Phytochemicals, antioxidant activity and hepatoprotective effect of ginger (Zingiber officinale) on diethylnitrosamine toxicity in rats

Biomarkers ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 436-447 ◽  
Author(s):  
Abdelgawad Fahmi ◽  
Naglaa Hassanen ◽  
Mariam Abdur-Rahman ◽  
Engy Shams-Eldin
2019 ◽  
Vol 14 (5) ◽  
pp. 386-390
Author(s):  
Javad Aliakbarlu ◽  
Surur K. Sadaghiani ◽  
Shadieh Mohammadi

Spatula DD ◽  
2011 ◽  
Vol 1 (1) ◽  
pp. 1 ◽  
Author(s):  
Ragaa AlTahtawy ◽  
Amal ElBastawesy ◽  
Mohamad Monem ◽  
Zekry Zekry ◽  
Hussain AlMehdar ◽  
...  

2016 ◽  
Vol 78 (11-2) ◽  
Author(s):  
Mohd Faez Sharif ◽  
Muhd Taha Bennett

Food ingredients derived from plants are a rich source of polyphenols. In recent times, polyphenols have become popular for their therapeutic properties as antioxidants. 6-gingerol, the main bioactive phenolic compound in Zingiber officinale, is well known for its free radical scavenging capabilities in treating multiple ailments. The most common method for extracting polyphenols from plant materials is through the use of solvents. The extraction of polyphenols from plant matrix is largely dependent on the type of solvent used and the extraction method employed. However, due to the complexity of plant chemistry there is no obvious choice in solvent or extraction method. In this study we made use of three different solvents; acetone, ethanol, and methanol. Variations of two different methods were used.  The reflux was run for 30 minutes at 95  and maceration was done at room temperature for 8 hours. Between the different methods, maceration extracts generally showed better TPC, 6-gingerol content and antioxidant activity. Ethanol was significantly the best extracting solvent due to its higher polarity index. While the maceration ethanol extracts significantly had the highest TPC and 6-gingerol content, its antioxidant activity was not significantly different from the ethanol reflux extracts. A significantly positive correlation was determined between TPC and antioxidant activity, with reflux extracts having a better correlation than the maceration extracts. A significant positive correlation was also drawn between TPC and 6-gingerol content.


Author(s):  
Bui Thanh Tung ◽  
Dang Kim Thu ◽  
Nguyen Thi Kim Thu ◽  
Nguyen Thanh Hai

AbstractBackgroundRoscoe has been used in traditional medicine for the treatment of neurological disorder. This study aimed to investigate the phenolic contents, antioxidant, acetylcholinesterase enzyme (AChE) inhibitory activities of different fraction ofMethodsThe roots ofResultsOur data showed that the total phenolic content of EtOAc fraction was highest equivalents to 35.2±1.4 mg quercetin/g of fraction. Our data also demonstrated that EtOAc fraction had the strongest antioxidant activity with ICConclusionsOur results suggest that the EtOAc fraction of


2021 ◽  
Vol 23 (06) ◽  
pp. 170-179
Author(s):  
Dr. Dhana Rangesh Kumar V ◽  
◽  
M. Sharu latha ◽  
Benitta Soosan Thomas ◽  
◽  
...  

Herbal plants produce a diverse range of bioactive molecules, making them a rich source of different types of medicines. Thus, proper scientific evidence or assessment has become the criteria for the acceptance of herbal health claims. Plants-based antioxidants are now preferred to synthetic ones because of safety concerns. There is an increasing interest in natural antioxidants e.g. Polyphenols, present in medicinal and dietary plants, which might help prevent oxidative damage. Natural antioxidant increases the antioxidant capacity of plasma and reduces the risk of disease. As such developing a polyhedral formulation will definitely produce a synergistic effect as needed comparable to standard drugs that are available in the market all over the world. The polyherbal formulation, which has a combination of medicinal herbs such as Zingiber officinale (sukku), Nigella sativa (karunjeeragam), Plectranthus amboinicus (karpooravalli), Pipeer cubeba (Vaal melagu), Trigonella foenum graecum (venthayam) powder was tested for its an antioxidant activity phenolic and alkaloid contents in vitro. The purpose of the present study was to investigate the In-vitro antioxidant phenolic and alkaloid content of polyherbal formulation and its application for treating life-threatening diseases such as cancer, cardiac disease, and diabetes mellitus. In this paper, we report the result of such studies in order to orient future investigations towards the finding of new, potent safe, and easily available food antioxidants.


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