Outcomes of Total Knee Arthroplasty in Patients with Prior Hardware: A Case–Control Study Using Handheld Navigation

2021 ◽  
Author(s):  
Rajesh Malhotra ◽  
Aditya Jain ◽  
Saurabh Gupta ◽  
Deepak Gautam
Keyword(s):  
Operative Time ◽  
Case Control Study ◽  
Case Control ◽  
Group A ◽  
Total Knee ◽  
Post Traumatic ◽  
Group B ◽  
Removal Of Hardware ◽  
Traumatic Arthritis ◽  
Control Study

AbstractPresence of hardware in juxta-articular location poses challenge during total knee arthroplasty (TKA). When present in distal femur, it precludes the use of an intramedullary femoral jig during TKA often necessitating removal of hardware leading to prolonged surgery, higher risk of complications, and inferior results. We conducted a case–control study to assess the outcome of TKA among patients with post-traumatic arthritis using a handheld navigation system to perform bone cuts allowing retention of hardware in situ. In 15 patients with post-traumatic arthritis and hardware around the knee (Group A), none or part(s) of hardware were removed while performing TKA. These patients were matched to 15 patients who underwent TKA with handheld navigation for primary OA knee (Group B). The perioperative outcomes assessed were operative time, intraoperative blood loss, length of hospital stay, complications, and 30 days reoperation rate. Clinical outcomes were assessed by using Knee Society Score (KSS) and radiological outcomes using mechanical axis and coronal and sagittal component angles. Mean age of patients at surgery were 65.67 years (Group A) and 66.73 years (Group B). Mean operative time and blood loss were significantly higher in Group A as compared with Group B. At the mean follow-up of 34 months, KSS significantly improved in both the groups. However, there was no statistically significant difference in the clinical and radiological outcomes between the two groups. One patient in Group A developed wound dehiscence and had to undergo debridement and flap coverage within 30 days. The use of navigation helps surgeons in gaining proper limb alignment and implant positioning without complete removal of hardware.

scholarly journals Isoflavone in Postmenopausal Women - Are They Really Effective? A Prospective Case Control Study.

2013 ◽  
Vol 7 (1) ◽  
pp. 11-14 ◽  
Author(s):  
TS Bag ◽  
Amit Kyal ◽  
DP Saha ◽  
R Dutta ◽  
S Mondal
Keyword(s):  
Blood Pressure ◽  
Postmenopausal Women ◽  
Case Control Study ◽  
Case Control ◽  
Menopausal Symptoms ◽  
Kupperman Index ◽  
Group A ◽  
Group B ◽  
Control Study ◽  
Prospective Case Control Study

A prospective case control study was conducted at Medical College, Kolkata with the aim of evaluating the role of isoflavone( a class of phytoestrogen –plant compounds having the beneficial effects of estrogen but lesser risks and side effects) in postmenopausal women. 100 postmenopausal women (those who underwent total abdominal hysterectomy and bilateral salpingooopherectomy for different benign indications, aged between 40-50 years and who were menstruating before operation) were alternately distributed into two groups-Group A (n=50, received 60mg of isoflavone and 500mg of calcium per day for 6 months) and Group B (n=50, received 500mg of calcium per day only for 6 months). To evaluate the menopausal symptoms, the menopausal Kupperman index questionnaire was applied. Other outcomes measured were body mass index, blood pressure and lipid profile. Menopausal symptoms in Group A(those using isoflavones) were lower compared to Group B. The present study showed that Kupperman index decreased significantly in Group A (from 28.48 ± 2.03 to 16.32 ± 1.06 i.e. 45% decline) compared to Group B (from 24.56 ± 1.52 to 18.44 ± 1.11 i.e. 25% decline). No differences in blood pressure or body mass index were found during treatment between the two groups. . In our study total cholesterol, triglycerides and low-density lipoproteins (LDL) decreased significantly in Group A compared to Group B. Therefore our clinical study indicates that isoflavone can be an invaluable resource for postmenopausal women for combating menopausal symptoms. Nepal Journal of Obstetrics and Gynaecology / Vol 7 / No. 1 / Issue 13 / Jan- June, 2012 / 11-14 DOI: http://dx.doi.org/10.3126/njog.v7i1.8826

Clinical Factors in Trunk Capillary Malformations in the Neonate: When to Suspect Other Associated Malformations? A Case–Control Study

2019 ◽  
Vol 30 (01) ◽  
pp. 122-126
Author(s):  
Carlos Delgado-Miguel ◽  
Miriam Vicente ◽  
Antonio Jesus Serrano-Muñoz ◽  
Miriam Miguel-Ferrero ◽  
Mercedes Diaz ◽  
...  
Keyword(s):  
Case Control Study ◽  
Vascular Malformations ◽  
Venous Malformation ◽  
Clinical History ◽  
Case Control ◽  
Gender And Age ◽  
Group A ◽  
Associated Malformations ◽  
Group B ◽  
Control Study

