First-Trimester Growth and the Risk of Low Birth Weight

1998 ◽  
Vol 339 (25) ◽  
pp. 1817-1822 ◽  
Author(s):  
Gordon C.S. Smith ◽  
Malcolm F.S. Smith ◽  
Margaret B. McNay ◽  
John E.E. Fleming
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
First Trimester

scholarly journals Investigation of Metronidazole Use during Pregnancy and Adverse Birth Outcomes

2012 ◽  
Vol 56 (9) ◽  
pp. 4800-4805 ◽  
Author(s):  
Catherine A. Koss ◽  
Dana C. Baras ◽  
Sandra D. Lane ◽  
Richard Aubry ◽  
Michele Marcus ◽  
...  
Keyword(s):  
New York ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Congenital Anomalies ◽  
New York State ◽  
Multivariable Analysis ◽  
Preterm Births ◽  
First Trimester ◽  
First Trimester Of Pregnancy

ABSTRACTTo assess whether treatment with metronidazole during pregnancy is associated with preterm birth, low birth weight, or major congenital anomalies, we conducted chart reviews and an analysis of electronic data from a cohort of women delivering at an urban New York State hospital. Of 2,829 singleton/mother pairs, 922 (32.6%) mothers were treated with metronidazole for clinical indications, 348 (12.3%) during the first trimester of pregnancy and 553 (19.5%) in the second or third trimester. There were 333 (11.8%) preterm births, 262 (9.3%) infants of low birth weight, and 52 infants (1.8%) with congenital anomalies. In multivariable analysis, no association was found between metronidazole treatment and preterm birth (odds ratio [OR], 1.02 [95% confidence interval [CI], 0.80 to 1.32]), low birth weight (OR, 1.05 [95% CI, 0.77 to 1.43]), or treatment in the first trimester and congenital anomalies (OR, 0.86 [0.30 to 2.45]). We found no association between metronidazole treatment during the first or later trimesters of pregnancy and preterm birth, low birth weight, or congenital anomalies.

Effect of Maternal Migraine during Gestation and Delivery Outcomes

2021 ◽  
Vol 15 (12) ◽  
pp. 3310-3311
Author(s):  
Maryam Shoaib ◽  
Muhammad Sohail Tareen ◽  
Samia Saifullah ◽  
Fahmida Umar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
First Trimester ◽  
Health Study ◽  
Key Words Migraine ◽  
Visual Aura ◽  
Group I ◽  
Biochemical Status ◽  
Sound Sensitivity ◽  
Term Labour

Background: Migraine is defined as a condition accompanied with head ache, nausea, visual and sound sensitivity. Objective: To determine the effect of migraine on maternal and neonatal health. Study Design: Case control study Place and Duration of Study: Department of Obstetrics & Gynaecology, Sandeman Provincial Hospital, Quetta from 1st August 2018 to 31st August 2021. Methodology: One hundred pregnant women divided into migraine and non-migraine groups were enrolled. Both groups were assessed for their sociodemographic, clinical and biochemical status. Their information was documented. Results: Group I females were above 36 years of age and were in their first trimester. There were 56% women who did not presented visual aura. More irritability, pre-term labour and preeclampsia, risk of C section and hypertension was noticed in group I than Group II. Conclusion: Migraine is linked with higher risk of hypertension, preeclampsia, C section and low birth weight new born. Key words: Migraine, Pregnancy, Low birth weight

Three-dimensional ultrasound first trimester fetal volume measurement and its relation to pregnancy outcome

2017 ◽  
Vol 45 (9) ◽  
Author(s):  
Haitham A. Torky ◽  
Asem A. Moussa ◽  
Ali M. Ahmad ◽  
Osama Dief ◽  
Manar A. Eldesoouky ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnancy Outcome ◽  
Gestational Age ◽  
Preterm Labor ◽  
Three Dimensional ◽  
First Trimester ◽  
3D Ultrasound ◽  
Secondary Outcome ◽  
Crown Rump Length

