scholarly journals The effect of ‘fibre-filler’ (F-plan diet) on iron, zinc and calcium absorption in rats

1985 ◽  
Vol 54 (3) ◽  
pp. 585-592 ◽  
Author(s):  
Susan J. Fairweather-Tail ◽  
A. J. A. Wright
Keyword(s):  
Calcium Absorption ◽  
Ferrous Sulphate ◽  
Whole Body ◽  
Fibre Filler ◽  
Long Term Effect ◽  
Blood Haemoglobin ◽  
Body Counting ◽  
Whole Body Counting ◽  
Zn Availability

1. The availability of iron, zinc and calcium in a diet containing 400 g ‘fibre-filler’ (a mixture of bran, fruit and nuts, used in the F-plan diet)/kg diet (HF diet) was measured by whole-body counting in rats, using 59Fe, 66Zn and 47Ca as extrinsic labels, and compared with a diet of similar mineral content but no ‘fibre-filler’ (LF diet). Absorption of Fe and Ca was significantly higher from the HF than from the LF diet but there was no difference in Zn availability between the two diets.2. The ability of rats given LF or HF diets for 3 or 28 d to absorb Fe, Zn and Ca was measured using ferrous sulphate, zinc chloride and calcium chloride in a cooked starch-sucrose (1: 1 w/w) paste, extrinsically-labelled with the appropriate isotope. There was no difference in Fe absorption between the HF- and LF-fed groups but both Zn and Ca absorption were higher in LF- than in HF-fed animals after 3 and 28 d.3. The mineral status of the animals given HF or LF diets for 28 d was examined, and there were no differences in blood haemoglobin, liver and bone Zn and plasma and bone Ca levels. The total liver Fe was significantly lower (P < 0.05) in the HF-fed animals.4. It was concluded that ‘fibre-filler’did not have an adverse effect on Fe, Zn or Ca metabolism in rats although the long-term effect on Fe status warrants more detailed investigation. Further work is required to extend these studies to man.

Studies of Calcium Absorption in Man Using a CD-2 Whole-Body Counter

1977 ◽  
Vol 16 (04) ◽  
pp. 163-167
Author(s):  
K. Bakos ◽  
Věra Wernischová
Keyword(s):  
Calcium Absorption ◽  
Whole Body ◽  
Control Group ◽  
Absorption Process ◽  
Whole Body Counter ◽  
Absorption Studies ◽  
Body Counting ◽  
Calcium Load ◽  
Calcium Malabsorption ◽  
Whole Body Counting

SummaryWhole-body counting makes an important contribution of radioisotope techniques to ȁEin vivo“ absorption studies, in comparison with other methods. In a large number of subjects, the method was tested for its usefulness in the diagnosis of calcium malabsorption. The effects of drugs, of the calcium load in the gut and of the whole-body content of calcium on the absorption process were studied in a control group.

Long-Term Clearance of [57Co]Cyanocobalamin in Vegans and Pernicious Anaemia

1980 ◽  
Vol 58 (1) ◽  
pp. 101-103 ◽  
Author(s):  
S. Amin ◽  
T. Spinks ◽  
A. Ranicar ◽  
M. D. Short ◽  
A. V. Hoffbrand
Keyword(s):  
Intrinsic Factor ◽  
Pernicious Anaemia ◽  
Normal Subjects ◽  
Whole Body ◽  
Least Squares Fit ◽  
Significant Difference ◽  
Maximum Period ◽  
Body Counting ◽  
Whole Body Counting

1. Whole-body counting has been used to monitor the clearance of [57Co]cyanocobalamin in normal subjects, vegans and patients with pernicious anaemia. After oral administration of 57Colabelled cyanocobalamin (1 μg/l μCi), subjects were counted for radioactivity monthly for a maximum period of 1 year. 2. The results obtained were consistent with a monoexponential clearance model and a least-squares fit showed that there was no significant difference between the mean clearance rates for the vegans and normal subjects. 3. The patients with pernicious anaemia cleared the vitamin significantly more quickly than the normal control subjects. 4. This may be due to failure to reabsorb biliary vitamin B12 in pernicious anaemia because of the absence of intrinsic factor.

