Platelet-Rich Plasma Outcomes Do Not Correlate with Patient Satisfaction or Perceived Cost-Effectiveness

2022 ◽  
Author(s):  
Edward Stephan. Mojica ◽  
Charles Lin ◽  
Noah Kirschner ◽  
Paola Ortega ◽  
Eoghan T. Hurley ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
Cost Effectiveness ◽  
Platelet Rich Plasma

Fractional carbon dioxide laser, platelet –rich plasma and narrow band ultraviolet B in the treatment of Vitiligo (A prospective randomized comparative trial)

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohamed Abdullah Eshafi ◽  
Nehal Mohamed Zuelfakkar ◽  
Ahmed Abd Elfattah Afify
Keyword(s):  
Patient Satisfaction ◽  
Co2 Laser ◽  
Platelet Rich Plasma ◽  
Ultraviolet B ◽  
Treatment Modalities ◽  
Computer Assisted ◽  
Triple Combination ◽  
Patient Satisfaction Score ◽  
Triple Combination Therapy ◽  
Melanin Pigmentation

Abstract Vitiligo is a disease that causes the loss of skin color in patches due to loss of melanin pigmentation of specific areas of the skin. Although several hypotheses have been proposed, the leading theory is still the auto-immune etiology linked to specific genetic mutations. Vitiligo can also be associated with several autoimmune diseases. There is no curative treatment for vitiligo but, several treatment modalities are considered. Topical therapies like steroids and Calcineurin inhibitors are of popular use in clinical settings also, steroids can be administered systemically in vitiligo patients. Physical therapies as fractionated CO2 (Fr: CO2) laser and Narrowband-UV (NBUV) phototherapy represent a gold standard in treatment in clinical practice. Moreover, intralesional therapies are emerging, one of which is autologous platelet-rich plasma injection. Aim of the study This study aimed to evaluate and compare the efficacy and safety of Fr: CO2 laser, PRP, combined Fr: CO2 laser and PRP, combined Fr: CO2 laser and NB-UVB, combined Fr: CO2 laser, PRP and NB-UVB in the treatment of vitiligo as well as reporting the side effects. Patients and methods This study included 20 vitiligo patients with at least 6 patches of stable vitiligo (120 patches), the patches were divided into six groups according to the treatment modality. Assessment of treatment response was done through patient satisfaction score and Vitiligo analysis by computer-assisted grid (VACAG). Results Regarding surface area reduction in included patients, fractional CO2 laser achieved the best results followed by triple combination therapy (CO2 with PRP and NB-UVB), the least response was with CO2 with PRP treatment. Patient satisfaction in the current study had a different outcome, PRP treated patients exhibited the highest satisfaction scores while triple combination treated group showed the least satisfaction scores.

scholarly journals Role of platelet-rich plasma in the treatment of osteoarthritis: a meta-analysis

2020 ◽  
Vol 48 (10) ◽  
pp. 030006052096466
Author(s):  
Haijiang Ren ◽  
Shouwei Zhang ◽  
Xuejie Wang ◽  
Zehui Li ◽  
Wenlai Guo
Keyword(s):  
Patient Satisfaction ◽  
Clinical Efficacy ◽  
Platelet Rich Plasma ◽  
Meta Analysis ◽  
Womac Score ◽  
Cochrane Library ◽  
Control Group ◽  
Absolute Value ◽  
Vas Score ◽  
The Absolute

Objective The clinical efficacy of platelet-rich plasma (PRP) in the treatment of osteoarthritis remains controversial. In this paper, we evaluated the clinical efficacy of PRP in the treatment of osteoarthritis using meta-analysis, providing evidence for the selection of clinical treatment options. Methods We performed a computer-based search of PubMed, Embase, and the Cochrane Library databases to retrieve articles using the search terms “platelet-rich plasma”, “osteoarthrosis”, and “knee joint”. Quality evaluation and data extraction were performed. The combined effect was assessed using RevMan 5.3 software. Results Five randomized controlled trials, involving 320 patients, were included in this study. No significant differences were observed in the International Knee Documentation Committee score, visual analog scale (VAS) score, or the absolute value of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score between the experimental and control groups. The absolute value of the VAS score and change in the WOMAC score were significantly decreased and patient satisfaction was increased in the experimental group, as compared with the control group. Conclusion The findings of this meta-analysis suggest that intra-articular injection of PRP is an effective treatment for osteoarthritis that can reduce post-operative pain, improve locomotor function, and increase patient satisfaction.

Telemedicine: Patient Satisfaction and Cost-Effectiveness

2006 ◽  
Vol 27 (Supplement) ◽  
pp. S142
Author(s):  
D M. Mertens ◽  
R J. Kagan ◽  
P Warner
Keyword(s):  
Patient Satisfaction ◽  
Cost Effectiveness

Cost-effectiveness of Prophylactic Antiemetic Therapy with Ondansetron, Droperidol, or Placebo

2000 ◽  
Vol 92 (4) ◽  
pp. 958-967 ◽  
Author(s):  
Robert P. Hill ◽  
David A. Lubarsky ◽  
Barbara Phillips-Bute ◽  
Jennifer T. Fortney ◽  
Mary R. Creed ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
Cost Effectiveness ◽  
High Risk ◽  
Pharmacoeconomic Analysis ◽  
Healthcare Delivery ◽  
Postoperative Nausea And Vomiting ◽  
Antiemetic Therapy ◽  
Labor Costs ◽  
Clinical Practices ◽  
Enflurane Anesthesia

