Porcine epidemic diarrhoea virus in the USA: lessons learned from the 2013 outbreak.

2014 ◽  
Vol 9 (042) ◽  
Author(s):  
J Lowe
Keyword(s):  
Lessons Learned ◽  
Porcine Epidemic Diarrhoea Virus ◽  
Diarrhoea Virus ◽  
The Usa

scholarly journals Current status of porcine epidemic diarrhoea (PED) in European pigs

2019 ◽  
Vol 63 (4) ◽  
pp. 465-470
Author(s):  
Marta Antas ◽  
Grzegorz Woźniakowski
Keyword(s):  
Rna Virus ◽  
Acute Diarrhoea ◽  
Current Status ◽  
Economic Losses ◽  
Porcine Epidemic Diarrhoea Virus ◽  
Diarrhoea Virus ◽  
The Us ◽  
The Usa ◽  
Suckling Piglets ◽  
Farming Industry

Abstract Porcine epidemic diarrhoea (PED) is a highly contagious and devastating enteric disease of pigs caused by porcine epidemic diarrhoea virus (PEDV), an enveloped, single-stranded RNA virus belonging to the Alphacoronavirus genus of the Coronaviridae family. The disease is clinically similar to other forms of porcine gastroenteritis. Pigs are the only known host of the disease, and the occurrence of PED in wild boars is unknown. The virus causes acute diarrhoea, vomiting, dehydration, and high mortality in suckling piglets reaching 100%. Heavy economic losses in the pig-farming industry were sustained in the USA between 2013 and 2015 when PEDV spread very quickly and resulted in epidemics. The loss in the US pig industry has been estimated at almost seven million pigs. The purpose of this review is a description of the current status of porcine epidemic diarrhoea in European pigs and the risk presented by the introduction of PEDV to Poland in comparison to the epidemics in the USA.

Reflecting or ruminating: listening to the regrets of life science leaders

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Helen Mary Meldrum
Keyword(s):  
Chief Executive Officers ◽  
Life Science ◽  
Negative Emotion ◽  
Chief Executive ◽  
Positive Influence ◽  
Lessons Learned ◽  
Business Leaders ◽  
Content Type ◽  
The Usa ◽  
Executive Officers

PurposeThe overwhelming frequency of failure in trying to bring a safe and effective biotech, pharmaceutical or medical device product to market is truly astounding. This research synthesizes industry leaders' insights on lessons learned from reflecting on professional disappointments.Design/methodology/approachThis research used a qualitative approach to learning from the Chief Executive Officers (CEOs), Chief Scientific Officers (CSOs) and Chief Medical Officers (CMOs) of the most successful life science firms in the USA. A total of 45 industry leaders were interviewed regarding their lingering regrets about their career misadventures.FindingsRegrets were unavoidable because there were opportunity costs for every choice each leader made. Commentary about wisdom gained comprised themes regarding valuable time lost, strategies that could have been enacted, products that failed and essential personnel who were not managed optimally. Contrary to expectations, there was little mention of money that was squandered.Originality/valueNot felt as a solely negative emotion, regrets were recognized by these leaders as a potentially positive influence on their future decisions. Not felt as a solely negative emotion, regret was recognized by these leaders as a potentially positive influence on their future decisions. This exploratory study suggests that learning from retrospective and anticipated regrets benefits life science leaders in gaining clarity of thought regarding their current business challenges. Because prior research on the value of psychological regrets has mostly relied on limited samples, this inquiry contributes a new vantage point by examining a unique population of senior business leaders, thus providing broader applicability to the organizational literature.

Implementing a Geohazard Integrity Management Program: Statistics and Lessons Learned Over 15 Years

2014 ◽  
Author(s):  
Alex J. Baumgard ◽  
Tara L. Coultish ◽  
Gerry W. Ferris
Keyword(s):  
Management System ◽  
Management Program ◽  
Lessons Learned ◽  
Proactive Approach ◽  
Oil Pipelines ◽  
Pipeline Networks ◽  
The Usa ◽  
Integrity Management ◽  
Pipeline Failures ◽  
Program Challenges

