scholarly journals Unveiling Contacts within Macromolecular Assemblies by Solving Minimum Weight Connectivity Inference (MWC) Problems*

2015 ◽  
Vol 14 (8) ◽  
pp. 2274-2284 ◽  
Author(s):  
Deepesh Agarwal ◽  
Christelle Caillouet ◽  
David Coudert ◽  
Frederic Cazals
Keyword(s):  
Minimum Weight ◽  
Macromolecular Assemblies ◽  
Connectivity Inference

Introduction to Cell Membranes at Molecular Resolution

1978 ◽  
Vol 36 (3) ◽  
pp. 497-502
Author(s):  
R.J. Barrnett
Keyword(s):  
Cell Membranes ◽  
International Federation ◽  
Mountain Range ◽  
Cellular Membranes ◽  
Short History ◽  
Biological Organization ◽  
Macromolecular Assemblies ◽  
The Past

This subject, is like observing the panorama of a mountain range, magnificent towering peaks, but it doesn't take much duration of observation to recognize that they are still in the process of formation. The mountains consist of approaches, materials and methods and the rocky substance of information has accumulated to such a degree that I find myself concentrating on the foothills in the foreground in order to keep up with the advance; the edifices behind form a wonderous, substantive background. It's a short history for such an accumulation and much of it has been moved by the members of the societies that make up this International Federation. My panel of speakers are here to provide what we hope is an interesting scientific fare, based on the fact that there is a continuum of biological organization from biochemical molecules through macromolecular assemblies and cellular membranes to the cell itself. Indeed, this fact explains the whole range of towering peaks that have emerged progressively during the past 25 years.

Multimode light microscopy and fluorescence-based reagents as tools for the study of chemical and molecular dynamics of living cells and tissues

1992 ◽  
Vol 50 (1) ◽  
pp. 418-419
Author(s):  
D. L. Taylor
Keyword(s):  
Living Cells ◽  
Cellular Level ◽  
Molecular Techniques ◽  
Cellular Functions ◽  
Macromolecular Assemblies ◽  
Cell Functions ◽  
Molecular Events ◽  
Yield Information ◽  
Full Knowledge ◽  
Structural Methods

Cells function through the complex temporal and spatial interplay of ions, metabolites, macromolecules and macromolecular assemblies. Biochemical approaches allow the investigator to define the components and the solution chemical reactions that might be involved in cellular functions. Static structural methods can yield information concerning the 2- and 3-D organization of known and unknown cellular constituents. Genetic and molecular techniques are powerful approaches that can alter specific functions through the manipulation of gene products and thus identify necessary components and sequences of molecular events. However, full knowledge of the mechanism of particular cell functions will require direct measurement of the interplay of cellular constituents. Therefore, there has been a need to develop methods that can yield chemical and molecular information in time and space in living cells, while allowing the integration of information from biochemical, molecular and genetic approaches at the cellular level.

Further Studies on the Mechanisms for the Antithrombotic Effects of Sulfated Polysaccharides in Rabbits

1988 ◽  
Vol 60 (02) ◽  
pp. 188-192 ◽  
Author(s):  
F A Ofosu ◽  
F Fernandez ◽  
N Anvari ◽  
C Caranobe ◽  
F Dol ◽  
...  
Keyword(s):  
Antithrombin Iii ◽  
Ex Vivo ◽  
Thrombus Formation ◽  
Minimum Weight ◽  
Sulfated Polysaccharides ◽  
Pentosan Polysulfate ◽  
Heparin Cofactor Ii ◽  
Thrombin Inhibition ◽  
The Relationship ◽  
Prothrombin Activation

