Investigation on photocatalytic properties of RE-Doped titanium dioxide nanoparticles through sol - gel technique

2021 ◽  
Author(s):  
P. Ramesh Babu ◽  
B. Srimathy ◽  
K. Shakila ◽  
M. Lakshmipriya ◽  
R. Arivuselvi
2021 ◽  
Vol 1039 ◽  
pp. 245-252
Author(s):  
Basma Abbas Jabbar ◽  
Khawla J. Tahir ◽  
Basheer M. Hussein ◽  
H.H. Obeed ◽  
Noor J. Ridha ◽  
...  

Europium doped Titanium dioxide (TiO2) nanoparticles were prepared by Sol-Gel technique under varying condition to investigate the effects of Eu3 + doping on the optical properties of Titanium dioxide nanoparticles. The transmittance spectrum is clearly visible at wavelengths 394nm and 416nm, and is a result of electronic transitions of energy level of the Eu3 + ions. . The obtained composites for different doping concentration were analyzed by using Energy Dispersive X-ray Spectroscopy (EDS). The linear and nonlinear optical properties of the composite were studied using the Z-scan technique, and there was an increase in the nonlinear refractive index with an increase in the concentration of the Eu+3, where it reached its highest value, which is 3.01×10-10 at doping 2.3 while the linear absorption coefficient was an inverse proportion, where the highest value was at Pure titanium and it is 1.0296951×10-5 (cm/mw).


Antioxidants ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 880 ◽  
Author(s):  
Chun-Chen Yang ◽  
Chong-Xuan Wang ◽  
Che-Yung Kuan ◽  
Chih-Ying Chi ◽  
Ching-Yun Chen ◽  
...  

Sonodynamic therapy is an effective treatment for eliminating tumor cells by irradiating sonosentitizer in a patient’s body with higher penetration ultrasound and inducing the free radicals. Titanium dioxide has attracted the most attention due to its properties among many nanosensitizers. Hence, in this study, carbon doped titanium dioxide, one of inorganic materials, is applied to avoid the foregoing, and furthermore, carbon doped titanium dioxide is used to generate ROS under ultrasound irradiation to eliminate tumor cells. Spherical carbon doped titanium dioxide nanoparticles are synthesized by the sol-gel process. The forming of C-Ti-O bond may also induce defects in lattice which would be beneficial for the phenomenon of sonoluminescence to improve the effectiveness of sonodynamic therapy. By dint of DCFDA, WST-1, LDH and the Live/Dead test, carbon doped titanium dioxide nanoparticles are shown to be a biocompatible material which may induce ROS radicals to suppress the proliferation of 4T1 breast cancer cells under ultrasound treatment. From in vivo study, carbon doped titanium dioxide nanoparticles activated by ultrasound may inhibit the growth of the 4T1 tumor, and it showed a significant difference between sonodynamic therapy (SDT) and the other groups on the seventh day of the treatment.


Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 625
Author(s):  
Fatma Y. Ahmed ◽  
Usama Farghaly Aly ◽  
Rehab Mahmoud Abd El-Baky ◽  
Nancy G. F. M. Waly

Most of the infections caused by multi-drug resistant (MDR) P. aeruginosa strains are extremely difficult to be treated with conventional antibiotics. Biofilm formation and efflux pumps are recognized as the major antibiotic resistance mechanisms in MDR P. aeruginosa. Biofilm formation by P. aeruginosa depends mainly on the cell-to-cell communication quorum-sensing (QS) systems. Titanium dioxide nanoparticles (TDN) have been used as antimicrobial agents against several microorganisms but have not been reported as an anti-QS agent. This study aims to evaluate the impact of titanium dioxide nanoparticles (TDN) on QS and efflux pump genes expression in MDR P. aeruginosa isolates. The antimicrobial susceptibility of 25 P. aeruginosa isolates were performed by Kirby–Bauer disc diffusion. Titanium dioxide nanoparticles (TDN) were prepared by the sol gel method and characterized by different techniques (DLS, HR-TEM, XRD, and FTIR). The expression of efflux pumps in the MDR isolates was detected by the determination of MICs of different antibiotics in the presence and absence of carbonyl cyanide m-chlorophenylhydrazone (CCCP). Biofilm formation and the antibiofilm activity of TDN were determined using the tissue culture plate method. The effects of TDN on the expression of QS genes and efflux pump genes were tested using real-time polymerase chain reaction (RT-PCR). The average size of the TDNs was 64.77 nm. It was found that TDN showed a significant reduction in biofilm formation (96%) and represented superior antibacterial activity against P. aeruginosa strains in comparison to titanium dioxide powder. In addition, the use of TDN alone or in combination with antibiotics resulted in significant downregulation of the efflux pump genes (MexY, MexB, MexA) and QS-regulated genes (lasR, lasI, rhll, rhlR, pqsA, pqsR) in comparison to the untreated isolate. TDN can increase the therapeutic efficacy of traditional antibiotics by affecting efflux pump expression and quorum-sensing genes controlling biofilm production.


2008 ◽  
Vol 39 (11) ◽  
pp. 1333-1335 ◽  
Author(s):  
Fernando Gordillo Delgado ◽  
Katherine Villa Gómez ◽  
Claudia Mejía Morales

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