Transcriptional Cross-talk between Smad, ERK1/2, and p38 Mitogen-activated Protein Kinase Pathways Regulates Transforming Growth Factor-β-induced Aggrecan Gene Expression in Chondrogenic ATDC5 Cells

Hideto Watanabe; Mark P. de Caestecker; Yoshihiko Yamada

doi:10.1074/jbc.m005724200

Transcriptional Cross-talk between Smad, ERK1/2, and p38 Mitogen-activated Protein Kinase Pathways Regulates Transforming Growth Factor-β-induced Aggrecan Gene Expression in Chondrogenic ATDC5 Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m005724200 ◽

2001 ◽

Vol 276 (17) ◽

pp. 14466-14473 ◽

Cited By ~ 212

Author(s):

Hideto Watanabe ◽

Mark P. de Caestecker ◽

Yoshihiko Yamada

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Protein Kinase ◽

Cross Talk ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein

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Transforming Growth Factor-β-mediated Chondrogenesis of Human Mesenchymal Progenitor Cells Involves N-cadherin and Mitogen-activated Protein Kinase and Wnt Signaling Cross-talk

Journal of Biological Chemistry ◽

10.1074/jbc.m305312200 ◽

2003 ◽

Vol 278 (42) ◽

pp. 41227-41236 ◽

Cited By ~ 342

Author(s):

Richard Tuli ◽

Suraj Tuli ◽

Sumon Nandi ◽

Xiaoxue Huang ◽

Paul A. Manner ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Wnt Signaling ◽

Progenitor Cells ◽

Cross Talk ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Mesenchymal Progenitor Cells ◽

Mitogen Activated Protein

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Involvement of the p38 Mitogen-activated Protein Kinase Pathway in Transforming Growth Factor-β-induced Gene Expression

Journal of Biological Chemistry ◽

10.1074/jbc.274.38.27161 ◽

1999 ◽

Vol 274 (38) ◽

pp. 27161-27167 ◽

Cited By ~ 324

Author(s):

Hiroshi Hanafusa ◽

Jun Ninomiya-Tsuji ◽

Norihisa Masuyama ◽

Michiru Nishita ◽

Jun-ichi Fujisawa ◽

...

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Protein Kinase ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein ◽

Kinase Pathway

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Regulation of Biglycan Gene Expression by Transforming Growth Factor-β Requires MKK6-p38 Mitogen-activated Protein Kinase Signaling Downstream of Smad Signaling

Journal of Biological Chemistry ◽

10.1074/jbc.m300035200 ◽

2003 ◽

Vol 278 (13) ◽

pp. 11041-11049 ◽

Cited By ~ 43

Author(s):

Hendrik Ungefroren ◽

Wolfgang Lenschow ◽

Wen-Bin Chen ◽

Fred Faendrich ◽

Holger Kalthoff

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Protein Kinase ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Smad Signaling ◽

Mitogen Activated Protein ◽

Protein Kinase Signaling

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Expression of human collagenase‐3 (MMP‐13) by fetal skin fibroblasts is induced by transforming growth factor‐β via p38 mitogen‐activated protein kinase

The FASEB Journal ◽

10.1096/fsb2fj000588fje ◽

2000 ◽

Vol 15 (6) ◽

pp. 1098-1100

Author(s):

Laura Ravanti ◽

Mervi Toriseva ◽

Risto Penttinen ◽

Timothy Crombleholme ◽

Marco Foschi ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Skin Fibroblasts ◽

Mitogen Activated Protein Kinase ◽

Fetal Skin ◽

Mitogen Activated Protein

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Transforming Growth Factor-β-induced Osteoblast Elongation Regulates Osteoclastic Bone Resorption through a p38 Mitogen-activated Protein Kinase- and Matrix Metalloproteinase-dependent Pathway

Journal of Biological Chemistry ◽

10.1074/jbc.m008738200 ◽

2001 ◽

Vol 276 (42) ◽

pp. 39350-39358 ◽

Cited By ~ 59

Author(s):

Morten A. Karsdal ◽

Marianne S. Fjording ◽

Niels T. Foged ◽

Jean-Marie Delaissé ◽

André Lochter

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Bone Resorption ◽

Matrix Metalloproteinase ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Osteoclastic Bone Resorption ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein ◽

Dependent Pathway

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Activation of the Mitogen-Activated Protein Kinase Pathway by Transforming Growth Factor-β

Transforming Growth Factor-Beta Protocols ◽

10.1385/1-59259-053-5:125 ◽

2003 ◽

pp. 125-131 ◽

Cited By ~ 4

Author(s):

Jianbo Yue ◽

Kathleen M. Mulder

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein ◽

Kinase Pathway

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Reciprocal Inhibition between the Transforming Growth Factor-β-activated Kinase 1 (TAK1) and Apoptosis Signal-regulating Kinase 1 (ASK1) Mitogen-activated Protein Kinase Kinase Kinases and Its Suppression by TAK1-binding Protein 2 (TAB2), an Adapter Protein for TAK1

Journal of Biological Chemistry ◽

10.1074/jbc.m111.317875 ◽

2011 ◽

Vol 287 (5) ◽

pp. 3381-3391 ◽

Cited By ~ 20

Author(s):

So Yong Kim ◽

Jea-Hyuck Shim ◽

Eunyoung Chun ◽

Ki-Young Lee

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Transforming Growth Factor ◽

Binding Protein ◽

Transforming Growth Factor Β ◽

Reciprocal Inhibition ◽

Mitogen Activated Protein Kinase ◽

Adapter Protein ◽

Mitogen Activated Protein ◽

Protein Kinase Kinase

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Transforming Growth Factor-β-Smad Signaling Pathway Negatively Regulates NontypeableHaemophilus influenzae-inducedMUC5ACMucin Transcription via Mitogen-activated Protein Kinase (MAPK) Phosphatase-1-dependent Inhibition of p38 MAPK

Journal of Biological Chemistry ◽

10.1074/jbc.m301773200 ◽

2003 ◽

Vol 278 (30) ◽

pp. 27811-27819 ◽

Cited By ~ 66

Author(s):

Hirofumi Jono ◽

Haidong Xu ◽

Hirofumi Kai ◽

David J. Lim ◽

Young S. Kim ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Signaling Pathway ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Dependent Inhibition ◽

Mitogen Activated Protein ◽

Smad Signaling Pathway ◽

Mapk Phosphatase

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AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-β-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway

Biochemical Pharmacology ◽

10.1016/j.bcp.2010.06.049 ◽

2010 ◽

Vol 80 (8) ◽

pp. 1210-1220 ◽

Cited By ~ 32

Author(s):

Mei-Ying Chang ◽

Feng-Ming Ho ◽

Jang-Shiun Wang ◽

Hao-Cheng Kang ◽

Yung Chang ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Signaling Pathway ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein ◽

Amp Activated Protein Kinase ◽

Protein Kinase Signaling ◽

Kinase Signaling Pathway

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Expression of human collagenase-3 (MMP-13) by fetal skin fibroblasts is induced by transforming growth factor β via p38 mitogen-activated protein kinase

The FASEB Journal ◽

10.1096/fj.00-0588fje ◽

2001 ◽

Vol 15 (6) ◽

pp. 1098-1100 ◽

Cited By ~ 46

Author(s):

LAURA RAVANTI ◽

MERVI TORISEVA ◽

RISTO PENTTINEN ◽

TIMOTHY CROMBLEHOLME ◽

MARCO FOSCHI ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Skin Fibroblasts ◽

Mitogen Activated Protein Kinase ◽

Fetal Skin ◽

Mitogen Activated Protein

Download Full-text