Antibiotic Susceptibility Patterns of Community- and Hospital-acquired Staphylococcus aureus and Escherichia coli in Estonia

2001 ◽  
Vol 33 (5) ◽  
pp. 333-338 ◽  
Author(s):  
Tõnis Karki, Kai Truusalu, Inga Vai
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibiotic Susceptibility ◽  
Antibiotic Susceptibility Patterns ◽  
Hospital Acquired ◽  
Susceptibility Patterns

scholarly journals Staphylococcus aureus nasal carriage in the community: a survey from central Italy

2002 ◽  
Vol 129 (2) ◽  
pp. 417-420 ◽  
Author(s):  
G. ZANELLI ◽  
A. SANSONI ◽  
A. ZANCHI ◽  
S. CRESTI ◽  
S. POLLINI ◽  
...  
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Antibiotic Susceptibility ◽  
Central Italy ◽  
Rare Event ◽  
Nasal Carriage ◽  
High Rate ◽  
Methicillin Resistant ◽  
Antibiotic Susceptibility Patterns ◽  
Susceptibility Patterns

Recently, concern has increased regarding the spread of methicillin-resistant Staphylococcus aureus (MRSA) in the community. We studied 812 subjects from central Italy to establish the rates of nasal carriage of S. aureus, and antibiotic susceptibility patterns, in the community. The prevalence of S. aureus nasal carriage was 30.5%. Only one subject, with predisposing risk factors for acquisition, was identified as carrier of MRSA (prevalence of 0.12%). The presence of MRSA in the community of our area still appears to be a rare event. Among methicillin-susceptible S. aureus (MSSA) isolates, a surprisingly high rate (18%) of resistance to rifampin was observed.

scholarly journals Comparative Molecular Analysis of Community- or Hospital-Acquired Methicillin-Resistant Staphylococcus aureus

2003 ◽  
Vol 47 (1) ◽  
pp. 196-203 ◽  
Author(s):  
P. D. Fey ◽  
B. Saïd-Salim ◽  
M. E. Rupp ◽  
S. H. Hinrichs ◽  
D. J. Boxrud ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Genetic Relatedness ◽  
Health Concern ◽  
Toxic Shock ◽  
Methicillin Resistant ◽  
Type Iv ◽  
Antibiotic Susceptibility Patterns ◽  
Mrsa Strains ◽  
Hospital Acquired ◽  
Susceptibility Patterns

ABSTRACT Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing public health concern that has been associated with pediatric fatalities. It is hypothesized that the evolution of CA-MRSA is a recent event due to the acquisition of mec DNA by previously methicillin-susceptible strains that circulated in the community. This study investigated the genetic relatedness between CA-MRSA, hospital-associated MRSA (HA-MRSA), and nonmenstrual toxic shock syndrome (nmTSS) isolates. Thirty-one of 32 CA-MRSA isolates were highly related as determined by pulsed-field gel electrophoresis and spa typing yet were distinguishable from 32 HA-MRSA strains. The 31 related CA-MRSA isolates produced either staphylococcal enterotoxin B (n = 5) or C (n = 26), and none made TSS toxin 1. All CA-MRSA isolates tested contained a type IV staphylococcal cassette chromosome mec (SCCmec) element. In comparison, none of the HA-MRSA isolates (n = 32) expressed the three superantigens. Antibiotic susceptibility patterns were different between the CA-MRSA and HA-MRSA isolates; CA-MRSA was typically resistant only to β-lactam antibiotics. Six of twenty-one nmTSS isolates were indistinguishable or highly related to the CA-MRSA isolates. MnCop, an nmTSS isolate obtained in Alabama in 1986, was highly related to the CA-MRSA isolates except that it did not contain an SCCmec element. These data suggest that CA-MRSA strains may represent a new acquisition of SCCmec DNA in a previously susceptible genetic background that was capable of causing nmTSS. CA-MRSA poses a serious health risk not only because it is resistant to the antibiotics of choice for community-acquired staphylococcal infections but also because of its ability to cause nmTSS via superantigen production.

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