AbstractAim of work:To determine whether fetal volume (FV) measured by three-dimensional (3D) ultrasound was able to detect fetuses at risk of low birth weight (primary outcome) and/or preterm labor (secondary outcome).Methods:One hundred pregnant women carrying a singleton living pregnancy who were sure of dates, and had a dating scan, with gestational age between 11 weeks and 13 weeks+6 days coming for routine first trimester nuchal translucency (NT) were examined by both two-dimensional (2D) and 3D ultrasound (Vocal System) for crown-rump length (CRL) and FV then followed up regularly every 4 weeks until 28 weeks then biweekly until 36 weeks then weekly until delivery both clinically and by ultrasound biometry.Findings:Eighty-seven cases had a normal outcome, while the remaining 13 cases had either preterm labor (four cases) or low-birth weight (nine cases). FV positively correlated with CRL (P=0.026), gestational age in weeks (P=0.002), neonatal body weight in grams (P=0.018) and neonatal body length at birth (P=0.04). A mean FV of 8.3 mmConclusion:3D assessment of FV in the first trimester provides an accurate method for predicting pregnancy outcome namely low birth weight and neonatal complications, however, it is a better positive predictor than a negative one.

scholarly journals Crown-Rump Length Measured in the Early First Trimester as a Predictor of Low Birth Weight

2013 ◽  
Vol 54 (4) ◽  
pp. 1049 ◽  
Author(s):  
Jae-Yul Kang ◽  
Eun-Ju Park ◽  
Yun-Suk Yang ◽  
Mira Park ◽  
Won I. Park
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
First Trimester ◽  
Crown Rump Length

Effect of stop smoking during the first trimester on Low birth weight: A MCBR Study

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
O Kharkova ◽  
J Odland
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Public Health Problem ◽  
First Trimester ◽  
World Health ◽  
Antenatal Visit ◽  
Smoking During Pregnancy ◽  
Stop Smoking ◽  
Quitting Smoking ◽  
Term Baby

Abstract Background Tobacco smoking is a public health problem. Even though this habit is less common among women than men in Russia, it appears to be on the increase among women aged ≥15 years. Smoking during pregnancy leads to adverse pregnancy and birth outcomes. Compared to the number of studies on maternal smoking and birth weight, the influence of stop smoking on low birth weight is not well documented. The aim of the study was to assess an effect of quitting smoking during the first trimester on low birth weight. Methods The study is based on the Murmansk County Birth registry. Women who delivered a singleton pregnancy after 37 weeks of gestation were comprised to the study (N = 44,486). Smoking information was assessed at the first antenatal visit during pregnancy and self-reported and. Low birth weight was defined in according to the World Health Organization as Mean value minus 2 standard deviations for girls and boys separately. Using logistic regressions, we adjusted for maternal age, residence, ethnicity, education, marital status, alcohol abuse, year of delivery, body mass index, pregnancy diabetes, gestational age, and excessive weight gain. Results The prevalence of low birth weight was 1.1%. This adverse birth outcome was more prevalent in women who smoked during pregnancy (2.5%) in compared to those who stopped do it during pregnancy (0.8%) or did not smoke before and during pregnancy (0.9%) (p < 0.001). Compared to non-smokers, quitting smoking during the first trimester had no significant impact on the low birth weight, even after adjustment for confounders (ORcrude = 0.97 with 95%CI 0.64-1.47 and ORadj = 0.89 with 95%CI 0.58-1.36). Conclusions We observed that women who stop smoking during the first trimester are at no greater risk of having a term baby with low birth weight. Our findings underline a continued need for actions against smoking during pregnancy. Key messages Women who stop smoking during the first trimester are at no greater risk of having a term baby with low birth weight. Our findings underline a continued need for actions against smoking during pregnancy.

A Comparative Study on Serum Levels of Iron, Magnesium, Calcium and Phosphorus during First & Second Trimesters of Pregnancy at a Tertiary Referral Hospital in South India

2021 ◽  
Vol 8 (29) ◽  
pp. 2609-2614
Author(s):  
Pradeep Kumar M ◽  
Mayadevi Brahmanandan ◽  
Dini S.B
Keyword(s):  
Body Mass Index ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Serum Levels ◽  
First Trimester ◽  
Second Trimester ◽  
Mean Values ◽  
Calcium And Phosphorus ◽  
In Pregnancy