Mono ferrous acid citrate (FeC6O7H2O) as an iron fortificant

1978 ◽  
Vol 39 (3) ◽  
pp. 663-665 ◽  
Author(s):  
B. S. Narasinga Rao ◽  
Soonita Kathoke ◽  
S. V. Apte
Keyword(s):  
Wheat Flour ◽  
Iron Absorption ◽  
Ferrous Sulphate ◽  
Whole Body ◽  
Healthy Male ◽  
Male And Female ◽  
Ferrous Citrate ◽  
Body Counting ◽  
Colour Development ◽  
Whole Body Counting

1. Iron absorption from ferrous citrate (monoferrous acid citrate, FeC6H6O7H2O) was studied in normal healthy male and female volunteers using ferrous citrate labelled with radioactive Fe and whole-body counting. Ferrous citrate was either given alone or with a rice-based meal.2. Fe absorption from ferrous citrate was satisfactory and was comparable to that from ferrous sulphate.3. Fortification of crude cooking salt with ferrous citrate was not satisfactory due to colour development on storage. Ferrous citrate can, however, serve as an effective Fe fortificant with sugar or wheat flour.

A Modified Chair Geometry for Whole Body Counting

1976 ◽  
Vol 15 (05) ◽  
pp. 246-247
Author(s):  
S. C. Jain ◽  
G. C. Bhola ◽  
A. Nagaratnam ◽  
M. M. Gupta
Keyword(s):  
Marked Improvement ◽  
Point Of View ◽  
Whole Body ◽  
Spatial Response ◽  
Body Counting ◽  
The Subject ◽  
Whole Body Counting ◽  
The Buddha

SummaryIn the Marinelli chair, a geometry widely used in whole body counting, the lower part of the leg is seen quite inefficiently by the detector. The present paper describes an attempt to modify the standard chair geometry to minimise this limitation. The subject sits crossed-legged in the “Buddha Posture” in the standard chair. Studies with humanoid phantoms and a volunteer sitting in the Buddha posture show that this modification brings marked improvement over the Marinelli chair both from the point of view of sensitivity and uniformity of spatial response.

Body potassium by four-pi 40K counting: an anthropometric correction

1984 ◽  
Vol 246 (2) ◽  
pp. F234-F239 ◽  
Author(s):  
R. N. Pierson ◽  
J. Wang ◽  
J. C. Thornton ◽  
T. B. Van Itallie ◽  
E. W. Colt
Keyword(s):  
Adipose Tissue ◽  
Single Crystal ◽  
Covariance Analysis ◽  
Whole Body ◽  
Exchangeable Sodium ◽  
Independent Evidence ◽  
Body Counting ◽  
Whole Body Counting

Four-pi whole body counting for the 1.46 meV photon of 40K has apparent advantages over single-crystal or two-pi counters in efficiency and in subject geometry independence. However, our studies of obese populations have disclosed a systematic undermeasurement of 40K, suggesting that nonhomogeneous K distribution results in systematic undercounting of 40K. In the current study 42K, emitting a 1.52 meV photon, was used in 109 volunteers ranging from 50 to 181 kg, and multiregression covariance analysis was applied to develop correction formulas based on anthropometrics. These corrections quantitatively account for the unappreciated loss of 40K and 42K photons in annular adipose tissue that surrounds the lean body, in which most K+ is concentrated. The correction ranges from 1 to 28% and is a linear (although different) function of weight in both sexes. Thus corrected, body potassium measurements, taken in conjunction with exchangeable sodium and water measurements, provide estimates for whole body osmolality that match measured serum values. Such a quantitative accounting for previously "lost" cation in 58 subjects provides independent evidence for the appropriateness and accuracy of the correction. With this correction, body potassium was recalculated in the 1,492 adult members of a previously reported group of 3,083 subjects.

Whole Body Counting of Vitamin B12 58Co Absorption Supplemented by Profile Scanning

1970 ◽  
Vol 5 (4) ◽  
pp. 261-264
Author(s):  
N. D. C. Finlayson ◽  
J. D. Simpson ◽  
D. J. C. Shearman
Keyword(s):  
Vitamin B12 ◽  
Whole Body ◽  
Body Counting ◽  
Whole Body Counting
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