Preparation, material properties and antimicrobial efficacy of silicone hydrogel by modulating silicone and hydrophilic monomer

2019 ◽  
Vol 30 (12) ◽  
pp. 1050-1067
Author(s):  
Hsiu-Wen Chien ◽  
Chia-Jung Kuo
2012 ◽  
Vol 38 (6) ◽  
pp. 350-357 ◽  
Author(s):  
J. Angelo Green ◽  
K. Scott Phillips ◽  
Victoria M. Hitchins ◽  
Anne D. Lucas ◽  
Megan E. Shoff ◽  
...  

2019 ◽  
Vol 6 (4) ◽  
pp. 94
Author(s):  
Joshua Moore ◽  
Bernardo T. Lopes ◽  
Ashkan Eliasy ◽  
Brendan Geraghty ◽  
Richard Wu ◽  
...  

Purpose: To evaluate the variation in the optical power achieved following soft contact lens eye fitting for spherical and cylindrical lenses with differing hydrogel material properties. Methods: Uniaxial tensile tests were performed on four hydrogel materials 77% water-content (w-c) hydrogel, 74% w-c blue silicone hydrogel, 74% w-c clear silicone hydrogel, and 64% w-c clear hydrogel (shortly referred to as H77p0, SiH74p5-blue, SiH74p5-clear, and H64p0-clear), under loading conditions that would be expected in vivo. Finite element models of the cornea and contact lens interaction were generated using spherical and cylindrical lenses with powers varying from −10 to +20 D; overall diameters of either 13.5, 14.0, or 14.5 mm; and with material properties matching those determined through experimental testing. Results: The moduli of elasticity for each of the tested hydrogel materials were 0.195 ± 0.027 MPa, 0.277 ± 0.019 MPa, 0.279 ± 0.01 MPa, and 0.457 ± 0.013 MPa for H77p0, SiH74p5-blue, SiH74p5-clear, and H64p0 respectively. The calculated values of effective power change (EPC) showed strong negative correlations with lens power. This was particularly apparent in the higher end of the lens power spectrum (over +5 D), where each of the materials demonstrated a highly linear reduction in EPC with increased lens power. Conclusions: Soft contact lenses composed of a stiffer hydrogel are far more resilient to changes in EPC across the lower end of the lens power spectrum (−10 to +5 D). Beyond this range, the material choice does not have a significant effect on the EPC.


Author(s):  
C.L. Briant

Grain boundary segregation is the process by which solute elements in a material diffuse to the grain boundaries, become trapped there, and increase their local concentration at the boundary over that in the bulk. As a result of this process this local concentration of the segregant at the grain boundary can be many orders of magnitude greater than the bulk concentration of the segregant. The importance of this problem lies in the fact that grain boundary segregation can affect many material properties such as fracture, corrosion, and grain growth.One of the best ways to study grain boundary segregation is with Auger electron spectroscopy. This spectroscopy is an extremely surface sensitive technique. When it is used to study grain boundary segregation the sample must first be fractured intergranularly in the high vacuum spectrometer. This fracture surface is then the one that is analyzed. The development of scanning Auger spectrometers have allowed researchers to first image the fracture surface that is created and then to perform analyses on individual grain boundaries.


Author(s):  
Brian Ralph ◽  
Barlow Claire ◽  
Nicola Ecob

This brief review seeks to summarize some of the main property changes which may be induced by altering the grain structure of materials. Where appropriate an interpretation is given of these changes in terms of current theories of grain boundary structure, and some examples from current studies are presented at the end of this paper.


Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
HH Alfa ◽  
R Arroo ◽  
S Walsh ◽  
K Ruparelia ◽  
A Bhambra ◽  
...  

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