Role of the Perinatal Autopsy in Evaluating Unusual Sonographic Findings of Intrauterine Fetal Death

1989 ◽  
Vol 6 (03) ◽  
pp. 331-333 ◽  
Author(s):  
Lyndon Hill ◽  
Trevor Macpherson ◽  
Hanae Belfar ◽  
Sandra Kislak
2021 ◽  
Vol 12 ◽  
Author(s):  
Yue Zu ◽  
Jinyu Yang ◽  
Chengliang Zhang ◽  
Dong Liu

Estrogens are steroid hormones with a wide range of biological activities. The excess of estrogens can lead to decreased bile flow, toxic bile acid (BA) accumulation, subsequently causing intrahepatic cholestasis. Estrogen-induced cholestasis (EIC) may have increased incidence during pregnancy, and within women taking oral contraception and postmenopausal hormone replacement therapy, and result in liver injury, preterm birth, meconium-stained amniotic fluid, and intrauterine fetal death in pregnant women. The main pathogenic mechanisms of EIC may include deregulation of BA synthetic or metabolic enzymes, and BA transporters. In addition, impaired cell membrane fluidity, inflammatory responses and change of hepatocyte tight junctions are also involved in the pathogenesis of EIC. In this article, we review the role of estrogens in intrahepatic cholestasis, and outlined the mechanisms of EIC, providing a greater understanding of this disease.


Author(s):  
Kajal Patra ◽  
Shibram Chattopadhyay ◽  
Poulami Samanta ◽  
Chandrakanta Mondal

Background: Intrauterine fetal death(IUFD) is an unhappy reality, a lamentable incidence for both the family and the caregiver. It is an important indicator of both maternal and perinatal health in a population. The study of fetal death is crucial in promoting actions for maternal and child health. Aim of this study was to determine the incidence, indications and maternal morbidity and maternal mortality associated with caesarean section in patients with IUFD and to establish the place of caesarean section in present day scenario.Methods: The study was a retrospective analysis of all caesarean section carried out in a case of IUFD in last 5 years (2013-2017). The indications, incidence, maternal morbidity, mortality was studied well in this time period in a rural medical college of West Bengal.Results: Total 108425 deliveries occurred in the hospital in last 5 years, out of which 31800 were caesarean section. 56 cases were done in case of diagnosed IUFD. There was 2489 number of IUFDs in the given period. The incidence of IUFD was 22.96 per 1000 deliveries. Induction was done in 2489 cases; 56 cases underwent caesarean section (2.25%) and rest was delivered vaginally.Conclusions: Early diagnosis, early referral and proper antenatal checkup can reduce the chances of IUFD and number of caesarean deliveries in IUFD. The role of cesarean deliveries in previous caesarean deliveries having IUFDs has been emphasized.


2018 ◽  
Vol 9 (4) ◽  
pp. 113-117
Author(s):  
Zlata V. Davydova ◽  
Olga V. Sokolova

The analysis of expert practice and scientific research conducted during the last decade show that the greatest number of claims to the correctness of the provision of medical care are made by doctors of surgical specialties, including obstetrician-gynecologists, and, at the same time, inspections for “medical cases”, including profile “obstetrics and gynecology” are complex and time-consuming. The article considers the problem of the unfavorable outcome of medical care in obstetric practice. The questions of etiology, pathogenesis, diagnosis of intrauterine infection (VUI), which largely determines the frequency of perinatal morbidity and mortality, are also analyzed and analyzed questions of the prescription of the pathological process in the amniotic membranes, its role in the formation of fetal death. On a concrete example, expert practice shows how the forensic medical commission, taking into account the data of medical documents, as well as the results of macroscopic and microscopic studies, solves the problem of the immediate cause of antenatal death and establishes the role of intrauterine infection in the death of the fetus, the timing and causes of its formation. The information that is relevant to the practice of forensic medical examinations is presented, which allows us to formulate objective and scientifically substantiated conclusions about the existence of cause-effect relationships between the defects in the provision of medical care and the onset of an unfavorable outcome of medical care in similar cases.


2014 ◽  
Vol 32 (1) ◽  
pp. 16-20
Author(s):  
SF Nargis ◽  
R Ara ◽  
G Ara ◽  
Jahanara Begum

Objective: To study the role of internal podalic version (IVP) in the management of transverse lie with fetal demise in labour and to assess the success and outcome of this almost obsolete procedure in obstetrics. Materials and Methods: Quasi experimental study was done in Shaheed Ziaur Rahman Medical College and Mohammad Ali Hospital, Bogra from January 2001 to December 2006. Results: Within this period total 180 cases transverse lie with intrauterine fetal death (IUFD) were studed. All these case were undiagnosed transverse lie with IUFD in labour and admitted in the hospital through the emergency department. In 60 cases IPV and in 120 cases lower uterine segment caesarean section (LUCS) were done to deliver the dead for per operative and post operative blood transfusion were only 03.33% in cases where IVP was done, and 41.66% in those who under went LUCS (P<.001). Hospital stay in IVP group was only 1.3 days where as 10 days for those who under went LUCS (P<.001). Regarding complications it was almost same in both groups. IVP was also very cost effective required some of taka 300 only where as for LUCS it required about 3000 taka. Conclusion: The success rate of IVP is good. It is cost effective, preserve the future fertility and prevent DOI: http://dx.doi.org/10.3329/jbcps.v32i1.21030 J Bangladesh Coll Phys Surg 2014; 32: 16-20


2016 ◽  
Vol 48 (5) ◽  
pp. 579-584 ◽  
Author(s):  
J. Man ◽  
J. C. Hutchinson ◽  
A. E. Heazell ◽  
M. Ashworth ◽  
I. Jeffrey ◽  
...  

2016 ◽  
Vol 48 (5) ◽  
pp. 596-601 ◽  
Author(s):  
J. Man ◽  
J. C. Hutchinson ◽  
M. Ashworth ◽  
L. Judge-Kronis ◽  
S. Levine ◽  
...  

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (2) ◽  
pp. 67-73
Author(s):  
T Yu Pestrikova ◽  
E A Yurasova ◽  
I V Yurasov ◽  
A V Kotelnikova

Genital herpes affects all population groups. 98% of the adult population worldwide have antibodies to the herpes simplex virus (HSV-1 or 2). This viral infection is a significant medical and social problem. HSV can lead to a complicated course of pregnancy, causing miscarriages, premature birth, intrauterine fetal death, systemic viral disease in newborns. There is evidence that HSV has a connection with malignant tumors of the prostate and cervix, contributing to their development. This literature review contains modern aspects of epidemiology, etiology, pathogenesis, clinic, diagnosis, treatment of genital herpes, including its recurring forms with valacyclovir (Valvir). Indications for hospitalization of patients with genital herpes were noted and the prognosis of this pathology was determined. The tactics of managing pregnant women with this pathology is presented.


Sign in / Sign up

Export Citation Format

Share Document