı
Keyword(s):  
Serum Sodium ◽  
Medical Records ◽  
Febrile Seizure ◽  
Serum Sodium Level ◽  
Febrile Seizures ◽  
Lower Sensitivity ◽  
Operating Characteristics ◽  
Serum Electrolyte ◽  
Optimal Cutoff ◽  
Characteristics Analysis

AbstractFebrile seizures are common disorders in childhood. We evaluated the serum electrolyte levels and the associated factors in children with single and recurrent febrile seizures in 24 hours period of hospitalization. The medical records of children who were clinically diagnosed with febrile seizures and hospitalized were retrospectively revealed and analyzed. Data were collected for children aged 1 to 6 years including demographic parameters and serum electrolyte levels. A total of 244 children were enrolled in the study in which 209 were diagnosed with single febrile seizures and 35 of them with recurrent febrile seizures. Serum sodium levels were significantly lower in children with recurrent febrile seizure (138.5 ± 2.38 and 134.2 ± 3.55, p < 0.001). Correlation analysis revealed that mild hyponatremia is associated with recurrence of febrile seizure within 24 hours. However, receiver-operating characteristics analysis for hyponatremia showed lower sensitivity (50.3%) and specificity (43.1%) values for optimal cutoff value of 133.5 mmol/L of serum sodium level. Our study suggested that serum sodium levels were significantly lower in children with recurrent febrile seizures. However, because of its lower sensitivity and specificity values, mild hyponatremia cannot be used as an indicator for febrile seizure recurrence.

scholarly journals HUBUNGAN PENGETAHUAN, SIKAP DAN MOTIVASI IBU DENGAN PERILAKU PENCEGAHAN KEJANG DEMAM BERULANG PADA BALITA USIA 1- 5 TAHUN DI RSUD RADEN MATTAHER JAMBI

2018 ◽  
Vol 7 (2) ◽  
pp. 165
Author(s):  
Untung Tarunaji ◽  
Fithriyani Fithriyani
Keyword(s):  
Febrile Seizure ◽  
Quantitative Research ◽  
Central Nervous System Infection ◽  
Febrile Seizures ◽  
Seizure Type ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Prevention Behavior ◽  
Chi Square Test

ABSTRACTA febrile seizure is a seizure that occurs when an infant or child has a fever without central nervous system infection that occurs at temperatures over 380 C. a febrile seizure is seizure type most often encountered in childhood. This study aimed to determine the correlation of knowledge, attitude and mother’s motivation with behavior of febrile seizures prevention in toddlers’ age 1-5 years in the child’s room RSUD Raden Mattaher Jambi year 2017. This is a quantitative research by using cross sectional design, it used Accidental Sampling by using questionnaire instrument. This study analyzed as univariate and bivariate by using chi-square test with significant levels 95% (<0.05).The findings indicated that, 35 respondents as many as 19 (54.3%) have low knowledge, less good attitude as many as 20 (57.1%), less good motivation as many as 18 (51.4%) and less good prevention behavior 18 (51.4%). The result of chi-square test indicated that there is the correlation of knowledge, attitude and mother’s motivation with behavior of febrile seizures prevention in toddlers age 1-5 years in the child’s room RSUD Raden Mattaher Jambi year 2017 with p-value < 0.05 while the motivation, there is no correlation with behavior of febrile seizures prevention in toddlers age 1-5 years in the child’s room RSUD Raden Mattaher Jambi year 2017 p-value > 0.05. It is expected to RSUD Raden Mattaher Jambi is not only providing treatment but also providing health education periodically to increase of knowledge, attitude and mother’s motivation so the febrile seizures do not reoccur.

scholarly journals Serum Sodium Levels Predict the Recurrence of Febrile Seizure within 24 Hours

2019 ◽  
Author(s):  
Jatuporn Duangpetsang
Keyword(s):  
Family History ◽  
Serum Sodium ◽  
Medical Records ◽  
Febrile Seizure ◽  
Serum Sodium Level ◽  
Febrile Seizures ◽  
P Value ◽  
Seizure Recurrence ◽  
History Of

