scholarly journals Complete genome sequencing and assessment of mutation-associated protein dynamics of the first Indian bovine ephemeral fever virus (BEFV) isolate

2021 ◽  
pp. 1-16
Author(s):  
Shruti Pyasi ◽  
Advika Gupta ◽  
Nagendra R. Hegde ◽  
Debasis Nayak
Keyword(s):  
Protein Dynamics ◽  
Genome Sequencing ◽  
Complete Genome ◽  
Fever Virus ◽  
Bovine Ephemeral Fever Virus ◽  
Complete Genome Sequencing ◽  
Bovine Ephemeral Fever

scholarly journals Complete Genome Sequencing and Genetic Characterization of Alkhumra Hemorrhagic Fever Virus Isolated from Najran, Saudi Arabia

Intervirology ◽  
2014 ◽  
Vol 57 (5) ◽  
pp. 300-310 ◽  
Author(s):  
Tariq A. Madani ◽  
Esam I. Azhar ◽  
El-Tayeb M.E. Abuelzein ◽  
Moujahed Kao ◽  
Hussein M.S. Al-Bar ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Genome Sequencing ◽  
Complete Genome ◽  
Genetic Characterization ◽  
Hemorrhagic Fever ◽  
Fever Virus ◽  
Complete Genome Sequencing ◽  
Hemorrhagic Fever Virus

scholarly journals Complete Genome Sequence of a Bovine Ephemeral Fever Virus Isolate from Israel

2019 ◽  
Vol 8 (41) ◽  
Author(s):  
Daniel L. W. Dorey-Robinson ◽  
Mar Fernández de Marco ◽  
Luis M. Hernández-Triana ◽  
Arran J. Folly ◽  
Lorraine M. McElhinney ◽  
...  
Keyword(s):  
Complete Genome Sequence ◽  
Complete Genome ◽  
Virus Isolate ◽  
Genomic Sequence ◽  
Fever Virus ◽  
Open Reading Frames ◽  
Genome Sequences ◽  
Bovine Ephemeral Fever Virus ◽  
Bovine Ephemeral Fever ◽  
Reading Frames

Here, we report the first complete genome of a bovine ephemeral fever virus (BEFV) isolate from an infected bovine in Israel. The genome shares 95.3% identity with a Turkish genomic sequence but contains α3 and γ open reading frames that are truncated compared to those of existing BEFV genome sequences.

Complete genome sequence of a bovine ephemeral fever virus JT02L strain in mainland China

2017 ◽  
Vol 162 (11) ◽  
pp. 3555-3558 ◽  
Author(s):  
Shandian Gao ◽  
Junzheng Du ◽  
Zhancheng Tian ◽  
Qingli Niu ◽  
Fuying Zheng ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Mainland China ◽  
Fever Virus ◽  
Bovine Ephemeral Fever Virus ◽  
Bovine Ephemeral Fever

Complete genome analysis of highly pathogenic bovine ephemeral fever virus isolated in Turkey in 2012

2017 ◽  
Vol 162 (10) ◽  
pp. 3233-3238 ◽  
Author(s):  
Hasan Abayli ◽  
Sukru Tonbak ◽  
Ahmet Kursat Azkur ◽  
Hakan Bulut
Keyword(s):  
Genome Analysis ◽  
Complete Genome ◽  
Fever Virus ◽  
Bovine Ephemeral Fever Virus ◽  
Highly Pathogenic ◽  
Bovine Ephemeral Fever ◽  
Complete Genome Analysis

Influence of using of saponin-carbopol mixture adjuvant on the potency of freeze-dried Bovine Ephemeral Fever virus vaccine

2019 ◽  
Vol 2 (4) ◽  
pp. 47-60
Author(s):  
Zeinab, T. Salem ◽  
Shendy, M. B. ◽  
Omaima, A. El-Shemindy ◽  
Soliman, A. F. ◽  
Naglaa ,I. Aly
Keyword(s):  
Virus Vaccine ◽  
Fever Virus ◽  
Bovine Ephemeral Fever Virus ◽  
Bovine Ephemeral Fever ◽  
Freeze Dried

scholarly journals A Senescence-Like Cellular Response Inhibits Bovine Ephemeral Fever Virus Proliferation

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 601
Author(s):  
Yu-Jing Zeng ◽  
Min-Kung Hsu ◽  
Chiao-An Tsai ◽  
Chun-Yen Chu ◽  
Hsing-Chieh Wu ◽  
...  
Keyword(s):  
Virus Infection ◽  
Cellular Response ◽  
Cell Clone ◽  
Fever Virus ◽  
Gene Set Enrichment Analysis ◽  
Host Cells ◽  
Scale Production ◽  
Bovine Ephemeral Fever Virus ◽  
Virus Growth ◽  
Bovine Ephemeral Fever

During industrial-scale production of viruses for vaccine manufacturing, anti-viral response of host cells can dampen maximal viral antigen yield. In addition to interferon responses, many other cellular responses, such as the AMPK signaling pathway or senescence-like response may inhibit or slow down virus amplification in the cell culture system. In this study, we first performed a Gene Set Enrichment Analysis of the whole-genome mRNA transcriptome and found a senescence-like cellular response in BHK-21 cells when infected with bovine ephemeral fever virus (BEFV). To demonstrate that this senescence-like state may reduce virus growth, BHK-21 subclones showing varying degrees of a senescence-like state were infected with BEFV. The results showed that the BHK-21 subclones showing high senescence staining could inhibit BEFV replication while low senescence-staining subclones are permissive to virus replication. Using a different approach, a senescence-like state was induced in BHK-21 using a small molecule, camptothecin (CPT), and BEFV susceptibility were examined. The results showed that CPT-treated BHK-21 is more resistant to virus infection. Overall, these results indicate that a senescence-like response may be at play in BHK-21 upon virus infection. Furthermore, cell clone selection and modulating treatments using small molecules may be tools in countering anti-viral responses.

Isolation and genetic characterization of bovine ephemeral fever virus from epidemic-2020 in Turkey

2021 ◽  
Vol 53 (2) ◽  
Author(s):  
Ilke Karayel-Hacioglu ◽  
Selda Duran Yelken ◽  
Yaser Vezir ◽  
Nilay Unal ◽  
Feray Alkan
Keyword(s):  
Genetic Characterization ◽  
Fever Virus ◽  
Bovine Ephemeral Fever Virus ◽  
Bovine Ephemeral Fever
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