More on HTLV-III Antibody Testing in New York City

1986 ◽  
Vol 314 (18) ◽  
pp. 1190-1191
2021 ◽  
Author(s):  
Alexander D Bryan ◽  
Kathleen Tatem ◽  
Jillian Diuguid-Gerber ◽  
Caroline Cooke ◽  
Anya Romanoff ◽  
...  

Objective: Estimate the seroprevalence of SARS-CoV-2 antibodies among New York City Health + Hospitals healthcare workers, and identify demographic and occupational factors associated with SARS-CoV-2 antibodies among healthcare workers. Methods: This was an observational, cross-sectional study using data from SARS-CoV-2 serological tests accompanied by a demographic and occupational survey administered to healthcare workers. Participants were employed by New York City Health + Hospitals (NYC H+H) and either completed serologic testing at NYC H+H between April 30 and June 30, 2020, or completed SARS-CoV-2 antibody testing outside of NYC H+H and were able to self-report results. Results: Seven hundred twenty-seven survey respondents were included in analysis. Participants had a mean age of 46 years (SD= 12.19) and 543 (75%) were women. Two hundred fourteen (29%) participants tested positive or reported testing positive for the presence of SARS-CoV-2 antibodies (IgG+). Characteristics associated with positive SARS-CoV-2 serostatus were Black race (25% IgG+ vs. 15% IgG-, p=0.001), having someone in the household with COVID symptoms (49% IgG+ vs. 21% IgG-, p<0.001), or having a confirmed COVID-19 case in the household (25% IgG+ vs 5% IgG-, p<0.001). Characteristics associated with negative SARS-CoV-2 serostatus included working on a COVID patient floor (27% IgG+ vs. 36% IgG-, p=0.02), working in the ICU (20% IgG+ vs. 28% IgG-, p=0.03), or having close contact with a patient with COVID-19 (51% IgG+ vs. 62% IgG-, p=0.03). Conclusions: Results underscore the significance of community factors and inequities might have on SARS-CoV-2 exposure for healthcare workers.


2012 ◽  
Vol 107 ◽  
pp. S572
Author(s):  
Annika Krystyna ◽  
Robert Tenney ◽  
William Matthew Briggs ◽  
Murray David Schwalb

2013 ◽  
Vol 1 (1) ◽  
pp. 1 ◽  
Author(s):  
Annika Krystyna ◽  
Divya Kumari ◽  
Robert Tenney ◽  
Radomir Kosanovic ◽  
Tarang Safi ◽  
...  

2020 ◽  
Author(s):  
Kathrine Meyers ◽  
Lihong Liu ◽  
Wen-Hsuan Lin ◽  
Yang Luo ◽  
Michael Yin ◽  
...  

Abstract We developed and validated serologic assays to determine SARS-CoV-2 seroprevalence in select patient populations in greater New York City area early during the epidemic. We tested “discarded” serum samples from February 24 to March 29 for antibodies against SARS-CoV-2 spike trimer and nucleocapsid protein. Using known durations for antibody development, incubation period, serial interval, and reproductive ratio for this pandemic, we determined that introduction of SARS-CoV-2 into New York likely occurred between January 23 and February 4, 2020. SARS-CoV-2 spread silently for 4–5 weeks before the first community acquired infection was reported. A novel coronavirus emerged in December 2019 in Wuhan, China1,2 and devasted Hubei Province in early 2020 before spreading to every province within China and nearly every country in the world3. This pathogen, now termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a global pandemic, with ~ 10 million cases and over 500,000 deaths reported through June 30, 20203. The first case of SARS-CoV-2 infection in the United States was identified on January 19, 2020 in a man who returned to the State of Washington from Wuhan4. In the ensuing months, the U.S. has become a hotspot of the pandemic, presently accounting for almost one third of the total caseload and over one fourth of the deaths3. The first confirmed case in New York was reported on March 1 in a traveler recently returned from Iran. The first community-acquired SARS-CoV-2 infection was diagnosed on March 3 in a 50-year-old male who lived in New Rochelle and worked in New York City (https://www1.nyc.gov/site/doh/covid/covid-19-data-archive.page.) In the ensuing 18 weeks, New York City has suffered a peak daily infection number of ~ 4,500 (Fig. 1a) and a cumulative caseload of ~ 400,000 to date. The time period when SARS-CoV-2 gained entry into this epicenter of the pandemic remains unclear.


Author(s):  
Wil Lieberman-Cribbin ◽  
Marta Galanti ◽  
Jeffrey Shaman

Abstract Background We characterized SARS-CoV-2 antibody test prevalence and positive test prevalence across New York City (NYC) in order to investigate disparities in testing outcomes by race and socioeconomic status (SES). Methods Serologic data were downloaded from the NYC Coronavirus data repository (August 2020–December 2020). Area-level characteristics for NYC neighborhoods were downloaded from U.S. census data and a socioeconomic vulnerability index was created. Spatial generalized linear mixed models were performed to examine the association between SES and antibody testing and positivity. Results The proportion of Hispanic population (Posterior Median: 0.001, 95% Credible Interval: 0.0003-0.002), healthcare workers (0.003, 0.0001-0.006), essential workers (0.003, 0.001-0.005), age ≥ 65 years (0.003, 0.00002-0.006), and high SES (SES quartile 3 vs 1: 0.034, 0.003-0.062) were positively associated with antibody tests per 100,000 residents. The White proportion (-0.002, -0.003- -0.001), SES index (quartile 3 vs 1: -0.068, -0.115- -0.017; quartile 4 vs 1: -0.077- -0.134, -0.018) and age ≥ 65 years (-0.005, -0.009- -0.002) were inversely associated with positivity, whereas the Hispanic (0.004, 0.002-0.006), and essential worker proportions (0.008, 0.003-0.012) had positive coefficients. Conclusions Disparities in serologic testing and seropositivity exist on socioeconomic status and race/ethnicity across NYC, indicative of excess COVID-19 burden in vulnerable and marginalized populations.


2014 ◽  
Vol 129 (6) ◽  
pp. 491-495 ◽  
Author(s):  
Victoria Tsai ◽  
Katherine Bornschlegel ◽  
Emily McGibbon ◽  
Stephen Arpadi

1942 ◽  
Vol 74 (3-4) ◽  
pp. 155-162
Author(s):  
H. Kurdian

In 1941 while in New York City I was fortunate enough to purchase an Armenian MS. which I believe will be of interest to students of Eastern Christian iconography.


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