Abstract Introduction Capillary malformations (CMs) can be sporadic or syndromic, in association with other underlying venous malformation (VM) or lymphatic malformation (LM). The objective of this study is to describe the clinical patterns in the neonate that allow us to differentiate sporadic CMs from those associated with other vascular malformations. Materials and Methods A case–control study was performed in neonates with CM located in the trunk, followed at our institution between 2008 and 2018. The patients were divided into two groups: group A (cases: CM associated with VM or LM) and group B (controls: sporadic CM without associated malformations). Demographic and clinical variables collected in the clinical history were evaluated (color, location, multifocality, bilaterality, position regarding the vascular axis, and involvement of the midline). Results Thirty-eight patients were included (18 cases and 20 controls) without differences in gender and age. In group A, the totality of patients presented CM with uniform color and lateral location (p < 0.001). In this group, bilateral and multifocal involvements were lower than in group B, without significant differences between both groups. The distribution of CMs in group A was always parallel to the vascular axis and the midline was always respected, without observing these characteristics in the group B (p < 0.001). Conclusion The presence of a CM in the trunk of a neonate with uniform color, lateral location, parallel position to the vascular axis, and absence of involvement of the midline should make us suspect other underlying vascular malformations, which should be studied with complementary tests.

scholarly journals Minimally invasive total knee arthroplasty using the contralateral knee as a control group: a case-control study

2009 ◽  
Vol 34 (4) ◽  
pp. 491-495 ◽  
Author(s):  
Peter M. Bonutti ◽  
Michael G. Zywiel ◽  
Thorsten M. Seyler ◽  
Seung Yong Lee ◽  
Mike S. McGrath ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Minimally Invasive ◽  
Knee Arthroplasty ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Contralateral Knee ◽  
Group A ◽  
Total Knee ◽  
Control Study

scholarly journals Nonsurgical Periodontal Therapy decreases the Severity of Rheumatoid Arthritis: A Case–control Study

2016 ◽  
Vol 17 (6) ◽  
pp. 484-488 ◽  
Author(s):  
Neha Khare ◽  
Bhavuk Vanza ◽  
Deepak Sagar ◽  
Kumar Saurav ◽  
Rohit Chauhan ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Oral Hygiene ◽  
Case Control Study ◽  
Case Control ◽  
Periodontal Therapy ◽  
Clinical Observations ◽  
Nonsurgical Periodontal Therapy ◽  
Group A ◽  
Group B ◽  
Control Study

ABSTRACT Introduction Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory conditions. Several studies suggested a relationship between RA and periodontitis. Recent studies have shown a beneficial effect of periodontal treatment on the severity of active RA. So the aim of this study was to examine the effect of nonsurgical periodontal therapy on the clinical parameters of RA. Materials and methods A total of 60 subjects with moderateto- severe chronic generalized periodontitis and active RA in the age range 18 to 65 were selected for the study. They were divided into two groups. Group A (control group) consisted of 30 subjects with chronic generalized periodontitis and RA, and group B of 30 subjects with chronic generalized periodontitis and RA and they received nonsurgical periodontal therapy (scaling, root planning, and oral hygiene instructions). Evaluation of clinical observations of Simplified Oral Hygiene Index (OHI-S), gingival index (GI), bleeding on probing (BOP), probing pocket depth (PPD), clinical attachment level (CAL), number of swollen joints (SJ), number of tender joints (TJ), values of erythrocyte sedimentation rate (ESR), visual analogue scale (VAS) for patient's global assessment, 3 months disease activity score (DAS) index, and C-reactive protein (CRP) was done at baseline and 3 months. Statistical evaluation of clinical observations was carried out. Results Group B subjects who received nonsurgical periodontal therapy showed statistically significant improvement in all periodontal and RA parameters at 3 months, compared with group A who did not receive periodontal therapy. Conclusion It can be concluded from the result that nonsurgical periodontal therapy may contribute to reduction in severity and symptoms of RA. Clinical significance Rheumatoid arthritis patients should be evaluated for periodontitis and treated for the same in order to reduce its severity level. How to cite this article Khare N, Vanza B, Sagar D, Saurav K, Chauhan R, Mishra S. Nonsurgical Periodontal Therapy decreases the Severity of Rheumatoid Arthritis: A Case–control Study. J Contemp Dent Pract 2016;17(6):484-488.

