A high-performance and flexible chemical structure & data search engine built on CouchDB & ElasticSearch

2018 ◽  
Vol 31 (3) ◽  
pp. 341-349 ◽  
Author(s):  
Ren-zhi Li ◽  
Bo-jie Li ◽  
Guo-zhen Zhang ◽  
Jun Jiang ◽  
Yi Luo
Keyword(s):  
Search Engine ◽  
Structure Data ◽  
High Performance ◽  
Chemical Structure ◽  
Data Search

Direct Growth of Polyaniline Chains from Nitrogen Site of N-Doped Carbon Nanotubes for High Performance Supercapacitor

2014 ◽  
Vol 93 ◽  
pp. 164-167 ◽  
Author(s):  
Joon Won Lim ◽  
Atta Ul Haq ◽  
Sang Ouk Kim
Keyword(s):  
Carbon Nanotubes ◽  
High Performance ◽  
Chemical Structure ◽  
Carbon Materials ◽  
Graphitic Carbon ◽  
Polymer Grafting ◽  
Aniline Monomer ◽  
Defect Site ◽  
Direct Growth ◽  
Grafting From

Polymer grafting from graphitic carbon materials has been explored for several decades. Currently existing methods mostly employ harsh chemical treatment to generate defect site in graphitic carbon plane, which are used as active site for polymerization of precursors. Unfortunately, the treatment cause serious degradation of chemical structure and material properties. Here, we present a straightforward route for growth of polyaniline chain from nitrogen (N)-sites of carbon nanotubes. N site in the CNT wall initiates the polymerization of aniline monomer, which generates seamless hybrids composed of polyaniline directly grafted onto the CNT walls. The synthesized hybrids show excellent synergistic electrochemical performance, and are employed for electrodes of pseudo-capacitor. This approach offers an efficient way to obtain hybrid system consisting of conducting polymers directly grafted from graphitic dopant sites.

scholarly journals METHYL 10-EPI-PHEOPHORBIDE A FROM MCF-7 CELLS ACTIVE LAYER OF THE INDONESIAN FICUS DELTOIDEA JACK LEAVES

2017 ◽  
Vol 9 (8) ◽  
pp. 183 ◽  
Author(s):  
Anggia Murni ◽  
Novriyandi Hanif ◽  
Masaki Kita ◽  
Latifah K. Darusman
Keyword(s):  
Active Layer ◽  
Column Chromatography ◽  
Breast Tumor ◽  
High Performance ◽  
Chemical Structure ◽  
High Resolution Mass Spectrometry ◽  
Assay Method ◽  
Pheophorbide A ◽  
Ficus Deltoidea ◽  
Mcf 7

Objective: To isolate and elucidate a cytotoxic principle against breast tumor MCF-7 cells of the Indonesian terrestrial plant Ficus deltoidea Jack leaves.Methods: F. deltoidea leaves collected at National Park of mount Gede-Pangrango, Indonesia have been subjected to chemical and biological work. F. deltoidea leaves were extracted with 96% aqueous ethanol (EtOH) and was then partitioned into three layers n-hexane, dichloromethane (CH2Cl2), and n-butanol (n-BuOH). All layers were checked for their activity against breast tumor MCF-7 cells using MTT assay method. A portion of the most active layer was purified using open column chromatography to give fraction that has toxicity against zebra fish embryos. Based on the assay-guided isolation, compound 1 was isolated. The chemical structure of 1 was elucidated using nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS) data as well as comparing data with literature.Results: The CH2Cl2 layer of F. deltoidea leaves was found to inhibit breast tumor MCF-7 cells with IC50 10 µg/ml which was the most toxic among the layers. A portion of the most active layer was purified using open column chromatography to give 7 fractions. The fraction 5 showed toxicity against zebrafish embryos (LC50 35 µg/ml, 48 hpf). This fraction was purified using high performance liquid chromatography (HPLC) octadecylsilyl (ODS) column with gradient elution 70% aqueous acetonitrile (MeCN) to 100% MeCN (linear gradient) for 40 min with UV detection at 254 nm (tR = 30.99 min) to give compound 1. The chemical structure of 1 was revealed as a chlorin-type compound named methyl 10-epi-pheophorbide A.Conclusion: Methyl 10-epi-pheophorbide A was isolated for the first time from the active fraction of the Indonesian F. deltoidea leaves or tabat barito. The chemical structure including absolute stereo chemistry was elucidated using NMR and HRMS data as well as by comparison with the literature values. The 13C NMR data has been added to complete the previous report.

Synthesis and Characterization of Fluorinated Alkyl Substituted Disiloxane

2014 ◽  
Vol 529 ◽  
pp. 13-15
Author(s):  
Qing Chuan Xi ◽  
Ke Cao ◽  
Ya Wen Huang ◽  
Guan Jun Chang ◽  
Jun Xiao Yang
Keyword(s):  
High Performance ◽  
Chemical Structure ◽  
Rust Resistance ◽  
Condensation Reaction ◽  
Synthesis And Characterization ◽  
Silicon Oil ◽  
Temperature Performance ◽  
Diffusion Pump ◽  
Measurement Results

Alkyl substituted disiloxanes demonstrated promising applications as high performance hydraulic oil, diffusion pump oil, etc. In this study, fluorinated alkyl substituted disiloxane was synthesized via Grignard reaction followed by condensation reaction. Its chemical structure was verified by FTIR and NMR. Measurement results showed that this silicon oil exhibited good high temperature performance, oxidation resistance and rust resistance.

