scholarly journals Antioxidant activity and hepatoprotective effect of pomegranate peel and whey powders in rats

2013 ◽  
Vol 58 (1) ◽  
pp. 27-32 ◽  
Author(s):  
I.S. Ashoush ◽  
O.I. El-Batawy ◽  
Gehan A. El-Shourbagy
Keyword(s):  
Antioxidant Activity ◽  
Hepatoprotective Effect ◽  
Pomegranate Peel

scholarly journals Effect of Chitosan–Pullulan Composite Edible Coating Functionalized with Pomegranate Peel Extract on the Shelf Life of Mango (Mangifera indica)

Coatings ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 764
Author(s):  
Nishant Kumar ◽  
Pratibha ◽  
Neeraj ◽  
Anka Trajkovska Petkoska ◽  
Sawsan Ali AL-Hilifi ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Shelf Life ◽  
Mangifera Indica ◽  
Storage Period ◽  
Edible Coating ◽  
Postharvest Quality ◽  
Pomegranate Peel ◽  
Preservation Method ◽  
Pomegranate Peel Extract ◽  
Peel Extract

The polysaccharide based composite biomaterial (coating) used in preserving fruits and vegetables during storage is attracting increased attention as it is biodegradable material that prolongs shelf life. In the present investigation, chitosan–pullulan (50:50) composite edible coating was prepared with pomegranate peel extract (0.02 g/mL) as an active antioxidant agent. The effect of treatment with pomegranate peel extract enriched chitosan–pullulan composite edible coating on the shelf life of mango fruits during 18 days of storage period at room (23 °C) and cold (4 °C) temperature was evaluated. Results of the present study demonstrated that the application of chitosan–pullulan composite edible coating significantly (p ≤  0.05) influences the storage life of mango fruits at both storage temperatures. The chitosan–pullulan composite edible coating reduced the physiological loss in weight (PLW), and maintained total soluble solids (TSS), acidity and pH of coated mango fruits as compared to the control. In addition, fruit sensory quality such as freshness, color, taste and texture were also retained by the treatment. Furthermore, sustained firmness, phenolic content and antioxidant activity confirmed the effectiveness of the pomegranate peel extract enriched chitosan–pullulan composite edible coating on mango fruits. The phenolic, flavonoid and antioxidant activity of coated fruits were retained by pomegranate peel rich edible coating. Therefore, the chitosan–pullulan (50:50) combination with pomegranate peel extract can be used as an alternative preservation method to prolong the shelf life of mango fruits at room and cold storage conditions. However, more in-depth studies are required at farm and transit level without affecting the postharvest quality of mango fruits, providing more revenue for farmers and minimizing postharvest losses.

scholarly journals Polyphenol Enriched Extract of Pomegranate Peel; A Novel Precursor for the Biosynthesis of Zinc Oxide Nanoparticles and Application in Sunscreens

2020 ◽  
Vol 27 (1) ◽  
pp. 102-110
Author(s):  
Maryam Kokabi ◽  
Samad Nejad Ebrahimi
Keyword(s):  
Antioxidant Activity ◽  
Zinc Oxide ◽  
Ir Spectroscopy ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Pomegranate Peel ◽  
Ft Ir ◽  
Oil Emulsions ◽  
Ft Ir Spectroscopy

Background: Green synthesized nanoparticles (NPs) from agricultural wastes is an area of great interest due to it is eco-friendly and profitable. Zinc oxide is an inorganic UV-filter commonly used as UV-blocker in a different industry. Methods: Zinc oxide nanoparticles (ZnO NPs) were successfully biosynthesized using Zn(NO3)2 as a substrate by polyphenol enriched fraction (PEF) of pomegranate peel. The biological activity of ZnO NPs was evaluated using MBC and MIC tests for antibacterial and DPPH assay for antioxidant potential. Sunscreen potential of NPs was determined after applying them in water-in-oil emulsions. Results: UV-Vis and FT-IR spectroscopy techniques confirmed the formation of ZnO NPs. FE-SEM characterized the morphology and purity of the biosynthesized NPs with EDAX and XRD data. The average crystalline size of ZnO NPs was found to be 22 nm. FT-IR spectroscopy revealed the role of phenolic compounds in the formation and stability of ZnO NPs. The antibacterial activity of PEF and its biosynthesized ZnO was evaluated against Staphylococcus aureus and Escherichia coli. The prepared NPs showed a higher antibacterial effect than the commercial ZnO NPs. Interestingly, the antioxidant activity was also detected for obtained NPs. The PEF powder also exhibited higher antibacterial and antioxidant activity than the standards. Furthermore, the in vitro sun protection factors were estimated after applying NPs in water-in-oil emulsions. Conclusion: This study highlighted the possibility of using PEF of pomegranate peel for the biosynthesis of ZnO NPs as well as applying its NPs in sunscreens to achieve a safe alternative to harmful chemical UV-filters commonly used in cosmetics.

