DETERMINATION OF ACETYLSALICYLIC ACID IN PHARMACEUTICAL DRUGS BY TLC WITH DENSITOMETRIC DETECTION IN UV

2012 ◽  
Vol 35 (10) ◽  
pp. 1346-1363 ◽  
Author(s):  
Paulina Bocheńska ◽  
Alina Pyka
Keyword(s):  
Acetylsalicylic Acid ◽  
Pharmaceutical Drugs ◽  
Densitometric Detection

New Method for Simultaneous Determination of Ascorbic and Acetylsalicylic Acids in Effervescent Tablets

2017 ◽  
Vol 68 (11) ◽  
pp. 2495-2598 ◽  
Author(s):  
Simona Bungau ◽  
Delia Mirela Tit ◽  
Ciprian Iovan ◽  
Lucian Copolovici ◽  
Rica Boscencu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Acetylsalicylic Acid ◽  
Type Systems ◽  
Pharmaceutical Drugs ◽  
Important Goal ◽  
Mixture Ratio ◽  
Real Concentration ◽  
Preliminary Separation ◽  
Set Up

The determination of the real concentration in different pharmaceutical drugs represents a very important goal of the pharmaceutical industry. The main aim of the study was to set up a simple, cheap and rapid method in order to determine both ascorbic and acetylsalicylic acid content of effervescent tablets that could be found on the pharmaceutical market, without preliminary separation or extraction. For this purpose, a very simple and reliable clock method based on two Landolt-type systems of reactions, based on potentiometric techniques, has been developed. The method has been tested on different effervescent tablets which contain ascorbic acid and acetylsalicylic acid in different mixture ratio.

Determination of 7-ketocholesterol and 7-hydroxycholesterol in meat samples by TLC with densitometric detection

2003 ◽  
Vol 16 (3) ◽  
pp. 186-191 ◽  
Author(s):  
Beata Janoszka ◽  
Lidia Warzecha ◽  
Cezary Dobosz ◽  
Danuta Bodzek
Keyword(s):  
Densitometric Detection ◽  
Meat Samples

Optimization and Development of SPE and MAE Combined with UHPLCFD for the Determination of Acetylsalicylic Acid, Naproxen, Ibuprofen and Gemfibrozil in Sewage and Sludge Samples

2016 ◽  
Vol 12 (6) ◽  
pp. 545-552 ◽  
Author(s):  
A. Morales-Toledo ◽  
C. Afonso-Olivares ◽  
S. Montesdeoca-Esponda ◽  
R. Guedes-Alonso ◽  
Z. Sosa-Ferrera ◽  
...  
Keyword(s):  
Acetylsalicylic Acid

Simultaneous fluorimetric determination of acetylsalicylic acid metabolites in urine by partial least squares multivariate calibration

1995 ◽  
Vol 353 (2) ◽  
pp. 211-214 ◽  
Author(s):  
Arsenio Muñoz de la Peña ◽  
Isabel Durán-Merás ◽  
María D. Moreno ◽  
Francisco Salinas ◽  
María Martínez Galera
Keyword(s):  
Acetylsalicylic Acid ◽  
Least Squares ◽  
Partial Least Squares ◽  
Multivariate Calibration ◽  
Fluorimetric Determination ◽  
Acid Metabolites

scholarly journals Application of Liquid Chromatography to the Simultaneous Determination of Acetylsalicylic Acid, Caffeine, Codeine, Paracetamol, Pyridoxine, and Thiamine in Pharmaceutical Preparations

2001 ◽  
Vol 84 (3) ◽  
pp. 676-683 ◽  
Author(s):  
Natividad Ramos-Martos ◽  
Francisco Aguirre-Gómez ◽  
Antonio Molina-Díaz ◽  
Luis F Capitán-Vallvey
Keyword(s):  
Salicylic Acid ◽  
Acetylsalicylic Acid ◽  
Simultaneous Determination ◽  
Pharmaceutical Preparations ◽  
Reversed Phase ◽  
Liquid Chromatographic Method ◽  
Relative Standard ◽  
Phase Liquid ◽  
Liquid Chromatographic

Abstract This paper describes a rapid reversed-phase liquid chromatographic method, with UV detection, for the simultaneous determination of acetylsalicylic acid, caffeine, codeine, paracetamol, pyridoxine, and thiamine in pharmaceutical preparations. A reversed-phase C18 Nucleosil column is used. The mobile phase consists of 2 successive eluants: water (5 min) and acetonitrile–water (75 + 25, v/v; 9 min), both adjusted to pH 2.1 with phosphoric acid. Before determination acetylsalicylic acid is completely converted to salicylic acid by alkaline hydrolysis. Salicylic acid, caffeine, paracetamol, pyridoxine, and thiamine are all detected at 285 nm, whereas codeine is detected at 240 nm. Calibration curves were linear for salicylic acid, caffeine, paracetamol, and pyridoxine in the range of 50–500 mg/L, and for codeine and thiamine in the range of 50–1000 mg/L. The method was applied to the analysis of 13 fortified commercial pharmaceutical preparations. Recoveries ranged from 92.6 to 105.5%, with relative standard deviations of 1.1–5.8%.

scholarly journals Conversion of lignocellulosic agricultural wastes into adsorbents for pharmaceutical drugs

2019 ◽  
pp. 24-31
Author(s):  
Anca Cruceanu ◽  
Monica Alexandra Vaideanu ◽  
Rodica Zavoianu ◽  
Elena Bacalum ◽  
Octavian Dumitru Pavel
Keyword(s):  
Thermal Treatment ◽  
Carbon Content ◽  
Chemical Activation ◽  
Agricultural Wastes ◽  
Pharmaceutical Drugs ◽  
Adsorption Efficiency ◽  
Boehm Titration ◽  
The One ◽  
Amoxicillin Removal

Lignocellulosic agricultural wastes e.g. corn cobs, straws and corn stalks were converted into carbonaceous adsorbents using a sequence of thermal and chemical activation processes. The derived solids obtained after each type of activation were characterized by determination of fix carbon content, iodine number, Boehm titration and DRIFT spectrometry. The results obtained at the adsorption tests were well correlated to those of the characterization, showing that the most promising adsorbents for amoxicillin removal were those submitted to a thermal treatment followed by a chemical alkaline activation, followed by washing and a secondary thermal treatment. The most promising bio-based adsorbent was the one derived from corn stalks (90.6% adsorption efficiency).

UV SPECTROPHOTOMETRIC FLOW-THROUGH MULTIPARAMETER SENSOR FOR THE SIMULTANEOUS DETERMINATION OF ACETAMINOPHEN, ACETYLSALICYLIC ACID, AND CAFFEINE

2002 ◽  
Vol 35 (15) ◽  
pp. 2433-2447 ◽  
Author(s):  
A. Domínguez Vidal ◽  
J. F. García Reyes ◽  
P. Ortega Barrales ◽  
A. Molina Díaz
Keyword(s):  
Acetylsalicylic Acid ◽  
Simultaneous Determination ◽  
Flow Through

Determination of budesonide R(+) and S(−) isomers in pharmaceuticals by thin-layer chromatography with UV densitometric detection

2002 ◽  
Vol 56 (11-12) ◽  
pp. 759-762 ◽  
Author(s):  
J. Krzek ◽  
U. Hubicka ◽  
M. Dabrowska-Tylka ◽  
E. Leciejewicz-Ziemecka
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Densitometric Detection ◽  
Layer Chromatography
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