Objective: Febrile seizure is a common disorder in children that occurs in 2.5% of children 6-60 months of age. The study was conducted to ascertain the role of serum sodium as a predictor of seizure recurrence within the same febrile illness.Material and Methods: A retrospective study was conducted in children with febrile seizures who were admitted to Kaengkhro Hospital between 1 January 2014 and 31 December 2017. The data collected from medical records included age, gender, serum sodium level, body temperature, duration of fever, and family history of febrile seizures.Results: Two hundred ten children were diagnosed with febrile seizures; 190 had a single febrile seizure and 20 had recurrent febrile seizures. Mean±standard deviation ages of children with a single febrile seizure and recurrent febrile seizures were 22.95 ± 0.95 and 22.34 ± 0.89 months, respectively. Serum sodium levels in children with recurrent seizures within 24 hours (130.80 mmol/L) were significantly lower than in children with a single febrile seizure (132.37 mmol/L, p-value=0.02). A family history of febrile seizures was significant for predicting recurrent seizures within 24 hours (p−value= 0.006).Conclusion: Serum sodium levels predict the recurrence of febrile seizure within 24 hours.

Serum Sodium Level and Its Correlation with Curb-65 Score in Community Acquired Pneumonia – A Study from Bangalore, India

2021 ◽  
Vol 8 (30) ◽  
pp. 2702-2707
Author(s):  
Avinash Hanbe Rajanna ◽  
Swetha Rajoli ◽  
Nitish Ashok Gurav
Keyword(s):  
Serum Sodium ◽  
Sodium Level ◽  
Serum Sodium Level ◽  
Hormone Secretion ◽  
Community Acquired Pneumonia ◽  
Initial Assessment ◽  
Cross Sectional ◽  
Inappropriate Antidiuretic Hormone Secretion ◽  
High Sodium ◽  
Severity Scores

BACKGROUND Community acquired pneumonia (CAP) refers to pneumonia contracted by a person with little or no contact with health care system. Severity scores like CURB 65 severity score are useful in estimating the outcome. Hyponatremia is defined as serum sodium level < 135 mEq/L. The incidence of hyponatremia at hospital admission among CAP patients is found to be 28 %and the mechanism behind it has been found to be due to syndrome of inappropriate antidiuretic hormone secretion (SIADH). Hence this study is an effort to explore how hyponatremia is associated with severity and outcomes, in hospitalized patients with pneumonia. The purpose of this study was to assess the proportion of hyponatremia in patients with community acquired pneumonia and compare hyponatremia with CURB-65 as an initial screening tool for assessment of severity of CAP. METHODS This is a hospital-based cross-sectional study. 75 community acquired pneumonia patients admitted as inpatients are included in this study. Information is collected and detailed history is taken using pre-formed proforma at the time of admission. Serum sodium levels were measured, after initial assessment of patients. The lab values of serum sodium levels were analysed with the clinical profile and outcome in these study groups. RESULTS In our study, it was observed that as the sodium levels are decreasing, the CURB 65 score increases. Study subjects who had sodium levels < 125 mg/dl, presented with CURB 65 score as 4 (30 %). Inversely, the study subjects with high sodium levels (> 135 mg/dl) had CURB 65 scores as 1 (75 %). The association between sodium levels and CURB 65 score was significant in patients who got discharged but not in patients who expired. CONCLUSIONS Present study of serum sodium levels as biomarkers in CAP showed that hyponatremia carried poor prognosis which correlated with high CURB 65 score. KEYWORDS Sodium, Community Acquired Pneumonia, SIADH, CURB 65, Hyponatremia, COPD

scholarly journals Hyponatraemia in Community Acquired Bacterial and Tubercular Meningitis in Hospital Admitted Adult Patients

2014 ◽  
Vol 15 (2) ◽  
pp. 114-117
Author(s):  
Poly Sengupta ◽  
Md. Roushan Ali ◽  
Fazle Rabbi Mohammed ◽  
Rama Biswas ◽  
Mamunur Rashid ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Serum Sodium ◽  
Sodium Level ◽  
Serum Sodium Level ◽  
Clinical Importance ◽  
Tubercular Meningitis ◽  
Cross Sectional ◽  
Medical College ◽  
True Prevalence ◽  
Level Of Consciousness