The GEOSS clearinghouse high performance search engine

2011 ◽  
Author(s):  
Kai Liu ◽  
Chaowei Yang ◽  
Wenwen Li ◽  
Zhenlong Li ◽  
Huayi Wu ◽  
...  
Keyword(s):  
Search Engine ◽  
High Performance

The Production of Jet Fuel From Alternative Sources

1986 ◽  
Vol 108 (4) ◽  
pp. 641-647 ◽  
Author(s):  
H. R. Lander ◽  
H. E. Reif
Keyword(s):  
United States ◽  
High Performance ◽  
Chemical Structure ◽  
Oil Shale ◽  
Rocky Mountain ◽  
Jet Fuel ◽  
Synthetic Fuels ◽  
Potential Source ◽  
Alternative Sources ◽  
Exciting Possibility

The most significant potential source of aviation gas turbine fuels in the continental United States is the western oil shale located in the Rocky Mountain States of Colorado, Utah, and Wyoming. Nearly 600 billion barrels of recoverable oil is located in this area. This paper discusses the availability of oil shale and reviews the recovery, upgrading and refining schemes necessary to produce fuel which can be used in present-day aircraft. Other synthetic fuels are discussed with regard to the processing necessary to produce suitable fuels for today’s high-performance aircraft. Heavy oil and tar sand bitumen are likely to be refined in the next decade. Methods for producing suitable fuels are discussed. The chemical structure of these sources, which is basically cyclic, leads to the potential for heavier fuels with more energy per given volume and therefore longer range for certain aircraft. This exciting possibility is reviewed.

scholarly journals Preparation and Hydro-Lipophilic Properties of Selected Novel Chlorinated and Brominated N-Arylcinnamamides

Proceedings ◽  
2019 ◽  
Vol 41 (1) ◽  
pp. 11
Author(s):  
Tomas Strharsky ◽  
Timotej Jankech ◽  
Jiri Kos ◽  
Kristina Maricakova ◽  
Andrea Pramukova ◽  
...  
Keyword(s):  
High Performance ◽  
Chemical Structure ◽  
Antimicrobial Agents ◽  
Reversed Phase ◽  
Log P ◽  
Organic Modifier ◽  
Chromatography Method ◽  
P Values ◽  
Liquid Chromatography Method ◽  
Derivatives Of

A series of six di- and tri-halogenated N-arylcinnamanilides designed as anti-inflammatory and antimicrobial agents was prepared and characterized. Since it is known that lipophilicity significantly influences the biological activity of compounds, the hydro-lipophilic properties of these di- and tri-substituted N-arylcinnamanilides were investigated in the study. All the discussed derivatives of cinnamic acid were analyzed using the reversed-phase high performance liquid chromatography method to measure lipophilicity. The procedure was performed under isocratic conditions with methanol as an organic modifier in the mobile phase using an end-capped non-polar C18 stationary reversed-phase column. In the present study, the correlations between the logarithm of the capacity factor k and log P/Clog P values calculated in various ways as well as the relationships between the lipophilicity and the chemical structure of the studied compounds are discussed.

scholarly journals Relationships Between Chemical Structure and Antioxidant Activity of Isolated Phytocompounds from Lemon Verbena

Antioxidants ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 324 ◽  
Author(s):  
Noelia Sánchez-Marzo ◽  
Jesús Lozano-Sánchez ◽  
María de la Luz Cádiz-Gurrea ◽  
María Herranz-López ◽  
Vicente Micol ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
High Performance ◽  
Chemical Structure ◽  
Nutrition And Health ◽  
Antioxidant Power ◽  
Lippia Citriodora ◽  
Increasing Demand ◽  
Antioxidant Effects ◽  
Lemon Verbena ◽  
Nutraceutical Products

Over the last few years, people have been concerned about the narrow relationship between nutrition and health leading to an increasing demand of nutraceutical products and functional food. Lemon verbena (Lippia citriodora Kunth) has been traditionally used for respiratory, digestive, and muscular diseases, showing effects that are promoted by the antioxidant activity of its phytoconstituents. The antioxidant power of several lemon verbena extracts has been tested but its isolated compounds activity has not been described. The aim of the present work was to isolate phytochemicals from a commercial lemon verbena extract through a semi-preparative high-performance liquid chromatography approach for further evaluation of its individual antioxidant activity using three different methods. The structure-antioxidant activity relationships revealed the influence of substitutions in the strong antioxidant power exerted by glycosylated phenylpropanoids, in contrast to the low antioxidant capacity showed by iridoids. Development of enriched extracts in these compounds could lead to greater antioxidant effects and improved functional ingredients to prevent chronic diseases.

Sign in / Sign up

Export Citation Format

Share Document