Over the last 15 years, BGC Engineering Inc. has developed and implemented a geohazards Integrity Management Program (IMP) with 12 major pipeline operators (consisting of gas and oil pipelines and of both gathering and transmission systems). Over this time, the program has been applied to the assessment of approximately 13,500 individual hydrotechnical and geotechnical geohazard sites spanning approximately 63,000 km of operating pipelines in Canada and the USA. Hydrotechnical (watercourse) and geotechnical (slope) hazards are the primary types of geohazards that have directly contributed to pipeline failures in Canada. As with all IMPs, the core objectives of a geohazard management system are to ensure a proactive approach that is repeatable and defensible. In order to meet these objectives, the program allows for varying levels of intensity of inspection and a recommended timescale for completion of actions to manage the identified geohazards in accordance with the degree of hazard that the site poses to the pipeline. In this way, the sites are managed in a proactive manner while remaining flexible to accommodate the most current conditions at each site. This paper will provide a background to the key components of the program related specifically to existing operating pipeline systems, present pertinent statistics on the occurrence of various types of geohazards based on the large dataset of inspections, and discuss some of the lessons learned in the form of program results and program challenges from implementing a geohazard integrity management system for a dozen operators with different ages of systems, complexity of pipeline networks, and in varied geographic settings.

scholarly journals Molecular characterization of porcine epidemic diarrhoea virus (PEDV) in Poland reveals the presence of swine enteric coronavirus (SeCoV) sequence in S gene

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258318
Author(s):  
Marta Antas ◽  
Monika Olech ◽  
Anna Szczotka-Bochniarz
Keyword(s):  
Phylogenetic Analysis ◽  
Molecular Characterization ◽  
Rna Virus ◽  
Economic Losses ◽  
High Morbidity ◽  
Antigenic Analysis ◽  
S Gene ◽  
Porcine Epidemic Diarrhoea Virus ◽  
Diarrhoea Virus

Porcine epidemic diarrhoea (PED) is a highly contagious enteric viral disease of pigs with a high morbidity and mortality rate, which ultimately results in huge economic losses in the pig production sector. The etiological agent of this disease is the porcine epidemic diarrhoea virus (PEDV) which is an enveloped, positive single-stranded RNA virus. The aim of this study was to perform molecular characterization of PEDV to identify the strains circulating in Poland. In this study, 662 faecal samples from 2015 to 2021 were tested with reverse transcription quantitative real-time PCR (RT-qPCR) and the results showed that 3.8% of the tested samples revealed a positive result for PEDV. A phylogenetic analysis of the complete genome and complete S gene sequences showed that Polish PEDV strains belonged to the G1b (S-INDEL) subgroup and were closely related to the European PEDV strains isolated from 2014 to 2019. Furthermore, RDP4 analysis revealed that the Polish PEDV strains harboured a recombinant fragment of ~400 nt in the 5’ end of S gene with PEDV and swine enteric coronavirus (SeCoV) being the major and minor parents, respectively. Antigenic analysis showed that the aa sequences of neutralizing epitopes were conserved among the Polish PEDV strains. Only one strain, #0100/5P, had a unique substitution in the COE epitope. However, Polish PEDV strains showed several substitutions, especially in the COE antigen, as compared to the classical strain CV777. To the best of our knowledge, this is the first report concerning the molecular characterization of porcine epidemic diarrhoea virus strains, as well as the first phylogenetic analysis for PEDV in Poland.

The African American Tobacco Control Leadership Council: Advocating for a menthol cigarette ban in San Francisco, California

2021 ◽  
pp. tobaccocontrol-2020-056215
Author(s):  
Sarah D Mills ◽  
Carol O McGruder ◽  
Valerie B Yerger
Keyword(s):  
African American ◽  
Tobacco Control ◽  
San Francisco ◽  
Community Support ◽  
Control Policy ◽  
Tobacco Product ◽  
Lessons Learned ◽  
Menthol Cigarette ◽  
The Usa ◽  
Product Sales

The African American Tobacco Control Leadership Council (AATCLC) is an advocacy group that works to inform the direction of tobacco control policy and priorities in the USA. This article narrates the AATCLC’s work advocating for a comprehensive, flavoured tobacco product sales ban in San Francisco, California. Recommendations for tobacco control advocates and lessons learned from their work are provided. The article concludes by discussing conditions necessary to enact the policy. These include having a dedicated advocacy team, community support, a policy sponsor, and clear and repeated messaging that is responsive to community concerns.