Background: Bacterial and Tubercular Meningitis is a life-threatening disease. Hyponatraemia in bacterial and tubercular meningitis is a known complication with unknown true prevalence and clinical importance. This study was conducted to find out how commonly hyponatraemia occurs in community acquired bacterial and tubercular meningitis, to evaluate its severity, to see the pattern of presentation and to observe the level of consciousness. Materials and Methods: It was a descriptive cross sectional study performed in 30 admitted patients with clinically diagnosed bacterial and tubercular meningitis in medicine wards of Medical College for Women & Hospital (MCWH) and Dhaka Medical College & Hospital (DMCH) since August 2009 to March 2010. Serum electrolyte and level of consciousness on admission was recorded in all patients. Results: Twenty Nine patients (96.7%) with meningitis had hyponatraemia, serum sodium level ranged from 115-138 mmol/l; mean sodium level is 128.57 ± 5.56 SD mmol/L. Serum sodium level was mild (>125-135 mmol/L) in 20 (66.7%) patients with meningitis and moderate (110-125 mmol/L) in 9 (30%) and severe (<110 mmol/L) in 1 (3.3%) patient. GCS ranged from 8 to 14, mean 11.56±1.40 SD in day 1. In tubercular meningitis (n=8) and bacterial meningitis (n=22) serum sodium level was 128.63±7.44 and 128.55±4.93 while mean GCS was 11.38±2.13 and 11.95±1.40 respectively on the day of admission. Conclusion: Although the true prevalence, severity and clinical importance of hyponatraemia in bacterial meningitis are unknown, its presence may influence the outcome in such patients depending on severity. So knowledge about its prevalence and severity will guide physicians to take decisions about its management.DOI: http://dx.doi.org/10.3329/jom.v15i2.20682 J MEDICINE 2014; 15 : 114-117

scholarly journals Asymptomatic hypernatremia in exclusively breastfed neonates

2019 ◽  
Vol 6 (4) ◽  
pp. 1642
Author(s):  
Babalala Kadegaon ◽  
Jyoti B. Sarvi
Keyword(s):  
Serum Sodium ◽  
Odds Ratio ◽  
Sodium Level ◽  
Adjusted Odds Ratio ◽  
Significant Positive Correlation ◽  
Serum Sodium Level ◽  
Mode Of Delivery ◽  
Summer Season ◽  
Cross Sectional ◽  
Positive Correlation

Background: The aim of study was to identify the asymptomatic hyparnatremia in exclusively breastfed neonates and to study the factors associated with it.Methods: A cross-sectional study was conducted from November 2010 to October 2012 in Jawaharlal Nehru Medical College and Hospital, A. M. U., Aligarh. Consecutive term appropriate-for-gestational age and asymptomatic neonates who were exclusively breastfed since birth were enrolled.Results: A total of 1360 term neonates were screened, out of which 145 neonates in each early and late neonatal group were enrolled. Prevalence of hypernatremia in 290 patients was 4.48% (n=13) with mean serum sodium level of 156.6±5.5 mmol/L, ranging from 151 to 167 mmol/L. It was 16 times more common in early compare to late neonates (adjusted odds ratio=16.074, P=0.001), 6 times more common in primi mothers (adjusted odds ratio=6.037, P=0.010) and 7 times more common during summer season (May-August) (adjusted odds ratio=6.566, P=0.017). Other variables like sex, mode of delivery and blood urea levels do not show significant association with hypernatremia. There was a significant positive correlation of serum sodium level with blood urea (r=0.123, P=0.037) and serum creatinine levels (r=0.157, P=0.007), and a negative correlation with blood sugar levels, but it was not significant (r=-0.072, P=0.224).Conclusions: The prevalence of hypernatremia in exclusively breastfed term asymptomatic neonates is 4.8%, and is more common in early neonatal period, in summer season and in babies born to primi mothers. There was a significant positive correlation of serum sodium with blood urea and creatinine levels.

scholarly journals The association between serum sodium level and tuberculous meningitis compared with viral and bacterial meningitis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seunghee Na ◽  
Taewon Kim ◽  
In-Uk Song ◽  
Sung-Woo Chung ◽  
Seong-Hoon Kim ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Bacterial Meningitis ◽  
Tuberculous Meningitis ◽  
Serum Sodium ◽  
Sodium Level ◽  
Total Population ◽  
Serum Sodium Level ◽  
Viral Meningitis ◽  
Cross Sectional ◽  
Additional Information

