The role of cytomegalovirus colitis on short- and long-term outcomes for patients with ulcerative colitis

Pancreatic cancer with synchronous liver metastasis has an extremely poor prognosis, and surgery is not recommended for such patients by the current guidelines. However, an increasing body of studies have shown that concurrent resection of pancreatic cancer and liver metastasis is not only technically feasible but also beneficial to the survival in the selected patients. In this review, we aim to summarize the short- and long-term outcomes following synchronous liver metastasectomy for pancreatic cancer patients, and discuss the potential criteria in selecting appropriate surgical candidates, which might be helpful in clinical decision-making.

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Diabetes in Pregnancy and MicroRNAs: Promises and Limitations in Their Clinical Application

Non-Coding RNA ◽

10.3390/ncrna4040032 ◽

2018 ◽

Vol 4 (4) ◽

pp. 32 ◽

Cited By ~ 6

Author(s):

Adriana Ibarra ◽

Begoña Vega-Guedes ◽

Yeray Brito-Casillas ◽

Ana Wägner

Keyword(s):

Gestational Diabetes ◽

Maternal Diabetes ◽

Long Term Outcomes ◽

Pregnant Rats ◽

Diagnostic Biomarkers ◽

Obesity And Diabetes ◽

Increased Risk ◽

Short And Long Term

Maternal diabetes is associated with an increased risk of complications for the mother and her offspring. The latter have an increased risk of foetal macrosomia, hypoglycaemia, respiratory distress syndrome, preterm delivery, malformations and mortality but also of life-long development of obesity and diabetes. Epigenetics have been proposed as an explanation for this long-term risk, and microRNAs (miRNAs) may play a role, both in short- and long-term outcomes. Gestation is associated with increasing maternal insulin resistance, as well as β-cell expansion, to account for the increased insulin needs and studies performed in pregnant rats support a role of miRNAs in this expansion. Furthermore, several miRNAs are involved in pancreatic embryonic development. On the other hand, maternal diabetes is associated with changes in miRNA both in maternal and in foetal tissues. This review aims to summarise the existing knowledge on miRNAs in gestational and pre-gestational diabetes, both as diagnostic biomarkers and as mechanistic players, in the development of gestational diabetes itself and also of short- and long-term complications for the mother and her offspring.

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Sa1946 Factors Associated With the First Trough Level of Infliximab at Week 2 That Predicts Short- and Long-Term Outcomes in Ulcerative Colitis

Gastroenterology ◽

10.1016/s0016-5085(16)31434-2 ◽

2016 ◽

Vol 150 (4) ◽

pp. S412

Author(s):

Taku Kobayashi ◽

Yasuo Suzuki ◽

Satoshi Motoya ◽

Fumihito Hirai ◽

Haruhiko Ogata ◽

...

Keyword(s):

Ulcerative Colitis ◽

Trough Level ◽

Long Term Outcomes ◽

Factors Associated ◽

Short And Long Term

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OP030. Factors associated with the first trough level of infliximab at week 2 that predicts short- and long-term outcomes in ulcerative colitis

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjw019.029 ◽

2016 ◽

Vol 10 (suppl 1) ◽

pp. S24.2-S25

Keyword(s):

Ulcerative Colitis ◽

Trough Level ◽

Long Term Outcomes ◽

Factors Associated ◽

Short And Long Term

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Short- and Long-Term Outcomes of Infliximab Treatment for Refractory Ulcerative Colitis and Related Prognostic Factors: A Japanese Single-Center Study

Inflammatory Bowel Diseases ◽

10.1097/00054725-201212001-00084 ◽

2012 ◽

Vol 18 ◽

pp. S36

Author(s):

Hiroki Tanaka ◽

Masaki Yamashita ◽

Manabu Ishii ◽

Satoshi Motoya ◽

Akimichi Imamura

Keyword(s):

Ulcerative Colitis ◽

Prognostic Factors ◽

Infliximab Treatment ◽

Single Center ◽

Long Term Outcomes ◽

Single Center Study ◽

Short And Long Term ◽

Center Study

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The role of public health in addressing child maltreatment in Canada

Chronic Diseases in Canada ◽

10.24095/hpcdp.31.1.07 ◽

2010 ◽

Vol 31 (1) ◽

pp. 39-44 ◽

Cited By ~ 5

Author(s):

SM Jack

Keyword(s):

Public Health ◽

Child Maltreatment ◽

Surveillance Systems ◽

Long Term Outcomes ◽

Community Based Interventions ◽

Community Based ◽

Complex Issue ◽

Short And Long Term

Child maltreatment is a significant health and social issue given its prevalence across the general population and the significant short- and long-term outcomes associated with maltreatment in childhood. There is a need for a comprehensive, collaborative and multisectoral approach for identification, prevention and intervention of this complex issue. Within this multisectoral collaboration, it is essential for public health in Canada to define its role in addressing and preventing child maltreatment. This commentary summarizes how public health can address the issue of child maltreatment in Canada by specifically: 1) measuring the magnitude of maltreatment through public health surveillance systems such as the Canadian Incidence Study of Reported Child Abuse and Neglect; 2) identifying modifiable risk factors; 3) identifying and evaluating community-based interventions to prevent violence; and 4) implementing evidence-based primary prevention strategies.

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