Nutritional status is associated with the degree of cognitive impairment and depressive symptoms in a Greek elderly population

BackgroundAlthough the prevalence of malnutrition is relatively low among elderly people, the risk increases significantly among inpatients and even more in those with mental deterioration.AimsTo evaluate the possible association between the severity of depressive symptoms, the nutritional status and the cognitive decline in a sample of geriatric inpatients.MethodsFifty-one geriatric inpatients completed the following tests:– Hamilton Depression Rating Scale (HAM-D), to assess the severity of depressive symptoms;– Mini Nutritional Assessment (MNA), as a nutrition screening and assessment tool;– Mini Mental State Examination (MMSE), to assess the cognitive impairment.ResultsThere is a negative proportional relationship between HAM-D and MMSE scores (P = 0.001) and between HAM-D and MNA scores (P = 0.023). Depressed patients found to have a greater cognitive impairment and a worse nutritional status. Considering a HAM-D cut-off point of 14, distinguishing mild than moderate depression, it shows a significant correlation with the MNA scores (P = 0.008). Patients with HAM-D scores ≥ 14 have an average MNA score of 19.8, while patients with HAM-D scores < 14 have an MNA average score of 23.6. Euthymic or mildly depressed patients are not at risk of malnutrition, while those with moderate or severe depression have an increased risk of malnutrition.ConclusionsOur study shows significant correlations between the severity of depressive symptoms and the risk of malnutrition or cognitive impairment. A mild depression state does not seem to be associated with an increased risk of malnutrition.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Depressive Symptoms Predict Cognitive Decline in an Elderly Non Disabled Population with White Matter Changes. Results of the LADIS Study

European Psychiatry ◽

10.1016/s0924-9338(09)70423-7 ◽

2009 ◽

Vol 24 (S1) ◽

pp. 1-1

Author(s):

A. Verdelho ◽

S. Madureira ◽

C. Moleiro ◽

J.M. Ferro

Keyword(s):

Cognitive Impairment ◽

Depressive Symptoms ◽

White Matter ◽

Cognitive Decline ◽

Elderly Population ◽

Depression Scale ◽

Elderly Subjects ◽

White Matter Changes ◽

The Impact ◽

Independent Elderly

Aims:Depressive symptoms (DS) in the elderly have been implicated in cognitive decline, and are more frequent in patients with white matter changes (WMC). Our aim was to ascertain if DS influence cognition in an elderly population with WMC.Methods:The LADIS (Leukoaraiosis and Disability) is a prospective European study that evaluates the impact of WMC on the transition of independent elderly subjects into disability. Subjects were enrolled due to minor complaints without impact in daily-living activities, and presence of WMC. Subjects were evaluated at baseline and yearly during 3 years with a comprehensive clinical and functional protocol. DS were recorded with the Geriatric Depression Scale (GDS). Major depression was classified according to the DSM-IV criteria. Dementia and cognitive decline not dementia were diagnosed according to usual clinical criteria. MRI was performed at entry and at the end of the study. WMC severity was rated according to the Fazeka's scale.Results:639 subjects were included (74.1 ± 5 years old, 55% women, 9.6±3.8 years of schooling). 89% (568), 78.4% (501), and 75% (480) of the patients from the initial sample were followed-up in clinical visit at year 1, 2 and 3. At the end of the study 90 patients were demented and 147 patients had cognitive impairment not dementia. Using survival Cox regression we found that depressive symptoms were independent predictors of cognitive impairment independently of age, education, gender, WMC severity and temporal atrophy.Conclusion:Depressive symptoms are independent predictor of cognitive decline in an independent elderly population with WMC.

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The relationship of current depressive symptoms and past depression with cognitive impairment and instrumental activities of daily living in an elderly population: The Sydney Memory and Ageing Study

Journal of Psychiatric Research ◽

10.1016/j.jpsychires.2011.08.001 ◽

2011 ◽

Vol 45 (12) ◽

pp. 1600-1607 ◽

Cited By ~ 32

Author(s):

S. Reppermund ◽

H. Brodaty ◽

J.D. Crawford ◽

N.A. Kochan ◽

M.J. Slavin ◽

...

Keyword(s):

Cognitive Impairment ◽

Depressive Symptoms ◽

Activities Of Daily Living ◽

Daily Living ◽

Elderly Population ◽

Instrumental Activities ◽

Ageing Study ◽

Relationship Of ◽

The Relationship

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Depressive symptoms, cognitive impairment and functional impairment in a rural elderly population in India: a Hindi version of the geriatric depression scale (GDS-H)

International Journal of Geriatric Psychiatry ◽

10.1002/(sici)1099-1166(199910)14:10<807::aid-gps31>3.0.co;2-# ◽

1999 ◽

Vol 14 (10) ◽

pp. 807-820 ◽

Cited By ~ 48

Author(s):

Mary Ganguli ◽

Sanjay Dube ◽

Janet M. Johnston ◽

Rajesh Pandav ◽

Vijay Chandra ◽

...