AbstractWe evaluated the association between hyponatremia and tuberculous meningitis (TBM) with the aim of providing additional information for differential diagnosis from other types of infectious meningitis, especially viral meningitis (VM). Cross-sectional and longitudinal data involving 5026 participants older than 18 years were analyzed in the total population and a propensity-matched population. The initial and lowest sodium levels and longitudinal changes in TBM, bacterial meningitis (BM), and VM patients were compared. Participants in the TBM group were enrolled when they were diagnosed as possible, probable, or definite TBM according to the Marais’ criteria. The initial serum sodium level was significantly lower in TBM patients than in BM and VM patients (136.9 ± 5.9 vs. 138.3 ± 4.7 mmol/L, p < 0.001 for TBM vs. BM, and 139.0 ± 3.1, p < 0.001 for TBM vs. VM), and it decreased significantly more steeply to lower levels in both the TBM and BM patients compared with VM patients. The lowest serum sodium level was in the order of TBM < BM < VM patients, and the change was statistically significant in all subgroups (131.8 ± 6.4, 133.1 ± 5.1, 137.4 ± 3.7, respectively, p < 0.001). Participants with lower serum sodium level were more likely to have a diagnosis of TBM rather than VM, and this association was more pronounced for the lowest sodium level than the initial sodium level [OR 4.6 (95% CI 2.4–8.8, p < 0.001)]. These findings indicate that baseline and longitudinal evaluation of serum sodium level can provide information for differential diagnosis of TBM from BM or VM.

scholarly journals Treatment of febrile seizures with intermittent clobazam

1997 ◽  
Vol 55 (4) ◽  
pp. 757-761 ◽  
Author(s):  
Maria Luiza G. Manreza ◽  
José Luiz D. Gherpelli ◽  
Lúcia R. Machado-Haertel ◽  
Cristiane C. Costas Pedreira ◽  
Carlos O. Heise ◽  
...  
Keyword(s):  
Central Nervous System Infection ◽  
Drug Efficacy ◽  
Febrile Seizures ◽  
Febrile Episode ◽  
Intermittent Therapy ◽  
Simple Type ◽  
Recurrent Vomiting ◽  
Symptomatic Seizures ◽  
Febrile Episodes ◽  
A Prospective Study

Fifty children, 24 female and 26 male, with ages varying from 6 to 72 months (mean=23.7 m.) that experienced at least one febrile seizure (FS) entered a prospective study of intermittent therapy with clobazam. Cases with severe neurological abnormalities, progressive neurological disease, afebrile seizures, symptomatic seizures of other nature, or seizures during a central nervous system infection were excluded. Seizures were of the simple type in 25 patients, complex in 20 and unclassified in 5. The mean follow-up period was 7.9 months (range=l to 23 m.), and the age at the first seizure varied from 5 to 42 months (mean=16.8 m.). Clobazam was administered orally during the febrile episode according to the child's weight: up to 5 kg, 5 mg/day; from 5 to 10 kg, 10 mg/day; from 11 to 15 kg, 15 mg/day, and over 15 kg, 20 mg/day. There were 219 febrile episodes, with temperature above 37.8 °C, in 40 children during the study period. Twelve children never received clobazam and 28 received the drug at least once. Drug efficacy was measured by comparing FS recurrence in the febrile episodes that were treated with clobazam with those in which only antipyretic measures were taken. Ten children (20%) experienced a FS during the study period. Of the 171 febrile episodes treated with clobazam there were only 3 recurrences (1.7%), while of the 48 episodes treated only with antipyretic measures there were 11 recurrences (22.9%), a difference highly significant (p<0.0001). Adverse effects occurred in 10/28 patients (35.7%), consisting mainly in vomiting, somnolence and hyperactivity. Only one patient had recurrent vomiting which lead to drug interruption. These effects did not necessarily occurred in every instance the drug was administered, being present in one febrile episode and not in the others. We conclude that clonazepam is safe and efficacious in preventing FS recurrence. It may be an alternative to diazepam in the intermittent treatment of FS recurrence.

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