Severe Irreversible Optic Neuritis Following Mantoux Tuberculin Skin Test in a Child with Multiple Sclerosis - A Case Report

1997 ◽  
Vol 28 (06) ◽  
pp. 338-340
Author(s):  
W. Linssen ◽  
J. Kruisdijk ◽  
F. Barkhof ◽  
L. Smit
2008 ◽  
Vol 93 (2) ◽  
pp. 263-267 ◽  
Author(s):  
Thomas B. Daniels ◽  
Bruce E. Pollock ◽  
Robert C. Miller ◽  
Claudia F. Lucchinetti ◽  
Jacqueline A. Leavitt ◽  
...  

PEDIATRICS ◽  
1976 ◽  
Vol 58 (2) ◽  
pp. 291-291
Author(s):  
Dana M. Brasfield ◽  
Travis B. Goodloe ◽  
Ralph E. Tiller

A case of isoniazid-associated hepatitis has been encountered in a pediatric patient. Only two previous such patients have been reported in the pediatric literature.1,2 Both of those children had more cutaneous manifestations than liver involvement. For this reason the following patient is presented. CASE REPORT V.R. is a black girl who was admitted to The Children's Hospital at 12 years of age for evaluation of pericarditis. The tuberculin skin test (PPD-5 T.U.) was positive with 20 mm of induration. Further studies, including cultures of pericardial fluid, eventually failed to prove a tuberculous etiology for the pericarditis. However, antituberculous therapy for at least one year was considered desirable.


2020 ◽  
Vol 2 (5) ◽  
pp. 1-4
Author(s):  
Vajed Mogal ◽  
◽  
Mahendra Wawhal ◽  

Multiple sclerosis is a neurological disease, which affects young adults. Its course is unpredictable and runs over decades. It is considered as disease of unknown etiology in which there is demyelination of the brain and spinal cord. There is one case report of membranous GN in a case of progressive multiple sclerosis in the extant world literature. We report here perhaps the first case in the world of the occurrence of multiple sclerosis in a known case of chronic kidney disease with the presentation of acute optic neuritis, having a characteristics picture on MRI of multiple sclerosis in brain, abnormal VEP, oligoclonal bands in CSF and a prior episode of acute optic neuritis 3 years back. In our opinion, this case opens the flood gates for research & work to investigate whether the oxidative stress and the smouldering proinflammatory state in CKD can precipitate multiple sclerosis in a genetically predisposed host in a given environment. Multiple Sclerosis is often associated with a neurogenic bladder, but renal function is generally considered to be normal.


2020 ◽  
Vol 6 (2) ◽  
pp. 74-77
Author(s):  
Mohammad Enayet Hussain ◽  
Bithi Debnath ◽  
AFM Al Masum Khan ◽  
Md Ferdous Mian ◽  
Md Nahidul Islam ◽  
...  

Background: The visual evoked potentials (VEP) is a valuable tool to document occult lesions of the central visual channels especially within the optic nerve. Objectives: The purpose of the present study was to observe the findings of first few cases of VEP done in the neurophysiology department of the National Institute of Neurosciences (NINS), Dhaka, Bangladesh. Methodology: This cross-sectional study was conducted in the Department of Neurophysiology at the National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2017 to March 2020. All patients referred to the Neurophysiology Department of NINS for VEP were included. Pattern reversal VEPs were done using standard protocol set by International Federation of Clinical Neurophysiology (IFCN). Results: The mean age of the study population was 30.70 (±12.11) years (6-68 years) with 31 (46.3%) male and 36 (53.7%) female patients. The mean duration of illness was 8.71 (±1.78) months (3 days- 120 months). Most common presenting symptom was blurring of vision (37.3%) and dimness of vision (32.8%). Patterned VEP revealed mixed type (both demyelinating and axonal) of abnormality in most cases [29(43.35)]. The most common clinical diagnosis was multiple sclerosis (29.85%) and optic neuropathy (26.87%). In the clinically suspected cases of multiple sclerosis, optic neuropathy and optic neuritis most of the cases of VEP were abnormal and the p value is 0.04 in optic neuropathy and optic neuritis. Conclusion: The commonest presentation of the patients in this series were blurring of vision and dimness of vision. The most common clinical diagnosis for which VEP was asked for, was optic neuritis and multiple sclerosis. Most abnormalities were of mixed pattern (demyelinating and axonal). Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 74-77


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