BACKGROUND Multiple micronutrient deficiencies commonly coexist in pregnancy and may play a role in the pathogenesis of many high-risk events in pregnancy. Mineral estimation during the first and second trimester may help in the identification of high-risk pregnancies predisposed to pre-eclampsia, preterm birth or low birth weight. Body mass index (BMI) is an independent risk factor influencing the serum levels of micronutrients like iron, calcium, phosphorous and magnesium. The purpose of this study was to compare the serum levels of iron, magnesium, calcium and phosphorus during first & second trimesters of pregnancy and their correlation with body mass index and adverse pregnancy outcomes. METHODS This was a longitudinal descriptive study, done over a period of twelve months, from April 2017 to March 2018. 94 low risk pregnant women were selected in the first trimester, and they were followed up for the entire duration of pregnancy. 2 ml of blood is collected at first and second trimester and analysed for the serum levels of iron (µg/dl), magnesium (mg/dl), calcium (mg/dl) and inorganic phosphorus (mg/dl). Mean values of these elements were noted and BMI was measured. Patients were followed up to observe the pregnancy outcome, especially development of hypertension, preterm birth and low birth weight. The data were subjected to suitable statistical analyses. P value less than 0.05 is considered as statistically significant. RESULTS Mean values of Ca, Mg, inorganic P and Fe were 9.3 mg/dl ± 0.52, 1.79 mg/dl ± 0.28, 3.59 mg/dl ± 0.54 and 83.7 µg/dl ± 25.36 respectively in first trimester and 8.9 mg/dl ± 0.47, 1.62 mg/dl ± 0.16, 3.17 mg/dl ± 0.44 and 76.17 µg/dl ± 21. 69 respectively in the second trimester. Hypocalcaemia was noted in 12.7 % and 38.3 % in the first and second trimester respectively. Hypomagnesaemia was seen in 51.1 % and 80.9 % in the first and second trimester respectively. Hypophosphatemia was seen in 3.2 % and 14.8 % in the first and second trimester respectively. These findings were statistically significant. There was no significant change in the iron levels in the present study. 19.1 % were underweight. 56.4 % had normal BMI. 19.2 % were overweight. 5.3 % were obese. CONCLUSIONS There is no correlation between serum values of trace elements and the BMI of study subjects. Even though significant hypocalcaemia, hypophosphatemia and hypomagnesaemia was noted in second trimester compared to first, there was no predisposition to the development of adverse outcomes like pre-eclampsia, preterm birth or low birth weight. This may be the effect of dietary and pharmacological supplementation during pregnancy. KEYWORDS Micronutrients, Pregnancy Complications, Calcium, Phosphorus, Magnesium, Iron

scholarly journals First trimester use of artemisinin-based combination therapy and the risk of low birth weight and small for gestational age

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Orvalho Augusto ◽  
Andy Stergachis ◽  
Stephanie Dellicour ◽  
Halidou Tinto ◽  
Anifa Valá ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Combination Therapy ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
First Trimester

scholarly journals Obstetrical outcome of pregnancy complicated with first trimester bleeding and subchorionic hematoma

2019 ◽  
Vol 9 (1) ◽  
pp. 23
Author(s):  
Kiran Agarwal ◽  
Ritu . ◽  
Amrita Singh ◽  
Anjali Singh ◽  
Amrita Mishra
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
First Trimester ◽  
Growth Restriction ◽  
Antepartum Haemorrhage ◽  
Increased Risk ◽  
The Difference ◽  
Nicu Admission

Background: First trimester bleeding complicates around 20-27% of pregnancy. Objective of this study was to evaluate and compare the feto-maternal and pregnancy outcome in patients presenting with live pregnancy complicated with first trimester bleeding and subchorionic hematoma with those without subchorionic hematoma.Methods: In this prospective observational study, based on ultrasonography, live pregnancies were categorized into two groups, first group having first trimester bleeding with subchorionic hematoma and second with first trimester bleeding only without any hematoma. They were evaluated for the end outcome of pregnancy in terms of abortion and continuation. Continued pregnancies were evaluated for antenatal complications, delivery and intrapartum events along with fetal outcomes.Results: Outcome of pregnancies presenting with first trimester bleeding in terms of abortion was similar in both the groups, 22.8% and 21.5% with hematoma and without hematoma respectively. Incidence of preeclampsia was 11.4% and Fetal growth restriction was 7% in pregnancies with first trimester bleeding with hematoma and was significantly higher than those without hematoma which was 3.07% for preeclampsia and 3% for fetal growth restriction. Incidence of antepartum haemorrhage was higher in hematoma group but the result was not statistically significant. 20% pregnancies with first trimester bleeding with hematoma had preterm deliveries, while it was 7.7% in pregnancies without hematoma and the difference was statistically significant. Low birth weight had occurred in 20% of babies in first group of patients while 4.6% in second group, difference being statistically significant.Conclusions: We found that live pregnancies with first trimester bleeding and subchorionic hematoma were associated with similar risk of miscarriage and antepartum haemorrhage while increased risk of preeclampsia, fetal growth restrictions, preterm birth, non-reassuring fetal heart pattern, caesarean delivery and low birth weight baby when compared to patients with first trimester bleeding without subchorionic hematoma. There was no difference in 5 minutes Apgar score and the NICU admission in both the groups.

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