Phytochemicals, antioxidant activity and hepatoprotective effect of ginger (Zingiber officinale) on diethylnitrosamine toxicity in rats

Biomarkers ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 436-447 ◽  
Author(s):  
Abdelgawad Fahmi ◽  
Naglaa Hassanen ◽  
Mariam Abdur-Rahman ◽  
Engy Shams-Eldin
Keyword(s):  
Antioxidant Activity ◽  
Zingiber Officinale ◽  
Hepatoprotective Effect

Correlation Between Antioxidant Activity and Hepatoprotective Effect of a Vegetal Bioproduct

2010 ◽  
Vol 523 (1) ◽  
pp. 228/[800]-235/[807]
Author(s):  
Cornelia Nichita ◽  
Georgeta Neagu ◽  
Virginia Vulturescu ◽  
Radu Albulescu ◽  
Viorel Vulturescu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Hepatoprotective Effect

Actinidia rubricaulisAttenuates Hepatic Fibrosis Induced by Carbon Tetrachloride in Rats

2007 ◽  
Vol 35 (01) ◽  
pp. 81-88 ◽  
Author(s):  
Jung-Chun Liao ◽  
Kun-Hung Lin ◽  
Hao-Yuan Cheng ◽  
Jin-Bin Wu ◽  
Ming-Tsuen Hsieh ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Carbon Tetrachloride ◽  
Liver Injury ◽  
Experimental Period ◽  
Hepatoprotective Effect ◽  
Glutamate Pyruvate Transaminase ◽  
Chronic Liver Injury ◽  
Glutamate Pyruvate ◽  
Ethanol Extracts ◽  
Serum Glutamate

The purpose of this study was to evaluate the antioxidant activity and hepatoprotective effect of ethanol extracts of Actinidia rubricaulis (AR) on chronic liver injury induced by carbon tetrachloride ( CCl4) in rats. CCl4(20%, 0.5 ml/rat) was given twice a week for 8 weeks, and animals received AR throughout the entire experimental period. AR reduced the elevated levels of serum glutamate-oxalate-transaminase (sGOT) and glutamate-pyruvate-transaminase (sGPT) caused by CCl4at weeks 1,3,6, and 8. The biochemical data were consistent with those of the histological observations. The AR extract recovered the CCl4-induced liver injury and showed antioxidant effect in assays of antioxidant enzyme activity, such as SOD, GSH-Px and GSH-Rd. Based on these results, we suggest that the hepatoprotective effect of the AR is related to its antioxidant activity.

scholarly journals Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Hongtan Wu ◽  
Gang Zhang ◽  
Lisen Huang ◽  
Haiyue Pang ◽  
Na Zhang ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Liver Injury ◽  
Target Genes ◽  
Therapeutic Potential ◽  
Radical Scavenging ◽  
Hepatoprotective Effect ◽  
Nuclear Accumulation ◽  
Related Factor ◽  
Hepatic Expression ◽  
Phenolic Components

Folium Microcos (FM), the leaves of Microcos paniculata L., shows various biological functions including antioxidant activity and α-glucosidase inhibitory effect. However, its therapeutic potential in acute liver injury is still unknown. This study investigated the hepatoprotective effect and underlying mechanisms of the polyphenol-enriched fraction (FMF) from Folium Microcos. FMF exhibited strong free radical scavenging activities and prevented HepG2/Hepa1–6 cells from hydrogen peroxide- (H2O2-) induced ROS production and apoptosis in vitro. Antioxidant activity and cytoprotective effects were further verified by alleviating APAP-induced hepatotoxicity in mice. Western blot analysis revealed that FMF pretreatment significantly abrogated APAP-mediated phosphorylation of MAPKs, activation of proapoptotic protein caspase-3/9 and Bax, and restored expression of antiapoptotic protein Bcl2. APAP-intoxicated mice pretreated with FMF showed increased nuclear accumulation of nuclear factor erythroid 2-related factor (Nrf2) and elevated hepatic expression of its target genes, NAD(P)H:quinine oxidoreductase 1 (NQO1) and hemeoxygenase-1(HO-1). HPLC analysis revealed the four predominantly phenolic compounds present in FMF: narcissin, isorhamnetin-3-O-β-D-glucoside, isovitexin, and vitexin. Consequently, these findings indicate that FMF possesses a hepatoprotective effect against APAP-induced hepatotoxicity mainly through dual modification of ROS/MAPKs/apoptosis axis and Nrf2-mediated antioxidant response, which may be attributed to the strong antioxidant activity of phenolic components.

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