A Preliminary Case-Control Study: Peritoneal Approach in Congestive Heart Failure Treatment

2021 ◽  
pp. 1-7
Author(s):  
Paolo Ria ◽  
Gianluca Borio ◽  
Carlo Rugiu ◽  
Isabella Corino ◽  
Luisa Zanolla ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Major Event ◽  
Event Free Survival ◽  
Free Survival ◽  
Group A ◽  
Number Of Visits ◽  
Group B ◽  
Control Study

<b><i>Background:</i></b> Congestive heart failure (CHF) associated with worsening renal function is a very common disorder, and, as well known, the goal of the treatment is reducing venous congestion and maintaining a targeted extracellular volume. The objective of the study is to evaluate regular peritoneal ultrafiltration treatment compared to a standard conservative approach in NYHA III–IV CHF patients. In particular, the primary endpoints of the study were the major event-free survival and the total days of medical care per month (which consist of the days of hospitalization and the number of outpatient visits). <b><i>Material and Methods:</i></b> This is a retrospective case-control study. Twenty-four patients were included in the present study. Twelve consecutive patients were treated with peritoneal treatment (group A) and 12 matched for age, gender, and severity of disease with a standard approach. Patients were observed over a maximum period of 18 months. Information on events, hospitalizations, and number of visits was collected during follow-up. <b><i>Results:</i></b> During the follow-up, we observed a major event in 4 patients in group A (33.3%) and in 8 patients in group B (66.7%). In group B, we observed 7 deaths and 1 ICD shock, while in group A, 3 deaths and 1 ICD shock. The number of visits per month was significantly lower in patients treated with the peritoneal method (1.2 [0.4–4.1] vs. 2.5 [2.0–3.1]; <i>p</i> = 0.03). The total days of medical care was significantly lower in group A (2.0 [1.1–5.5] vs. 4.4 [3.0–8.7]; <i>p</i> = 0.034). A multiple event analysis according to the Andersen-Gill model showed a significant event-free survival for group A. During the follow-up, we did not observe any episode of peritonitis in the treated group. <b><i>Conclusions:</i></b> Our study shows that the peritoneal technique is a good therapeutic tool in well-selected patients with CHF. In accordance with prior experience, this intervention has not only an important and significant clinical impact but also potential economic and social consequences.

scholarly journals Testicular shear wave elastography in oligo-astheno-teratozoospermic individuals: a prospective case–control study

2021 ◽  
Author(s):  
Ester Illiano ◽  
Francesco Trama ◽  
Antonio Ruffo ◽  
Giuseppe Romeo ◽  
Filippo Riccardo ◽  
...  
Keyword(s):  
Shear Wave ◽  
Case Control Study ◽  
Shear Wave Elastography ◽  
Case Control ◽  
Semen Parameters ◽  
Control Group ◽  
Group A ◽  
Group B ◽  
Control Study ◽  
Prospective Case Control Study

Abstract Purpose The primary objective of this study was to evaluate the testicular stiffness by ultrasound shear wave elastography (SWE) both in men with oligo-astheno-teratozospermia (OAT) and in control group. The secondary objective was to identify a possible correlation between semen quality with testicular stiffness. Methods This was a prospective case-control study. We divided the sample in two groups; Group A (case group) included men with OAT, and Group B (control group) men with normal sperm parameters. All participants had at last two semen analysis in the past 180 days (at last 90 days apart), using performed ultrasound and SWE elastography. Results We analyzed 100 participants, 50 patients in Group A and 50 controls in Group B. There were statistically significant differences in term of testicular volume and testicular stiffness between two groups. Men with OAT had the testicular stiffness value higher than the controls in both sides (left testicular stiffness 21.4 ± 5.4 kPa vs 9.9 ± 1.6 kPa, p < 0.0001; right testicular stiffness 22.9 ± 4.8 kPa vs 9.5 ± 2.4 kPa, p < 0.0001). Men with abnormal semen parameters showed an inverse correlation between the mean value of testicular stiffness and total sperm count (22.15 ± 3.38 kPa, r = − 0.387, p = 0.005), sperm concentration (22.15 ± 3.38 kPa, r = − 0.244, p = 0.04), and progressive motility (22.15 ± 3.38 kPa, r = − 0.336, p = 0.01), while the correlation was not evident in controls group. Conclusion SWE is able to differentiate between testicles with spermatogenic changes from a healthy testicle. For this reason, it could be used to evaluate, in a non-invasive way, the tissue alterations of the organ.

scholarly journals Is Wide-Awake Local Anesthesia No Tourniquet Technique in Distal Radius Plating Surgery a Comfortable Procedure? A Prospective Case-Control Study