BIM Based Design Management of a Building Project Collaboratively Designed With a Foreign Design Firm in China

2019 ◽  
pp. 902-927
Author(s):  
Algan Tezel ◽  
Zeeshan Aziz ◽  
Chuxiong Jiang
Keyword(s):  
Building Design ◽  
Lessons Learned ◽  
Design Management ◽  
Construction Market ◽  
Stakeholder Perspectives ◽  
Building Information ◽  
The Usa ◽  
Complex Building ◽  
Design Firms ◽  
Building Project

In parallel with China's growing construction market, there has been an influx of foreign architectural and engineering design firms into the Chinese construction market. Those firms generally form partnerships with local Chinese firms or institutions to overcome various complications in the country. Adding to the complexity, relatively recent technologies such as Building Information Modelling (BIM) also started to play a role in those collaborative project design management efforts in China. This paper presents an in-depth case study of a complex building design project collaboratively executed using BIM by a foreign design firm from the USA and local Chinese firm in China. The project was analysed from different design management and stakeholder perspectives. Some of the findings confirm the pervious accounts from the literature. New insights and the key lessons learned for BIM based design management in this context are also presented.

Innovation Adoption and Adaptation in Air Traffic Control

2012 ◽  
Vol 4 (1) ◽  
pp. 17-29
Author(s):  
Tatjana Bolic
Keyword(s):  
Traffic Control ◽  
Air Traffic Control ◽  
Innovation Process ◽  
Innovation Adoption ◽  
Air Travel ◽  
Air Traffic ◽  
Lessons Learned ◽  
Evaluation Tool ◽  
User Request ◽  
The Usa

With the increased demand for the air travel the air traffic control (ATC) systems have been improving over the years. Today, the advances in the technology can enable even more capacity and better performance for the air travel. With those goals in mind, two distinct, but similar programmes are striving to develop new ATC systems: Next Gen in the USA and SESAR programme in Europe. Both programmes aim at developing new systems for the implementation around the year 2020. The innovation adoption and adaptation is illustrated by the story of User Request Evaluation Tool development and implementation, followed by the discussion of main lessons. First, the lessons learned from the innovation process of the tool itself are discussed, to be followed by the discussion of the interaction of various organizations that were involved.

Building multifunctionality into agricultural conservation programs: lessons learned from designing agroforestry systems with central Illinois landowners

2019 ◽  
Vol 35 (3) ◽  
pp. 313-321 ◽  
Author(s):  
Erik Christian Stanek ◽  
Sarah Taylor Lovell
Keyword(s):  
Design Process ◽  
Collaborative Design ◽  
Crop Production ◽  
Conservation Policy ◽  
Agroforestry Systems ◽  
Agricultural Landscapes ◽  
Lessons Learned ◽  
Conservation Programs ◽  
Multifunctional Landscapes ◽  
The Usa

AbstractSince 1985, land retirement has been the primary approach used by the federal government for environmental protection of agricultural landscapes, but increasingly it is being supplemented by conservation initiatives on working lands. This shift logically supports agroforestry and other multifunctional approaches as a means to combine production and conservation. However, such approaches can be complex and difficult to design, contributing to the limited adoption in the USA. To understand and improve the integration of multifunctional landscapes into conservation programs, we worked with 15 landowners in a collaborative design process to build unique conservation plans utilizing agroforestry. We interviewed participants before and after the design process to examine the utility of a personalized design process, applicability of agroforestry to conservation programs and pathways to improve conservation policy. We found that landowners strongly preferred working in person for the design process, and being presented a comparison of alternative designs, rather than a single option, especially for novel systems. Agroforestry was seen as a viable method of generating conservation benefits while providing value to the landowners, each of whom stated they were more inclined to adopt such practices irrespective of financial assistance to do so. For conservation programs, landowners suggested reducing their complexity, inflexibility and impersonal nature to improve the integration of multifunctional practices that appeal directly to the practitioner's needs and preferences. These findings are valuable for conservation policy because they complement previous research theory suggesting the value of working collaboratively with landowners in the design of multifunctional landscapes. Personalized solutions that are developed based on the unique characteristics of the local landscape and the preferences of the individual landowner may be retained beyond a specified payment period, rather than being converted back into annual crop production.

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