Association between the OXTR rs53576 genotype and latent profiles of post-traumatic stress disorder and depression symptoms in a representative sample of earthquake survivors

2019 ◽  
Vol 33 (2) ◽  
pp. 140-147
Author(s):  
Chengqi Cao ◽  
Li Wang ◽  
Jianhui Wu ◽  
Gen Li ◽  
Ruojiao Fang ◽  
...  
2018 ◽  
Vol 25 (9) ◽  
pp. 1285-1291
Author(s):  
Roberta Sonia Rodrigues Álvares ◽  
Ana Carolina Ferraz Mendonça-de-Souza ◽  
Antônio Fernando Araujo Duarte ◽  
Thaís Medeiros Gameiro ◽  
Nastassja Lopes Fischer ◽  
...  

We evaluated the participants’ negative affect, positive affect, post-traumatic stress disorder, and depression symptoms before and after a peacekeeping mission. Depression symptoms and positive affect after mission were significantly associated with exposure to stressful events during the mission, controlled by the respective characteristics before mission. Negative affect and post-traumatic stress disorder symptoms after mission had a tendency to be associated with exposure to stressful events during the mission, controlled by the respective characteristics before mission. In conclusion, even in healthy and physically active male peacekeepers, those more exposed to stressful events could be more vulnerable to present negative outcomes.


2015 ◽  
Vol 27 (3) ◽  
pp. 153-158 ◽  
Author(s):  
Pinar Guzel Ozdemir ◽  
İbrahim Kaplan ◽  
Cem Uysal ◽  
Mahmut Bulut ◽  
Abdullah Atli ◽  
...  

ObjectiveOxidative stress has been shown to play an important role in the pathogenesis of post-traumatic stress disorder (PTSD). Although there are some studies on oxidative stress and PTSD, there is no report available on the serum total oxidant and antioxidant status in earthquake survivors with PTSD. Therefore, this study aimed to investigate the serum total oxidant and antioxidant status in earthquake survivors with chronic PTSD.Material and MethodsThe study group included 45 earthquake survivors with PTSD and 40 earthquake survivors without PTSD. The oxidative status was determined using the total antioxidant status and total oxidant status (TOS) measurements and by calculating the oxidative stress index (OSI).ResultsThere were no statistically significant differences in the total antioxidant status, TOS, or OSI when comparing individuals with and without PTSD (all,p>0.05). There were no correlations between Clinician-Administered PTSD Scale scores and oxidant and antioxidant stress markers (all,p>0.05).ConclusionsOur results suggest that the total oxidant and antioxidant status may not affect earthquake survivors with PTSD. This is the first study to evaluate the oxidative status in earthquake survivors with PTSD. Further studies are necessary to confirm these findings.


2013 ◽  
Vol 67 (5) ◽  
pp. 363-364 ◽  
Author(s):  
Paolo Stratta ◽  
Roberto L. Bonanni ◽  
Patrizia Sanità ◽  
Stefano de Cataldo ◽  
Adriano Angelucci ◽  
...  

2020 ◽  
Vol 65 (8) ◽  
pp. 577-583 ◽  
Author(s):  
Michael C. Seto ◽  
Nicole C. Rodrigues ◽  
Elke Ham ◽  
Bonnie Kirsh ◽  
N. Zoe Hilton

Background And Methods: In this study, we surveyed 761 psychiatric hospital staff (69% women, 71% full-time, 56% nursing) regarding their exposure to trauma in the workplace; symptoms of post-traumatic stress disorder (PTSD), depression, and anxiety; help seeking; and perceived barriers for help seeking. Results: Significant proportions of staff met the screening cutoffs for probable PTSD (16%), depression (20%), and anxiety (16%). Comorbidity was high, with approximately half of those meeting the screening cutoff for PTSD also meeting the cutoffs for depression or anxiety. Only PTSD symptoms were uniquely associated with exposure to trauma in the workplace, but both PTSD and depression symptoms significantly predicted help seeking. Staff who met one or more screening cutoffs perceived more barriers to help seeking such as difficulty with accessing services. Conclusion: Implications for supporting psychiatric staff exposed to trauma are discussed.


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