Background In an era of growing economic constraints on healthcare delivery, anesthesiologists are increasingly expected to understand cost analysis and evaluate clinical practices. Postoperative nausea and vomiting (PONV) are distressing for patients and may increase costs in an ambulatory surgical unit. The authors compared the cost-effectiveness of four prophylactic intravenous regimens for PONV: 4 mg ondansetron, 0.625 mg droperidol, 1.25 mg droperidol, and placebo. Methods Adult surgical outpatients at high risk for PONV were studied. Study drugs were administered intravenously within 20 min of induction of nitrous oxide-isoflurane or enflurane anesthesia. A decision-tree analysis was used to group patients into 12 mutually exclusive subgroups based on treatment and outcome. Costs were calculated for the prevention and treatment of PONV. Cost-effectiveness analysis was performed for each group. Results Two thousand sixty-one patients were enrolled. Efficacy data for study drugs have been previously reported, and the database from that study was used for pharmacoeconomic analysis. The mean-median total cost per patient who received prophylactic treatment with 4 mg ondansetron, 0.625 mg droperidol, 1.25 mg droperidol, and placebo were $112 or $16.44, $109 or $0.63, $104 or $0.51, and $164 or $51.20, respectively (P = 0.001, active treatment groups vs. placebo). The use of a prophylactic antiemetic agent significantly increased patient satisfaction (P < 0.05). Personnel costs in managing PONV and unexpected hospital admission constitute major cost components in our analysis. Exclusion of nursing labor costs from the calculation did not alter the overall conclusions regarding the relative costs of antiemetic therapy. Conclusion The use of prophylactic antiemetic therapy in high-risk ambulatory surgical patients was more effective in preventing PONV and achieved greater patient satisfaction at a lower cost compared with placebo. The use of 1.25 mg droperidol intravenously was associated with greater effectiveness, lower costs, and similar patient satisfaction compared with 0.625 mg droperidol intravenously and 4 mg ondansetron intravenously.

scholarly journals Efficacy of Platelet-rich Plasma for Low Back Pain: A Systematic Review and Meta-analysis

2020 ◽  
Vol 81 (06) ◽  
pp. 529-534 ◽  
Author(s):  
Zhaopeng Xuan ◽  
Wenjun Yu ◽  
Yichen Dou ◽  
Tao Wang
Keyword(s):  
Systematic Review ◽  
Low Back Pain ◽  
Patient Satisfaction ◽  
Back Pain ◽  
Pain Relief ◽  
Platelet Rich Plasma ◽  
Meta Analysis ◽  
Low Back ◽  
Pain Scores ◽  
Control Intervention

Abstract Background Platelet-rich plasma (PRP) may be beneficial for patients with low back pain. However, the results remain controversial. We conducted a systematic review and meta-analysis to explore the efficacy of PRP for low back pain. Methods PubMed, Embase, Web of Science, EBSCO, and Cochrane Library databases were searched systematically. Randomized controlled trials (RCTs) assessing the effect of PRP on low back pain were included. Two investigators independently searched articles, extracted data, and assessed the quality of included studies. The primary outcome was pain scores within 8 weeks. Meta-analysis was performed using the random-effects model. Results Three RCTs involving 131 patients were included in the meta-analysis. Overall, compared with control intervention for low back pain, PRP injection was found to reduce pain scores significantly (mean difference: − 1.47; 95% confidence interval [CI], − 2.12 to − 0.81; p < 0.0001), improve the number of patients with > 50% pain relief at 3 months (risk ratio [RR]: 4.14; 95% CI, 2.22–7.74; p < 0.00001), and offer relatively good patient satisfaction (RR: 1.91; 95% CI, 1.04–3.53; p = 0.04). No increase in adverse events was reported after PRP injection (RR: 1.92; 95% CI, 0.94-3.91; p = 0.07). Conclusions Compared with control intervention for low back pain, PRP injection was found to improve pain relief and patient satisfaction significantly with no increase in adverse events.

Review the Evidence for Structured Education in Diabetes Management

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Sumon Rahman Chowdhury
Keyword(s):  
Quality Of Life ◽  
Patient Satisfaction ◽  
Cost Effectiveness ◽  
Total Cholesterol ◽  
Diabetes Management ◽  
Diabetic Patients ◽  
Medical Outcomes ◽  
Education Programs ◽  
Structured Education

Structured Education is of detrimental importance for the management, counseling, and prevention of complications in diabetic patients. Different structured education programs exist that significantly improves the quality of life in diabetic patients as well as improves psychosocial outcomes by enhancing self-empowerment and self-motivation. Improvements have also been noted in bio-medical outcomes as a result of structured education most significantly in HbA1C, total cholesterol and frequency of hypoglycemia. In order to ensure patient satisfaction and improve outcomes related to complications, it is very important to identify and support patients whose psychosocial situations and reactions to the diagnosis may affect their ability to adjust or take adequate responsibility for self-care early in the course of the disease. In this review, we will discuss and highlight the evidence that support the benefits, limitations, and cost effectiveness of structured education in diabetes management.

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