Design of experiments and multivariate analysis approach to study dissolution stability of a modified-release drug product to support lean design strategies

2021 ◽  
pp. 1-30
Author(s):  
Nika Jordan ◽  
Robert Roškar ◽  
Iztok Grabnar
Keyword(s):  
Multivariate Analysis ◽  
Design Of Experiments ◽  
Drug Product ◽  
Analysis Approach ◽  
Modified Release ◽  
Design Strategies ◽  
Release Drug

Scientific and Regulatory Considerations in Solid Oral Modified Release Drug Product Development

2016 ◽  
Vol 18 (6) ◽  
pp. 1406-1417 ◽  
Author(s):  
Min Li ◽  
Sanna Sander ◽  
John Duan ◽  
Susan Rosencrance ◽  
Sarah Pope Miksinski ◽  
...  
Keyword(s):  
Product Development ◽  
Drug Product ◽  
Modified Release ◽  
Release Drug

Hydrogels for modified-release drug delivery systems

2021 ◽  
Vol 28 ◽  
Author(s):  
Aleksandra Zielińska ◽  
Piotr Eder ◽  
Lucas Rannier ◽  
Juliana C. Cardoso ◽  
Patrícia Severino ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Drug Delivery Systems ◽  
Search Strategy ◽  
Delivery Systems ◽  
Global Market ◽  
Modified Release ◽  
Safety And Efficacy ◽  
Area Of Interest ◽  
Release Drug

Abstract: Hydrogels for the modified-release drug delivery systems is a continuously growing area of interest for the pharmaceutical industry. According to the global market, the use of polymers in this area is projected to reach $31.4 million by 2027. This review discusses the recent advances and perspectives of hydrogel in drug delivery systems for oral, parenteral, nasal, topical, and ophthalmic. The search strategy did in January 2021, and it conducted an extensive database to identify studies published from January 2010 to December 2020.We described the main characteristic of the polymers to obtain an ideal hydrogel for a specific route of administration and the formulations that was a highlight in the literature. It concluded that the hydrogels are a set useful to decrease the number of doses, side effects, promote adhesion of patient and enhances the bioavailability of the drugs improving the safety and efficacy of the treatment.

A Multivariate Analysis Approach to Diamonds’ Pricing Using Dummy Variables in SPSS

2021 ◽  
pp. 609-623
Author(s):  
Ana Rita Antunes ◽  
Cláudia Buga Buga ◽  
Daniel Coutinho Costa ◽  
José Grilo ◽  
Ana Cristina Braga ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Analysis Approach ◽  
Dummy Variables

Choosing internal standards based on a multivariate analysis approach with ICP(TOF)MS

2008 ◽  
Vol 23 (9) ◽  
pp. 1214 ◽  
Author(s):  
Haley J. Finley-Jones ◽  
John L. Molloy ◽  
James A. Holcombe
Keyword(s):  
Multivariate Analysis ◽  
Analysis Approach ◽  
Internal Standards ◽  
Tof Ms

A multivariate analysis approach to the integration of proteomic and gene expression data

PROTEOMICS ◽  
2007 ◽  
Vol 7 (13) ◽  
pp. 2162-2171 ◽  
Author(s):  
Ailís Fagan ◽  
Aedín C. Culhane ◽  
Desmond G. Higgins
Keyword(s):  
Gene Expression ◽  
Multivariate Analysis ◽  
Gene Expression Data ◽  
Analysis Approach ◽  
Expression Data

Functionality improvement of Chlorzoxazone by crystallo-co-agglomeration using multivariate analysis approach

2020 ◽  
pp. 1-23
Author(s):  
Mihir K. Raval ◽  
Kevin C. Garala ◽  
Jaydeep M. Patel ◽  
Rajesh K. Parikh ◽  
Navin R. Sheth
Keyword(s):  
Multivariate Analysis ◽  
Analysis Approach
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