SummaryA recent study (Fernandez et al., Thromb. Haemostas. 1987; 57: 286-93) demonstrated that when rabbits were injected with the minimum weight of a variety of glycosaminoglycans required to inhibit tissue factor-induced thrombus formation by —80%, exogenous thrombin was inactivated —twice as fast in the post-treatment plasmas as the pre-treatment plasmas. In this study, we investigated the relationship between inhibition of thrombus formation and the extent of thrombin inhibition ex vivo. We also investigated the relationship between inhibition of thrombus formation and inhibition of prothrombin activation ex vivo. Four sulfated polysaccharides (SPS) which influence coagulation in a variety of ways were used in this study. Unfractionated heparin and the fraction of heparin with high affinity to antithrombin III potentiate the antiproteinase activity of antithrombin III. Pentosan polysulfate potentiates the activity of heparin cofactor II. At less than 10 pg/ml of plasma, all three SPS also inhibit intrinsic prothrombin activation. The fourth agent, dermatan sulfate, potentiates the activity of heparin cofactor II but fails to inhibit intrinsic prothrombin activation even at concentrations which exceed 60 pg/ml of plasma. Inhibition of thrombus formation by each sulfated polysaccharides was linearly related to the extent of thrombin inhibition achieved ex vivo. These observations confirm the utility of catalysis of thrombin inhibition as an index for assessing antithrombotic potential of glycosaminoglycans and other sulfated polysaccharides in rabbits. With the exception of pentosan polysulfate, there was no clear relationship between inhibition of thrombus formation and inhibition of prothrombin activation ex vivo.

CARTECH Ti-3Al-8V-6Cr-4Mo-4Zr (BETA C)

Alloy Digest ◽  
2020 ◽  
Vol 69 (11) ◽  
Keyword(s):  
Corrosion Resistance ◽  
Minimum Weight ◽  
High Strength ◽  
Heat Treating ◽  
Beta Alloy ◽  
Heat Treated ◽  
Technology Corporation ◽  
Carpenter Technology Corporation ◽  
Metastable Beta ◽  
Good Workability

Abstract CarTech Ti-3Al-8V-6Cr-4Mo-4Zr, also known as Ti-3-8-6-4-4 and Beta C, is a metastable beta alloy used in the solution heat treated or solution heat treated and aged condition. It is appropriate for applications where very high strength, minimum weight, and corrosion resistance are important. Ti-3Al-8V-6Cr-4Mo-4Zr has gained in popularity among beta alloys because it is easier to melt and process, exhibiting low segregation, good workability, and good heat-treating properties. This datasheet provides information on composition, physical properties, elasticity, and tensile properties. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: Ti-172. Producer or source: Carpenter Technology Corporation.

The identification of minimum-weight sound packages

2018 ◽  
Vol 66 (6) ◽  
pp. 523-540 ◽  
Author(s):  
Hyunjun Shin ◽  
J. Stuart Bolton
Keyword(s):  
Minimum Weight

scholarly journals Quadruple Roman Domination in Trees

Symmetry ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1318
Author(s):  
Zheng Kou ◽  
Saeed Kosari ◽  
Guoliang Hao ◽  
Jafar Amjadi ◽  
Nesa Khalili
Keyword(s):  
Open Neighborhood ◽  
Minimum Weight ◽  
Domination Number ◽  
Theoretical Computer Science ◽  
Upper And Lower Bounds ◽  
Discrete Mathematics ◽  
Roman Domination ◽  
Roman Domination Number ◽  
Vertex Set ◽  
Roman Dominating Function

This paper is devoted to the study of the quadruple Roman domination in trees, and it is a contribution to the Special Issue “Theoretical computer science and discrete mathematics” of Symmetry. For any positive integer k, a [k]-Roman dominating function ([k]-RDF) of a simple graph G is a function from the vertex set V of G to the set {0,1,2,…,k+1} if for any vertex u∈V with f(u)<k, ∑x∈N(u)∪{u}f(x)≥|{x∈N(u):f(x)≥1}|+k, where N(u) is the open neighborhood of u. The weight of a [k]-RDF is the value Σv∈Vf(v). The minimum weight of a [k]-RDF is called the [k]-Roman domination number γ[kR](G) of G. In this paper, we establish sharp upper and lower bounds on γ[4R](T) for nontrivial trees T and characterize extremal trees.

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