Keyword(s):

Cognitive Impairment ◽

Depressive Symptoms ◽

Functional Impairment ◽

Elderly Population ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Rural Elderly ◽

Geriatric Depression

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Associations of cognitive condition with nutritional status in an elderly population: an analysis based on a 7-year database in Chongqing, the Southwest of China

10.21203/rs.3.rs-21402/v1 ◽

2020 ◽

Author(s):

Wuhan Yu ◽

Weihua Yu ◽

Xintong Liu ◽

Tianchi Wan ◽

Chenxi Chen ◽

...

Keyword(s):

Cognitive Impairment ◽

Cognitive Function ◽

Nutritional Status ◽

Elderly Population ◽

Short Form ◽

The Elderly ◽

Attention Problems ◽

Cognitive Status ◽

Cognitive Domain ◽

The Impact

Abstract Background: Malnutrition is one of the health problems in the elderly population, which increases the risk of poor clinical outcomes. The purpose of this investigation was to evaluate the nutritional status and cognitive function of an elderly Chinese population, to explore the association between malnutrition and cognitive condition as well as the cognitive domain.Methods: A cross-sectional study was conducted in 2365 participants aged 60 years or above from January 2013 to September 2019. We used the Mini Nutritional Assessment Short Form (MNA-SF), and the Mini Mental State Examination (MMSE) to assess the impact of malnutrition on cognitive function. Nutrition-associated factors were analyzed.Results: 33.45% of the participants were identified as malnutrition risk and 5.54% were malnourished, while 36.74% had cognitive impairments. 48.63% had nutritional deficits and 53.65% had cognitive impairment in those over 80 years old. Malnutrition is associated with global cognition (ρ= 0.349, P < 0.0001) and the cognitive domain particularly in orientation (ρ= 0.343, P < 0.0001). The impact was extended to attention and calculation (ρ=0.310, P < 0.0001) as well as language (ρ= 0.302, P < 0.0001) of those over 80 years of age. Malnutrition is an independent risk factor for cognitive impairment after adjusting for other variables (OR=2.004, 95% CI: 1.621-2.479).Conclusion: The prevalence of malnutrition and cognitive impairment was relatively high and increased with age. Malnutrition leads to cognitive decline and disorientation, and also contributes to attention problems, calculation problem and language impairment in the oldest old. Thus, clinicians should assess the nutritional and cognitive status of the elderly regularly to the early dictation and timely intervention.

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Nutritional status and cognitive impairment in elderly population in a rural area of Thrissur district, Kerala

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20180788 ◽

2018 ◽

Vol 5 (3) ◽

pp. 1218 ◽

Cited By ~ 1

Author(s):

Remya Ramachandran ◽

Jenyz M. Mundodan ◽

C. R. Saju ◽

Vidhu M. Joshy

Keyword(s):

Cognitive Impairment ◽

Nutritional Status ◽

Rural Area ◽

Elderly Population ◽

Nutritional Assessment ◽

Mmse Score ◽

Age Groups ◽

Mini Nutritional Assessment ◽

P Value ◽

Cross Sectional

Background: The past decade has witnessed a marked increase in elderly population of India. This rapid ageing will substantially increase the number of elderly individuals, who are affected by cognitive impairment. Recent studies suggest the association between malnutrition and cognitive impairment in elderly. This study aims to describe the nutritional status and cognitive impairment in elderly population in a rural area of Thrissur district, Kerala.Methods: A community based cross-sectional study was conducted in 100 elderly residents of Adat Panchayat, Thrissur, from January to April 2016. Data was collected using a pre-tested structured questionnaire, which included socio-demographic variables, self-reported physical morbidities, mini mental state examination (MMSE) scale and mini nutritional assessment (MNA) scale.Results: The prevalence of cognitive impairment and malnutrition in elderly was noted to be 55% and 12% respectively. Factors showing significant association with MMSE score included older age groups, female gender, elderly belonging to BPL families, financial dependence, single/widowed status and sleep difficulties. The association between cognitive impairment and nutritional status was found to be statistically significant with a p value of <0.001. A moderate to strong correlation was observed between MNA score and MMSE score (r=0.623).Conclusions: There is an association between cognitive impairment and nutritional deficit. Therefore it is essential to screen elderly for nutritional status while assessing cognitive impairment.

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