Cognitive hyper-dissonance: Nuclear signaling through military exercises

2021 ◽  
Vol 40 (5) ◽  
pp. 423-454
Author(s):  
James Blackwell
2021 ◽  
Vol 16 (1) ◽  
pp. 208-225
Author(s):  
D.N. NECHAEV ◽  
◽  
T.N. BUKREEVA ◽  

The purpose of the article is to determine the main prerequisites for the development of Russian-Chinese anti-terrorist cooperation, to study the international treaty base that determines the priority areas of bilateral interaction, based on the dynamics of joint anti-terrorist activities, to propose a periodization of interaction between the two countries in the area under study. The research methodology is based on a systematic analysis of bilateral cooperation between Russia and China in countering terrorism. In the course of the study, the authors analyzed the treaty base within the framework of this topic, the UN reports on terrorism and the FATF recommendations for Russia and China. As a result, on the basis of the proposed periodization, it is demonstrated that Russian-Chinese bilateral cooperation in the fight against terrorism is of an applied systemic nature and is fine-tuned in the areas of holding consultative meetings, countering the financing of terrorist activities and organizing joint military exercises. The authors revealed that the problematic area of interaction is the exchange of operational information in the framework of terrorist financing, associated with the unwillingness of the Chinese side to provide relevant information at their disposal. In conclusion, it is proved that it is advisable to expand cooperation between Russia and China in the fight against international terrorism in the direction of countering non-standard challenges and threats to the information space, biological origin, chemical impact and environmental nature.


Circulation ◽  
2000 ◽  
Vol 102 (17) ◽  
pp. 2111-2117 ◽  
Author(s):  
Filomena de Nigris ◽  
Tammam Youssef ◽  
SilviaAnna Ciafré ◽  
Flavia Franconi ◽  
Vittorio Anania ◽  
...  

2021 ◽  
pp. 54
Author(s):  
Andrey V. Rusakovich

In 2021, Russia and Belarus are planning to hold a record number of exercises. In particular, large-scale strategic maneuvers "West-2021" will be held on the territory of Belarus. The focus on the western borders is not accidental: according to the military ministers of the two countries, the situation there is not calm. At the level of the CSTO, NATO is active in Eastern Europe in building up the missile defense system and increasing the intensity of military exercises. According to Secretary General of the organization Stanislav Zasya, the confrontational course of the alliance creates dangerous preconditions for a new arms race and the alliance is forced "to take adequate measures. Andrei Rusakovich, professor of Belarussian State University, explained in an interview with Eurasia.Expert why Russia and Belarus are increasing military cooperation and how cooperation within the CSTO fits into these tasks.


2019 ◽  
Author(s):  
Marcus J. C. Long ◽  
Yi Zhao ◽  
Yimon Aye

SummaryRibonucleotide reductase (RNR) is an essential enzyme in DNA-biogenesis and a target of several chemotherapeutics. Here we investigate how anti-leukemic drugs [e.g., clofarabine (ClF)] that target one of the two subunits of RNR, RNR-α, affect non-canonical RNR-α functions. We discovered that these clinically-approved RNR-inhibiting dATP-analogs inhibit growth by also targeting ZRANB3—a newly-identified DNA-synthesis promoter and nuclear-localized interactor of RNR-α. Remarkably, in early time points following drug treatment, ZRANB3-targeting accounted for most of the drug-induced DNA-synthesis suppression and multiple cell types featuring ZRANB3-knockout/knockdown were resistant to these drugs. Additionally, ZRANB3 plays a major role in regulating tumor-invasion and H-rasG12V-promoted transformation in a manner dependent on the recently-discovered interactome of RNR-α involving select cytosolic-/nuclear-localized protein-players. The H-rasG12V-promoted transformation—which we show requires ZRANB3-supported DNA-synthesis—was efficiently suppressed by ClF. Such overlooked mechanisms-of-action of approved drugs and a new example of non-oncogene addiction, which is suppressed by RNR-α, may advance cancer interventions.


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