2020 ◽  
Author(s):  
Chun-Kuan Lu ◽  
Wen-Chih Liu ◽  
I-Chen Lu ◽  
Chung-Chia Chang ◽  
Chia-Lung Shih ◽  
...  
Keyword(s):  
Distal Radius ◽  
Case Control Study ◽  
Case Control ◽  
Group A ◽  
Intraoperative Pain ◽  
Group B ◽  
Wide Awake ◽  
No Tourniquet ◽  
Control Study ◽  
Prospective Case Control Study

Abstract Background: Wide-awake local anesthesia no tourniquet (WALANT) is a promising technique for bony procedure in recent years. During distal radius surgery via WALANT technique, surgeons may concern about intraoperative pain. This prospective case-control study was aimed to compare the intraoperative hemodynamic changes between WALANT technique and general anesthesia (GA) in patients undergoing distal radius plating surgery.Methods: We recruited 40 adults with distal radius fracture underwent plating using the WALANT technique (group A) or general anesthesia (group B). Each group comprised 20 patients with similar demographics. Mean arterial pressure (MAP) and heart rate were recorded in both groups. Intraoperative pain intensity was measured by numeric rating scale (NRS) for pain in group A.Results: The NRS decreased significantly compared with preoperative status in group A for most of the intraoperative period. The intraoperative MAP in group A showed no significant change among each peri-operatively period. In addition, group A showed less peri-operative MAP fluctuation than group B (p< 0.05). The intraoperative changes in HR showed significant changes between group A and B during reduction, plating and skin closure. The reduction and plating quality were similar between each group.Conclusions: Patients undergoing distal radius plating surgery via WALANT technique has a lower MAP changes. Distal radius plating surgery using the WALANT technique is a well-tolerated surgical procedure and showing the similar reduction and plating quality to through GA.

Comparison of Various Progesterone Drugs in Reducing Miscarriages

2021 ◽  
Vol 15 (5) ◽  
pp. 971-973
Author(s):  
Hina Zubair ◽  
Lubna Riaz ◽  
Fartash Zahra ◽  
Sara Saeed Malik ◽  
Rabail Javed
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Common Complication ◽  
Medical College ◽  
Drug Of Choice ◽  
Vaginal Administration ◽  
Group A ◽  
Threatened Abortion ◽  
Group B ◽  
Control Study

Background: Threatened abortion is a common complication of pregnancy. In order to prevent miscarriage progesterone in various forms is administered in patients. This is done to allow pregnancy to proceed further beyond twenty week of gestation. Aim: To compare gravibinan (injected) with utrogestan/cyclogest (intra vaginal administration) in reduction of miscarriages. Study design: Case control study Place and duration of study: Department of Obstetrics & Gynecologiy, Mohtrama Benzair Bhutto Shaheed Medical College Mirpur and Department of Pediatric, Shaikh Zayed Hospital Lahore from 1st April 2020 to 30th September 2020. Methodology: Pregnant women, who had vaginal bleeding until 20 weeks of their pregnancy, were assessed for inclusion. Participants were divided into three groups. Group A was given gravibinan, Group B was given utrogestan and Group C was given cyclogest. Results: Women infested with gravibinan had 20% those who still had miscarriage while the number of miscarriages significantly decreased to 14.2% in utrogestan group and 13.63% in cyclogest group (p<0.005). Conclusion: Cyclogest proved a better drug of choice for reducing miscarriages. Keywords: Miscarriages, progesterone, pregnancy

scholarly journals Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study

2020 ◽  
Vol 9 (5) ◽  
pp. 1264 ◽  
Author(s):  
Piero Papi ◽  
Andrea Raco ◽  
Nicola Pranno ◽  
Bianca Di Murro ◽  
Pier Carmine Passarelli ◽  
...  
Keyword(s):  
Dental Implants ◽  
Inductively Coupled Plasma ◽  
Case Control Study ◽  
Case Control ◽  
Repeated Measure ◽  
Control Group ◽  
Metallic Ions ◽  
Group A ◽  
Group B ◽  
Control Study

Background: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni) and arsenic (As) ions among patients with dental implants, healthy (Group A) or affected by peri-implantitis (Group B), compared to subjects without implants and/or metallic prosthetic restorations (Group C). Methods: Inductively coupled plasma mass spectrometry was used to analyze saliva samples. One-way repeated-measure analysis of variance (ANOVA) was used to identify statistically significant differences in the salivary level of Ti, V, Ni and As between the three groups. Results: A total of 100 patients were enrolled in the study (42 males and 58 females), distributed in three groups: 50 patients in Group C, 26 patients in Group B and 24 patients Group B. In our study, concentrations of metallic ions were higher in Group A and B, compared to the control group, with the exception of vanadium. However, there were no statistically significant differences (p > 0.05) for metallic ions concentrations between Group A and Group B. Conclusions: Based on our results, there are no differences in titanium or other metals concentrations in saliva of patients with healthy or diseased implants.

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